Activation of PKCα downstream from caspases during apoptosis induced by 7-hydroxystaurosporine or the topoisomerase inhibitors, camptothecin and etoposide, in human myeloid leukemia HL60 cells

Journal of Biological Chemistry

Volumn 272, Issue 50, 1997, Pages 31321-31325

  Shao, Rong Guang ^a   Cao, Chun Xia ^a   Pommier, Yves ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

7 HYDROXYSTAUROSPORINE; CAMPTOTHECIN; DNA TOPOISOMERASE INHIBITOR; ETOPOSIDE; PROTEIN KINASE C; 7-HYDROXYSTAUROSPORINE; ALKALOID; ANTINEOPLASTIC AGENT; BENZYLOXYCARBONYLVALYL ALANYL ASPARTYL FLUOROMETHYL KETONE; BENZYLOXYCARBONYLVALYL-ALANYL-ASPARTYL FLUOROMETHYL KETONE; CYSTEINE PROTEINASE; CYSTEINE PROTEINASE INHIBITOR; DRUG DERIVATIVE; ENZYME INHIBITOR; ISOENZYME; PEPTIDE CHLOROMETHYL KETONE; PRKCA PROTEIN, HUMAN; PROTEIN KINASE C ALPHA; STAUROSPORINE;

APOPTOSIS; ARTICLE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MYELOID LEUKEMIA; PRIORITY JOURNAL; PROTEIN DEGRADATION; CELL STRAIN HL 60; DRUG ANTAGONISM; DRUG EFFECT; METABOLISM; UPREGULATION;

ALKALOIDS; AMINO ACID CHLOROMETHYL KETONES; ANTINEOPLASTIC AGENTS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CAMPTOTHECIN; CYSTEINE ENDOPEPTIDASES; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; ENZYME INHIBITORS; ETOPOSIDE; HL-60 CELLS; HUMANS; ISOENZYMES; PROTEIN KINASE C; PROTEIN KINASE C-ALPHA; STAUROSPORINE; UP-REGULATION;

EID: 0031282980     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.272.50.31321     Document Type: Article

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