-
1
-
-
0033518889
-
CDKN2A variants in a population-based sample of Queensland families with melanoma
-
Aitken J, Welch J, Duffy D, Milligan A, Green A, Martin N, Hayward N (1999) CDKN2A variants in a population-based sample of Queensland families with melanoma. J Natl Cancer Inst 91: 446-452
-
(1999)
J Natl Cancer Inst
, vol.91
, pp. 446-452
-
-
Aitken, J.1
Welch, J.2
Duffy, D.3
Milligan, A.4
Green, A.5
Martin, N.6
Hayward, N.7
-
2
-
-
0036939964
-
The CDKN2A tumour suppressor gene: No mutations detected in patients with melanoma and additional unrelated cancers
-
Alao JP, Mohammed MQ, Retsas S (2002) The CDKN2A tumour suppressor gene: no mutations detected in patients with melanoma and additional unrelated cancers. Melanoma Res 12: 559-563
-
(2002)
Melanoma Res
, vol.12
, pp. 559-563
-
-
Alao, J.P.1
Mohammed, M.Q.2
Retsas, S.3
-
3
-
-
0033552613
-
Regulation of p53 stability
-
Ashcroft M, Vousden KH (1999) Regulation of p53 stability. Oncogene 18: 7637-7643
-
(1999)
Oncogene
, vol.18
, pp. 7637-7643
-
-
Ashcroft, M.1
Vousden, K.H.2
-
4
-
-
0034790609
-
Sporadic multiple primary melanoma cases: CDKN2A germline mutations with a founder effect
-
Auroy S, Avril MF, Chompret A, Pham D, Goldstein AM, Bianchi-Scarra G, Frebourg T, Joly P, Spatz A, Rubino C, Demenais F, Bressac-de Paillerets B (2001) Sporadic multiple primary melanoma cases: CDKN2A germline mutations with a founder effect. Genes Chromosomes Cancer 32: 195-202
-
(2001)
Genes Chromosomes Cancer
, vol.32
, pp. 195-202
-
-
Auroy, S.1
Avril, M.F.2
Chompret, A.3
Pham, D.4
Goldstein, A.M.5
Bianchi-Scarra, G.6
Frebourg, T.7
Joly, P.8
Spatz, A.9
Rubino, C.10
Demenais, F.11
Bressac-de Paillerets, B.12
-
5
-
-
15444350658
-
Germ-line deletion involving the INK4 locus in familial proneness to melanoma and nervous system tumors
-
Bahuau M, Vidaud D, Jenkins RB, Bieche I, Kimmel DW, Assouline B, Smith JS, Alderete B, Cayuela JM, Harpey JP, Caille B, Vidaud M (1998) Germ-line deletion involving the INK4 locus in familial proneness to melanoma and nervous system tumors. Cancer Res 58: 2298-2303
-
(1998)
Cancer Res
, vol.58
, pp. 2298-2303
-
-
Bahuau, M.1
Vidaud, D.2
Jenkins, R.B.3
Bieche, I.4
Kimmel, D.W.5
Assouline, B.6
Smith, J.S.7
Alderete, B.8
Cayuela, J.M.9
Harpey, J.P.10
Caille, B.11
Vidaud, M.12
-
6
-
-
0035422250
-
The melanocortin-1-receptor gene is the major freckle gene
-
Bastiaens M, ter Huurne J, Gruis N, Bergman W, Westendorp R, Vermeer BJ, Bavinck JN (2001) The melanocortin-1-receptor gene is the major freckle gene. Hum Mol Genet 10: 1701-1708
-
(2001)
Hum Mol Genet
, vol.10
, pp. 1701-1708
-
-
Bastiaens, M.1
Ter Huurne, J.2
Gruis, N.3
Bergman, W.4
Westendorp, R.5
Vermeer, B.J.6
Bavinck, J.N.7
-
7
-
-
0034797707
-
Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent Kinase 4 binding
-
Becker TM, Rizos H, Kefford RF, Mann GJ (2001) Functional impairment of melanoma-associated p16(INK4a) mutants in melanoma cells despite retention of cyclin-dependent Kinase 4 binding. Clin Cancer Res 7: 3282-3288
-
(2001)
Clin Cancer Res
, vol.7
, pp. 3282-3288
-
-
Becker, T.M.1
Rizos, H.2
Kefford, R.F.3
Mann, G.J.4
-
8
-
-
0037402496
-
CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono- and bi-allelic 9p21 deletions in childhood acute lymphoblastic leukemia
-
