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Volumn 35, Issue 1, 2004, Pages 29-34

Tocopheryl succinate - Versatile functions due to its unique physicochemical properties

Author keywords

Tocopheryl succinate; Anti cancer; Apoptosis; Melanoma; Tumor

Indexed keywords

ALPHA TOCOPHEROL SUCCINATE; ANTINEOPLASTIC AGENT; PROTEIN KINASE C;

EID: 10044282828     PISSN: 09120009     EISSN: None     Source Type: Journal    
DOI: 10.3164/jcbn.35.29     Document Type: Review
Times cited : (1)

References (56)
  • 1
    • 0028005769 scopus 로고
    • Isolation of a vitamin E analog from a green barley leaf extract that stimulates release of prolactin and growth hormone from rat anterior pituitary cells in vitro
    • Badamchian, M., Spangelo, B.L., Bao, Y., Hagiwara, Y., Hagiwara, H., Ueyama, H., and Goldstein, A.L.: Isolation of a vitamin E analog from a green barley leaf extract that stimulates release of prolactin and growth hormone from rat anterior pituitary cells in vitro. J. Nutr. Biochem., 5, 145-150, 1994.
    • (1994) J. Nutr. Biochem. , vol.5 , pp. 145-150
    • Badamchian, M.1    Spangelo, B.L.2    Bao, Y.3    Hagiwara, Y.4    Hagiwara, H.5    Ueyama, H.6    Goldstein, A.L.7
  • 2
    • 0027310696 scopus 로고
    • Inhibition of NF-κB activation by vitamin E derivatives
    • Suzuki, Y.J. and Packer, L.: Inhibition of NF-κB activation by vitamin E derivatives. Biochem. Biophys. Res. Commun., 193, 277-283, 1993.
    • (1993) Biochem. Biophys. Res. Commun. , vol.193 , pp. 277-283
    • Suzuki, Y.J.1    Packer, L.2
  • 3
    • 0027332735 scopus 로고
    • Inhibition of NF-κB DNA binding activity by α-tocopheryl succinate
    • Suzuki, Y.J. and Packer, L.: Inhibition of NF-κB DNA binding activity by α-tocopheryl succinate. Biochem. Mol. Biol. Int., 31, 693-700, 1993.
    • (1993) Biochem. Mol. Biol. Int. , vol.31 , pp. 693-700
    • Suzuki, Y.J.1    Packer, L.2
  • 4
    • 0031906123 scopus 로고    scopus 로고
    • Inhibition of NF-κB transcriptional activity by α-tocopheryl succinate
    • Nakamura, T., Goto, M., Matsumoto, A., and Tanaka, L: Inhibition of NF-κB transcriptional activity by α-tocopheryl succinate. BioFactors, 31, 21-30, 1998.
    • (1998) BioFactors , vol.31 , pp. 21-30
    • Nakamura, T.1    Goto, M.2    Matsumoto, A.3    Tanaka, L.4
  • 5
    • 0037434422 scopus 로고    scopus 로고
    • α-Tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-κB activation
    • Dalen, H. and Neuzil, J.: α-Tocopheryl succinate sensitises a T lymphoma cell line to TRAIL-induced apoptosis by suppressing NF-κB activation. Br. J. Cancer, 88, 153-158, 2003.
    • (2003) Br. J. Cancer , vol.88 , pp. 153-158
    • Dalen, H.1    Neuzil, J.2
  • 6
    • 0036091121 scopus 로고    scopus 로고
    • Enhancement by α-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-γ through up-regulation of protein kinase C in rat vascular smooth muscle cells
    • Kogure, K., Morita, M., Hama, S., Nakashima, S., Tokumura, A., and Fukuzawa, K.: Enhancement by α-tocopheryl hemisuccinate of nitric oxide production induced by lypopolysaccharide and interferon-γ through up-regulation of protein kinase C in rat vascular smooth muscle cells. Eur. J. Biochem., 269, 2367-2372, 2002.
