메뉴 건너뛰기




Volumn 28, Issue 1, 2005, Pages 118-127

Neuroprotective effect of the immune system in a mouse model of severe dysmyelinating hereditary neuropathy: Enhanced axonal degeneration following disruption of the RAG-1 gene

Author keywords

[No Author keywords available]

Indexed keywords

MYELIN; RAG1 PROTEIN;

EID: 10644221249     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mcn.2004.09.001     Document Type: Article
Times cited : (32)

References (49)
  • 1
    • 0030979840 scopus 로고    scopus 로고
    • Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32
    • P. Anzini, D.H.H. Neuberg, M. Schachner, E. Nelles, K. Willecke, J. Zielasek, K.V. Toyka, U. Suter, and R. Martini Structural abnormalities and deficient maintenance of peripheral nerve myelin in mice lacking the gap junction protein connexin 32 J. Neurosci. 17 1997 4545 4551
    • (1997) J. Neurosci. , vol.17 , pp. 4545-4551
    • Anzini, P.1    Neuberg, D.H.H.2    Schachner, M.3    Nelles, E.4    Willecke, K.5    Zielasek, J.6    Toyka, K.V.7    Suter, U.8    Martini, R.9
  • 2
    • 0032563605 scopus 로고    scopus 로고
    • Functional gap junctions in the Schwann cell myelin sheath
    • R.J. Balice-Gordon, L.J. Bone, and S.S. Scherer Functional gap junctions in the Schwann cell myelin sheath J. Cell Biol. 142 1998 1095 1104
    • (1998) J. Cell Biol. , vol.142 , pp. 1095-1104
    • Balice-Gordon, R.J.1    Bone, L.J.2    Scherer, S.S.3
  • 3
    • 0023317628 scopus 로고
    • Cellular localization of nerve growth factor synthesis by in situ hybridization
    • C.E. Bandtlow, R. Heumann, M.E. Schwab, and H. Thoenen Cellular localization of nerve growth factor synthesis by in situ hybridization EMBO J. 1987 891 899
    • (1987) EMBO J. , pp. 891-899
    • Bandtlow, C.E.1    Heumann, R.2    Schwab, M.E.3    Thoenen, H.4
  • 4
    • 0024677597 scopus 로고
    • Trophic factors and neuronal survival
    • Y.A. Barde Trophic factors and neuronal survival Neuron 1989 1525 1534
    • (1989) Neuron , pp. 1525-1534
    • Barde, Y.A.1
  • 5
    • 0033511936 scopus 로고    scopus 로고
    • Axonal pathology in myelin disorders
    • C. Bjartmar, X. Yin, and B.D. Trapp Axonal pathology in myelin disorders J. Neurocytol. 28 1999 383 395
    • (1999) J. Neurocytol. , vol.28 , pp. 383-395
    • Bjartmar, C.1    Yin, X.2    Trapp, B.D.3
  • 7
    • 0345211489 scopus 로고    scopus 로고
    • Loss of distal axons and sensory Merkel cells and features indicative of muscle denervation in hindlimbs of P0-deficient mice
    • R. Frei, S. Mötzing, I. Kinkelin, M. Schachner, M. Koltzenburg, and R. Martini Loss of distal axons and sensory Merkel cells and features indicative of muscle denervation in hindlimbs of P0-deficient mice J. Neurosci. 19 1999 6058 6067
    • (1999) J. Neurosci. , vol.19 , pp. 6058-6067
    • Frei, R.1    Mötzing, S.2    Kinkelin, I.3    Schachner, M.4    Koltzenburg, M.5    Martini, R.6
  • 8
    • 0026615047 scopus 로고
    • Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons
    • K.P. Giese, R. Martini, G. Lemke, P. Soriano, and M. Schachner Mouse P0 gene disruption leads to hypomyelination, abnormal expression of recognition molecules, and degeneration of myelin and axons Cell 71 1992 565 576
    • (1992) Cell , vol.71 , pp. 565-576
    • Giese, K.P.1    Martini, R.2    Lemke, G.3    Soriano, P.4    Schachner, M.5
  • 9
    • 0036796227 scopus 로고    scopus 로고
    • Secondary axon atrophy and neurological dysfunction in demyelinating neuropathies
    • C.O. Hanemann, and A.A. Gabreels-Festen Secondary axon atrophy and neurological dysfunction in demyelinating neuropathies Curr. Opin. Neurol. 15 2002 611 615