Bertin R, Acquaviva C, Mirebeau D, Guidal-Giroux C, Vilmer E, Cave H (2003) CDKN2A, CDKN2B, and MTAP gene dosage permits precise characterization of mono-and bi-allelic 9p21 deletions in childhood acute lymphoblastic leukemia. Genes Chromosomes Cancer 37: 44-57
-
(2003)
Genes Chromosomes Cancer
, vol.37
, pp. 44-57
-
-
Bertin, R.1
Acquaviva, C.2
Mirebeau, D.3
Guidal-Giroux, C.4
Vilmer, E.5
Cave, H.6
-
9
-
-
18744389747
-
An assessment of the CDKN2A variant Ala148Thr as a nevus/melanoma susceptibility allele
-
Bertram CG, Gaut RM, Barrett JH, Pinney E, Whitaker L, Turner F, Bataille V, Dos Santos Silva I, A JS, Bishop DT, Newton Bishop JA (2002) An assessment of the CDKN2A variant Ala148Thr as a nevus/melanoma susceptibility allele. J Invest Dermatol 119: 961-965
-
(2002)
J Invest Dermatol
, vol.119
, pp. 961-965
-
-
Bertram, C.G.1
Gaut, R.M.2
Barrett, J.H.3
Pinney, E.4
Whitaker, L.5
Turner, F.6
Bataille, V.7
Dos Santos Silva, I.8
A, J.S.9
Bishop, D.T.10
Newton Bishop, J.A.11
-
10
-
-
0034596343
-
High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families
-
Borg A, Sandberg T, Nilsson K, Johannsson O, Klinker M, Masback A, Westerdahl J, Olsson H, Ingvar C (2000) High frequency of multiple melanomas and breast and pancreas carcinomas in CDKN2A mutation-positive melanoma families. J Natl Cancer Inst 92: 1260-1266
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1260-1266
-
-
Borg, A.1
Sandberg, T.2
Nilsson, K.3
Johannsson, O.4
Klinker, M.5
Masback, A.6
Westerdahl, J.7
Olsson, H.8
Ingvar, C.9
-
11
-
-
0034161312
-
Germline CDKN2A mutation implicated in predisposition to multiple myeloma
-
Dilworth D, Liu L, Stewart AK, Berenson JR, Lassam N, Hogg D (2000) Germline CDKN2A mutation implicated in predisposition to multiple myeloma. Blood 95: 1869-1871
-
(2000)
Blood
, vol.95
, pp. 1869-1871
-
-
Dilworth, D.1
Liu, L.2
Stewart, A.K.3
Berenson, J.R.4
Lassam, N.5
Hogg, D.6
-
12
-
-
0031441652
-
Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds
-
Flores JF, Pollock PM, Walker GJ, Glendening JM, Lin AH, Palmer JM, Walters MK, Hayward NK, Fountain JW (1997) Analysis of the CDKN2A, CDKN2B and CDK4 genes in 48 Australian melanoma kindreds. Oncogene 15: 2999-3005
-
(1997)
Oncogene
, vol.15
, pp. 2999-3005
-
-
Flores, J.F.1
Pollock, P.M.2
Walker, G.J.3
Glendening, J.M.4
Lin, A.H.5
Palmer, J.M.6
Walters, M.K.7
Hayward, N.K.8
Fountain, J.W.9
-
13
-
-
0036278859
-
Gene quantification using real-time quantitative PCR: An emerging technology hits the mainstream
-
Ginzinger DG (2002) Gene quantification using real-time quantitative PCR: an emerging technology hits the mainstream. Exp Hematol 30: 503-512
-
(2002)
Exp Hematol
, vol.30
, pp. 503-512
-
-
Ginzinger, D.G.1
-
14
-
-
0036188939
-
Rarity of CDK4 germline mutations in familial melanoma
-
Goldstein AM, Chidambaram A, Halpern A, Holly EA, Guerry ID, Sagebiel R, Elder DE, Tucker MA (2002) Rarity of CDK4 germline mutations in familial melanoma. Melanoma Res 12: 51-55
-
(2002)
Melanoma Res
, vol.12
, pp. 51-55
-
-
Goldstein, A.M.1
Chidambaram, A.2
Halpern, A.3
Holly, E.A.4
Guerry, I.D.5
Sagebiel, R.6
Elder, D.E.7
Tucker, M.A.8
-
15
-
-
0029129816
-
Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations
-
