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Volumn 84, Issue 1, 1999, Pages 285-290

Effects of recombinant human insulin-like growth factor I administration on growth hormone (GH) secretion, both spontaneous and stimulated by GH- releasing hormone or hexarelin, a peptidyl GH secretagogue, in humans

Author keywords

[No Author keywords available]

Indexed keywords

GHRH 29; GLUCOSE; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HEXARELIN; INSULIN; SOMATOMEDIN; UNCLASSIFIED DRUG;

EID: 0032905676     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.84.1.285     Document Type: Article
Times cited : (42)

References (46)
  • 1
    • 37049186448 scopus 로고
    • Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary
    • 1. Berelowitz M, Szabo M, Frohman LA, Firestone S, Hintz RL. 1981 Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science. 212:1279-1281.
    • (1981) Science , vol.212 , pp. 1279-1281
    • Berelowitz, M.1    Szabo, M.2    Frohman, L.A.3    Firestone, S.4    Hintz, R.L.5
  • 2
    • 0020552567 scopus 로고
    • Human growth hormone and somatomedin C suppress the spontaneous release of growth hormone in unanesthetized rats
    • 2. Abe H, Molitch ME, Van Wyk JJ, Underwood LE. 1983 Human growth hormone and somatomedin C suppress the spontaneous release of growth hormone in unanesthetized rats. Endocrinology. 113:1319-1324.
    • (1983) Endocrinology , vol.113 , pp. 1319-1324
    • Abe, H.1    Molitch, M.E.2    Van Wyk, J.J.3    Underwood, L.E.4
  • 3
    • 0020693772 scopus 로고
    • Insulin-like growth factors: A role in growth hormone negative feedback and body weight regulation via brain
    • 3. Tannembaum GS, Guyda HJ, Posner BI. 1983 Insulin-like growth factors: a role in growth hormone negative feedback and body weight regulation via brain. Science. 220:77-79.
    • (1983) Science , vol.220 , pp. 77-79
    • Tannembaum, G.S.1    Guyda, H.J.2    Posner, B.I.3
  • 4
    • 0023099782 scopus 로고
    • The growth hormone (GH)-releasing hormone (GHRH)-GH-somatomedin axis: Evidence for rapid inhibition of GHRH-elicited GH release by insulin-like growth factors I and II
    • 4. Ceda GP, Davis RG, Rosenfeld RG, Hoffman AR. 1987 The growth hormone (GH)-releasing hormone (GHRH)-GH-somatomedin axis: evidence for rapid inhibition of GHRH-elicited GH release by insulin-like growth factors I and II. Endocrinology. 120:1658-1662.
    • (1987) Endocrinology , vol.120 , pp. 1658-1662
    • Ceda, G.P.1    Davis, R.G.2    Rosenfeld, R.G.3    Hoffman, A.R.4
  • 5
    • 0023276184 scopus 로고
    • Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults
    • 5. Guler HP, Zapf J, Froesch ER. 1987 Short-term metabolic effects of recombinant human insulin-like growth factor I in healthy adults. N Engl J Med. 317:137-140.
    • (1987) N Engl J Med. , vol.317 , pp. 137-140
    • Guler, H.P.1    Zapf, J.2    Froesch, E.R.3
  • 6
    • 1842279310 scopus 로고
    • Effect of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects
    • 6. Guler HP, Schmid C, Zapf J, Froesch ER. 1989 Effect of recombinant insulin-like growth factor I on insulin secretion and renal function in normal human subjects. Proc Natl Acad Sci USA. 86:2868-2872.
    • (1989) Proc Natl Acad Sci USA , vol.86 , pp. 2868-2872
    • Guler, H.P.1    Schmid, C.2    Zapf, J.3    Froesch, E.R.4
  • 7
    • 0025837933 scopus 로고
    • Biochemical and hormonal changes induced by one week of administration of rhIGF-I to patients with Laron type dwarfism
    • 7. Laron Z, Klinger B, Jensen LT, Erster B. 1991 Biochemical and hormonal changes induced by one week of administration of rhIGF-I to patients with Laron type dwarfism. Clin Endocrinol (Oxf). 35;145-150.