    • (2002) Eur. J. Biochem. , vol.269 , pp. 2367-2372
    • Kogure, K.1    Morita, M.2    Hama, S.3    Nakashima, S.4    Tokumura, A.5    Fukuzawa, K.6
  • 7
    • 0028229468 scopus 로고
    • The selective antiproliferative effects of α-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds
    • Fariss, M.W., Fortuna, M.B., Everett, C.K., Smith, J.D., Trent, D.F., and Djuric, Z.: The selective antiproliferative effects of α-tocopheryl hemisuccinate and cholesteryl hemisuccinate on murine leukemia cells result from the action of the intact compounds. Cancer Res., 54, 3346-3351, 1994.
    • (1994) Cancer Res. , vol.54 , pp. 3346-3351
    • Fariss, M.W.1    Fortuna, M.B.2    Everett, C.K.3    Smith, J.D.4    Trent, D.F.5    Djuric, Z.6
  • 8
    • 0029005530 scopus 로고
    • Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: Role for transforming growth factor-β
    • Turley, J.M., Funakoshi, S., Ruscetti, F.W., Kasper, J., Murphy, W.J., Longo, D.L., and Birchenall-Roberts, M.C.: Growth inhibition and apoptosis of RL human B lymphoma cells by vitamin E succinate and retinoic acid: role for transforming growth factor-β. Cell Growth Differ., 6, 655-663, 1995.
    • (1995) Cell Growth Differ. , vol.6 , pp. 655-663
    • Turley, J.M.1    Funakoshi, S.2    Ruscetti, F.W.3    Kasper, J.4    Murphy, W.J.5    Longo, D.L.6    Birchenall-Roberts, M.C.7
  • 9
    • 0035801839 scopus 로고    scopus 로고
    • Superoxide is responsible for apoptosis in rat vascular smooth muscle cells induced by α-tocopheryl succinate
    • Kogure, K., Morita, M., Nakashima, S., Hama, S., Tokumura, A., and Fukuzawa, K.: Superoxide is responsible for apoptosis in rat vascular smooth muscle cells induced by α-tocopheryl succinate. Biochim. Biophys. Acta, 1528, 25-30, 2001.
    • (2001) Biochim. Biophys. Acta , vol.1528 , pp. 25-30
    • Kogure, K.1    Morita, M.2    Nakashima, S.3    Hama, S.4    Tokumura, A.5    Fukuzawa, K.6
  • 10
    • 0037027755 scopus 로고    scopus 로고
    • High cytotoxicity of α-tocopheryl hemisuccinate to cancer cells is due to failure of their antioxidative defense systems
    • Kogure, K., Hama, S., Manabe, S., Tokumura, A., and Fukuzawa, K.: High cytotoxicity of α-tocopheryl hemisuccinate to cancer cells is due to failure of their antioxidative defense systems. Cancer Lett., 186, 151-156, 2002.
    • (2002) Cancer Lett. , vol.186 , pp. 151-156
    • Kogure, K.1    Hama, S.2    Manabe, S.3    Tokumura, A.4    Fukuzawa, K.5
  • 11
    • 1942510597 scopus 로고    scopus 로고
    • Structural characteristic of terminal dicarboxylic moiety required for apoptogenic activity of α-Tocopheryl esters
    • Kogure, K., Hama, S., Kisaki, M., Takemasa, H., Tokumura, A., Suzuki, I., and Fukuzawa, K.: Structural characteristic of terminal dicarboxylic moiety required for apoptogenic activity of α-Tocopheryl esters. Biochim. Biophys. Acta, 1672, 93-99, 2004.
    • (2004) Biochim. Biophys. Acta , vol.1672 , pp. 93-99
    • Kogure, K.1    Hama, S.2    Kisaki, M.3    Takemasa, H.4    Tokumura, A.5    Suzuki, I.6    Fukuzawa, K.7
  • 12
    • 0034927296 scopus 로고    scopus 로고
    • Vitamin E analogues as inducers of apoptosis: Implications for their potential antineoplastic role
    • Neuzil, J., Weber, T., Terman, A., Weber, C., and Brunk, U.T.: Vitamin E analogues as inducers of apoptosis: implications for their potential antineoplastic role. Redox Rep., 6, 143-151, 2001.