Goldstein AM, Fraser MC, Struewing JP, Hussussian CJ, Ranade K, Zametkin DP, Fontaine LS, Organic SM, Dracopoli NC, Clark Jr WH, Tucker MA (1995) Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations [see comments]. N Engl J Med 333: 970-974
-
(1995)
N Engl J Med
, vol.333
, pp. 970-974
-
-
Goldstein, A.M.1
Fraser, M.C.2
Struewing, J.P.3
Hussussian, C.J.4
Ranade, K.5
Zametkin, D.P.6
Fontaine, L.S.7
Organic, S.M.8
Dracopoli, N.C.9
Clark Jr., W.H.10
Tucker, M.A.11
-
16
-
-
0033569978
-
The genetics of hereditary melanoma and nevi. 1998 update
-
Greene MH (1999) The genetics of hereditary melanoma and nevi. 1998 update. Cancer 86: 2464-2477
-
(1999)
Cancer
, vol.86
, pp. 2464-2477
-
-
Greene, M.H.1
-
17
-
-
0030838776
-
Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: A novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma
-
Guldberg P, Kirkin AF, Gronbaek K, thor Straten P, Ahrenkiel V, Zeuthen J (1997) Complete scanning of the CDK4 gene by denaturing gradient gel electrophoresis: a novel missense mutation but low overall frequency of mutations in sporadic metastatic malignant melanoma. Int J Cancer 72: 780-783
-
(1997)
Int J Cancer
, vol.72
, pp. 780-783
-
-
Guldberg, P.1
Kirkin, A.F.2
Gronbaek, K.3
Thor Straten, P.4
Ahrenkiel, V.5
Zeuthen, J.6
-
18
-
-
6744226360
-
Mutation screening of the CDKN2A promoter in melanoma families
-
Harland M, Holland EA, Ghiorzo P, Mantelli M, Bianchi-Scarra G, Goldstein AM, Tucker MA, Ponder BA, Mann GJ, Bishop DT, Newton Bishop J (2000) Mutation screening of the CDKN2A promoter in melanoma families. Genes Chromosomes Cancer 28: 45-57
-
(2000)
Genes Chromosomes Cancer
, vol.28
, pp. 45-57
-
-
Harland, M.1
Holland, E.A.2
Ghiorzo, P.3
Mantelli, M.4
Bianchi-Scarra, G.5
Goldstein, A.M.6
Tucker, M.A.7
Ponder, B.A.8
Mann, G.J.9
Bishop, D.T.10
Newton Bishop, J.11
-
19
-
-
9844219745
-
Germline mutations of the CDKN2 gene in UK melanoma families
-
Harland M, Meloni R, Gruis N, Pinney E, Brookes S, Spurr NK, Frischauf AM, Bataille V, Peters G, Cuzick J, Selby P, Bishop DT, Bishop JN (1997) Germline mutations of the CDKN2 gene in UK melanoma families. Hum Mol Genet 6: 2061-2067
-
(1997)
Hum Mol Genet
, vol.6
, pp. 2061-2067
-
-
Harland, M.1
Meloni, R.2
Gruis, N.3
Pinney, E.4
Brookes, S.5
Spurr, N.K.6
Frischauf, A.M.7
Bataille, V.8
Peters, G.9
Cuzick, J.10
Selby, P.11
Bishop, D.T.12
Bishop, J.N.13
-
20
-
-
0034671754
-
CDKN2A germ-line mutations in individuals with multiple cutaneous melanomas
-
Hashemi J, Platz A, Ueno T, Stierner U, Ringborg U, Hansson J (2000) CDKN2A germ-line mutations in individuals with multiple cutaneous melanomas. Cancer Res 60: 6864-6867
-
(2000)
Cancer Res
, vol.60
, pp. 6864-6867
-
-
Hashemi, J.1
Platz, A.2
Ueno, T.3
Stierner, U.4
Ringborg, U.5
Hansson, J.6
-
21
-
-
0034230515
-
New developments in melanoma genetics
-
Hayward N (2000) New developments in melanoma genetics. Curr Oncol Rep 2: 300-306
-
(2000)
Curr Oncol Rep
, vol.2
, pp. 300-306
-
-
Hayward, N.1
-
22
-
-
0032784037
-
CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: Effect of family history and multiple primary melanomas
-
Holland EA, Schmid H, Kefford RF, Mann GJ (1999) CDKN2A (P16(INK4a)) and CDK4 mutation analysis in 131 Australian melanoma probands: effect of family history and multiple primary melanomas. Genes Chromosomes Cancer 25: 339-348
-
(1999)
Genes Chromosomes Cancer
, vol.25
, pp. 339-348