    • (2002) Curr. Opin. Neurol. , vol.15 , pp. 611-615
    • Hanemann, C.O.1    Gabreels-Festen, A.A.2
  • 10
    • 0034710362 scopus 로고    scopus 로고
    • The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system
    • H.P. Hartung, and B.C. Kieseier The role of matrix metalloproteinases in autoimmune damage to the central and peripheral nervous system J. Neuroimmunol. 107 2000 140 147
    • (2000) J. Neuroimmunol. , vol.107 , pp. 140-147
    • Hartung, H.P.1    Kieseier, B.C.2
  • 11
    • 0002269358 scopus 로고
    • Immune reactions in the peripheral nervous system
    • P.J. Dyck P.K. Thomas Saunders Comp. Philadelphia
    • H.P. Hartung, G. Stoll, and K.V. Toyka Immune reactions in the peripheral nervous system P.J. Dyck P.K. Thomas Peripher. Neuropathy vol. 1 1993 Saunders Comp. Philadelphia 418 444
    • (1993) Peripher. Neuropathy , vol.1 , pp. 418-444
    • Hartung, H.P.1    Stoll, G.2    Toyka, K.V.3
  • 12
    • 0002470192 scopus 로고    scopus 로고
    • Local immune responses in the peripheral nervous system
    • J. Antel J. Birnbaum H.P. Hartung Blackwell Science Malden, USA
    • H.P. Hartung, R. Gold, and S. Jung Local immune responses in the peripheral nervous system J. Antel J. Birnbaum H.P. Hartung Clinical Neuroimmunology 1998 Blackwell Science Malden, USA 40 54 Vol.
    • (1998) Clinical Neuroimmunology , pp. 40-54
    • Hartung, H.P.1    Gold, R.2    Jung, S.3
  • 14
    • 0023256354 scopus 로고
    • Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection
    • R. Heumann, S. Korsching, C. Bandtlow, and H. Thoenen Changes of nerve growth factor synthesis in nonneuronal cells in response to sciatic nerve transection J. Cell Biol. 104 1987 1623 1631
    • (1987) J. Cell Biol. , vol.104 , pp. 1623-1631
    • Heumann, R.1    Korsching, S.2    Bandtlow, C.3    Thoenen, H.4
  • 15
    • 0023461564 scopus 로고
    • Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: Role of macrophages
    • R. Heumann, D. Lindholm, C. Bandtlow, M. Meyer, M.J. Radeke, T.P. Misko, E. Shooter, and H. Thoenen Differential regulation of mRNA encoding nerve growth factor and its receptor in rat sciatic nerve during development, degeneration, and regeneration: role of macrophages Proc. Natl. Acad. Sci. U. S. A. 84 1987 8735 8739
    • (1987) Proc. Natl. Acad. Sci. U. S. A. , vol.84 , pp. 8735-8739
    • Heumann, R.1    Lindholm, D.2    Bandtlow, C.3    Meyer, M.4    Radeke, M.J.5    Misko, T.P.6    Shooter, E.7    Thoenen, H.8
  • 16
    • 0034710340 scopus 로고    scopus 로고
    • The neuroprotective effect of inflammation: Implications for the therapy of multiple sclerosis
    • R. Hohlfeld, M. Kerschensteiner, C. Stadelmann, H. Lassmann, and H. Wekerle The neuroprotective effect of inflammation: implications for the therapy of multiple sclerosis J. Neuroimmunol. 107 2000 161 166
    • (2000) J. Neuroimmunol. , vol.107 , pp. 161-166
    • Hohlfeld, R.1    Kerschensteiner, M.2    Stadelmann, C.3    Lassmann, H.4    Wekerle, H.5
  • 17
    • 0037067053 scopus 로고    scopus 로고
    • Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat
    • P. Hu, and E.M. McLachlan Macrophage and lymphocyte invasion of dorsal root ganglia after peripheral nerve lesions in the rat Neuroscience 112 2002 23 38
    • (2002) Neuroscience , vol.112 , pp. 23-38
    • Hu, P.1    McLachlan, E.M.2
  • 18
    • 0842299503 scopus 로고    scopus 로고
    • Distinct functional types of macrophage in dorsal root ganglia and spinal nerves proximal to sciatic and spinal nerve transections in the rat
