Hyperglycaemia suppresses the secretion of ghrelin, a novel growth-hormone-releasing peptide: Responses to the intravenous and oral administration of glucose

Clinical Science

Volumn 103, Issue 3, 2002, Pages 325-328

  Nakagawa, Eiichiro ^a   Nagaya, Noritoshi ^a   Okumura, Hiroyuki ^a   Enomoto, Mitsunobu ^a   Oya, Hideo ^a   Ono, Fumiaki ^a   Hosoda, Hiroshi ^a   Kojima, Masayasu ^a   Kangawa, Kenji ^a  

^a NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Ghrelin; Glucose; Growth hormone; Hyperglycaemia.

Indexed keywords

GHRELIN; GLUCOSE; GROWTH HORMONE; PEPTIDE;

ADULT; ARTICLE; BODY FAT; FOOD INTAKE; HORMONE BLOOD LEVEL; HUMAN; HUMAN EXPERIMENT; HYPERGLYCEMIA; MALE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN SECRETION;

EID: 0036714764     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/cs1030325     Document Type: Article

References (11)

1. Ghrelin is a growth-hormone-releasing acylated peptide from stomach
2. Ghrelin induces adiposity in rodents
3. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
4. A role for ghrelin in the central regulation of feeding
5. Ghrelin, an endogenous growth hormone secretagogue, is a novel orexigenic peptide that antagonizes leptin action through the activation of hypothalamic neuropeptide Y/Y1 receptor pathway
6. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
7. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
8. Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycaemia, and leptin administration
9. Studies on the secretion of human-pituitary-growth hormone
10. Effect of food intake on growth hormone level
11. The effect of glucose on growth hormone (GH)-releasing hormone-mediated GH secretion in man