-
-
Holland, E.A.1
Schmid, H.2
Kefford, R.F.3
Mann, G.J.4
-
23
-
-
0028100903
-
Germline p16 mutations in familial melanoma
-
Hussussian CJ, Struewing JP, Goldstein AM, Higgins PA, Ally DS, Sheahan MD, Clark Jr WH, Tucker MA, Dracopoli NC (1994) Germline p16 mutations in familial melanoma. Nat Genet 8: 15-21
-
(1994)
Nat Genet
, vol.8
, pp. 15-21
-
-
Hussussian, C.J.1
Struewing, J.P.2
Goldstein, A.M.3
Higgins, P.A.4
Ally, D.S.5
Sheahan, M.D.6
Clark Jr., W.H.7
Tucker, M.A.8
Dracopoli, N.C.9
-
24
-
-
0028085975
-
Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus
-
Kamb A, Shattuck-Eidens D, Eeles R, Liu Q, Gruis NA, Ding W, Hussey C, Tran T, Mild Y, Weaver-Feldhaus J et al. (1994) Analysis of the p16 gene (CDKN2) as a candidate for the chromosome 9p melanoma susceptibility locus. Nat Genet 8: 23-26
-
(1994)
Nat Genet
, vol.8
, pp. 23-26
-
-
Kamb, A.1
Shattuck-Eidens, D.2
Eeles, R.3
Liu, Q.4
Gruis, N.A.5
Ding, W.6
Hussey, C.7
Tran, T.8
Mild, Y.9
Weaver-Feldhaus, J.10
-
25
-
-
0030728468
-
Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF
-
Kamijo T, Zindy F, Roussel MF, Quelle DE, Downing JR, Ashmun RA, Grosveld G, Sherr CJ (1997) Tumor suppression at the mouse INK4a locus mediated by the alternative reading frame product p19ARF. Cell 91: 649-659
-
(1997)
Cell
, vol.91
, pp. 649-659
-
-
Kamijo, T.1
Zindy, F.2
Roussel, M.F.3
Quelle, D.E.4
Downing, J.R.5
Ashmun, R.A.6
Grosveld, G.7
Sherr, C.J.8
-
26
-
-
0034915417
-
Interaction of glutathione S-transferase M1 and T1 genotypes and malignant melanoma
-
Kanetsky PA, Holmes R, Walker A, Najarian D, Swoyer J, Guerry D, Halpern A, Rebbeck TR (2001) Interaction of glutathione S-transferase M1 and T1 genotypes and malignant melanoma. Cancer Epidemiol Biomarkers Prev 10: 509-513
-
(2001)
Cancer Epidemiol Biomarkers Prev
, vol.10
, pp. 509-513
-
-
Kanetsky, P.A.1
Holmes, R.2
Walker, A.3
Najarian, D.4
Swoyer, J.5
Guerry, D.6
Halpern, A.7
Rebbeck, T.R.8
-
27
-
-
0029988115
-
Epidemiology and prognosis of subungual melanoma in 34 Japanese patients
-
Kato T, Suetake T, Sugiyama Y, Tabata N, Tagami H (1996) Epidemiology and prognosis of subungual melanoma in 34 Japanese patients. Br J Dermatol 134: 383-387
-
(1996)
Br J Dermatol
, vol.134
, pp. 383-387
-
-
Kato, T.1
Suetake, T.2
Sugiyama, Y.3
Tabata, N.4
Tagami, H.5
-
28
-
-
0036847390
-
Genetic testing for melanoma
-
Kefford R, Bishop JN, Tucker M, Bressac-de Paillerets B, Bianchi-Scarra G, Bergman W, Goldstein A, Puig S, Mackie R, Elder D, Hansson J, Hayward N, Hogg D, Olsson H (2002) Genetic testing for melanoma. Lancet Oncol 3: 653-654
-
(2002)
Lancet Oncol
, vol.3
, pp. 653-654
-
-
Kefford, R.1
Bishop, J.N.2
Tucker, M.3
Bressac-de Paillerets, B.4
Bianchi-Scarra, G.5
Bergman, W.6
Goldstein, A.7
Puig, S.8
Mackie, R.9
Elder, D.10
Hansson, J.11
Hayward, N.12
Hogg, D.13
Olsson, H.14
-
29
-
-
0032887878
-
Counseling and DNA testing for individuals perceived to be genetically predisposed to melanoma: A consensus statement of the melanoma genetics consortium
-
Kefford RF, Newton Bishop JA, Bergman W, Tucker MA (1999) Counseling and DNA testing for individuals perceived to be genetically predisposed to melanoma: a consensus statement of the melanoma genetics consortium. J Clin Oncol 17: 3245-3251
-
(1999)
J Clin Oncol
, vol.17
, pp. 3245-3251