    • (2001) Redox Rep. , vol.6 , pp. 143-151
    • Neuzil, J.1    Weber, T.2    Terman, A.3    Weber, C.4    Brunk, U.T.5
  • 13
    • 0035901479 scopus 로고    scopus 로고
    • Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage
    • Neuzil, J., Schröder, A., Hundelshausen, P., Zernecke, A., Weber, T., Gellert, N., and Weber, C.: Inhibition of inflammatory endothelial responses by a pathway involving caspase activation and p65 cleavage. Biochemistry, 40, 4686-4692, 2001.
    • (2001) Biochemistry , vol.40 , pp. 4686-4692
    • Neuzil, J.1    Schröder, A.2    Hundelshausen, P.3    Zernecke, A.4    Weber, T.5    Gellert, N.6    Weber, C.7
  • 15
    • 0035137727 scopus 로고    scopus 로고
    • Selective cancer cell killing by α-tocopheryl succinate
    • Neuzil, J., Weber, T., Gellert, N., and Weber, C.: Selective cancer cell killing by α-tocopheryl succinate. Br. J. Cancer, 84, 87-89, 2001.
    • (2001) Br. J. Cancer , vol.84 , pp. 87-89
    • Neuzil, J.1    Weber, T.2    Gellert, N.3    Weber, C.4
  • 16
    • 0030762061 scopus 로고    scopus 로고
    • c-Jun involvement in vitamin E succinate induced apoptosis of reticuloendotheliosis virus transformed avian lymphoid cells
    • Qian, M., Kralova, J., Yu, W., Bose, H.R. Jr., Dvorak, M., Sanders, B.G., and Kline, K.: c-Jun involvement in vitamin E succinate induced apoptosis of reticuloendotheliosis virus transformed avian lymphoid cells. Oncogene, 15, 223-230, 1997.
    • (1997) Oncogene , vol.15 , pp. 223-230
    • Qian, M.1    Kralova, J.2    Yu, W.3    Bose Jr., H.R.4    Dvorak, M.5    Sanders, B.G.6    Kline, K.7
  • 18
  • 19
    • 0034799471 scopus 로고    scopus 로고
    • RRR-α-Tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation
    • You, H., Yu, W., Sanders, B.G., and Kline, K.: RRR-α-Tocopheryl succinate induces MDA-MB-435 and MCF-7 human breast cancer cells to undergo differentiation. Cell Growth Differ., 12, 471-480, 2001.
    • (2001) Cell Growth Differ. , vol.12 , pp. 471-480
    • You, H.1    Yu, W.2    Sanders, B.G.3    Kline, K.4
  • 20
    • 0030934111 scopus 로고    scopus 로고
    • Evidence for role of transforming growth factor-β in RRR-α-tocopheryl succinate-induced apoptosis of human MDA-MB-435 breast cancer cells
    • Yu, W., Heim, K., Qian, M., Simmons-Menchaca, M., Sanders, B.G., and Kline, K.: Evidence for role of transforming growth factor-β in RRR-α-tocopheryl succinate-induced apoptosis of human MDA-MB-435 breast cancer cells. Nutr. Cancer, 27, 267-278, 1997.
    • (1997) Nutr. Cancer , vol.27 , pp. 267-278
    • Yu, W.1    Heim, K.2    Qian, M.3    Simmons-Menchaca, M.4    Sanders, B.G.5    Kline, K.6
  • 21
    • 0033557969 scopus 로고    scopus 로고
    • Vitamin E succinate (VES) induced Fas sensitivity in human breast cancer cells: Role for Mr 43,000 Fas in VES-triggered apoptosis
    • Yu, W., Israel, K., Liao, Q.Y., Aldaz, C.M., Sanders, B.G., and Kline, K.: Vitamin E succinate (VES) induced Fas sensitivity in human breast cancer cells: role for Mr 43,000 Fas in VES-triggered apoptosis. Cancer Res., 59, 953-961, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 953-961
    • Yu, W.1    Israel, K.2    Liao, Q.Y.3    Aldaz, C.M.4    Sanders, B.G.5    Kline, K.6
  • 22
    • 0035418623 scopus 로고    scopus 로고
    • 2-terminal kinase but not p38 mitogen-activated protein kinase is required for RRR-α-tocopheryl succinate-induced apoptosis of human breast cancer cells
    • 2-terminal kinase but not p38 mitogen-activated protein kinase is required for RRR-α-tocopheryl succinate-induced apoptosis of human breast cancer cells. Cancer Res., 61, 6569-6576, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 6569-6576
    • Yu, W.1    Liao, Q.Y.2    Hantash, F.M.3    Sanders, B.G.4    Kline, K.5
  • 23
    • 0021988229 scopus 로고
    • Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipids membranes
    • Lai, M.-Z., Düzgünes, N., and Szoka, F.C.: Effects of replacement of the hydroxyl group of cholesterol and tocopherol on the thermotropic behavior of phospholipids membranes. Biochemistry, 24, 1646-1653, 1985.
