메뉴 건너뛰기




Volumn 59, Issue 1, 2004, Pages 67-71

Hypoxia-activated tumor pathways of angiogenesis and pH regulation independent of anemia in head-and-neck cancer

Author keywords

Anemia; Differentiated embryo chondrocyte protein; Head and neck cancer; Hypoxia inducible factor , Carbonic anhydrase 9

Indexed keywords

BLOOD; HEMOGLOBIN; OXYGEN; PATHOLOGY; PATIENT MONITORING; PH EFFECTS; SENSITIVITY ANALYSIS; TUMORS;

EID: 10444271234     PISSN: 03603016     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2003.10.016     Document Type: Article
Times cited : (46)

References (33)
  • 1
    • 0033790531 scopus 로고    scopus 로고
    • Tumour hypoxia and anemia: Impact on the efficacy of radiation therapy
    • Kumar P. Tumour hypoxia and anemia Impact on the efficacy of radiation therapy. Semin Hematol. 37:(Suppl. 6):2000;4-8.
    • (2000) Semin Hematol , vol.37 , Issue.SUPPL. 6 , pp. 4-8
    • Kumar, P.1
  • 4
    • 0036359548 scopus 로고    scopus 로고
    • Hypoxia: A key regulatory factor in tumour growth
    • Harris A.L. Hypoxia A key regulatory factor in tumour growth. Nat Rev Cancer. 2:2002;38-47.
    • (2002) Nat Rev Cancer , vol.2 , pp. 38-47
    • Harris, A.L.1
  • 5
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia inducible factors HIF-1α and HIF-2α in normal human tissues, cancers and tumor associated macrophages
    • Talks K.L., Turley H., Gatter K.C., et al. The expression and distribution of the hypoxia inducible factors HIF-1α and HIF-2α in normal human tissues, cancers and tumor associated macrophages. Am J Pathol. 157:2000;2411-2421.
    • (2000) Am J Pathol , vol.157 , pp. 2411-2421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3
  • 6
    • 0028111173 scopus 로고
    • Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment
    • Pastorek P., Pastorekova S., Callebaut I., et al. Cloning and characterization of MN, a human tumor-associated protein with a domain homologous to carbonic anhydrase and a putative helix-loop-helix DNA binding segment. Oncogene. 9:1994;2877-2888.
    • (1994) Oncogene , vol.9 , pp. 2877-2888
    • Pastorek, P.1    Pastorekova, S.2    Callebaut, I.3
  • 7
    • 0026561063 scopus 로고
    • A novel quasi-viral agent, MaTu, is a two-component system
    • Pastorekova S., Zavadova Z., Kostal M., et al. A novel quasi-viral agent, MaTu, is a two-component system. Virology. 187:1992;620-626.
    • (1992) Virology , vol.187 , pp. 620-626
    • Pastorekova, S.1    Zavadova, Z.2    Kostal, M.3
  • 8
    • 0035887489 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha is an intrinsic marker for hypoxia in cervical cancer xenografts
    • Vukovic V., Haugland H.K., Nicklee T., et al. Hypoxia-inducible factor-1alpha is an intrinsic marker for hypoxia in cervical cancer xenografts. Cancer Res. 61:2001;7394-7398.
    • (2001) Cancer Res , vol.61 , pp. 7394-7398
    • Vukovic, V.1    Haugland, H.K.2    Nicklee, T.3
  • 9
    • 0035418586 scopus 로고    scopus 로고
    • Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia: Correlations with tumour oxygen measurements and prognosis in locally advanced carcinoma of the cervix
    • Loncaster J.A., Harris A.L., Davidson S.E., et al. Carbonic anhydrase (CA IX) expression, a potential new intrinsic marker of hypoxia Correlations with tumour oxygen measurements and prognosis in locally advanced carcinoma of the cervix. Cancer Res. 61:2001;6394-6399.
    • (2001) Cancer Res , vol.61 , pp. 6394-6399
    • Loncaster, J.A.1    Harris, A.L.2    Davidson, S.E.3
  • 10
    • 0034649507 scopus 로고    scopus 로고