-
-
Kefford, R.F.1
Newton Bishop, J.A.2
Bergman, W.3
Tucker, M.A.4
-
30
-
-
0035722059
-
Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color
-
Kennedy C, ter Huurne J, Berkhout M, Gruis N, Bastiaens M, Bergman W, Willemze R, Bouwes Bavinck JN (2001) Melanocortin 1 receptor (MC1R) gene variants are associated with an increased risk for cutaneous melanoma which is largely independent of skin type and hair color. J Invest Dermatol 117: 294-300
-
(2001)
J Invest Dermatol
, vol.117
, pp. 294-300
-
-
Kennedy, C.1
Ter Huurne, J.2
Berkhout, M.3
Gruis, N.4
Bastiaens, M.5
Bergman, W.6
Willemze, R.7
Bouwes Bavinck, J.N.8
-
31
-
-
0035923248
-
A single nucleotide polymorphism in the 3'untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare
-
Kumar R, Smeds J, Berggren P, Straume O, Rozell BL, Akslen LA, Hemminki K (2001) A single nucleotide polymorphism in the 3'untranslated region of the CDKN2A gene is common in sporadic primary melanomas but mutations in the CDKN2B, CDKN2C, CDK4 and p53 genes are rare. Int J Cancer 95: 388-393
-
(2001)
Int J Cancer
, vol.95
, pp. 388-393
-
-
Kumar, R.1
Smeds, J.2
Berggren, P.3
Straume, O.4
Rozell, B.L.5
Akslen, L.A.6
Hemminki, K.7
-
32
-
-
0034051469
-
Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations
-
Lal G, Liu L, Hogg D, Lassam NJ, Redston MS, Gallinger S (2000) Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations. Genes Chromosomes Cancer 27: 358-361
-
(2000)
Genes Chromosomes Cancer
, vol.27
, pp. 358-361
-
-
Lal, G.1
Liu, L.2
Hogg, D.3
Lassam, N.J.4
Redston, M.S.5
Gallinger, S.6
-
33
-
-
0032900535
-
Mutation of the CDKN2A 5′ UTR creates an aberrant initiation codon and predisposes to melanoma
-
Liu L, Dilworth D, Gao L, Monzon J, Summers A, Lassam N, Hogg D (1999) Mutation of the CDKN2A 5′ UTR creates an aberrant initiation codon and predisposes to melanoma. Nat Genet 21: 128-132
-
(1999)
Nat Genet
, vol.21
, pp. 128-132
-
-
Liu, L.1
Dilworth, D.2
Gao, L.3
Monzon, J.4
Summers, A.5
Lassam, N.6
Hogg, D.7
-
34
-
-
0031879641
-
CDKN2A germline mutations in UK patients with familial melanoma and multiple primary melanomas
-
MacKie RM, Andrew N, Lanyon WG, Connor JM (1998) CDKN2A germline mutations in UK patients with familial melanoma and multiple primary melanomas. J Invest Dermatol 111: 269-272
-
(1998)
J Invest Dermatol
, vol.111
, pp. 269-272
-
-
MacKie, R.M.1
Andrew, N.2
Lanyon, W.G.3
Connor, J.M.4
-
35
-
-
0024284028
-
A simple salting out procedure for extracting DNA from human nucleated cells
-
Miller SA, Dykes DD, Polesky HF (1988) A simple salting out procedure for extracting DNA from human nucleated cells. Nucleic Acids Res 16: 1215
-
(1988)
Nucleic Acids Res
, vol.16
, pp. 1215
-
-
Miller, S.A.1
Dykes, D.D.2
Polesky, H.F.3
-
36
-
-
0032568258
-
CDKN2A mutations in multiple primary melanomas
-
Monzon J, Liu L, Brill H, Goldstein AM, Tucker MA, From L, McLaughlin J, Hogg D, Lassam NJ (1998) CDKN2A mutations in multiple primary melanomas. N Engl J Med 338: 879-887
-
(1998)
N Engl J Med
, vol.338
, pp. 879-887
-
-
Monzon, J.1
Liu, L.2
Brill, H.3
Goldstein, A.M.4
Tucker, M.A.5
From, L.6
McLaughlin, J.7
Hogg, D.8
Lassam, N.J.9
-
37
-
-
0033910271
-
Melanocortin-1 receptor polymorphisms and risk of melanoma: Is the association explained solely by pigmentation phenotype?