    • (1985) Biochemistry , vol.24 , pp. 1646-1653
    • Lai, M.-Z.1    Düzgünes, N.2    Szoka, F.C.3
  • 25
    • 0035076782 scopus 로고    scopus 로고
    • Interfacial properties of phosphatidylcholine bilayers containing vitamin E derivatives
    • Massey, J.B.: Interfacial properties of phosphatidylcholine bilayers containing vitamin E derivatives. Chem. Phys. Lipids, 109, 157-174, 2001.
    • (2001) Chem. Phys. Lipids , vol.109 , pp. 157-174
    • Massey, J.B.1
  • 26
    • 0018336717 scopus 로고
    • Effect of α-tocopherol incorporation on glucose permeability and phase transition of lecithin liposomes
    • Fukuzawa, K., Ikeno, H., Tokumura, A., and Tsukatani, H.: Effect of α-tocopherol incorporation on glucose permeability and phase transition of lecithin liposomes. Chem. Phys. Lipids, 23, 13-22, 1979.
    • (1979) Chem. Phys. Lipids , vol.23 , pp. 13-22
    • Fukuzawa, K.1    Ikeno, H.2    Tokumura, A.3    Tsukatani, H.4
  • 27
    • 0019215490 scopus 로고
    • Fluorescence depolarization studies of phase trasition and fluidity in lecithin liposomes containing α-tocopherol
    • Fukuzawa, K., Chida, H., and Suzuki, A.: Fluorescence depolarization studies of phase trasition and fluidity in lecithin liposomes containing α-tocopherol. J. Nutr. Sci. Vitaminol., 26, 427-434, 1980.
    • (1980) J. Nutr. Sci. Vitaminol. , vol.26 , pp. 427-434
    • Fukuzawa, K.1    Chida, H.2    Suzuki, A.3
  • 28
    • 0028027091 scopus 로고
    • pH-Sensitive liposomes composed of tocopherol hemisuccinate and of phosphatidylethanolamine including tocopherol hemisuccinate
    • Jizomoto, H., Kanaoka, E., and Hirano, K.: pH-Sensitive liposomes composed of tocopherol hemisuccinate and of phosphatidylethanolamine including tocopherol hemisuccinate. Biochim. Biophys. Acta, 1213, 343-348, 1984.
    • (1984) Biochim. Biophys. Acta , vol.1213 , pp. 343-348
    • Jizomoto, H.1    Kanaoka, E.2    Hirano, K.3
  • 29
    • 0036389582 scopus 로고    scopus 로고
    • Vitamin E succinate inhibits colon cancer liver metastases
    • Barnett, K.T., Fokum, F.D., and Malafa, M.P.: Vitamin E succinate inhibits colon cancer liver metastases. J. Surg. Res., 106, 292-298, 2002.
    • (2002) J. Surg. Res. , vol.106 , pp. 292-298
    • Barnett, K.T.1    Fokum, F.D.2    Malafa, M.P.3
  • 30
    • 0033856407 scopus 로고    scopus 로고
    • Vitamin E succinate promotes breast cancer tumor dormancy
    • Malafa, M.P. and Neitzel, L.T.: Vitamin E succinate promotes breast cancer tumor dormancy. J. Surg. Res., 93, 163-170, 2000.