    • (1991) Clin Endocrinol (Oxf) , vol.35 , pp. 145-150
    • Laron, Z.1    Klinger, B.2    Jensen, L.T.3    Erster, B.4
  • 8
    • 0025782707 scopus 로고
    • Intracerebral administration of insulin-like growth factor I decreases circulating growth hormone levels in the fetal pig
    • 8. Spencer GSG, Macdonald AA, Buttle HL, Moore LG, Carlyle SS. 1991 Intracerebral administration of insulin-like growth factor I decreases circulating growth hormone levels in the fetal pig. Acta Endocrinol (Copenh). 124:563-568.
    • (1991) Acta Endocrinol (Copenh) , vol.124 , pp. 563-568
    • Spencer, G.S.G.1    Macdonald, A.A.2    Buttle, H.L.3    Moore, L.G.4    Carlyle, S.S.5
  • 9
    • 0027247493 scopus 로고
    • A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans
    • 9. Hartman ML, Clayton PE, Johnson ML, et al. 1993 A low dose euglycemic infusion of recombinant human insulin-like growth factor I rapidly suppresses fasting-enhanced pulsatile growth hormone secretion in humans. J Clin Invest. 91:2453-2462.
    • (1993) J Clin Invest. , vol.91 , pp. 2453-2462
    • Hartman, M.L.1    Clayton, P.E.2    Johnson, M.L.3
  • 10
    • 0028928690 scopus 로고
    • IGF feedback effects on growth hormone secretion in ewes: Evidence for action at the pituitary but not the hypothalamic level
    • 10. Fletcher TP, Thomas GB, Dunshea FR, Moore LG, Clarke IJ. 1995 IGF feedback effects on growth hormone secretion in ewes: evidence for action at the pituitary but not the hypothalamic level. J Endocrinol. 144:323-331.
    • (1995) J Endocrinol. , vol.144 , pp. 323-331
    • Fletcher, T.P.1    Thomas, G.B.2    Dunshea, F.R.3    Moore, L.G.4    Clarke, I.J.5
  • 11
    • 0030953395 scopus 로고    scopus 로고
    • Effect of aging on the sensitivity of growth hormone secretion to insulin-like growth factor-I negative feedback
    • 11. Chapman IM, Hartman ML, Pezzoli SS, et al. 1997 Effect of aging on the sensitivity of growth hormone secretion to insulin-like growth factor-I negative feedback. J Clin Endocrinol Metab. 82:2996-3004.
    • (1997) J Clin Endocrinol Metab. , vol.82 , pp. 2996-3004
    • Chapman, I.M.1    Hartman, M.L.2    Pezzoli, S.S.3
  • 12
    • 0022525408 scopus 로고
    • Identification of binding sites for an insulin-like growth factor (IGF-I) in the median eminence of the rat brain by quantitative autoradiography
    • 12. Bohannon NJ, Figlewicz DP, Corp ES, Wilcox J, Porte D, Baskin DG. 1986 Identification of binding sites for an insulin-like growth factor (IGF-I) in the median eminence of the rat brain by quantitative autoradiography. Endocrinology. 119:943-945.
    • (1986) Endocrinology , vol.119 , pp. 943-945
    • Bohannon, N.J.1    Figlewicz, D.P.2    Corp, E.S.3    Wilcox, J.4    Porte, D.5    Baskin, D.G.6
  • 13
    • 0022631161 scopus 로고
    • Insulin-like growth factor I action on rat anterior pituitary cells: Suppression of growth hormone secretion and messenger ribonucleic acid levels
    • 13. Yamashita S, Melmed S. 1986 Insulin-like growth factor I action on rat anterior pituitary cells: suppression of growth hormone secretion and messenger ribonucleic acid levels. Endocrinology. 118:176-182.
