Cytoprotective Response of A1, a Bcl-2 Homologue Expressed in Mature Human Neutrophils and Promyelocytic HL-60 Cells, to Oxidant Stress-Induced Cell Death

Journal of Biomedical Science

Volumn 11, Issue 2, 2004, Pages 214-227

  Liu, Chien Ying ^a   Chuang, Peter I ^b   Chou, Chun Liang ^a   Lin, Shu Min ^a   Chen, Hao Cheng ^a   Chou, Paichien ^a   Liu, Yun Hen ^a   Yu, Chih Ten ^a   Wang, Chun Hua ^a   Lin, Horng Chyuan ^a   Kuo, Han Pin ^a  

^a CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

A1; Apoptosis; Cell death; HL 60 cells; Neutrophils; Reactive oxygen intermediate

Indexed keywords

HYDROGEN PEROXIDE; PROTEIN BCL 2;

ARTICLE; CANCER CELL; CELL DEATH; CELL PROTECTION; CELL STRAIN HL 60; CONTROLLED STUDY; CORRELATION ANALYSIS; GENE OVEREXPRESSION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NEUTROPHIL; OXIDATIVE STRESS; PRECURSOR; PRIORITY JOURNAL; PROMYELOCYTIC LEUKEMIA; SEQUENCE HOMOLOGY; STEM CELL;

APOPTOSIS; CELLS, CULTURED; DNA-BINDING PROTEINS; GRANULOCYTE COLONY-STIMULATING FACTOR; HL-60 CELLS; HUMANS; HYDROGEN PEROXIDE; NEUTROPHILS; OXIDATIVE STRESS; PEROXYNITROUS ACID; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-BCL-2; REPLICATION PROTEIN C; TRANSFECTION;

EID: 10744232836     PISSN: 10217770     EISSN: 14230127     Source Type: Journal    
DOI: 10.1159/000076034     Document Type: Article

References (84)

