1H T1 and T2 measurements of the MR imaging contrast agents Gd-DTPA and Gd-DTPA BMA at 1.5T

European Radiology

Volumn 7, Issue 2, 1997, Pages 264-274

  Reichenbach, J R ^a,b   Hacklander Th ^a   Harth, T ^a   Hofer, M ^a   Rassek, M ^a   Modder, U ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Contrast agents; Gd DTPA; Gd DTPA BMA; MR imaging; Relaxation; Relaxivity

Indexed keywords

CONTRAST MEDIUM; DIAGNOSTIC AGENT; DRUG DERIVATIVE; GADODIAMIDE; GADOLINIUM; GADOLINIUM PENTETATE; ORGANOMETALLIC COMPOUND; PENTETIC ACID;

ARTICLE; IMAGE QUALITY; NUCLEAR MAGNETIC RESONANCE IMAGING;

CONTRAST MEDIA; GADOLINIUM; GADOLINIUM DTPA; MAGNETIC RESONANCE IMAGING; ORGANOMETALLIC COMPOUNDS; PENTETIC ACID; PHANTOMS, IMAGING;

EID: 0030636225     PISSN: 09387994     EISSN: None     Source Type: Journal    
DOI: 10.1007/s003300050149     Document Type: Article

References (37)

1. Rosen BR, Belliveau JW, Vevea JM, Brady TJ (1990) Perfusion imaging with NMR contrast agents. Magn Reson Med 14: 249
2. Belliveau JW, Kennedy DN, McKinstry RC, Buchbinder BR, Weiskoff RM, Cohen MS, Vevea JM, Brady TJ, Rosen BR (1991) Functional mapping of the human visual cortex by magnetic resonance imaging. Science 254: 716
3. Edelman RR, Mattle HP, Atkinson DJ, Hill T, Finn JP, Mayman C, Ronthal M, Hoogewould HM, Kleefield J (1990) Cerebral blood flow assessment with dynamic contrast-enhanced T2*-weighted MR imaging at 1.5T. Radiology 176: 211
4. Hackländer T, Hofer M, Paselk C, Modder U (1993) Funktionelle Bildgebung des Gehirns mit niedrig dosiertem GdDTPA und Turbo-FLASH Sequenzen. RöFo 158: 348
5. Dean BL, Lee C, Kirsch JE, Runge VM, Dempsey RM, Pettigrew LC (1992) Cerebral hemodynamics and cerebral blood volume: MR assessment using gadolinium contrast agent and T1-weighted Turbo-FLASH imaging. AJNR 13: 39
6. Wendland MF, Saeed M, Yu KK, Roberts TPL, Lauerma K, Derugin N, Varadarajan J, Watson AD, Higgins CB (1994) Inversion recovery EPI of bolus transit in rat myocardium using intravascular and extravascular gadolinium-based MR contrast media: dose effects on peak signal enhancement. Magn Reson Med 32: 319
7. Zhou X, Alameda JC Jr, Magin RL, Lauterbur PC (1989) Abstracts of the 8th Annual Meeting of the International Society for Magnetic Resonance in Medicine, Amsterdam, The Netherlands, pp 1121
8. Wiener EC, Brechbiel MW, Brothers H, Magin RL, Gansow OA, Tomalia DA, Lauterbur PC (1994) Dendrimer-based metal chelates: a new class of magnetic resonance imaging contrast agents. Magn Reson Med 31: 1
9. Cavagna F, Luchinat C, Scozzafava A, Xia Z (1994) Polymetallic macromolecules are potential contrast agents of improved efficiency. Magn Reson Med 31: 58
10. Weinmann HJ, Brasch RC, Press WR, Wesbey GE (1984) Characteristics of gadolinium-DTPA complex: a potential NMR contrast agent. AJR 142: 619
11. Cacheris WP, Quay SC, Rocklage SM (1990) The relationship between thermodynamics and the toxicity of gadolinium complexes. Magn Reson Imaging 8: 467
12. Rocklage SM, Worah D, Kim SH (1991) Metal ion release from paramagnetic chelates: What is tolerable? Magn Reson Med 22: 216
13. Geraldes CFGC, Sherry AD, Brown RD III, Koenig SH (1986) Magnetic field dependence of solvent proton relaxation rates induced by Gd(III) and Mn(II) complexes of various polyaza macrocyclic ligands: implication for NMR imaging. Magn Reson Med 3: 242
14. Lauffer RB (1987) Paramagnetic metal complexes as water proton relaxation agents for NMR imaging: theory and design. Chem Rev 87: 901