    • Identification of novel hypoxia dependent and independent target genes of the von Hippel Lindau (VHL) tumor suppressor by mRNA differential expression profiling
    • Wykoff C.C., Pugh C.W., Maxwell P.H., et al. Identification of novel hypoxia dependent and independent target genes of the von Hippel Lindau (VHL) tumor suppressor by mRNA differential expression profiling. Oncogene. 19:2000;6297-6305.
    • (2000) Oncogene , vol.19 , pp. 6297-6305
    • Wykoff, C.C.1    Pugh, C.W.2    Maxwell, P.H.3
  • 11
    • 0037531790 scopus 로고    scopus 로고
    • DEC1 (STRA13) protein expression relates to hypoxia inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer
    • Giatromanolaki A., Koukourakis M.I., Turley H., et al. DEC1 (STRA13) protein expression relates to hypoxia inducible factor 1-alpha and carbonic anhydrase-9 overexpression in non-small cell lung cancer. J Pathol. 200:2003;222-228.
    • (2003) J Pathol , vol.200 , pp. 222-228
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Turley, H.3
  • 12
    • 0033692793 scopus 로고    scopus 로고
    • Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors
    • Brown N.S., Jones A., Fujiyama C., et al. Thymidine phosphorylase induces carcinoma cell oxidative stress and promotes secretion of angiogenic factors. Cancer Res. 60:2000;6298-6302.
    • (2000) Cancer Res , vol.60 , pp. 6298-6302
    • Brown, N.S.1    Jones, A.2    Fujiyama, C.3
  • 13
    • 0026077991 scopus 로고
    • Radiotherapy and anaemia - The clinical experience
    • Dische S. Radiotherapy and anaemia - The clinical experience. Radiother Oncol. 20:(Suppl.):1991;35-40.
    • (1991) Radiother Oncol , vol.20 , Issue.SUPPL. , pp. 35-40
    • Dische, S.1
  • 14
    • 0033559523 scopus 로고    scopus 로고
    • Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer
    • Giatromanolaki A., Koukourakis M.I., Georgoulias V., et al. Angiogenesis vs. response after combined chemoradiotherapy of squamous cell head and neck cancer. Int J Cancer. 80:1999;810-817.
    • (1999) Int J Cancer , vol.80 , pp. 810-817
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Georgoulias, V.3
  • 15
    • 0034950003 scopus 로고    scopus 로고
    • Tumor specific activation of the VEGF/KDR angiogenic pathway in a subset of locally advanced squamous cell head and neck carcinomas
    • Giatromanolaki A., Koukourakis M.I., Sivridis E., et al. Tumor specific activation of the VEGF/KDR angiogenic pathway in a subset of locally advanced squamous cell head and neck carcinomas. Clin Exp Metastasis. 18:2000;313-319.
    • (2000) Clin Exp Metastasis , vol.18 , pp. 313-319
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Sivridis, E.3
  • 16
    • 0033952360 scopus 로고    scopus 로고
    • Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy
    • Koukourakis M.I., Giatromanolaki A., Fountzilas G., et al. Angiogenesis, thymidine phosphorylase, and resistance of squamous cell head and neck cancer to cytotoxic and radiation therapy. Clin Cancer Res. 6:2000;381-389.
    • (2000) Clin Cancer Res , vol.6 , pp. 381-389
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Fountzilas, G.3
  • 17
    • 0036680153 scopus 로고    scopus 로고
    • Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer
    • Koukourakis M.I., Giatromanolaki A., Sivridis E., et al. Hypoxia-inducible factor (HIF1A and HIF2A), angiogenesis, and chemoradiotherapy outcome of squamous cell head-and-neck cancer. Int J Radiat Oncol Biol Phys. 53:2002;1192-1202.
    • (2002) Int J Radiat Oncol Biol Phys , vol.53 , pp. 1192-1202