1. Ackermann EJ, Taylor JK, Narayana R, Bennett CF. The role of antiapoptotic Bcl-2 family members in endothelial apoptosis elucidated with antisense oligonucleotides. J Biol Chem 274:11245-11252;1999.
2. Adrie C, Richter C, Bachelet M, Banzet N, Francois D, Dinh-Xuan AT, Dhainaut JF, Polla BS, Richard MJ. Contrasting effects of NO and peroxynitrites on HSP70 expression and apoptosis in human monocytes. Am J Physiol Cell Physiol 279:C452-460;2000.
3. Albina JE, Martin BA, Henry WL Jr, Louis CA, Reichner JS. B cell lymphoma-2 transfected P815 cells resist reactive nitrogen intermediate- mediated macrophage-dependent cytotoxicity. J Immunol 157:279-283;1996.
4. Beckman JS, Beckman TW, Chen J, Marshall PA, Freeman BA. Apparent hydroxyl radical production by peroxynitrite: Implications for endothelial injury from nitric oxide and superoxide. Proc Natl Acad Sci USA 87:1620-1624;1990.
5. Blaylock MG, Cuthbertson BH, Galley HF, Ferguson NR, Webster NR. The effect of nitric oxide and peroxynitrite on apoptosis in human polymorphonuclear leukocytes. Free Radic Biol Med 25:748-752;1998.
6. Chau YP, Shiah SG, Don MJ, Kuo ML. Involvement of hydrogen peroxide in topoisomerase inhibitor beta-lapachone-induced apoptosis and differentiation in human leukemia cells. Free Radic Biol Med 24:660-670;1998.
7. Cherbonnel-Lasserre C, Dosanjh MK. Suppression of apoptosis by overexpression of Bcl-2 or Bcl-xL promotes survival and mutagenesis after oxidative damage. Biochemie 79:613-617;1997.
8. Chuang PI, Yee E, Karsan A, Winn RK, Harlan JM. A1 is a constitutive and inducible Bcl-2 homologue in mature human neutrophils. Biochem Biophys Res Commun 249:361-365;1998.
9. Dancey JT, Deubelbeiss KA, Harker LA, Finch CA. Neutrophil kinetics in man. J Clin Invest 58:705-715;1976.
10. Dekhuijzen PN, Aben KK, Dekker I, Aarts LP, Wielders PL, Bast A. Increased exhalation of hydrogen peroxide in patients with stable and unstable chronic obstructive pulmonary disease. Am J Respir Crit Care Med 154:813-816;1996.
11. 2+ pool depletion. Oncogene 12:2051-2055;1996.
12. Dohlman AW, Black HR, Royall JA. Expired breath hydrogen peroxide is a marker of acute airway inflammation in pediatric patients with asthma. Am Rev Respir Dis 148:955-960;1993.
13. Dumont A, Hehner SP, Hofmann TG, Ueffing M, Droge W, Schmitz ML. Hydrogen peroxide-induced apoptosis is CD95-independent, requires the release of mitochondria-derived reactive oxygen species and the activation of NF-kappaB. Oncogene 18:747-757;1999.
14. English D, Anderson BR. Single-step separation of red blood cells, granulocytes and mononuclear leukocytes on discontinuous density gradients of Ficoll-Hypaque. J Immunol Methods 5:249-252;1974.
15. Evans TJ, Buttery LD, Carpenter A, Springall DR, Polak JM, Cohen J. Cytokine-treated human neutrophils contain inducible nitric oxide synthase that produces nitration of ingested bacteria. Proc Natl Acad Sci USA 93:9553-9558;1996.
16. Fang W, Rivard JJ, Ganser JA, LeBien TW, Nath KA, Mueller DL, Behrens TW. Bcl-xL rescues WEHI 231 B lymphocytes from oxidant-mediated death following diverse apoptotic stimuli. J Immunol 155:66-75;1995.
17. Fortenberry JD, Owens ML, Brown MR, Atkinson D, Brown LA. Exogenous nitric oxide enhances neutrophil cell death and DNA fragmentation. Am J Respir Cell Mol Biol 18:421-428;1998.
18. Frasch SC, Nick JA, Fadok VA, Bratton DL, Worthen GS, Henson PM. p38 mitogen-activated protein kinase-dependent and -independent intracellular signal transduction pathways leading to apoptosis in human neutrophils. J Biol Chem 273:8389-8397;1998.
19. Gorman A, McGowan A, Cotter TG. Role of peroxide and superoxide anion during tumour cell apoptosis. FEBS Lett 404:27-33;1997.
20. Hamasaki A, Sendo F, Nakayama K, Ishida N, Negishi I, Nakayama K, Hatakeyama S. Accelerated neutrophil apoptosis in mice lacking A1-a, a subtype of the bcl-2-related A1 gene. J Exp Med 188:1985-1992;1998.