    • (1986) Endocrinology. , vol.118 , pp. 176-182
    • Yamashita, S.1    Melmed, S.2
  • 14
    • 0031792737 scopus 로고    scopus 로고
    • Human fetal pituitary expresses functional growth hormone-releasing peptide receptors
    • 14. Shimon I, Yan X, Melmed S. 1998 Human fetal pituitary expresses functional growth hormone-releasing peptide receptors. J Clin Endocrinol Metab. 83:1744-1748.
    • (1998) J Clin Endocrinol Metab. , vol.83 , pp. 1744-1748
    • Shimon, I.1    Yan, X.2    Melmed, S.3
  • 15
    • 0027250099 scopus 로고
    • Differential effects of central and peripheral administration of GH and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats
    • 15. Sato M, Frohman LA. 1993 Differential effects of central and peripheral administration of GH and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats. Endocrinology. 133:793-799.
    • (1993) Endocrinology , vol.133 , pp. 793-799
    • Sato, M.1    Frohman, L.A.2
  • 16
    • 0022474914 scopus 로고
    • In vitro release of growth hormone-releasing factor from rat hypothalamus: Effect of insulin-like growth factor-I
    • 16. Shibasaki T, Yamauchi N, Hotta M, et al. 1986 In vitro release of growth hormone-releasing factor from rat hypothalamus: effect of insulin-like growth factor-I. Regul Pept. 15:47-51.
    • (1986) Regul Pept. , vol.15 , pp. 47-51
    • Shibasaki, T.1    Yamauchi, N.2    Hotta, M.3
  • 17
    • 0026731175 scopus 로고
    • Synergistic interaction between insulin-like growth factors I and II in central regulation of pulsatile growth hormone secretion
    • 17. Harel Z, Tannembaum GS. 1992 Synergistic interaction between insulin-like growth factors I and II in central regulation of pulsatile growth hormone secretion. Endocrinology. 131:758-764.
    • (1992) Endocrinology , vol.131 , pp. 758-764
    • Harel, Z.1    Tannembaum, G.S.2
  • 18
    • 0029774282 scopus 로고    scopus 로고
    • Acquired growth hormone resistance in catabolic states
    • 18. Jenkins RC, Ross RJM. 1996 Acquired growth hormone resistance in catabolic states. Baillieres Clin Endocrinol Metab. 10;3:411-419.
    • (1996) Baillieres Clin Endocrinol Metab. , vol.10 , Issue.3 , pp. 411-419
    • Jenkins, R.C.1    Ross, R.J.M.2
  • 19
    • 0028127946 scopus 로고
    • Nutritional regulation of the insulin-like growth factors
    • 19. Thissen J, Ketelslegers JM, Underwood LE. 1994 Nutritional regulation of the insulin-like growth factors. Endocr Rev. 15:80-101.
    • (1994) Endocr Rev. , vol.15 , pp. 80-101
    • Thissen, J.1    Ketelslegers, J.M.2    Underwood, L.E.3
  • 20
    • 0027272980 scopus 로고
    • Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome
    • 20. Vaccarello MA, Diamond FB, Guevara-Aguirre J, et al. 1993 Hormonal and metabolic effects and pharmacokinetics of recombinant insulin-like growth factor-I in growth hormone receptor deficiency/Laron syndrome. J Clin Endocrinol Metab. 77:273-280.
    • (1993) J Clin Endocrinol Metab. , vol.77 , pp. 273-280
    • Vaccarello, M.A.1    Diamond, F.B.2    Guevara-Aguirre, J.3
  • 21
    • 0028229243 scopus 로고
    • The effects of recombinant human insulin-like growth factor I on growth hormone secretion in adolescents with insulin-dependent diabetes mellitus
    • 21. Cheetham TD, Clayton K, Taylor AM, Holly J, Matthews DR, Dunger DB. 1994 The effects of recombinant human insulin-like growth factor I on growth hormone secretion in adolescents with insulin-dependent diabetes mellitus. Clin Endocrinol (Oxf). 40:515-522.