    • P. Hu, and E.M. McLachlan Distinct functional types of macrophage in dorsal root ganglia and spinal nerves proximal to sciatic and spinal nerve transections in the rat Exp. Neurol. 184 2003 590 605
    • (2003) Exp. Neurol. , vol.184 , pp. 590-605
    • Hu, P.1    McLachlan, E.M.2
  • 20
    • 0037369638 scopus 로고    scopus 로고
    • Neurotrophic cross-talk between the nervous and immune systems: Implications for neurological diseases
    • M. Kerschensteiner, C. Stadelmann, G. Dechant, H. Wekerle, and R. Hohlfeld Neurotrophic cross-talk between the nervous and immune systems: implications for neurological diseases Ann. Neurol. 53 2003 292 304
    • (2003) Ann. Neurol. , vol.53 , pp. 292-304
    • Kerschensteiner, M.1    Stadelmann, C.2    Dechant, G.3    Wekerle, H.4    Hohlfeld, R.5
  • 21
    • 0031778769 scopus 로고    scopus 로고
    • Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barre syndrome
    • B.C. Kieseier, J.M. Clements, H.B. Pischel, G.M. Wells, K. Miller, A.J. Gearing, and H.P. Hartung Matrix metalloproteinases MMP-9 and MMP-7 are expressed in experimental autoimmune neuritis and the Guillain-Barre syndrome Ann. Neurol. 43 1998 427 434
    • (1998) Ann. Neurol. , vol.43 , pp. 427-434
    • Kieseier, B.C.1    Clements, J.M.2    Pischel, H.B.3    Wells, G.M.4    Miller, K.5    Gearing, A.J.6    Hartung, H.P.7
  • 22
    • 0036499098 scopus 로고    scopus 로고
    • Macrophage-related demyelination in peripheral nerves of mice deficient in the gap junction protein connexin 32
    • I. Kobsar, M. Mäurer, T. Ott, and R. Martini Macrophage-related demyelination in peripheral nerves of mice deficient in the gap junction protein connexin 32 Neurosci. Lett. 320 2002 17 20
    • (2002) Neurosci. Lett. , vol.320 , pp. 17-20
    • Kobsar, I.1    Mäurer, M.2    Ott, T.3    Martini, R.4
  • 23
    • 0037378129 scopus 로고    scopus 로고
    • Preserved myelin integrity and reduced axonopathy in connexin32-deficient mice lacking the recombination activating gene-1
    • I. Kobsar, M. Berghoff, M. Samsam, C. Wessig, M. Maurer, K.V. Toyka, and R. Martini Preserved myelin integrity and reduced axonopathy in connexin32-deficient mice lacking the recombination activating gene-1 Brain 126 2003 804 813
    • (2003) Brain , vol.126 , pp. 804-813
    • Kobsar, I.1    Berghoff, M.2    Samsam, M.3    Wessig, C.4    Maurer, M.5    Toyka, K.V.6    Martini, R.7
  • 24
    • 0023761862 scopus 로고
    • Interleukin I increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts
    • D. Lindholm, R. Heumann, B. Hengerer, and H. Thoenen Interleukin I increases stability and transcription of mRNA encoding nerve growth factor in cultured rat fibroblasts J. Biol. Chem. 263 1988 16348 16351
    • (1988) J. Biol. Chem. , vol.263 , pp. 16348-16351
    • Lindholm, D.1    Heumann, R.2    Hengerer, B.3    Thoenen, H.4
  • 25
    • 0030696172 scopus 로고    scopus 로고
    • Animal models for inherited peripheral neuropathies
    • R. Martini Animal models for inherited peripheral neuropathies J. Anat. 191 1997 321 336
    • (1997) J. Anat. , vol.191 , pp. 321-336
    • Martini, R.1
  • 26
    • 0035078628 scopus 로고    scopus 로고
    • The effect of myelinating Schwann cells on axons
    • R. Martini The effect of myelinating Schwann cells on axons Muscle Nerve 24 2001 456 466
    • (2001) Muscle Nerve , vol.24 , pp. 456-466
    • Martini, R.1
  • 27
    • 3142540684 scopus 로고    scopus 로고
    • Immune-mediated components of hereditary demyelinating neuropathies: Lessons from animal models and patients
    • R. Martini, and K.V. Toyka Immune-mediated components of hereditary demyelinating neuropathies: lessons from animal models and patients Lancet Neurol. 3 2004 457 465
