Role of Asn-382 and Thr-383 in Activation and Inactivation of Human Prostaglandin H Synthase Cyclooxygenase Catalysis

Journal of Biological Chemistry

Volumn 279, Issue 6, 2004, Pages 4084-4092

  Bambai, Bijan ^a,c   Rogge, Corina E ^a   Stec, Boguslaw ^b   Kulmacz, Richard J ^a  

^a UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF TEXAS AT EL PASO   (United States)

^c NATIONAL INSTITUTE OF GENETIC ENGINEERING AND BIOTECHNOLOGY   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; CATALYSIS; CHEMICAL ACTIVATION; ENZYMES; FREE RADICALS; MUTAGENESIS; PEROXIDES;

ISOFORMS; MUTATIONS;

BIOCHEMISTRY;

ASPARAGINE; CYCLOOXYGENASE 2; FREE RADICAL; GLUTATHIONE PEROXIDASE; PROSTAGLANDIN SYNTHASE; THREONINE;

AMINO ACID SUBSTITUTION; ANIMAL CELL; ARTICLE; CATALYSIS; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INACTIVATION; ENZYME REGULATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HOUSEKEEPING GENE; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

ASPARAGINE; BASE SEQUENCE; CATALYSIS; CATALYTIC DOMAIN; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; DNA, COMPLEMENTARY; ENZYME ACTIVATION; ISOENZYMES; KINETICS; MODELS, BIOLOGICAL; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RECOMBINANT PROTEINS; THREONINE;

ANIMALIA;

EID: 1042289786     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M304762200     Document Type: Article

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