-
Palmer JS, Duffy DL, Box NF, Aitken JF, O'Gorman LE, Green AC, Hayward NK, Martin NG, Sturm RA (2000) Melanocortin-1 receptor polymorphisms and risk of melanoma: is the association explained solely by pigmentation phenotype? Am J Hum Genet 66: 176-186
-
(2000)
Am J Hum Genet
, vol.66
, pp. 176-186
-
-
Palmer, J.S.1
Duffy, D.L.2
Box, N.F.3
Aitken, J.F.4
O'Gorman, L.E.5
Green, A.C.6
Hayward, N.K.7
Martin, N.G.8
Sturm, R.A.9
-
38
-
-
0034025480
-
Melanoma genetics: An update with focus on the CDKN2A(p16)/ARF tumor suppressors
-
Piepkorn M (2000) Melanoma genetics: an update with focus on the CDKN2A(p16)/ARF tumor suppressors. J Am Acad Dermatol 42: 705-722 quiz 723-726
-
(2000)
J Am Acad Dermatol
, vol.42
, pp. 705-722
-
-
Piepkorn, M.1
-
39
-
-
0032549704
-
The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53
-
Pomerantz J, Schreiber-Agus N, Liegeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA (1998) The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92: 713-723
-
(1998)
Cell
, vol.92
, pp. 713-723
-
-
Pomerantz, J.1
Schreiber-Agus, N.2
Liegeois, N.J.3
Silverman, A.4
Alland, L.5
Chin, L.6
Potes, J.7
Chen, K.8
Orlow, I.9
Lee, H.W.10
Cordon-Cardo, C.11
Depinho, R.A.12
-
40
-
-
0028985436
-
p16 gene homozygous deletions in acute lymphoblastic leukemia
-
Quesnel B, Preudhomme C, Philippe N, Vanrumbeke M, Dervite I, Lai JL, Bauters F, Wattel E, Fenaux P (1995) p16 gene homozygous deletions in acute lymphoblastic leukemia. Blood 85: 657-663
-
(1995)
Blood
, vol.85
, pp. 657-663
-
-
Quesnel, B.1
Preudhomme, C.2
Philippe, N.3
Vanrumbeke, M.4
Dervite, I.5
Lai, J.L.6
Bauters, F.7
Wattel, E.8
Fenaux, P.9
-
41
-
-
0035170850
-
A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family
-
Randerson-Moor JA, Harland M, Williams S, Cuthbert-Heavens D, Sheridan E, Aveyard J, Sibley K, Whitaker L, Knowles M, Bishop JN, Bishop DT (2001) A germline deletion of p14(ARF) but not CDKN2A in a melanoma-neural system tumour syndrome family. Hum Mol Genet 10: 55-62
-
(2001)
Hum Mol Genet
, vol.10
, pp. 55-62
-
-
Randerson-Moor, J.A.1
Harland, M.2
Williams, S.3
Cuthbert-Heavens, D.4
Sheridan, E.5
Aveyard, J.6
Sibley, K.7
Whitaker, L.8
Knowles, M.9
Bishop, J.N.10
Bishop, D.T.11
-
42
-
-
0035798659
-
Mutations in the INK4a/ARF melanoma susceptibility locus functionally impair p14ARF
-
Rizos H, Darmanian AP, Holland EA, Mann GJ, Kefford RF (2001a) Mutations in the INK4a/ARF melanoma susceptibility locus functionally impair p14ARF. J Biol Chem 276: 41424-41434
-
(2001)
J Biol Chem
, vol.276
, pp. 41424-41434
-
-
Rizos, H.1
Darmanian, A.P.2
Holland, E.A.3
Mann, G.J.4
Kefford, R.F.5
-
43
-
-
0034660460
-
Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization
-
Rizos H, Darmanian AP, Mann GJ, Kefford RF (2000) Two arginine rich domains in the p14ARF tumour suppressor mediate nucleolar localization. Oncogene 19: 2978-2985
-
(2000)
Oncogene
, vol.19
, pp. 2978-2985
-
-
Rizos, H.1
Darmanian, A.P.2
Mann, G.J.3
Kefford, R.F.4
-
44
-
-
0035817722
-
A melanoma-associated germline mutation in exon 1beta inactivates p14ARF
-
Rizos H, Puig S, Badenas C, Malvehy J, Darmanian AP, Jimenez L, Mila M, Kefford RF (2001b) A melanoma-associated germline mutation in exon 1beta inactivates p14ARF. Oncogene 20: 5543-5547
-
(2001)
Oncogene
, vol.20
, pp. 5543-5547
-
-
Rizos, H.1
Puig, S.2
Badenas, C.3
Malvehy, J.4
Darmanian, A.P.5
Jimenez, L.6
Mila, M.7
Kefford, R.F.8
-
45
-
-
0032541623
-
Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a
-
Russo AA, Tong L, Lee JO, Jeffrey PD, Pavletich NP (1998) Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a. Nature 395: 237-243
-
(1998)
Nature
, vol.395
, pp. 237-243
-
-
Russo, A.A.1
Tong, L.2
Lee, J.O.3
Jeffrey, P.D.4
Pavletich, N.P.5
-
46
-
-
0035040353
-
Recent advances in melanoma research