    • (2004) Lancet Neurol. , vol.3 , pp. 457-465
    • Martini, R.1    Toyka, K.V.2
  • 28
    • 0029065654 scopus 로고
    • Mice doubly deficient in the genes for P0 and myelin basic protein show that both proteins contribute to the formation of the major dense line in peripheral nerve myelin
    • R. Martini, M.H. Mohajeri, S. Kasper, K.P. Giese, and M. Schachner Mice doubly deficient in the genes for P0 and myelin basic protein show that both proteins contribute to the formation of the major dense line in peripheral nerve myelin J. Neurosci. 15 1995 4488 4495
    • (1995) J. Neurosci. , vol.15 , pp. 4488-4495
    • Martini, R.1    Mohajeri, M.H.2    Kasper, S.3    Giese, K.P.4    Schachner, M.5
  • 29
    • 0028824925 scopus 로고
    • Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies
    • R. Martini, J. Zielasek, K.V. Toyka, K.P. Giese, and M. Schachner Protein zero (P0)-deficient mice show myelin degeneration in peripheral nerves characteristic of inherited human neuropathies Nat. Genet. 11 1995 281 286
    • (1995) Nat. Genet. , vol.11 , pp. 281-286
    • Martini, R.1    Zielasek, J.2    Toyka, K.V.3    Giese, K.P.4    Schachner, M.5
  • 30
    • 0034948117 scopus 로고    scopus 로고
    • Bone marrow transfer from wild type mice reverts the beneficial effect of genetically-mediated immune deficiency in myelin mutants
    • M. Mäurer, C.D. Schmid, F. Bootz, J. Zielasek, K.V. Toyka, S. Oehen, and R. Martini Bone marrow transfer from wild type mice reverts the beneficial effect of genetically-mediated immune deficiency in myelin mutants Mol. Cell. Neurosci. 17 2001 1094 1101
    • (2001) Mol. Cell. Neurosci. , vol.17 , pp. 1094-1101
    • Mäurer, M.1    Schmid, C.D.2    Bootz, F.3    Zielasek, J.4    Toyka, K.V.5    Oehen, S.6    Martini, R.7
  • 31
    • 0036252837 scopus 로고    scopus 로고
    • Role of immune cells in animal models for inherited neuropathies: Facts and visions
    • M. Mäurer, I. Kobsar, M. Berghoff, C.D. Schmid, S. Carenini, and R. Martini Role of immune cells in animal models for inherited neuropathies: facts and visions J. Anat. 200 2002 405 414
    • (2002) J. Anat. , vol.200 , pp. 405-414
    • Mäurer, M.1    Kobsar, I.2    Berghoff, M.3    Schmid, C.D.4    Carenini, S.5    Martini, R.6
  • 32
    • 0037678523 scopus 로고    scopus 로고
    • Origin of pathogenic macrophages and endoneurial fibroblast-like cells in an animal model of inherited neuropathy
    • M. Mäurer, M. Müller, I. Kobsar, C. Leonhard, R. Martini, and R. Kiefer Origin of pathogenic macrophages and endoneurial fibroblast-like cells in an animal model of inherited neuropathy Mol. Cell. Neurosci. 23 2003 351 359
    • (2003) Mol. Cell. Neurosci. , vol.23 , pp. 351-359
    • Mäurer, M.1    Müller, M.2    Kobsar, I.3    Leonhard, C.4    Martini, R.5    Kiefer, R.6
  • 33
  • 36
    • 0037329897 scopus 로고    scopus 로고
    • Macrophage response to peripheral nerve injury: The quantitative contribution of resident and hematogenous macrophages
    • M. Mueller, C. Leonhard, K. Wacker, E.B. Ringelstein, M. Okabe, W.F. Hickey, and R. Kiefer Macrophage response to peripheral nerve injury: the quantitative contribution of resident and hematogenous macrophages Lab. Invest. 83 2003 175 185
    • (2003) Lab. Invest. , vol.83 , pp. 175-185
    • Mueller, M.1    Leonhard, C.2    Wacker, K.3    Ringelstein, E.B.4    Okabe, M.5    Hickey, W.F.6    Kiefer, R.7
  • 38
    • 0037370398 scopus 로고    scopus 로고
    • Myelin: Not just a conduit for conduction
    • B. Popko Myelin: not just a conduit for conduction Nat. Genet. 33 2003 327 328
    • (2003) Nat. Genet. , vol.33 , pp. 327-328
    • Popko, B.1
