Dietary methoxychlor exposure modulates splenic natural killer cell activity, antibody-forming cell response and phenotypic marker expression in F 0 and F 1 generations of Sprague Dawley rats

Toxicology

Volumn 207, Issue 2, 2005, Pages 271-281

  White Jr , K L ^a   Germolec, D R ^b   Booker, C D ^a   Hernendez, D M ^a   McCay, J A ^c   Delclos, K B ^c   Newbold, R R ^b   Weis, C ^c   Guo, T L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^c NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

Developmental exposure; Endocrine disrupter; Immunomodulation; Methoxychlor; Rat

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; ISOFLAVONE; METHOXYCHLOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY PRODUCING CELL; ARTICLE; B LYMPHOCYTE; BODY WEIGHT; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DIET; ERYTHROCYTE; FEMALE; GENE EXPRESSION; HELPER CELL; IMMUNE RESPONSE; IMMUNOTOXICITY; LACTATION; MACROPHAGE; MALE; NATURAL KILLER CELL; NONHUMAN; PERINATAL PERIOD; PHENOTYPE; PRENATAL EXPOSURE; PRIORITY JOURNAL; PUERPERIUM; RAT; RAT STRAIN; SPLEEN CELL; SPLEEN WEIGHT;

ANIMALS; ANIMALS, NEWBORN; ANTIBODY-PRODUCING CELLS; DIET; FEMALE; IMMUNOGLOBULIN M; IMMUNOLOGIC FACTORS; INSECTICIDES; LYMPHOCYTE COUNT; LYMPHOCYTES; MACROPHAGES; MALE; METHOXYCHLOR; PHENOTYPE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; SEX FACTORS; SPLEEN;

ANIMALIA; OVIS ARIES;

EID: 10444267368     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tox.2004.09.011     Document Type: Article

References (42)