    • (2000) J. Surg. Res. , vol.93 , pp. 163-170
    • Malafa, M.P.1    Neitzel, L.T.2
  • 32
    • 0036896183 scopus 로고    scopus 로고
    • Inhibition of angiogenesis and promotion of melanoma dormancy by vitamin E succinate
    • Malafa, M.P., Fokum, F.D., Smith, L., and Louis, A.: Inhibition of angiogenesis and promotion of melanoma dormancy by vitamin E succinate. Ann. Surg. Ongol., 9, 1023-1032, 2002.
    • (2002) Ann. Surg. Ongol. , vol.9 , pp. 1023-1032
    • Malafa, M.P.1    Fokum, F.D.2    Smith, L.3    Louis, A.4
  • 34
    • 0030681273 scopus 로고    scopus 로고
    • Liposomes: Opportunities in drug delivery
    • Allen, T.M.: Liposomes: Opportunities in drug delivery. Drugs, 54, 8-14, 1997.
    • (1997) Drugs , vol.54 , pp. 8-14
    • Allen, T.M.1
  • 35
    • 0037456691 scopus 로고    scopus 로고
    • Potentiation of anti-cancer effect by intra venous administration of vesiculated α-tocopheryl hemisuccinate on mouse melanoma in vivo
    • Kogure, K., Manabe, S., Hama, S., Tokumura, A., and Fukuzawa, K.: Potentiation of anti-cancer effect by intra venous administration of vesiculated α-tocopheryl hemisuccinate on mouse melanoma in vivo. Cancer Lett., 192, 19-24, 2003.
    • (2003) Cancer Lett. , vol.192 , pp. 19-24
    • Kogure, K.1    Manabe, S.2    Hama, S.3    Tokumura, A.4    Fukuzawa, K.5
  • 36
    • 0037898519 scopus 로고    scopus 로고
    • Vitamin E analogues as inducers of apoptosis: Structure-function relation
    • Birringer, M., EyTina, J.H., Salvatore, B.A., and Neuzil, J.: Vitamin E analogues as inducers of apoptosis: structure-function relation. Br. J. Cancer, 88, 1948-1955, 2003.
    • (2003) Br. J. Cancer , vol.88 , pp. 1948-1955
    • Birringer, M.1    EyTina, J.H.2    Salvatore, B.A.3    Neuzil, J.4
  • 37
    • 0031022378 scopus 로고    scopus 로고
    • RRR-α-Tocopheryl succinate inhibits EL4 thymic lymphoma cell growth by inducing apoptosis and DNA synthesis arrest
    • Yu, W., Sanders, B.G., and Kline, K.: RRR-α-Tocopheryl succinate inhibits EL4 thymic lymphoma cell growth by inducing apoptosis and DNA synthesis arrest. Nutr. Cancer, 27, 92-101, 1997.
    • (1997) Nutr. Cancer , vol.27 , pp. 92-101
    • Yu, W.1    Sanders, B.G.2    Kline, K.3
  • 38
    • 0036791608 scopus 로고    scopus 로고
    • The effects of vitamin E succinate on the expression of c-Jun gene and protein in human gastric cancer SGC-7901 cells
    • Zhao, Y., Wu, K., Xia, W., Shan, Y.-J., Wu, L.-J., and Yu, W.-P.: The effects of vitamin E succinate on the expression of c-Jun gene and protein in human gastric cancer SGC-7901 cells. World J. Gastroenterol., 8, 782-786, 2002.
    • (2002) World J. Gastroenterol. , vol.8 , pp. 782-786
    • Zhao, Y.1    Wu, K.2    Xia, W.3    Shan, Y.-J.4    Wu, L.-J.5    Yu, W.-P.6
  • 39
    • 0034074981 scopus 로고    scopus 로고
    • Vitamin E succinate induces apoptosis in human prostate cancer cells: Role for Fas in vitamin E succinate-triggered apoptosis
    • Israel, K., Yu, W., Sanders, B.G., and Kline, K.: Vitamin E succinate induces apoptosis in human prostate cancer cells: role for Fas in vitamin E succinate-triggered apoptosis. Nutr. Cancer, 36, 90-100, 2000.
