Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for enhanced survival of transplanted oligodendrocyte progenitors in X-irradiated compared to normal CNS

Neuropathology and Applied Neurobiology

Volumn 27, Issue 1, 2001, Pages 59-67

  Hinks, G L ^a   Chari, D M ^a   O'Leary, M T ^a   Zhao, C ^a   Keirstead, H S ^a   Blakemore, W F ^a   Franklin, R J M ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Blood brain barrier; Growth factor; Migration; Oligodendrocyte progenitor; Transplantation; X irradiation

Indexed keywords

CILIARY NEUROTROPHIC FACTOR; GROWTH FACTOR; MESSENGER RNA; NEURITE PROMOTING FACTOR; NEUROTROPHIN 3; PLATELET DERIVED GROWTH FACTOR A; PLATELET DERIVED GROWTH FACTOR RECEPTOR; SOMATOMEDIN C;

ADOLESCENT; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN RADIATION; CELL LOSS; CELL MIGRATION; CELL SURVIVAL; CELL TRANSPLANTATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IN SITU HYBRIDIZATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; RAT; STEM CELL; X IRRADIATION;

ANIMALS; ANTIGENS; BLOOD-BRAIN BARRIER; BRAIN TISSUE TRANSPLANTATION; CELL COUNT; CELL SURVIVAL; CENTRAL NERVOUS SYSTEM; CILIARY NEUROTROPHIC FACTOR; FEMALE; GRAFT SURVIVAL; GROWTH SUBSTANCES; IN SITU HYBRIDIZATION; INSULIN-LIKE GROWTH FACTOR I; MYELIN BASIC PROTEINS; NERVE TISSUE PROTEINS; NEUREGULIN-1; NEUROTROPHIN 3; OLIGODENDROGLIA; PLATELET-DERIVED GROWTH FACTOR; PROTEOGLYCANS; RATS; RATS, INBRED STRAINS; RATS, SPRAGUE-DAWLEY; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR ALPHA; RNA, MESSENGER; SPINAL CORD; STEM CELL TRANSPLANTATION; STEM CELLS;

EID: 0035067332     PISSN: 03051846     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.0305-1846.2001.00303.x     Document Type: Article

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