-
Saida T (2001) Recent advances in melanoma research. J Dermatol Sci 26: 1-13
-
(2001)
J Dermatol Sci
, vol.26
, pp. 1-13
-
-
Saida, T.1
-
47
-
-
0034660892
-
The Pezcoller lecture: Cancer cell cycles revisited
-
Sherr CJ (2000) The Pezcoller lecture: cancer cell cycles revisited. Cancer Res 60: 3689-3695
-
(2000)
Cancer Res
, vol.60
, pp. 3689-3695
-
-
Sherr, C.J.1
-
48
-
-
0344199413
-
Functional evidence for a role of combined CDKN2A (p16-p14(ARF))/CDKN2B (p15) gene inactivation in malignant gliomas
-
Simon M, Koster G, Menon AG, Schramm J (1999) Functional evidence for a role of combined CDKN2A (p16-p14(ARF))/CDKN2B (p15) gene inactivation in malignant gliomas. Acta Neuropathol (Berl) 98: 444-452
-
(1999)
Acta Neuropathol (Berl)
, vol.98
, pp. 444-452
-
-
Simon, M.1
Koster, G.2
Menon, A.G.3
Schramm, J.4
-
49
-
-
6844226190
-
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France
-
The French Familial Melanoma Study Group
-
Soufir N, Avril MF, Chompret A, Demenais F, Bombled J, Spatz A, Stoppa-Lyonnet D, Benard J, Bressac-de Paillerets B (1998a) Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group. Hum Mol Genet 7: 209-216
-
(1998)
Hum Mol Genet
, vol.7
, pp. 209-216
-
-
Soufir, N.1
Avril, M.F.2
Chompret, A.3
Demenais, F.4
Bombled, J.5
Spatz, A.6
Stoppa-Lyonnet, D.7
Benard, J.8
Bressac-de Paillerets, B.9
-
50
-
-
6844226190
-
Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group
-
published erratum appears in Hum Mol Genet 1998 May;7(5):941
-
Soufir N, Avril MF, Chompret A, Demenais F, Bombled J, Spatz A, Stoppa-Lyonnet D, Benard J, Bressac-de Paillerets B (1998b) Prevalence of p16 and CDK4 germline mutations in 48 melanoma-prone families in France. The French Familial Melanoma Study Group [published erratum appears in Hum Mol Genet 1998 May;7(5):941]. Hum Mol Genet 7: 209-216
-
(1998)
Hum Mol Genet
, vol.7
, pp. 209-216
-
-
Soufir, N.1
Avril, M.F.2
Chompret, A.3
Demenais, F.4
Bombled, J.5
Spatz, A.6
Stoppa-Lyonnet, D.7
Benard, J.8
Bressac-de Paillerets, B.9
-
51
-
-
0034669071
-
Association between INK4a-ARF and p53 mutations in skin carcinomas of xeroderma pigmentosum patients
-
Soufir N, Daya-Grosjean L, de La Salmoniere P, Moles JP, Dubertret L, Sarasin A, Basset-Seguin N (2000) Association between INK4a-ARF and p53 mutations in skin carcinomas of xeroderma pigmentosum patients. J Natl Cancer Inst 92: 1841-1847
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 1841-1847
-
-
Soufir, N.1
Daya-Grosjean, L.2
De La Salmoniere, P.3
Moles, J.P.4
Dubertret, L.5
Sarasin, A.6
Basset-Seguin, N.7
-
52
-
-
0032767989
-
Cytochrome P450 CYP2D6 genotypes: Association with hair colour, Breslow thickness and melanocyte stimulating hormone receptor alleles in patients with malignant melanoma
-
Strange RC, Ellison T, Ichii-Jones F, Bath J, Hoban P, Lear JT, Smith AG, Hutchinson PE, Osborne J, Bowers B, Jones PW, Fryer AA (1999) Cytochrome P450 CYP2D6 genotypes: association with hair colour, Breslow thickness and melanocyte stimulating hormone receptor alleles in patients with malignant melanoma. Pharmacogenetics 9: 269-276
-
(1999)
Pharmacogenetics
, vol.9
, pp. 269-276
-
-
Strange, R.C.1
Ellison, T.2
Ichii-Jones, F.3
Bath, J.4
Hoban, P.5
Lear, J.T.6
Smith, A.G.7
Hutchinson, P.E.8
Osborne, J.9
Bowers, B.10
Jones, P.W.11
Fryer, A.A.12
-
53
-
-
0033818195
-
Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma
-
Tsao H, Zhang X, Kwitkiwski K, Finkelstein DM, Sober AJ, Haluska FG (2000) Low prevalence of germline CDKN2A and CDK4 mutations in patients with early-onset melanoma. Arch Dermatol 136: 1118-1122
-
(2000)
Arch Dermatol
, vol.136
, pp. 1118-1122
-
-
Tsao, H.1
Zhang, X.2
Kwitkiwski, K.3
Finkelstein, D.M.4
Sober, A.J.5
Haluska, F.G.6
-
54
-
-
0028018501
-
MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p