    • (2000) Nutr. Cancer , vol.36 , pp. 90-100
    • Israel, K.1    Yu, W.2    Sanders, B.G.3    Kline, K.4
  • 40
    • 0036900950 scopus 로고    scopus 로고
    • Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells
    • Wu, K., Li, Y., Zhao, Y., Shan, Y.-J., Xia, W., Yu, W.-P., and Zhao, L.: Roles of Fas signaling pathway in vitamin E succinate-induced apoptosis in human gastric cancer SGC-7901 cells. World J. Gastroenterol., 8, 982-986, 2002.
    • (2002) World J. Gastroenterol. , vol.8 , pp. 982-986
    • Wu, K.1    Li, Y.2    Zhao, Y.3    Shan, Y.-J.4    Xia, W.5    Yu, W.-P.6    Zhao, L.7
  • 41
    • 0037086662 scopus 로고    scopus 로고
    • α-Tocopheryl succinate, an agent with in vito anti-tumor activity, induces apoptosis by causing lysosomal instability
    • Neuzil, J., Zhao, M., Ostermann, G., Sticha, M., Gellert, N., Weber, C., Eaton, J.W., and Brunk, U.T.: α-Tocopheryl succinate, an agent with in vito anti-tumor activity, induces apoptosis by causing lysosomal instability. Biochem. J., 362, 709-715, 2002.
    • (2002) Biochem. J. , vol.362 , pp. 709-715
    • Neuzil, J.1    Zhao, M.2    Ostermann, G.3    Sticha, M.4    Gellert, N.5    Weber, C.6    Eaton, J.W.7    Brunk, U.T.8
  • 42
    • 0035834597 scopus 로고    scopus 로고
    • Activation of PKC but not of ERK is required for vitamin E-succinate induced apoptosis of HL-60 cells
    • Bang, O.-S., Park, J.-H., and Kang, S.-S.: Activation of PKC but not of ERK is required for vitamin E-succinate induced apoptosis of HL-60 cells. Biochem. Biophys. Res. Commun., 288, 789-797, 2001.
    • (2001) Biochem. Biophys. Res. Commun. , vol.288 , pp. 789-797
    • Bang, O.-S.1    Park, J.-H.2    Kang, S.-S.3
  • 44
    • 0036216407 scopus 로고    scopus 로고
    • Role of extracellular signal-regulated kinase pathway in RRR-α-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells
    • You, H., Yu, W., Munoz-Medelline, D., Brown, P.H., Sanders, B.G., and Kline, K.: Role of extracellular signal-regulated kinase pathway in RRR-α-tocopheryl succinate-induced differentiation of human MDA-MB-435 breast cancer cells. Mol. Carcinog., 33, 228-236, 2002.
    • (2002) Mol. Carcinog. , vol.33 , pp. 228-236
    • You, H.1    Yu, W.2    Munoz-Medelline, D.3    Brown, P.H.4    Sanders, B.G.5    Kline, K.6
  • 45
    • 0037187065 scopus 로고    scopus 로고
    • WAF1 is dependent on the activation of ERK during vitamin E-succinate-induced monocytic differentiation
    • WAF1 is dependent on the activation of ERK during vitamin E-succinate-induced monocytic differentiation. Mol. Cells, 13, 125-129, 2002.
    • (2002) Mol. Cells , vol.13 , pp. 125-129
    • Lee, J.-K.1    Jung, J.C.2    Chun, J.-S.3    Kang, S.-S.4    Bang, O.-S.5
  • 46
    • 1942489375 scopus 로고    scopus 로고
    • Enhancement of nitric oxide and superoxide generation by α-tocopheryl succinate and its apoptotic and anticancer effects
    • Fukuzawa, K., Kogure, K., Morita, M., Hama, S., Manabe, S., and Tokumura, A.: Enhancement of nitric oxide and superoxide generation by α-tocopheryl succinate and its apoptotic and anticancer effects. Biochemistry (Moscow), 69, 64-73, 2004.