  • 39
    • 0032146068 scopus 로고    scopus 로고
    • Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration
    • G. Raivich, L.L. Jones, C.U.A. Kloss, A. Werner, H. Neumann, and G.W. Kreutzberg Immune surveillance in the injured nervous system: T-lymphocytes invade the axotomized mouse facial motor nucleus and aggregate around sites of neuronal degeneration J. Neurosci. 18 15 1998 5804 5816
    • (1998) J. Neurosci. , vol.18 , Issue.15 , pp. 5804-5816
    • Raivich, G.1    Jones, L.L.2    Kloss, C.U.A.3    Werner, A.4    Neumann, H.5    Kreutzberg, G.W.6
  • 40
    • 0037388411 scopus 로고    scopus 로고
    • The wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy
    • M. Samsam, W. Mi, C. Wessig, J. Zielasek, K.V. Toyka, M.P. Coleman, and R. Martini The wlds mutation delays robust loss of motor and sensory axons in a genetic model for myelin-related axonopathy J. Neurosci. 23 2003 2833 2839
    • (2003) J. Neurosci. , vol.23 , pp. 2833-2839
    • Samsam, M.1    Mi, W.2    Wessig, C.3    Zielasek, J.4    Toyka, K.V.5    Coleman, M.P.6    Martini, R.7
  • 43
    • 0034750675 scopus 로고    scopus 로고
    • Protective autoimmunity as a T-cell response to central nervous system trauma: Prospects for therapeutic vaccines
    • M. Schwartz Protective autoimmunity as a T-cell response to central nervous system trauma: prospects for therapeutic vaccines Prog. Neurobiol. 65 2001 489 496
    • (2001) Prog. Neurobiol. , vol.65 , pp. 489-496
    • Schwartz, M.1
  • 44
    • 4243562216 scopus 로고    scopus 로고
    • Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice
    • C.J. Serpe, A.P. Kohm, C.B. Huppenbauer, V.M. Sanders, and K.J. Jones Exacerbation of facial motoneuron loss after facial nerve transection in severe combined immunodeficient (scid) mice J. Neurosci. 19 1999 RC7
    • (1999) J. Neurosci. , vol.19
    • Serpe, C.J.1    Kohm, A.P.2    Huppenbauer, C.B.3    Sanders, V.M.4    Jones, K.J.5
  • 45
    • 0041942742 scopus 로고    scopus 로고
    • CD4+ T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection
    • C.J. Serpe, S. Coers, V.M. Sanders, and K.J. Jones CD4+ T, but not CD8+ or B, lymphocytes mediate facial motoneuron survival after facial nerve transection Brain Behav. Immun. 17 2003 393 402
    • (2003) Brain Behav. Immun. , vol.17 , pp. 393-402
    • Serpe, C.J.1    Coers, S.2    Sanders, V.M.3    Jones, K.J.4
  • 46
    • 0345561564 scopus 로고    scopus 로고
    • Nerve injury, axonal degeneration and neural regeneration: Basic insights
    • G. Stoll, and H.W. Müller Nerve injury, axonal degeneration and neural regeneration: basic insights Brain Pathol. 9 1999 313 325
    • (1999) Brain Pathol. , vol.9 , pp. 313-325
    • Stoll, G.1    Müller, H.W.2
  • 48
    • 0034752315 scopus 로고    scopus 로고
    • Disease mechanisms and potential therapeutic strategies in Charcot-Marie-Tooth disease
    • P. Young, and U. Suter Disease mechanisms and potential therapeutic strategies in Charcot-Marie-Tooth disease Brain Res. Rev. 36 2001 213 221
    • (2001) Brain Res. Rev. , vol.36 , pp. 213-221
    • Young, P.1    Suter, U.2
  • 49
    • 0028941990 scopus 로고
    • Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis
    • J. Zielasek, S. Jung, R. Gold, F.Y. Liew, K.V. Toyka, and H.P. Hartung Administration of nitric oxide synthase inhibitors in experimental autoimmune neuritis and experimental autoimmune encephalomyelitis J. Neuroimmunol. 58 1995 81 88
    • (1995) J. Neuroimmunol. , vol.58 , pp. 81-88
    • Zielasek, J.1    Jung, S.2    Gold, R.3    Liew, F.Y.4    Toyka, K.V.5    Hartung, H.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.