-
Ueki K, Rubio MP, Ramesh V, Correa KM, Rutter JL, von Deimling A, Buckler AJ, Gusella JF, Louis DN (1994) MTS1/CDKN2 gene mutations are rare in primary human astrocytomas with allelic loss of chromosome 9p. Hum Mol Genet 3: 1841-1845
-
(1994)
Hum Mol Genet
, vol.3
, pp. 1841-1845
-
-
Ueki, K.1
Rubio, M.P.2
Ramesh, V.3
Correa, K.M.4
Rutter, J.L.5
Von Deimling, A.6
Buckler, A.J.7
Gusella, J.F.8
Louis, D.N.9
-
55
-
-
0028786945
-
Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans
-
Valverde P, Healy E, Jackson I, Rees JL, Thody AJ (1995) Variants of the melanocyte-stimulating hormone receptor gene are associated with red hair and fair skin in humans. Nat Genet 11: 328-330
-
(1995)
Nat Genet
, vol.11
, pp. 328-330
-
-
Valverde, P.1
Healy, E.2
Jackson, I.3
Rees, J.L.4
Thody, A.J.5
-
56
-
-
0028971713
-
Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds
-
Walker GJ, Hussussian CJ, Flores JF, Glendening JM, Haluska FG, Dracopoli NC, Hayward NK, Fountain JW (1995) Mutations of the CDKN2/p16INK4 gene in Australian melanoma kindreds. Hum Mol Genet 4: 1845-1852
-
(1995)
Hum Mol Genet
, vol.4
, pp. 1845-1852
-
-
Walker, G.J.1
Hussussian, C.J.2
Flores, J.F.3
Glendening, J.M.4
Haluska, F.G.5
Dracopoli, N.C.6
Hayward, N.K.7
Fountain, J.W.8
-
57
-
-
0031253976
-
Germline CDKN2A mutations in childhood melanoma
-
Whiteman DC, Milligan A, Welch J, Green AC, Hayward NK (1997) Germline CDKN2A mutations in childhood melanoma. J Natl Cancer Inst 89: 1460
-
(1997)
J Natl Cancer Inst
, vol.89
, pp. 1460
-
-
Whiteman, D.C.1
Milligan, A.2
Welch, J.3
Green, A.C.4
Hayward, N.K.5
-
58
-
-
0034667360
-
A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer
-
Winsey SL, Haldar NA, Marsh HP, Bunce M, Marshall SE, Harris AL, Wojnarowska F, Welsh KI (2000) A variant within the DNA repair gene XRCC3 is associated with the development of melanoma skin cancer. Cancer Res 60: 5612-5616
-
(2000)
Cancer Res
, vol.60
, pp. 5612-5616
-
-
Winsey, S.L.1
Haldar, N.A.2
Marsh, H.P.3
Bunce, M.4
Marshall, S.E.5
Harris, A.L.6
Wojnarowska, F.7
Welsh, K.I.8
-
59
-
-
0034685531
-
Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells
-
Yang CT, You L, Yeh CC, Chang JW, Zhang F, McCormick F, Jablons DM (2000) Adenovirus-mediated p14(ARF) gene transfer in human mesothelioma cells. J Natl Cancer Inst 92: 636-641
-
(2000)
J Natl Cancer Inst
, vol.92
, pp. 636-641
-
-
Yang, C.T.1
You, L.2
Yeh, C.C.3
Chang, J.W.4
Zhang, F.5
McCormick, F.6
Jablons, D.M.7
-
60
-
-
0029836730
-
Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele
-
Yarbrough WG, Aprelikova O, Pei H, Olshan AF, Liu ET (1996) Familial tumor syndrome associated with a germline nonfunctional p16INK4a allele. J Natl Cancer Inst 88: 1489-1491
-
(1996)
J Natl Cancer Inst
, vol.88
, pp. 1489-1491
-
-
Yarbrough, W.G.1
Aprelikova, O.2
Pei, H.3
Olshan, A.F.4
Liu, E.T.5
-
61
-
-
0032509862
-
Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2′,3′-dideoxycytidine- and 1,3-butadiene-induced murine lymphomas
-
Zhuang SM, Schippert A, Haugen-Strano A, Wiseman RW, Soderkvist P (1998) Inactivations of p16INK4a-alpha, p16INK4a-beta and p15INK4b genes in 2′,3′-dideoxycytidine-and 1,3-butadiene-induced murine lymphomas. Oncogene 16: 803-808
-
(1998)
Oncogene
, vol.16
, pp. 803-808
-
-
Zhuang, S.M.1
Schippert, A.2
Haugen-Strano, A.3
Wiseman, R.W.4
Soderkvist, P.5
-
62
-
-
0029664339
-
Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma
-
Zuo L, Weger J, Yang Q, Goldstein AM, Tucker MA, Walker GJ, Hayward N, Dracopoli NC (1996) Germline mutations in the p16INK4a binding domain of CDK4 in familial melanoma. Nat Genet 12: 97-99
-
(1996)
Nat Genet
, vol.12
, pp. 97-99
-
-
Zuo, L.1
Weger, J.2
Yang, Q.3
Goldstein, A.M.4
Tucker, M.A.5
Walker, G.J.6
Hayward, N.7
Dracopoli, N.C.8
|