    • (2004) Biochemistry (Moscow) , vol.69 , pp. 64-73
    • Fukuzawa, K.1    Kogure, K.2    Morita, M.3    Hama, S.4    Manabe, S.5    Tokumura, A.6
  • 48
    • 0029789967 scopus 로고    scopus 로고
    • Protein kinase C δ activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf
    • Ueda, Y., Hirai, S., Osada, S., Suzuki, A., Mizuno, K., and Ohno, S.: Protein kinase C δ activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf. J. Biol. Chem., 271, 23512-23519, 1996.
    • (1996) J. Biol. Chem. , vol.271 , pp. 23512-23519
    • Ueda, Y.1    Hirai, S.2    Osada, S.3    Suzuki, A.4    Mizuno, K.5    Ohno, S.6
  • 49
    • 0033028510 scopus 로고    scopus 로고
    • Signal perception and transduction: The role of protein kinases
    • Schenk, P.W. and Snaar-Jagalska, B.: Signal perception and transduction: the role of protein kinases. Biochim. Biophys. Acta, 1449, 1-24, 1999.
    • (1999) Biochim. Biophys. Acta , vol.1449 , pp. 1-24
    • Schenk, P.W.1    Snaar-Jagalska, B.2
  • 50
    • 0031563140 scopus 로고    scopus 로고
    • Induction of apoptosis through the PKC pathway in cultured dermal papilla fibroblasts
    • Ferraris, C., Cooklis, M., Polakowska, R.R., and Haake, A.R.: Induction of apoptosis through the PKC pathway in cultured dermal papilla fibroblasts. Exp. Cell Res., 234, 37-46, 1997.
    • (1997) Exp. Cell Res. , vol.234 , pp. 37-46
    • Ferraris, C.1    Cooklis, M.2    Polakowska, R.R.3    Haake, A.R.4
  • 51
    • 0031282980 scopus 로고    scopus 로고
    • Activation of PKCα downstream from caspases during apoptosis induced by 7-hydroxystaurosporin or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells
    • Shao, R.-G., Cao, C.-X., and Pommier, Y.: Activation of PKCα downstream from caspases during apoptosis induced by 7-hydroxystaurosporin or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells. J. Biol. Chem., 272, 31321-31325, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 31321-31325
    • Shao, R.-G.1    Cao, C.-X.2    Pommier, Y.3
  • 53
    • 0028979464 scopus 로고
    • Crystal structure of the cys2 activator-binding domain of protein kinase C δ in complex with phorbol ester
    • Zhang, G., Kazanietz, M.G., Blumberg, P.M., and Hurley, J.H.: Crystal structure of the cys2 activator-binding domain of protein kinase C δ in complex with phorbol ester. Cell, 81, 917-924, 1995.
    • (1995) Cell , vol.81 , pp. 917-924
    • Zhang, G.1    Kazanietz, M.G.2    Blumberg, P.M.3    Hurley, J.H.4
  • 54
    • 0023851550 scopus 로고    scopus 로고
    • Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease
    • Kramer, I.M., Verhoeven, A.J., van der Bend, R.L., Weening, R.S., and Roos, D.: Purified protein kinase C phosphorylates a 47-kDa protein in control neutrophil cytoplasts but not in neutrophil cytoplasts from patients with the autosomal form of chronic granulomatous disease. J. Biol. Chem., 263, 2352-2357, 1998.
    • (1998) J. Biol. Chem. , vol.263 , pp. 2352-2357
    • Kramer, I.M.1    Verhoeven, A.J.2    Van Der Bend, R.L.3    Weening, R.S.4    Roos, D.5
  • 56
    • 0002589191 scopus 로고
    • Vitamin E succinate inhibits protein kinase C: Correlation with its unique inhibitory effects on cell growth and transformation
    • ed. by Prasad, K.N., Human Press, Totawa, NJ
    • Gopalakrishna, R., Gundimeda, U., and Chen, Z.: Vitamin E succinate inhibits protein kinase C: Correlation with its unique inhibitory effects on cell growth and transformation, in Nutrients and Cancer, ed. by Prasad, K.N., Human Press, Totawa, NJ, pp. 21-37, 1995.
    • (1995) Nutrients and Cancer , pp. 21-37
    • Gopalakrishna, R.1    Gundimeda, U.2    Chen, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.