21. Hockenbery DM, Oltvai ZN, Yin XM, Milliman CL, Korsmeyer SJ. Bcl-2 functions in an antioxidant pathway to prevent apoptosis. Cell 75:241-251;1993.
22. Huang C, Li J, Zheng R, Cui K. Hydrogen peroxide-induced apoptosis in human hepatoma cells is mediated by CD95(APO-1/Fas) receptor/ligand system and may involve activation of wild-type p53. Mol Biol Rep 27:1-11;2000.
23. Hsieh SC, Huang MH, Tsai CY, Tsai YY, Tsai ST, Sun KH, Yu HS, Han SH, Yu CL. The expression of genes modulating programmed cell death in normal human polymorphonuclear neutrophils. Biochem Biophys Res Commun 233:700-706;1997.
24. Ikeda I, Kasajima T, Ishiyama S, Shimojo T, Takeo Y, Nishikawa T, Kameoka S, Hiroe M, Mitsunaga A. Distribution of inducible nitric oxide synthase in ulcerative colitis. Am J Gastroenterol 92:1339-1341;1997.
25. Ishikawa Y, Kitamura M. Anti-apoptotic effect of quercetin: Intervention in the JNK- and ERK-mediated apoptotic pathways. Kidney Int 58:1078-1087;2000.
26. Iwai K, Miyawaki T, Takizawa T, Konno A, Ohta K, Yachie A, Seki H, Taniguchi N. Differential expression of bcl-2 and susceptibility to anti-Fas-mediated cell death in peripheral blood lymphocytes, monocytes, and neutrophils. Blood 84:1201-1208;1994.
27. Karsan A, Yee E, Kaushansky K, Harlan JM. Cloning of human Bcl-2 homologue: Inflammatory cytokines induce human A1 in cultured endothelial cells. Blood 87:3089-3096;1996.
28. Karsan A, Yee E, Harlan JM. Endothelial cell death induced by tumor necrosis factor-alpha is inhibited by the Bcl-2 family member, A1. J Biol Chem 271:27201-27204;1996.
29. Kasahara Y, Iwai K, Yachie A, Ohta K, Konno A, Seki H, Miyawaki T, Taniguchi N. Involvement of reactive oxygen intermediates in spontaneous and CD95 (Fas/APO-1)-mediated apoptosis of neutrophils. Blood 89:1748-1753;1997.
30. Khwaja A, Tatton L. Caspase-mediated proteolysis and activation of protein kinase C delta plays a central role in neutrophil apoptosis. Blood 94:291-301;1999.
31. Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pals ST, Vanoers MH. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 84:1415-1420;1994.
32. Kooy NW, Lewis SJ, Royall JA, Ye YZ, Kelly DR, Beckman JS. Extensive tyrosine nitration in human myocardial inflammation: Evidence for the presence of peroxynitrite. Crit Care Med 25:812-819;1997.
33. Kooy NW, Royall JA, Ye YZ, Kelly DR, Beckman JS. Evidence for in vivo peroxynitrite production in human acute lung injury. Am J Respir Crit Care Med 151:1250-1254;1995.
34. Kozopas KM, Yang T, Buchan HL, Zhou P, Craig RW. MCL1, a gene expressed in programmed myeloid cell differentiation, has sequence similarity to Bcl-2. Proc Natl Acad Sci USA 90:3516-3520;1993.
35. Kuo ML, Shiah SG, Wang CJ, Chuang SE. Suppression of apoptosis by Bcl-2 to enhance benzene metabolites-induced oxidative DNA damage and mutagenesis: A possible mechanism of carcinogenesis. Mol Pharmacol 55:894-901;1999.
36. Lee JE, Sohn J, Lee JH, Lee KC, Son CS, Tockgo YC. Regulation of Bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells. Exp Mol Med 32:42-46;2000.
37. Lee Y, Shacter E. Bcl-2 does not protect Burkitt's lymphoma cells from oxidant-induced cell death. Blood 89:4480-4492;1997.
38. Li J, Huang CY, Zheng RL, Cui KR, Li JF. Hydrogen peroxide induces apoptosis in human hepatoma cells and alters cell redox status. Cell Biol Int 24:9-23;2000.
39. Lin EY, Orlofsky A, Berger MS, Prystowsky MB. Characterization of A1, a novel hemopoietic-specific early-response gene with sequence similarity to bcl-2. J Immunol 151:1979-1988;1993.
40. Lin EY, Orlofsky A, Wang HG, Reed JC, Prystowsky MB. A1, a Bcl-2 family member, prolongs cell survival and permits myeloid differentiation. Blood 87:983-992;1996.
