A stereochemical anomaly: The cyclised (R)-AMPA analogue (R)-3-hydroxy-4,5,6,7-tetrahydroisoxazolo[5,4-c]pyridine-5-carboxylic acid [(R)-5-HPCA] resembles (S)-AMPA at glutamate receptors

Organic and Biomolecular Chemistry

Volumn 2, Issue 2, 2004, Pages 206-213

  Vogensen, Stine B ^a   Greenwood, Jeremy R ^a   Varming, Annemarie R ^a   Brehm, Lotte ^a   Pickering, Darryl S ^a   Nielsen, Birgitte ^a   Liljefors, Tommy ^a   Clausen, Rasmus P ^a   Johansen, Tommy N ^a   Krogsgaard Larsen, Povl ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACIDS; CHROMATOGRAPHIC ANALYSIS; CONFORMATIONS; CRYSTALLIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SOLVENTS; SYNTHESIS (CHEMICAL); X RAY ANALYSIS;

ELECTRONIC CIRCULAR DICHROISM SPECTRA; ENANTIOMERS; PHARMOCOLOGICAL EFFECTS; STEREOSELECTIVITY;

STEREOCHEMISTRY;

FELIS CATUS;

2 AMINO 4 PHOSPHONOMETHYL 3 HEPTENOIC ACID; 2 AMINO 5 PHOSPHONOVALERIC ACID; ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; AMPA RECEPTOR; DRUG DERIVATIVE; ISOXAZOLE DERIVATIVE; KAINIC ACID RECEPTOR;

ANIMAL; ARTICLE; CHEMICAL STRUCTURE; CHEMISTRY; CIRCULAR DICHROISM; COMPARATIVE STUDY; CONFORMATION; CYCLIZATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLISM; METHODOLOGY; RADIOASSAY; RAT; STEREOISOMERISM; SYNTHESIS; X RAY CRYSTALLOGRAPHY;

2-AMINO-5-PHOSPHONOVALERATE; ALPHA-AMINO-3-HYDROXY-5-METHYL-4-ISOXAZOLEPROPIONIC ACID; ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CIRCULAR DICHROISM; CRYSTALLOGRAPHY, X-RAY; CYCLIZATION; ISOXAZOLES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; RADIOLIGAND ASSAY; RATS; RECEPTORS, AMPA; RECEPTORS, KAINIC ACID; STEREOISOMERISM;

EID: 0942290249     PISSN: 14770520     EISSN: None     Source Type: Journal    
DOI: 10.1039/b310450h     Document Type: Article

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