Exogenous nitric oxide enhances neutrophil cell death and DNA fragmentation

American Journal of Respiratory Cell and Molecular Biology

Volumn 18, Issue 3, 1998, Pages 421-428

  Fortenberry, James D ^a,b   Owens, Marilyn L ^a   Brown, Milton R ^a   Atkinson, David ^a   Brown, Lou Ann S ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Children's Healthcare of Atlanta at Egleston   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; FORMYLMETHIONYLLEUCYLPHENYLALANINE; NITRIC OXIDE; OXYGEN; SUPEROXIDE DISMUTASE;

APOPTOSIS; ARTICLE; CELL SURVIVAL; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; IMMUNOLOGY; NEUTROPHIL; TIME;

APOPTOSIS; CELL SURVIVAL; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; N-FORMYLMETHIONINE LEUCYL-PHENYLALANINE; NEUTROPHILS; NITRIC OXIDE; OXYGEN; SUPEROXIDE DISMUTASE; TIME FACTORS;

EID: 0032014833     PISSN: 10441549     EISSN: None     Source Type: Journal    
DOI: 10.1165/ajrcmb.18.3.2875     Document Type: Article

References (32)

1. Zapol, W. M., S. Rimar, N. Gillis, M. Marletta, and C. H. Bosken. 1994. Nitric oxide and the lung. Am. J. Respir. Crit. Care Med. 149:1375-1580.
2. Roberts, J. D., Jr., L. M. Bigatello, G. J. Vlahakes, and W. M. Zapol. 1993. Inhaled nitric oxide in congenital heart disease. Circulation 87:447-453.
3. Kubes, P., M. Suzuki, and D. N. Granger. 1991. Nitric oxide: an endogenous modulator of leukocyte adhesion. Proc. Natl. Acad. Sci. USA 88:4651-4655.
4. Rubanyi, G., E. Ho, E. Cantor, W. Lumma, L. Botelho, and A. Schering. 1991. Cytoprotective function of nitric oxide: inactivation of superoxide radicals from human leukocytes. Biochem. Biophys. Res. Comm. 181:1392-1397.
5. Claney, R. M., J. Leszczynska-Piziak, and S. B. Abramson. 1442. Nitric oxide, an endothelial cell relaxation factor, inhibits neutrophil superoxide anion production via a direct action on the NADPH oxidase. J. Clint. Invest. 90:1116-1121.
6. Weiland, J. E., W. Davis, J. F. Holler, J. Mohammed, P. Dorinsky, and J. Gadek. 1989. Lung neutrophils in the adult respiratory distress syndrome. Am. Rev. Respir. Dis. 133:218-225.
7. Haslett, C. 1992. Resolution of acute inflammation and the role of apoptosis in the tissue late of granulocytes. Clin. Sci. 83:639-648.
8. Wylie, A., J. F. R. Kerr, and A. Currie. 1980. Cell death: the significance of apoptosis. Int. Rev. Cytol. 68:251-306.
9. Searle, J., J. F. R. Kerr, and C. J. Bishop. 1982. Necrosis and apoptosis: distinct modes of cell death with fundamentally different significance. Pathol. Annu. 17:229-259.
10. Savill, J. S., A. H. Wyllie, J. E. Henson, M. J. Walport, P. M. Henson, and C. Haslett. 1989. Macrophage phagocytosis of aging neutrophils in inflammation. J. Clin. Invest. 83:865-875.
11. Cox, G., J. Crossley, and Z. Xing. 1995. Macrophage engulfment of apoptotic neutrophils contributes to the resolution of acute pulmonary inflammation in vivo. Am. J. Respir. Cell Mol. Biol. 12:232-237.
12. Whyte, M. K. B., L. C. Meagher, J. MacDermot, and C. Haslett. 1993. Impairment of function in aging neutrophils is associated with apoptosis. J. Immunol. 150:5124-5134.
13. Albina, J. E., S. Cui, R. B. Mateo, and R. S. Reichner. 1993. Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J. Immunol. 150: 5080-5085.
14. Daher, A. H., J. D. Fortenberry, M. L. Owens, and L. A. Brown. 1997. Effects of exogenous nitric oxide on neutrophil oxidative function and viability. Am. J. Respir. Cell Mol. Biol. 16:407-412.
15. Boyum, A. 1968. Isolation of mononuclear cells and granulocytes from human blood. Scand. J. Clin. Lab. Invest. 21(97):77-78(Suppl).