41. Lin KT, Xue JY, Nomen M, Spur B, Wong PY. Peroxynitrite-induced apoptosis in HL-60 cells. J Biol Chem 270:16487-16490;1995.
42. Lin KT, Xue JY, Wong PY. Mechanisms of peroxynitrite-induced apoptosis in HL-60 cells. Adv Exp Med Biol 469:569-575;1999.
43. Liu F, Wu HY, Wesselschmidt R, Kornaga T, Link DC. Impaired production and increased apoptosis of neutrophils in granulocyte colony-stimulating factor receptor-deficient mice. Immunity 5:491-501;1996.
44. Liu GY, Chen KJ, Lin-Shiau SY, Lin JK. Peroxyacetyl nitrate-induced apoptosis through generation of reactive oxygen species in HL-60 cells. Mol Carcinog 25:196-206;1999.
45. Loukides S, Horvath I, Wodehouse T, Cole PJ, Barnes PJ. Elevated levels of expired breath hydrogen peroxide in bronchiectasis. Am J Respir Crit Care Med 158:991-994;1998.
46. Lundqvist-Gustafsson H, Bengtsson T. Activation of the granule pool of the NADPH oxidase accelerates apoptosis in human neutrophils. J Leukoc Biol 65:196-204;1999.
47. Matute B-G, Liles WC, Radella F 2nd, Steinberg KP, Ruzinski JT, Jonas M, Chi EY, Hudson LD, Martin TR. Neutrophil apoptosis in the acute respiratory distress syndrome. Am J Respir Crit Care Med 156:1969-1977;1997.
48. Melkonyan H, Sorg C, Klempt M. Electroporation efficiency in mammalian cells is increased by dimethyl sulfoxide (DMSO). Nucleic Acids Res 24:4356-4357;1996.
49. Messmer UK, Reed UK, Brune B. Bcl-2 protects macrophages from nitric oxide-induced apoptosis. J Biol Chem 271:20192-20197;1996.
50. Milligan JF, Matteucci MD, Martin JC. Current concepts in antisense drug design. J Med Chem 36:1923-1937;1993.
51. Misso NL, Peacock CD, Watkins DN, Thompson PJ. Nitrite generation and antioxidant effects during neutrophil apoptosis. Free Radic Biol Med 28:934-943;2000.
52. Mitra D, Kim J, MacLow C, Karsan A, Laurence J. Role of caspases 1 and 3 and Bcl-2-related molecules in endothelial cell apoptosis associated with thrombotic microangiopathies. Am J Hematol 59:279-287;1998.
53. Moulding DA, Quayle JA, Hart CA, Edwards SW. Mcl-1 expression in human neutrophils: Regulation by cytokines and correlation with cell survival. Blood 92:2495-2502;1998.
54. Nakahara H, Sato EF, Ishisaka R, Kanno T, Yoshioka T, Yasuda T, Inoue M, Utsumi K. Biochemical properties of human oral polymorphonuclear leukocytes. Free Radic Res 28:485-495;1998.
55. Narayanan PK, Ragheb K, Lawler G, Robinson JP. Defects in intracellular oxidative metabolism of neutrophils undergoing apoptosis. J Leukoc Biol 61:481-488;1997.
56. Oishi K, Machida K. Inhibition of neutrophil apoptosis by antioxidants in culture medium. Scand J Immunol 45:21-27;1997.
57. Okada S, Zhang H, Hatano M, Tokuhisa T. A physiologic role of Bcl-xL induced in activated macrophages. J Immunol 160:2590-2596;1998.
58. Okuno S, Shimizu S, Ito T, Nomura M, Hamada E, Tsujimoto Y, Matsuda H. Bcl-2 prevents caspase-independent cell death. J Biol Chem 273:34272-34277;1998.
59. Pahl HL, Burn TC, Tenen DG. Optimization of transient transfection into human myeloid cell lines using a luciferase reporter gene. Exp Hematol 19:1038-1041;1991.
60. Pryor WA, Squadrito GL. The chemistry of peroxynitrite: A product from the reaction of nitric oxide with superoxide. Am J Physiol 268:L699-L722;1995.
61. Rollet LE, Grange MJ, Elbim C, Marquetty C, Gougerot PMA, Pasquier C. Hydroxyl radical as a potential intracellular mediator of polymorphonuclear neutrophil apoptosis. Free Radic Biol Med 24:563-572;1998.
62. Saleh D, Barnes PJ, Giaid A. Increased production of the potent oxidant peroxynitrite in the lungs of patients with idiopathic pulmonary fibrosis. Am J Respir Crit Care Med 155:1763-1769;1997.
63. Sanz C, Benito A, Silva M, Albella B, Richard C, Segovia JC, Insunza A, Beueren JA, Fernandez-Luna JL. The expression of Bcl-x is downregulated during differentiation of human hematopoietic progenitor cells along the granulocyte but not the monocyte/macrophage lineage. Blood 89:3199-3204;1997.