1. S.Y. Amstislavsky, E.A. Kizilova, A.N. Golubitsa, A.A. Vasilkova, and V.P. Eroschenko Preimplantation exposures of murine embryos to estradiol or methoxychlor change postnatal development Reprod. Toxicol. 18 2004 103 108
2. H.R.A.M. Andersson, S.F. Andersson, H. Autrup, M. Barfoed, N.A. Beresford, P. Bjerregaard, L.B. Christiansen, B. Gissel, R. Hummel, E.B. Jorgensen, B. Korsgaard, R.L. Guevel, H. Leffers, J. McLachlan, A. Moller, J.B. Nielsen, N. Olea, A. Oles-Karasko, F. Pakdel, K.L. Pedersen, P. Perez, N.E. Skakkeboek, C. Sonnenschein, A.M. Soto, J.P. Sumpter, S.M. Thorpe, and P. Grandjean Comparison of short-term estrogenicity tests for identification of hormone-disrupting chemicals Environ. Health Perspect. 107 1999 89 108
3. ATSDR, 1994. Toxicological Profile for Methoxychlor. (TP-93/11). U.S. Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry, Atlanta, GA, 1994.
4. H.S. Bal Effect of methoxychlor on reproductive systems of the rat Proc. Soc. Exp. Biol. Med. 176 1984 187 196
5. M.R. Bleavins, F.A. de la Iglesia, J.A. McCay, K.L. White Jr., and A.E. Munson Immunotoxicologic studies with CI-959, a novel benzothiophene cell activation inhibitor Toxicology 98 1995 111 123
6. R. Brunelli, D. Frasca, G. Perrone, C. Pioli, A. Fattorossi, L. Zichella, and G. Doria Hormone replacement therapy affects various immune cell subsets and natural cytotoxicity Gynecol. Obstet. Invest. 41 1996 128 131
7. W.H. Bulger, R.M. Muccitelli, and D. Kupfer Studies on the in vivo and in vitro estrogenic activities of methoxychlor and its metabolites. Role of hepatic mono-oxygenase in methoxychlor activation Biochem. Pharmacol. 27 1978 2417 2423
8. W.H. Bulger, R.M. Muccitelli, and D. Kupfer Interactions of methoxychlor, methoxychlor base-soluble contaminant, and 2,2-bis(p-hydroxyphenyl)-1,11- trichloroethane with rat uterine estrogen receptor J. Toxicol. Environ. Health. 4 1978 881 893
9. W.H. Bulger, V.J. Feil, and D. Kupfer Role of hepatic monooxygenases in generating estrogenic metabolites from methoxychlor and from its identified contaminants Mol. Pharmacol. 27 1985 115 124
10. L.A. Burns-Naas, R.W. Mast, P.C. Klykken, J.A. McCay, K.L. White Jr., P.C. Mann, and D.J. Naas Toxicology and humoral immunity assessment of decamethylcyclopentasiloxane (D5) following a 1-month whole body inhalation exposure in Fischer 344 rats Toxicol. Sci. 43 1998 28 38
11. R.E. Chapin, M.W. Harris, B.J. Davis, S.M. Ward, R.E. Wilson, M.A. Mauney, A.C. Lockhart, R.J. Smialowicz, V.C. Moser, L.T. Burka, and B.J. Collins The effects of perinatal/juvenile methoxychlor exposure on adult rat nervous, immune, and reproductive system function Fundam. Appl. Toxicol. 40 1997 138 157
12. A.M. Cummings Methoxychlor as a model for environmental estrogens Crit. Rev. Toxicol. 27 1997 367 379
13. Delclos, K.B., Newbold, R.R., 1997. A comprehensive protocol for the evaluation of reproductive, neurological, behavioral, immunological, and carcinogenic effects of potential endocrine disrupting chemicals. Presented at Estrogens in the Environment IV, Washington, D.C., July 21, 1997.
14. D.R. Doerge, M.I. Churchwell, and K.B. Delclos On-line sample preparation using restricted-access media in the analysis of the soy isoflavones, genistein and daidzein, in rat serum using liquid chromatography electrospray mass spectrometry Rapid Commun. Mass Spectrom. 14 2000 673 678
15. L.C. Folmar, M.J. Hemmer, N.D. Denslow, K. Kroll, J. Chen, A. Cheek, H. Richman, H. Meredith, and E.G. Grau A comparison of the estrogenic potencies of estradiol, ethynylestradiol, diethylstilbestrol, nonylphenol and methoxychlor in vivo and in vitro Aquat. Toxicol. 2 2002 101 110
16. D. Ghosh, J.A. Taylor, J.A. Green, and D.B. Lubahn Methoxychlor stimulates estrogen-responsive messenger ribonucleic acids in mouse uterus through a non-estrogen receptor (non-ER)α and non-ERβ mechanism Endocrinology 140 1999 3526 3533
17. 1 generations of Sprague-Dawley rats Toxicol. Appl. Pharmacol. 181 2002 219 227
18. S.J. Harris, H.C. Cecil, and J. Bitman Effect of several dietary levels of technical methoxychlor on reproduction in rats J. Agric. Food Chem. 22 1974 969 973
19. N.K. Jerne, and A.A. Nordin Plaque formation in agar by single antibody-producing cells Science 140 1963 405
20. M. Jorgensen, B. Vendelbo, N.E. Skakkebaek, and H. Leffers Assaying estrogenicity by quantitating the expression levels of endogenous estrogen-regulated genes Environ. Health Perspect. 108 2000 403 412