16. Claney, R. M., M. Y. Miyazak, and P. J. Cannon. 1990. Use of thionitrobenzoic acid to characterize the stability of nitric oxide in aqueous solutions and in porcine aortic endothelial cell suspension. Anal. Biochem. 191:138-143.
17. MacCoubrey, I. C., P. Moore, und R. Haugland. 1991. Quantitative fluorescence measurements of cell viability (cytoxicity) with a multi-well plate scanner. J. Cell. Biol. 111:58a. (Abstr.)
18. Leist, M., F. Gantner, I. Bohlinger, P. Germann, G. Tiegs, and A. Wendel, 1994. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-α requires transcriptional arrest. J. Immunol. 153:1778-1788.
19. Bingisser, R., C. Stey, M. Weller, P. Groscurth, E. Russi, and K. Frei. 1996. Apoptosis in human alveolar macrophages is induced by endotoxin and is modulated by cytokines. Am. J. Respir. Cell Mol. Biol. 15:64-70.
20. Gavrieli, Y., Y. Sherman, and S. Ben-Sasson. 1992. Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J. Cell Biol. 119:493-501.
21. Goreyza, W., J. Gong, and Z. Darzynkiewicz. 1993. Detection of DNA strand breaks in individual apoptotic cells by the in situ terminal deoxynucleotidyl transferase and nick translation assays. Cancer Res. 53:1945-1951.
22. Oberhammer, F., J. W. Wilson, C. Dive, I. D. Morris, J. A. Hickman, A. E. Wakeling, P. R. Walker, and M. Sikorska. 1993. Apoptotic death in epithelial cells: cleavage of DNA to 300 and or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12:3679-3684.
23. Kooy, N., J. Royall, Y. Ye, and J. Beckman. 1995. Peroxynitrite is produced during human adult respiratory distress syndrome. Am. J. Respir. Crit. Care Med. 151:1250-1254.
24. Lin, K., J. Xue, M. Nomen, B. Spur, and P. Wong. 1995. Peroxynitrite-induced apoptosis in IIL-60 cells. J. Biol. Chem. 270:16487-16490.
25. Evan, G., A. Wyllie, C. Gilbert, T. Littlewood, H. Land, M. Brooks, C. Waters, L. Penn, and D. Hancock. 1992. Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119-128.
26. Ogasawara, J., R. Watanabe-Fukunaga, M. Adauchi, A. Matsuzawa, T. Kasugai, Y. Kitamura, N. Itoh, T. Suda, and S. Nagata. 1993. Lethal effect of the anti-Fas antibody in mice. Nature 364:806-809.
27. Kavanagh, B., A. Mouchawar, J. Goldsmith, and R. Pearl. 1994. Effects of inhaled NO and inhibition of endogenous NO synthesis in oxidant-induced acute lung injury. J. Appl. Physiol. 76:1324-1329.
28. Poss, W., O. Timmons, I. Farrukh, J. Hoidal, and J. Michael. 1995. Inhaled nitric oxide prevents the increase in pulmonary vascular permeability caused by hydrogen peroxide. J. Appl. Physiol. 79:886-891.
29. Guiterrez, H., B. Nieves, P. Chumley, A. Rivera, and B. Freeman, 1996. Nitric oxide regulation of superoxide-dependent lung injury: oxidant-protective actions of endogenously produced and exogenously administered nitric oxide. Free Radic. Biol. Med. 21:43-52.
30. Guidot, D., M. Repine, B. Hybertson, and J. Repine. 1995. Inhaled nitric oxide prevents neutrophil-mediated, oxygen radical-dependent leak in isolated rat lungs. Am. J. Phybiol. 269(Lung Cell Mol. Physiol.):12-15.
31. Anderson, D., O. Abassi, J. Fortenberry, J. Koenig, and C. W. Smith. 1993. Abnormalities of LECAM-1- and Mac-1-dependent neutrophil-endothelial cell adhesion in the developing host. In Structure, Function, and Regulation of Molecules Involved in Leukocyte Adhesion. P. Lipsky, K. Rothlein, T. K. Kishimoto, R. Faanes, and C. W. Smith, editors. Springer-Verlag, New York. 337-355.
32. Mulligan, M., J. Hevel, M. Marietta, and P. Ward. 1992. Tissue injury caused by deposition of immune complexes is L-arginine dependent. Proc. Natl. Acad. Sci. USA 88:6338-6342.