    • (1994) Clin Endocrinol (Oxf) , vol.40 , pp. 515-522
    • Cheetham, T.D.1    Clayton, K.2    Taylor, A.M.3    Holly, J.4    Matthews, D.R.5    Dunger, D.B.6
  • 22
    • 0028596961 scopus 로고
    • The effect of recombinant IGF-I on anterior pituitary function in healthy volunteers
    • 22. Trainer PJ, Holly J, Medbak S, Rees LH, Besser GM. 1994 The effect of recombinant IGF-I on anterior pituitary function in healthy volunteers. Clin Endocrinol (Oxf). 41:801-807.
    • (1994) Clin Endocrinol (Oxf) , vol.41 , pp. 801-807
    • Trainer, P.J.1    Holly, J.2    Medbak, S.3    Rees, L.H.4    Besser, G.M.5
  • 24
    • 0023808322 scopus 로고
    • Effect of acute administration of insulin-like growth factor I in patients with Laron-type dwarfism
    • 24. Laron Z, Erster B, Klinger B, Anin S. 1988 Effect of acute administration of insulin-like growth factor I in patients with Laron-type dwarfism. Lancet 11:1171-1172.
    • (1988) Lancet , vol.11 , pp. 1171-1172
    • Laron, Z.1    Erster, B.2    Klinger, B.3    Anin, S.4
  • 27
    • 9844230970 scopus 로고    scopus 로고
    • Peptidomimetic regulation of growth hormone secretion
    • 27. Smith R, Van der Ploeg L, Howard A, et al. 1997 Peptidomimetic regulation of growth hormone secretion. Endocr Rev. 18:621-645.
    • (1997) Endocr Rev. , vol.18 , pp. 621-645
    • Smith, R.1    Van Der Ploeg, L.2    Howard, A.3
  • 28
    • 0028968462 scopus 로고
    • Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamo-pituitary disconnection: Evidence that GHRP-6 main action is exerted at the hypothalamic level
    • 28. Popovic V, Damjanovic S, Micic D, Djurovic M, Dieguez C, Casanueva FF. 1995 Blocked growth hormone-releasing peptide (GHRP-6)-induced GH secretion and absence of the synergic action of GHRP-6 plus GH-releasing hormone in patients with hypothalamo-pituitary disconnection: evidence that GHRP-6 main action is exerted at the hypothalamic level. J Clin Endocrinol Metab. 80:942-947.
    • (1995) J Clin Endocrinol Metab. , vol.80 , pp. 942-947
    • Popovic, V.1    Damjanovic, S.2    Micic, D.3    Djurovic, M.4    Dieguez, C.5    Casanueva, F.F.6
  • 29
    • 17644439585 scopus 로고    scopus 로고
    • Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland
    • 29. Muccioli G, Ghè C, Ghigo MC, et al. 1998 Specific receptors for synthetic GH secretagogues in the human brain and pituitary gland. J Endocrinol. 157:99-106.
    • (1998) J Endocrinol. , vol.157 , pp. 99-106
    • Muccioli, G.1    Ghè, C.2    Ghigo, M.C.3
  • 30
    • 85011457887 scopus 로고    scopus 로고
    • Identification of a pituitary GHRP receptor subtype by the fotoaffinity labeling approach using I125 p-benzoyl-phenylalanine hexarelin derivative
    • 30. Ong H, McNicoll N, Escher F, et al. 1998 Identification of a pituitary GHRP receptor subtype by the fotoaffinity labeling approach using I125 p-benzoyl-phenylalanine hexarelin derivative. Endocrinology. 139:432-435.
    • (1998) Endocrinology , vol.139 , pp. 432-435
    • Ong, H.1    McNicoll, N.2    Escher, F.3
  • 31
    • 0028301613 scopus 로고
    • Effects of repeated subcutaneous administration of recombinant human insulin-like growth factor I in adults with growth hormone deficiency
    • 31 Thoren MC, Wivall-Helleryd IL, Blum WF, Hall KE. 1994 Effects of repeated subcutaneous administration of recombinant human insulin-like growth factor I in adults with growth hormone deficiency. Eur J Endocrinol. 131:33-40.
