Analysis of the role of intraprotein electron transfer in photoreactivation by DNA photolyase in vivo

Biochemistry

Volumn 43, Issue 48, 2004, Pages 15103-15110

  Kavakli, I Halil ^a   Sancar, Aziz ^a,b  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYST ACTIVITY; CHROMOSOMES; DNA; ESCHERICHIA COLI; GENES; OXIDATION; PHOTOREACTIVITY; PROTEINS;

DNA PHOTOLAYSE; PHOTOREPAIR;

ELECTRON TRANSITIONS;

DEOXYRIBODIPYRIMIDINE PHOTOLYASE; FLAVINE ADENINE NUCLEOTIDE;

ARTICLE; CATALYSIS; CHROMOSOME MUTATION; CONTROLLED STUDY; DNA REPAIR; ELECTRON TRANSPORT; ESCHERICHIA COLI; IN VIVO STUDY; NONHUMAN; PHOTOREACTIVATION; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FUNCTION; WILD TYPE;

CATALYSIS; DEOXYRIBODIPYRIMIDINE PHOTO-LYASE; DNA REPAIR; ELECTRON TRANSPORT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FLAVIN-ADENINE DINUCLEOTIDE; PHENYLALANINE; PHOTOCHEMISTRY; PYRIMIDINE DIMERS; TRYPTOPHAN;

ESCHERICHIA COLI;

EID: 10044280356     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi0478796     Document Type: Article

References (33)

