Binding of κ-conotoxin PVIIA to Shaker K+ channels reveals different K+ and Rb+ occupancies within the ion channel pore

Journal of General Physiology

Volumn 124, Issue 1, 2004, Pages 71-81

  Boccaccio, Anna ^a,d   Conti, Franco ^b   Olivera, Baldomero M ^c   Terlau, Heinrich ^a  

^a MAX PLANCK INSTITUTE OF EXPERIMENTAL MEDICINE   (Germany)

^b CNR   (Italy)

^c UNIVERSITY OF UTAH   (United States)

^d SISSA   (Italy)

Author keywords

Conotoxins; Permeation; Pore block; Voltage gated potassium channels; Xenopus oocytes

Indexed keywords

CHARYBDOTOXIN; CONOTOXIN; ION CHANNEL; KAPPA CONOTOXIN PVIIA; POTASSIUM CHANNEL; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING SITE; CHANNEL GATING; ELECTROPHYSIOLOGY; ION PERMEABILITY; MOLECULAR INTERACTION; NONHUMAN; OOCYTE; RECEPTOR BINDING; RECEPTOR OCCUPANCY; X RAY ANALYSIS; XENOPUS;

ANIMALS; CONOTOXINS; ION CHANNEL GATING; KINETICS; MEMBRANE POTENTIALS; MODELS, CHEMICAL; OOCYTES; POTASSIUM; POTASSIUM CHANNELS; RUBIDIUM; SHAKER SUPERFAMILY OF POTASSIUM CHANNELS; XENOPUS LAEVIS;

EID: 3142767519     PISSN: 00221295     EISSN: None     Source Type: Journal    
DOI: 10.1085/jgp.200409048     Document Type: Article

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