    • (1994) Eur J Endocrinol. , vol.131 , pp. 33-40
    • Thoren, M.C.1    Wivall-Helleryd, I.L.2    Blum, W.F.3    Hall, K.E.4
  • 32
    • 38149148193 scopus 로고
    • Growth hormone binding protein and growth hormone sensitivity
    • 32. Baumann G. 1994 Growth hormone binding protein and growth hormone sensitivity. Endocrinol Metab Clin North Am. [Suppl A] 1:21-25.
    • (1994) Endocrinol Metab Clin North Am. , vol.1 , Issue.SUPPL. A , pp. 21-25
    • Baumann, G.1
  • 33
    • 0013514626 scopus 로고
    • Mechanisms and pathways of gonadal steroid modulation of growth hormone secretion
    • 33. Wehrenberg WB, Giustina A. 1992 Mechanisms and pathways of gonadal steroid modulation of growth hormone secretion. Endocr Rev. 13:281-298.
    • (1992) Endocr Rev. , vol.13 , pp. 281-298
    • Wehrenberg, W.B.1    Giustina, A.2
  • 34
    • 0023853012 scopus 로고
    • Growth regulation and its alteration in disease states
    • 34. Dieguez C, Page MD, Scanlon MF. 1988 Growth regulation and its alteration in disease states. Clin Endocrinol (Oxf). 28:109-143.
    • (1988) Clin Endocrinol (Oxf) , vol.28 , pp. 109-143
    • Dieguez, C.1    Page, M.D.2    Scanlon, M.F.3
  • 35
    • 0029737991 scopus 로고    scopus 로고
    • New modalities for understanding dynamic regulation of the somatotropic (GH) axis: Explication of gender differences in GH neuroregulation in the human
    • 35. Veldhuis JD. 1996 New modalities for understanding dynamic regulation of the somatotropic (GH) axis: explication of gender differences in GH neuroregulation in the human. J Pediatr Endocrinol Metab. 9:237-253.
    • (1996) J Pediatr Endocrinol Metab. , vol.9 , pp. 237-253
    • Veldhuis, J.D.1
  • 36
    • 0021828930 scopus 로고
    • Independent effects of growth hormone-releasing factor on growth hormone release and gene transcription
    • 36. Barinaga M, Bilezikjian LM, Vale WW, Rosenfeld MG, Evans RM. 1985 Independent effects of growth hormone-releasing factor on growth hormone release and gene transcription. Nature. 314:279-281.
    • (1985) Nature , vol.314 , pp. 279-281
    • Barinaga, M.1    Bilezikjian, L.M.2    Vale, W.W.3    Rosenfeld, M.G.4    Evans, R.M.5
  • 37
    • 0030913412 scopus 로고    scopus 로고
    • Effects of GH and IGF-I administration on GHRH and somatostatin mRNA levels: A study on ad libitum fed and starved adult male rats
    • 37. Ghigo MC, Torsello A, Grilli R, et al. 1997 Effects of GH and IGF-I administration on GHRH and somatostatin mRNA levels: a study on ad libitum fed and starved adult male rats. J Endocrinol Invest. 20:144-150.
    • (1997) J Endocrinol Invest. , vol.20 , pp. 144-150
    • Ghigo, M.C.1    Torsello, A.2    Grilli, R.3
  • 39
    • 0026607276 scopus 로고
    • Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors
    • 39. Goth MI, Lyons CE, Canny BY, Thorner MO. 1992 Pituitary adenylate cyclase activating polypeptide, growth hormone (GH)-releasing peptide and GH-releasing hormone stimulate GH release through distinct pituitary receptors. Endocrinology. 130:939-944.
