Effect of Therapeutic Doses of Ionising Radiation on the Somatomammotroph Pituitary Cell Line, GH3

Endocrine Journal

Volumn 50, Issue 5, 2003, Pages 621-628

  Mareková, Martina ^a   Čáp, Jan ^a   Vokurková, Doris ^b   Vávrová, Jiřina ^c   Cerman, Jaroslav ^a  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL HRADEC KRALOVE   (Czech Republic)

^c University Hospital ^*

Author keywords

Apoptosis; Ionising radiation; Pituitary cells GH3

Indexed keywords

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE G2 PHASE; CELL DEATH; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL STRAIN GH3; CONTROLLED STUDY; GAMMA KNIFE; GAMMA RADIATION; HYPOPHYSIS ADENOMA; HYPOPHYSIS CELL; IONIZING RADIATION; METAPHASE; NONHUMAN; RADIATION DOSE; RAT;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL DIVISION; CELL LINE, TUMOR; DOSE-RESPONSE RELATIONSHIP, RADIATION; GROWTH HORMONE; PITUITARY GLAND, ANTERIOR; PROLACTIN; RATS;

EID: 10744222808     PISSN: 09188959     EISSN: None     Source Type: Journal    
DOI: 10.1507/endocrj.50.621     Document Type: Article

References (32)