21. T. Kalland Reduced natural killer activity in female mice after neonatal exposure to diethylstilbestrol J. Immunol. 124 1980 1297 1300
22. I.P. Kapoor, R.L. Metcalf, R.F. Nystrom, and G.K. Sangha Comparative metabolism of methoxychlor, methiochlor, and DDT in mouse, insects, and in a model ecosystem J. Agric. Food Chem. 18 1970 1145 1152
23. L.W. Keisler, A.B. Kier, and S.E. Walker Effects of prolonged administration of the 19-nor-testosterone derivatives norethindrone and norgestrel to female NZB/W mice: comparison with methoxyprogesterone and ethinyl estradiol Autoimmunity 9 1991 21 32
24. G.G.J.M. Kuiper, B. Carlsson, K. Grandien, E. Enmark, J. Haggblad, S. Nilsson, and J. Gustafsson Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β Endocrinology 138 1997 863 870
25. G.G.J.M. Kuiper, J.G. Lemmen, B. Carlsson, J.C. Corton, S.H. Safe, P.T. van der Saag, B. van der Burg, and J. Gustafsson Interaction of estrogenic chemicals and phytoestrogens with estrogen receptor B Endocrinology 139 1998 4252 4263
26. J. Legler, C.E. van den Brink, A. Brouwer, A.J. Murk, P.T. van der Saag, A.D. Vethaak, and B. van der Burg Development of a stably transfected estrogen receptor-mediated luciferase reporter gene assay in the human T47D breast cancer cell line Toxicol. Sci. 48 1999 55 66
27. M.I. Luster, R.E. Faith, and J.A. McLachlan Alterations of the antibody response following in utero exposure to diethylstilbestrol Bull. Environ. Contam. Toxicol. 20 1978 433 437
28. M.I. Luster, R.E. Faith, J.A. McLachlan, and G.C. Clark Effect of in utero exposure to diethylstilbestrol on the immune response in mice Toxicol. Appl. Pharmacol. 47 1979 279 285
29. M.I. Luster, A.E. Munson, P.T. Thomas, M.P. Holsapple, J.D. Fenters, K.L. White Jr., L.D. Lauer, D.R. Germolec, G.J. Rosenthal, and J.H. Dean Development of a testing battery to assess chemical-induced immunotoxicity: national toxicology program's guidelines for immunotoxicity evaluation in mice Fundam. Appl. Toxicol. 10 1988 2 19
30. M.I. Luster, D.G. Pait, C. Portier, G.J. Rosenthal, D.R. Germolec, C.E. Comment, A.E. Munson, K. White, and P. Pollock Qualitative and quantitative experimental models to aid in risk assessment for immunotoxicology Toxicol. Lett. Spec No.: 71-8 1992 64 65
31. M.I. Luster, J.H. Dean, and D.R. Germolec Consensus workshop on methods to evaluate developmental immunotoxicity Environ. Health Perspect. 111 2003 579 583
32. National Research Council Hormonally active agents in the environment 1999 National Academy Press Washington, DC
33. A.C. Nimrod, and W.H. Benson Xenobiotic interaction with and alteration of channel catfish estrogen receptor Toxicol. Appl. Pharm. 147 1997 381 390
34. N.J. Olsen, and W.J. Kovacs Gonadal steroids and immunity Endocrinol. Rev. 17 1996 369 384
35. A.M. Rosenberg, K.M. Semchuk, H.H. McDuffie, D.L. Ledingham, D.M. Cordeiro, A.J. Cessna, D.G. Irvine, A. Senthilselvan, and J.A. Dosman Prevalence of antinuclear antibodies in a rural population J. Toxicol. Environ. Health 57 1999 225 236
36. P. Scaffidi, T. Misteli, and M.E. Bianchi Release of chromatin protein HMGB1 by necrotic cells triggers inflammation Nature 418 2002 191 195
37. D. Schlenk, D.M. Stresser, J.C. McCants, A.C. Nimrod, and W.H. Benson Influence of B-naphthoflavone and methoxychlor pretreatment on the biotransformation and estrogenic activity of methoxychlor in channel catfish (ictalurus punctatus) Toxicol. Appl. Pharm. 145 1997 349 356
38. J.M. Smeets, W.I. Van Holsteijn, J.P. Giesy, W. Seinen, and M. van den Berg Estrogenic potencies of several environmental pollutants, as determined by vitellogenin induction in a carp hepatocyte assay Toxicol. Sci. 50 1999 206 213
39. B. Smith, and S. Holladay Immune alterations in geriatric mice dosed subacutely with diethylstilbestrol J. Appl. Toxicol. 17 1997 265 271
40. Y. Takeuchi, T. Kosaka, K. Hayashi, M. Takeda, T. Yoshida, H. Fujisawa, S. Teramoto, K. Maita, and T. Harada Thymic atrophy induced by methoxychlor in rat pups Toxicol. Lett. 135 2002 199 207
41. S.E. Walker, L.W. Keisler, C.W. Caldwell, A.B. Kier, and F.S. vom Saal Effects of altered prenatal hormonal environment on expression of autoimmune disease in NZB/NZW mice Environ. Health Perspect. 4 1996 815 821
42. M.R. Woolhiser, and J.A. McCay Delayed assessment of immunological function allowing for transportation of lymphoid tissues to distinct laboratory sites Toxicol. Meth. 9 1999 165 171