1. Carell, T., Burgdorf, L. T., Kundu, L. M., and Cichon, M. (2001) The mechanism of action of DNA photolyases, Curr. Opin. Chem. Biol. 5, 491-498.
2. Sancar, C. (2003) Structure and function of DNA photolyase and cryptochrome blue-light photoreceptors, Chem. Rev. 103, 2203-2238.
3. Jorns, M. S., Sancar, G. B., and Sancar, A. (1984) Identification of a neutral flavin radical and characterization of a second chromophore in E. coli DNA photolyase. Biochemistry 23, 2673-2679.
4. Jorns, M. S., Baldwin, E. T., Sancar, G. B., and Sancar, A. (1987) Action mechanism of E. coli DNA photolyase. II. Role of the chromophores in catalysis, J. Biol. Chem. 262, 486-491.
5. Sancar, G. B., Jorns, M. S., Payne, G., Fluke, D. J., Rupert, C. S., and Sancar, A. (1987) Action mechanism of E. coli DNA photolyase. III. Photolysis of the ES complex and the absolute action spectrum, J. Biol. Chem. 262, 492-498.
6. Heelis, P. F., Payne, G. P., and Sancar, A. (1987) Photochemical properties of Escherichia coli DNA photolyase: Selective decomposition of the second chromophore, Biochemistry 26, 4634-4640.
7. Li, Y. F., Heelis, P. F., and Sancar, A. (1991) Active site of DNA photolyase: Trp306 is the intrinsic H-atom donor essential for flavin radical photoreduction and DNA repair in vitro, Biochemistry 30, 6322-6329.
8. -, the catalytically active form of the cofactor, Proc. Natl. Acad. Sci. U.S.A. 90, 8023-8027.
9. Zhong, D., and Zewail, A. (2001) Femtosecond dynamics of flavoproteins: Charge separation and recombination in riboflavin (vitamin B2)-binding protein and glucose oxidase enzyme, Proc. Natl. Acad. Sci. U.S.A. 98, 11867-11872.
10. Park, H. W., Kim, S. T., Sancar, A., and Deisenhofer, J. (1995) Crystal structure of DNA photolyase from Escherichia coli, Science 268, 1866-1872.
11. Sancar, A. (1994) Structure and function of DNA photolyase, Biochemistry 33, 2-9.
12. •, Biophys. J. 76, 1241-1249.
13. Gindt, Y. M., Vollenbroek, E., Westphal, K., Sackett, H., Sancar, A., and Babcock, G. T. (1999) The origin of the transient EPR signal in DNA photolyase, Biochemistry 38, 3857-3866.
14. Aubert, C., Vos, M. H., Mathis, P., Ecker, A. P. M., and Brettel, K. (2000) Intraprotein radical transfer during photoactivation of DNA photolyase, Nature 405, 586-590.
15. Byrdin, M., Eker, A. P. M., Vos, M. H., and Brettel, K. (2003 Dissection of the triple tryptophan electron-transfer chain in Escherichia coli DNA photolyase: Trp382 is the primary donor in photoactivation, Proc. Natl. Acad. Sci. U.S.A. 100, 8676-8681.
16. Kapetanaki, S. M., Ramsey, M., Gindt, Y. M., and Schelvis, J. P. M. (2004) Substrate electric dipole moment exerts a pH-dependent effect on electron transfer in Escherichia coli photolyase, J. Am. Chem. Soc. 126, 6214-6215.
17. Weber, S., Möbius, K., Richter, G., and Kay, C. W. M. (2001) The electronic structure of the flavin cofactor in DNA photolyase, J. Am. Chem. Soc. 123, 3790-3798.
18. MacFarlane, A. W., and Stanley, R. J. (2003) Cis-syn thymidine dimer repair by DNA photolyase in real time, Biochemistry 42, 8558-8568.
19. Giovani, B., Byrdin, M., Ahmad, M., and Brettel, K. (2003) Light induced electron transfer in a cryptochrome blue-light photoreceptor. Nat. Struct. Biol. 10, 489-490.
20. Brautigam, C. A., Smith, B. S., Ma, Z., Palmitkar, M., Tomchick, D. R., Machius, M., and Deisenhofer, J. (2004) Structure of the photolyase-like domain of cryptochrome 1 from Arabidopsis thaliana, Proc. Natl. Acad. Sci. U.S.A. 101, 12142-12147.
21. Husain, I., and Sancar, A. (1987) Photoreactivation in the phr mutants of Escherichia coli K-12, J. Bacteriol. 169, 2367-2372.
22. - cells is not caused by pyrimidine dimer reversal. Photochem. Photobiol. 48, 233-234.
23. Haldimann, A., and Wanner, B. L. (2001) Conditional-replication, integration, excision, and retrieval plasmid-host systems for gene structure-function studies of bacteria, J. Bacteriol. 183, 6384-6393.
24. Worthington, E. N., Kavakli, I. H., Berrocal-Tito, G., Bondo, B. E., and Sancar, A. (2003) Purification and characterization of three members of the photolyase/cryptochrome family blue-light photoreceptors from Vibrio cholerae, J. Biol. Chem. 278, 39143-39154.
25. Setlow, R. B., and Carrier, W. L. (1966) Pyrimidine dimers in ultraviolet-irradiated DNAs, J. Mol. Biol. 17, 237-254.
26. Harm, W., Harm, H., and Rupert, C. S. (1968) Analysis of photoenzymatic repair of UV lesions in DNA by single light flashes, Mutat. Res. 6, 371-385.
27. Rupp, W. D., and Howard-Flanders, P. (1968) Discontinuities in the DNA synthesized in excision-deficient-strain of Escherichia coli following ultraviolet irradiation, J. Mol. Biol. 31, 291-304.
28. Franklin, W. A., and Haseltine, W. A. (1984) Removal of UV-light-induced pyrimidine-pyrimidone (6-4) photoproducts from Escherichia coli requires the uvrA, uvrB, and uvrC gene products, Proc. Natl. Acad. Sci. U.S.A. 81, 3821-3824.
29. Brash, D. E., Franklin, W. A., Sancar, G. B., Sancar, A., and Haseltine, W. A. (1985) E. coli photolyase reverses cyclobutane pyrimidine dimers but not pyrmidine-phrmidone (6-4) photoproducts, J. Biol. Chem. 260, 11438-11441.
30. Fontecave, M., Eliasson, R., and Reichard, P. (1987) NAD(P)H: flavin oxidoreductase of Escherichia coli, J. Biol. Chem. 262, 12325-12331.
31. 2 by NAD(P)H-flavin oxidoreductase and 4-hydroxyphenylacetate 3-monooxygenase, Biochemistry 42, 7509-7517.
32. Coves, J., Niviere, V., Eschenbrenner, M., and Fontecave, M. (1993) NADPH-sulfite reductase from Escherichia coli, J. Biol. Chem. 268, 18604-18609.
33. Heelis, P. F., Okamura, T., and Sancar, A. (1990) Excited-state properties of E. coli photolyase in the picosecond to millisecond time scale. Biochemistry 29, 5698-5706.