On the importance of atomic fluctuations, protein flexibility, and solvent in ion permeation

Journal of General Physiology

Volumn 124, Issue 6, 2004, Pages 679-690

  Allen, Toby W ^a,b   Andersen, O S ^a   Roux, Benoit ^a  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Continuum electrostatics; Crystallographic B factors; Free energy profile; Ion solvation; Poisson Boltzmann theory

Indexed keywords

GRAMICIDIN A; ION; POTASSIUM CHANNEL; PROTEIN;

ARTICLE; DIELECTRIC CONSTANT; ENERGY TRANSFER; HYDROPHOBICITY; ION TRANSPORT; MATHEMATICAL MODEL; PROTEIN FUNCTION; PROTEIN STRUCTURE; SOLVATION; TEMPERATURE DEPENDENCE;

BACTERIAL PROTEINS; COMPUTER SIMULATION; GRAMICIDIN; ION CHANNEL GATING; ION TRANSPORT; MODELS, CHEMICAL; MODELS, MOLECULAR; PERMEABILITY; POROSITY; POTASSIUM CHANNELS; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; SOLVENTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 10344245541     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409111     Document Type: Article

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