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Sivridis, E.3
  • 18
    • 0035181306 scopus 로고    scopus 로고
    • Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy
    • Koukourakis M.I., Giatromanolaki A., Sivridis E., et al. Hypoxia-regulated carbonic anhydrase-9 (CA9) relates to poor vascularization and resistance of squamous cell head and neck cancer to chemoradiotherapy. Clin Cancer Res. 7:2001;3399-3403.
    • (2001) Clin Cancer Res , vol.7 , pp. 3399-3403
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Sivridis, E.3
  • 19
    • 0031724056 scopus 로고    scopus 로고
    • High tumor angiogenesis is associated with poorer survival in carcinoma of the cervix treated with radiotherapy
    • Cooper R.A., Wilks D.P., Logue J.P., et al. High tumor angiogenesis is associated with poorer survival in carcinoma of the cervix treated with radiotherapy. Clin Cancer Res. 4:1998;2795-2800.
    • (1998) Clin Cancer Res , vol.4 , pp. 2795-2800
    • Cooper, R.A.1    Wilks, D.P.2    Logue, J.P.3
  • 20
    • 0035300410 scopus 로고    scopus 로고
    • Expression of hypoxia-inducible factor-1alpha: A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer
    • Aebersold D.M., Burri P., Beer K.T., et al. Expression of hypoxia-inducible factor-1alpha A novel predictive and prognostic parameter in the radiotherapy of oropharyngeal cancer. Cancer Res. 61:2001;2911-2916.
    • (2001) Cancer Res , vol.61 , pp. 2911-2916
    • Aebersold, D.M.1    Burri, P.2    Beer, K.T.3
  • 21
    • 0035266307 scopus 로고    scopus 로고
    • Hypoxia k(HIF-1α and HIF-2α) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy
    • Koukourakis M.I., Giatromanolaki A., Skarlatos J., et al. Hypoxia k(HIF-1α and HIF-2α) expression in early esophageal cancer and response to photodynamic therapy and radiotherapy. Cancer Res. 61:2001;1830-1832.
    • (2001) Cancer Res , vol.61 , pp. 1830-1832
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Skarlatos, J.3
  • 22
    • 0036023422 scopus 로고    scopus 로고
    • Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival
    • Hui E.P., Chan A.T., Pezzella F., et al. Coexpression of hypoxia-inducible factors 1alpha and 2alpha, carbonic anhydrase IX, and vascular endothelial growth factor in nasopharyngeal carcinoma and relationship to survival. Clin Cancer Res. 8:2002;2595-2604.
    • (2002) Clin Cancer Res , vol.8 , pp. 2595-2604
    • Hui, E.P.1    Chan, A.T.2    Pezzella, F.3
  • 23
    • 0036682284 scopus 로고    scopus 로고
    • Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway
    • Rapisarda A., Uranchimeg B., Scudiero D.A., et al. Identification of small molecule inhibitors of hypoxia-inducible factor 1 transcriptional activation pathway. Cancer Res. 62:2002;4316-4324.
    • (2002) Cancer Res , vol.62 , pp. 4316-4324
    • Rapisarda, A.1    Uranchimeg, B.2    Scudiero, D.A.3
  • 24
    • 0033587146 scopus 로고    scopus 로고
    • The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
    • Maxwell P.H., Wiesener M.S., Chang G.W., et al. The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis. Nature. 399:1999;271-275.
    • (1999) Nature , vol.399 , pp. 271-275
    • Maxwell, P.H.1    Wiesener, M.S.2    Chang, G.W.3
  • 25
    • 0030869787 scopus 로고    scopus 로고
    • Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element
    • Mazure N.M., Chen E.Y., Laderoute K.R., et al. Induction of vascular endothelial growth factor by hypoxia is modulated by a phosphatidylinositol 3-kinase/Akt signaling pathway in Ha-ras-transformed cells through a hypoxia inducible factor-1 transcriptional element. Blood. 90:1999;3322-3331.