15. Tweedle MF, Brittain HG, Eckelman WC, Gaughan GT, Hagan JJ, Wedeking PW, Runge VM (1988) Principles of contrast-enhanced MRI. In: Partain CL, Price RR, Patton JA, Kulkarni MV, James AE Jr (eds) Magnetic resonance imaging, vol 2, 2nd edn. Saunders, Philadelphia, pp 793-809
16. Koenig SH, Brown RD (1987) Relaxometry of tissue. In: Gupta RK (ed) NMR spectroscopy of cells and organisms, vol 2. CRC Press, Boca Raton, Florida, pp 75-114
17. Koenig SH, Brown RD III (1991) Field-cycling relaxometry of protein solutions and tissue: implications for MRI. Prog NMR Spectr 22: 487
18. Void RL, Waugh JS, Klein MP, Phelps DE (1968) Measurement of spin relaxation in complex systems. J Chem Phys 48: 3831
19. Haase A, Frahm J, Matthaei D, Hänicke W, Merboldt KD (1986) FLASH imaging. Rapid NMR imaging using low flip-angle pulses. J Magn Reson 67: 258
20. Haase A (1990) Snapshot FLASH MRI. Applications to T1, T2, and chemical shift imaging. Magn Reson Med 13: 77
21. Blüml S, Schad LR, Stepanow B, Lorenz WJ (1993) Spin-lattice relaxation time measurement by means of a turbo FLASH technique. Magn Reson Med 30: 289
22. Holsinger AE, Riederer SJ (1990) The importance of phase-encoding order in ultra-short TR snapshot MR imaging. Magn Reson Med 16: 481
23. Marquardt DW (1963) An algorithm for least-squares estimation of nonlinear parameters. J Soc Indust Appl Math 11: 431
24. Press WH, Teukolsky SA, Vetterling WT, Flannery BP (1992) Numerical recipes in C. The art of scientific computing. Cambridge University Press, Cambridge
25. Graumann R, Oppelt A, Stetter E (1986) Multiple-spin-echo imaging with a 2D Fourier method. Magn Reson Med 3: 707
26. Carr HY, Purcell EM (1954) Effects of diffusion on free precession in nuclear magnetic resonance experiments. Phys Rev 94: 630
27. Meiboom S, Gill D (1958) Modified spin-echo method for measuring nuclear relaxation times. Rev Sci Instr 29: 688
28. 1 of the echo amplitudes from multiple spin-echo sequences with equidistant echoes: simulation studies. Magn Reson Imaging 11: 197
29. 1 of the echo amplitudes using a multiple spin-echo scheme. Magn Reson Imaging 11: 1185
30. Donahue KM, Burstein D, Manning WJ, Gray ML (1994) Studies of Gd-DTPA relaxivity and proton exchange rates in tissue. Magn Reson Med 32: 66
31. Sze G, Brant-Zawadzki M, Haughton VM, Maravilla KR, McNamara MT, Kumar AJ, Aisen AM, Dreisbach JN, Bradley Jr. WG, Weinreb JC, Drayer BP, Tsuruda JS, Hesselink JR, Johnson CE, Zimmermann RD, Weingast GR (1991) Multicenter study of gadodiamide injection as a contrast agent in MR imaging of the brain and spine. Radiology 181: 693
32. Elst LV, Haverbeke Y van, Goudemant JF, Muller RN (1994) Stability assessment of gadolinium complexes by P-31 and H-1 relaxometry. Magn Reson Med 31: 437
33. Fransson A, Ericson A, Jung B, Henriksson U (1989) Resolution of biexponential transverse relaxation in magnetic resonance imaging. Phys Med Biol 34: 305
34. Abragam A (1961) The principles of nuclear magnetism. Oxford University, London
35. Solomon I (1955) Relaxation processes in a system of two spins. Phys Rev 99: 559
36. Bloembergen NJ (1955) Proton relaxation times in paramagnetic solutions. J Chem Phys 27: 572
37. Koenig SH, Spiller M, Brown III RD, Wolf GL (1986) Relaxation of water protons in the intra-and extracellular regions of blood containing Gd(DTPA). Magn Reson Med 3: 791