    • (1992) Endocrinology , vol.130 , pp. 939-944
    • Goth, M.I.1    Lyons, C.E.2    Canny, B.Y.3    Thorner, M.O.4
  • 40
    • 0028851410 scopus 로고
    • Modulation of growth hormone-releasing activity of hexarelin in man
    • 40. Arvat E, Gianotti L, Grottoli S, et al. 1995 Modulation of growth hormone-releasing activity of hexarelin in man. Neuroendocrinology. 61:51-56.
    • (1995) Neuroendocrinology , vol.61 , pp. 51-56
    • Arvat, E.1    Gianotti, L.2    Grottoli, S.3
  • 41
    • 0028841517 scopus 로고
    • Hexarelin induced growth hormone release is influenced by exogenous growth hormone
    • 41. Massoud AF, Hindmarsh PC, Brook CGD. 1995 Hexarelin induced growth hormone release is influenced by exogenous growth hormone. Clin Endocrinol (Oxf). 43:617-621.
    • (1995) Clin Endocrinol (Oxf) , vol.43 , pp. 617-621
    • Massoud, A.F.1    Hindmarsh, P.C.2    Brook, C.G.D.3
  • 42
    • 0028026646 scopus 로고
    • Growth hormone (GH)-releasing hormone secretion is stimulated by a new GH-releasing hexapeptide in sheep
    • 42. Guillame V, Magnan E, Cataldi M, et al. 1994 Growth hormone (GH)-releasing hormone secretion is stimulated by a new GH-releasing hexapeptide in sheep. Endocrinology. 135:1073-1076.
    • (1994) Endocrinology , vol.135 , pp. 1073-1076
    • Guillame, V.1    Magnan, E.2    Cataldi, M.3
  • 43
    • 0031732737 scopus 로고    scopus 로고
    • Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation
    • 43. Pandya N, DeMott-Friberg R, Bowers CY, Barkan AL, Jaffe CA. 1998 Growth hormone (GH)-releasing peptide-6 requires endogenous hypothalamic GH-releasing hormone for maximal GH stimulation. J Clin Endocrinol Metab. 83:1186-1189.
    • (1998) J Clin Endocrinol Metab. , vol.83 , pp. 1186-1189
    • Pandya, N.1    DeMott-Friberg, R.2    Bowers, C.Y.3    Barkan, A.L.4    Jaffe, C.A.5
  • 44
    • 0019218728 scopus 로고
    • Evidence for autoregulation of growth hormone secretion via the central nervous system
    • 44. Tannembaum GS. 1980 Evidence for autoregulation of growth hormone secretion via the central nervous system. Endocrinology. 107:2117-2120.
    • (1980) Endocrinology , vol.107 , pp. 2117-2120
    • Tannembaum, G.S.1
  • 45
    • 0027944106 scopus 로고
    • Effects of acute and repeated intravenous administration of L-692,585, a novel nonpeptidyl growth hormone secretagogue, on plasma growth hormone, IGF-I, ACTH, cortisol, prolactin, insulin and thyroxine levels in beagles
    • 45. Jacks T, Hickey G, Judith F, et al. 1994 Effects of acute and repeated intravenous administration of L-692,585, a novel nonpeptidyl growth hormone secretagogue, on plasma growth hormone, IGF-I, ACTH, cortisol, prolactin, insulin and thyroxine levels in beagles. J Endocrinol. 143:399-406.
    • (1994) J Endocrinol. , vol.143 , pp. 399-406
    • Jacks, T.1    Hickey, G.2    Judith, F.3
  • 46
    • 0030732108 scopus 로고    scopus 로고
    • Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat
    • 46. Bennet PA, Thomas GB, Howard AD, et al. 1997 Hypothalamic growth hormone secretagogue-receptor (GHS-R) expression is regulated by growth hormone in the rat. Endocrinology. 138:4552-4557.
    • (1997) Endocrinology , vol.138 , pp. 4552-4557
    • Bennet, P.A.1    Thomas, G.B.2    Howard, A.D.3


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