    • (1999) Blood , vol.90 , pp. 3322-3331
    • Mazure, N.M.1    Chen, E.Y.2    Laderoute, K.R.3
  • 26
    • 0036789574 scopus 로고    scopus 로고
    • Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin
    • Hudson C.C., Liu M., Chiang G.G., et al. Regulation of hypoxia-inducible factor 1alpha expression and function by the mammalian target of rapamycin. Mol Cell Biol. 22:2002;7004-7014.
    • (2002) Mol Cell Biol , vol.22 , pp. 7004-7014
    • Hudson, C.C.1    Liu, M.2    Chiang, G.G.3
  • 27
    • 0034654174 scopus 로고    scopus 로고
    • Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
    • Zhong H., Chiles K., Feldser D., et al. Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells Implications for tumor angiogenesis and therapeutics. Cancer Res. 60:2000;1541-1545.
    • (2000) Cancer Res , vol.60 , pp. 1541-1545
    • Zhong, H.1    Chiles, K.2    Feldser, D.3
  • 28
    • 0029066473 scopus 로고
    • Results of an RTOG phase III trial (RTOG 85-27) comparing radiotherapy plus etanidazole with radiotherapy alone for locally advanced head and neck carcinomas
    • Lee D.J., Cosmatos D., Marcial V.A. Results of an RTOG phase III trial (RTOG 85-27) comparing radiotherapy plus etanidazole with radiotherapy alone for locally advanced head and neck carcinomas. Int J Radiat Oncol Biol Phys. 32:1995;567-576.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , pp. 567-576
    • Lee, D.J.1    Cosmatos, D.2    Marcial, V.A.3
  • 29
    • 0026059620 scopus 로고
    • What have we learnt from hyperbaric oxygen?
    • Dische S. What have we learnt from hyperbaric oxygen? Radiother Oncol. 20:(Suppl. 1):1991;71-74.
    • (1991) Radiother Oncol , vol.20 , Issue.SUPPL. 1 , pp. 71-74
    • Dische, S.1
  • 30
    • 0035555569 scopus 로고    scopus 로고
    • Squamous cell head and neck cancer: Evidence of angiogenic regeneration during radiotherapy
    • Koukourakis M.I., Giatromanolaki A., Sivridis E., et al. Squamous cell head and neck cancer Evidence of angiogenic regeneration during radiotherapy. Anticancer Res. 21:2001;4301-4309.
    • (2001) Anticancer Res , vol.21 , pp. 4301-4309
    • Koukourakis, M.I.1    Giatromanolaki, A.2    Sivridis, E.3
  • 31
    • 0035418621 scopus 로고    scopus 로고
    • Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation
    • Akakura N., Kobayashi M., Horiuchi I., et al. Constitutive expression of hypoxia-inducible factor-1alpha renders pancreatic cancer cells resistant to apoptosis induced by hypoxia and nutrient deprivation. Cancer Res. 61:2001;6548-6554.
    • (2001) Cancer Res , vol.61 , pp. 6548-6554
    • Akakura, N.1    Kobayashi, M.2    Horiuchi, I.3
  • 32
    • 0033564974 scopus 로고    scopus 로고
    • Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation
    • Gorski D.H., Beckett M.A., Jaskowiak N.T., et al. Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res. 59:1999;3374-3378.
    • (1999) Cancer Res , vol.59 , pp. 3374-3378
    • Gorski, D.H.1    Beckett, M.A.2    Jaskowiak, N.T.3
  • 33
    • 0035479076 scopus 로고    scopus 로고
    • Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer
    • Brizel D.M., Schroeder T., Scher R.L., et al. Elevated tumor lactate concentrations predict for an increased risk of metastases in head-and-neck cancer. Int J Radiat Oncol Biol Phys. 51:2001;349-353.
    • (2001) Int J Radiat Oncol Biol Phys , vol.51 , pp. 349-353
    • Brizel, D.M.1    Schroeder, T.2    Scher, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.