64. Savill JS, Wyllie AH, Henson JE, Walport MJ, Henson PM, Haslett C. Macrophage phagocytosis of aging neutrophils in inflammation. Programmed cell death in the neutrophil leads to its recognition by macrophages. J Clin Invest 83:865-875;1989.
65. Schumacher C. Cellular pharmacology of antisense oligodeoxynucleotides. Methods Enzymol 314:440-454;2000.
66. Simonian PL, Grillot DA, Nunez G. Bcl-2 and Bcl-XL can differentially block chemotherapy-induced cell death. Blood 90:1208-1216;1997.
67. Singer II, Kawka DW, Scott S, Weidner JR, Mumford RA, Riehl TE, Stenson WF. Expression of inducible nitric oxide synthase and nitrotyrosine in colonic epithelium in inflammatory bowel disease. Gastroenterology 111:871-885;1996.
68. Skoog DA. Principles of Instrumental Analysis. Philadelphia, Saunders College Publishing, 5-29;1985.
69. Tajima M, Toguchi M, Kanda Y, Kunii S, Hosaka M, Arakawa H, Maeda M, Satoh K, Asano K, Kochi M, Sakagami H. Role of hydrogen peroxide for cell death induction by sodium 5,6-benzylidene-L-ascorbate. Anticancer Res 18:1697-1702;1998.
70. Takeichi O, Saito I, Okamoto Y, Tsurumachi T, Saito T. Cytokine regulation on the synthesis of nitric oxide in vivo by chronically infected human polymorphonuclear leucocytes. Immunology 93:275-280;1998.
71. Takeuchi T, Nakajima M, Morimoto K. Relationship between the intracellular reactive oxygen species and the induction of oxidative DNA damage in human neutrophil-like cells. Carcinogenesis 17:1543-1548;1996.
72. Tanji MK, Van E-SF, Saito Y, Okazawa M, Klut ME, Hayashi S, Hogg JC. Functional changes in aging polymorphonuclear leukocytes. Circulation 97:91-98;1998.
73. Troy CM, Derossi D, Prochiantz A, Greene LA, Shelanski ML. Downregulation of Cu/Zn superoxide dismutase leads to cell death via the nitric oxide-peroxynitrite pathway. J Neurosci 16:253-261;1996.
74. Virag L, Szabo C. BCL-2 protects peroxynitrite-treated thymocytes from poly(ADP-ribose) synthase (PARS)-independent apoptotic but not from PARS-mediated necrotic cell death. Free Radic Biol Med 29:704-713;2000.
75. Voehringer DW. BCL-2 and glutathione: Alterations in cellular redox state that regulate apoptosis sensitivity. Free Radic Biol Med 27:945-950;1999.
76. 2-induced apoptosis of HL-60 human leukemia cells. J Biol Chem 275:22461-22469;2000.
77. Wang CH, Liu CY, Lin HC, Yu CT, Chung KF, Kuo HP. Increased exhaled nitric oxide in active pulmonary tuberculosis due to inducible NO synthase upregulation in alveolar macrophages. Eur Respir J 11:809-815;1998.
78. Ward C, Wong TH, Murray J, Rahman I, Haslett C, Chilvers ER, Rossi AG. Induction of human neutrophil apoptosis by nitric oxide donors: Evidence for a caspase-dependent, cyclic-GMP-independent, mechanism. Biochem Pharmacol 59:305-314;2000.
79. Watson RW, Redmond HP, Wang JH, Condron C, Bouchier H-D. Neutrophils undergo apoptosis following ingestion of Escherichia coli. J Immunol 156:3986-3992;1996.
80. Weinmann P, Gaehtgens P, Walzog B. Bcl-Xl- and Bax-alpha-mediated regulation of apoptosis of human neutrophils via caspase-3. Blood 93:3106-3115;1999.
81. Wheeler MA, Smith SD, Garcia-Cardena G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. J Clin Invest 99:110-116;1997.
82. 2-induced apoptosis of PC12 cells independent of ceramide formation. Neurol Res 22:556-564;2000.
83. Yanagisawa SF, Sakagami H, Kuribayashi N, Iida M, Sakagami T, Takeda M. Endonuclease activity and induction of DNA fragmentation in human myelogenous leukemic cell lines. Anticancer Res 15:259-265;1995.
84. Zhuang S, Simon G. Peroxynitrite-induced apoptosis involves activation of multiple caspases in HL-60 cells. Am J Physiol Cell Physiol 279:C341-351;2000.