1. Melmed S (1990) Acromegaly. N Engl J Med 322: 966-977.
2. Melmed S, Jackson I, Kleinberg D, Klibanski A (1998) Current treatment guidelines for acromegaly. J Clin Endocrinol Metab 83: 2646-2652.
3. Stewart P (2000) Current therapy for Acromegaly. Trends Endocrinol Metab 11: 128-132.
4. Kristof RA, Schramm J, Redel L, Neuloh G, Wichers M, Klingmuller D (2002) Endocrinological outcome following first time transsphenoidal surgery for GH-, ACTH-, and PRL-secreting pituitary adenomas. Acta Neurochir 144: 555-561.
5. Ross DA, Wilson CB (1988) Results of transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma in a series of 214 patients. J Neurosurg 68: 854-867.
6. Freda PU (2002) Somatostatin analogs in acromegaly. J Clin Endocrinol Metab 87: 3013-3018.
7. Lamberts SW (1988) The role of somatostatin in the regulation of anterior pituitary hormone secretion and the use of its analogs in the treatment of human pituitary tumors. Endocr Rev 9: 417-436.
8. Newman CB, Melmed S, George A, Torigian D, Duhaney M, Snyder P, Young W, Klibanski A, Molitch ME, Gagel R, Sheeler L, Cook D, Malarkey W, Jackson I, Vance ML, Barkan A, Frohman L, Kleinberg DL (1998) Octreotide as primary therapy for acromegaly. J Clin Endocrinol Metab 83: 3034-3040.
9. Becker G, Kocher M, Kortmann RD, Paulsen F, Jeremic B, Muller RP, Bamberg M (2002) Radiation therapy in the multimodal treatment approach of pituitary adenoma. Strahlenther Onkol 178: 173-186.
10. Biermasz NR, Van Dulken H, Roelfsema F (2000) Long-term follow-up results of postoperative radiotherapy in 36 patients with acromegaly. J Clin Endocrinol Metab 85: 2476-2482.
11. Vladyka V, Liščák R, Šimonová G, Urgošik D, Chytka T, Vymazal J, Novotný J, Marek J, Hána V (2000) Gamma Knife (GK) radiosurgery for pituitary adenomas: evaluation of a series of 163 patients. J Radiosurgery 3: 113-131.
12. Landolt AM, Haller D, Lomax N, Scheib S, Schubiger O, Siegfried J, Wellis G (1998) Stereotactic radiosurgery for recurrent surgically treated acromegaly: comparison with fractionated radiotherapy. J Neurosurg 88: 1002-1008.
13. Khanna KK, Jackson SP (2001) DNA double-strand breaks: signaling, repair and the cancer connection. Nature Genetics 27: 247-254.
14. Szkanderová S, Vávrová J, Mareková M (2001) Changes of expression of p53 and p21 at cell line MOLT-4 after irradiation. Acta Radiobiologica 1: 82-84 (in Czech).
15. Hengartner MO (2000) The biochemistry of apoptosis. Nature 407: 770-776.
16. Belka C, Rudner J, Wesselborg S, Stepczynska A (2000) Differential role of caspase-8 and BID activation during radiation- and CD95-induced apoptosis. Oncogene 19: 1181-1190.
17. Aldridge DR, Radford IR (1998) Explaining differences in sensitivity to killing by ionizing radiation between human lymphoid cell lines. Cancer Res 58: 2817-2824.
18. Mareková M, Vávrová J, Vokurková D (2003) Monitoring of premitotic and postmitotic apoptosis in gamma irradiated HL-60 cells by the mitochondrial membrane protein-specific monoclonal antibody APO2.7. Gen Physiol Biophys (in press).
19. Vávrová J, Mareková M, Vokurková D (2001) Radiation-induced apoptosis and cell cycle progression in TP53-deficient human leukemia cell line HL-60. Neoplasma 48: 26-33.
20. Hopcia KL, McCarey ZL, Sylvester FC, Held KD (1996) Radiation-induced apoptosis in HL-60 cells: Oxygen effect, relationship between apoptosis and loss of clonogenity, and dependence of time to apoptosis on radiation dose. Radiat Res 145: 315-323.
21. Dynlacht JR, Eatles M, Herthorn J, Roberts ZV, Howard EW, Sono JD, Sparling D, Story MD (1999) Degradation of the nuclear matrix is a common element during radiation-induced apoptosis and necrosis. Radiat Res 152: 590-603.
22. Vávrová J, Mareková M, Szkanderová S, Vokrurková D, Stulik J, Bláha M, Jebavý L, Filip S (2002) Ionizing radiation-induced apoptosis and degradation of the nuclear matrix in hematopoiteic cells. In: Biophysics of the Genome and Its Interactions. Brno: MU, 86-91.
23. Nakano H, Kohara M, Shinohara K (2001) Evaluation of the relative contribution of p53-mediated pathway in X-ray-induced apoptosis in human leukemic MOLT-4 cells by transfection with a mutant p53 gene at different expression levels. Cell Tissue Res 306: 101-106.
24. Radford IR (2002) Model for the initiation of ionizing radiation-induced apoptosis in lymphoid cells by complex DNA double-strand breaks. Int J Radiat Biol 78: 467-474.
25. Yin D, Tamaki N, Kokrunai T, Yasuo K, Yonezawa K (1999) Bromocriptine-induced apoptosis in pituitary adenoma cells: relationship to p53 and bcl-2 expression. J Clin Neurosci 6: 326-331.
26. Kanasaki H, Fukunaga K, Takahashi K, Miyazaki K, Miyamoto E (2000) Involvement of p38 mitogen-activated protein kinase activation in bromocriptine-induced apoptosis in rat pituitary GH3 cells. Biol Reprod 62: 1486-1494.
27. Yoshinaga N, Yasuda Y, Murayama T, Nomura Y (2000) Possible involvement of cytosolic phospholipase A(2) in cell death induced by 1-methyl-4-phenylpyridinium ion, a dopaminergic neurotoxin, in GH3 cells. Brain Res 855: 244-251.
28. Tergau F, Weichert J, Quentin I, Opitz R, von Zezschwitz C, Marwitz J, Ritz V, Steinfelder HJ (1997) Inhibitors of ser/thr phosphatases 1 and 2A induce apoptosis in pituitary GH3 cells. Naunyn Schmiedebergs Arch Pharmacol 356: 8-16.
29. Ritz V, Marwitz J, Richter E, Ziemann C, Quentin I, Steinfelder HJ (1997) Characterization of two pituitary GH3 cell sublines partially resistant to apoptosis induction by okadaic acid. Biochem Pharmacol 54: 967-971.
30. Zou H, Henzel WJ, Liu X, Lutschg A, Wang X (2000) Apaf-1, a human protein homologous to C.elegans CED-4, participates in cytochrome c-dependent activation of caspase-3. Cell 90: 405-413.
31. Woloschak M, Yu A, Xiao J (1996) Molecular and cellular responses to DNA damage in murine pituitary adenoma cell line. Mol Cell Endocrinol 119: 61-68.
32. Mareková M (2001) Hormonal and pharmacological treatement of pituitary adenomas: apoptosis in model tissue cultures. Disertation work, Faculty of Medicine in Hradec Králové, Charles University in Prague, Czech Republic.