Cytokine-induced selective increase of high-molecular-weight bFGF isoforms and their subcellular kinetics in cultured rat hippocampal astrocytes

Neurochemical Research

Volumn 21, Issue 6, 1996, Pages 701-706

  Kamiguchi, Hiroyuki ^a   Yoshida, Kazunari ^a   Wakamoto, Hirooki ^a   Inaba, Makoto ^a   Sasaki, Hikaru ^a   Otani, Mitsuhiro ^a   Toya, Shigeo ^a  

^a KEIO UNIVERSITY   (Japan)

Author keywords

astrocyte; Basic fibroblast growth factor; epidermal growth factor; interleukin 1 ; isoform; tumor necrosis factor

Indexed keywords

BASIC FIBROBLAST GROWTH FACTOR; CYTOKINE; EPIDERMAL GROWTH FACTOR; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN INJURY; GENE EXPRESSION; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOBLOTTING; IMMUNOFLUORESCENCE TEST; NERVE CELL LESION; NONHUMAN; PRIORITY JOURNAL; RAT; RNA TRANSCRIPTION; TRANSLATION INITIATION;

ANIMALS; ASTROCYTES; CELLS, CULTURED; CYTOKINES; FIBROBLAST GROWTH FACTOR 2; HIPPOCAMPUS; KINETICS; MOLECULAR WEIGHT; RATS; RATS, WISTAR; SUBCELLULAR FRACTIONS;

EID: 0029894174     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF02527728     Document Type: Article

References (30)

1. Gospodarowicz, D., Cheng, J., Lui, G. M., Baird, A., and Bohlen, P. 1984. Isolation of brain fibroblast growth factor by heparin-sepharose affinity chromatography: identity with pituitary fibroblast growth factor. Proc. Natl. Acad. Sci. USA 81:6963-6967.
2. Moscatelli, D., Joseph-Silverstein, J., Manejias, R., and Rifkin, D. B. 1987. Mr 25,000 heparin-binding protein from guinea pig brain is a high molecular weight form of basic fibroblast growth factor. Proc. Natl. Acad. Sci. USA 84:5778-5782.
3. Sommer, A., Brewer, M. T., Thompson, R. C., Moscatelli, D., Presta, M., and Rifkin, D. B. 1987. A form of human basic fibroblast growth factor with an extended amino terminus. Biochem. Biophys. Res. Commun. 144:543-550.
4. Florkiewicz, R. Z., and Sommer, A. 1989. Human basic fibroblast growth factor gene encodes four polypeptides: Three initiate translation from non-AUG codons. Proc. Natl. Acad. Sci. USA 86: 3978-3981.
5. Prats, H., Kaghad, M., Prats, A. C., Klagsbrun, M., Lelias, J. M., Liauzun, P., Chalon, P., Tauber, J. P., Amalric, F., Smith, J. A., and Caput, D. 1989. High molecular mass forms of basic fibroblast growth factor are initiated by alternative CUG codons. Proc. Natl. Acad. Sci. USA 86:1836-1840.
6. Renko, M., Quarto, N., Morimoto, T., and Rifkin, D. B. 1990. Nuclear and cytoplasmic localization of different basic fibroblast growth factor species. J. Cell Physiol. 144:108-114.
7. Bugler, B., Amalric, F., and Prats, H. 1991. Alternative initiation of translation determines cytoplasmic or nuclear localization of basic fibroblast growth factor. Mol. Cell. Biol. 11:573-577.
8. Quarto, N., Talarico, D., Florkiewicz, R., and Rifkin, D. B. 1991. Selective expression of high molecular weight basic fibroblast growth factor confers a unique phenotype to NIH 3T3 cells. Cell Regul. 2:699-708.
9. Anderson, K. J., Dam, D., Lee, S., and Cotman, C. W. 1988. Basic fibroblast growth factor prevents death of lesioned cholinergic neurons in vivo. Nature 332:360-361.
10. Grothe, C., and Unsicker, K. 1992. Basic fibroblast growth factor in the hypoglossal system: Specific retrograde transport, trophic, and lesion-related responses. J. Neurosci. Res. 32:317-328.
11. Otto, D., and Unsicker, K. 1990. Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. J. Neurosci. 10:1912-1921.
12. Finkelstein, S. P., Apostolides, P. J., Caday, C. G., Prosser, J., Philips, M. F., and Klagsbrun, M. 1988. Increased basic fibroblast growth factor (bFGF) immunoreactivity at the site of focal brain wounds. Brain Res. 460:253-259.
13. Gomez-Pinilla, F., Lee, J. W.-K., and Cotman, C. W. 1992. Basic FGF in adult rat brain: Cellular distribution and response to entorhinal lesion and fimbria-fornix transection. J. Neurosci., 12: 345-355.
14. Nieto-Sampedro, M., and Herman, M. A. 1987. Interleukin-1-like activity in rat brain: sources, targets, and effects of injury. J. Neurosci. Res. 17:214-219.
15. Heiter, E., Ayala, J., Bousseau, A., Denefle, P., and Prochiantz, A. 1990. Amoeboid microglial cells and not astrocytes synthesize TNF-α in Swiss mouse brain cell cultures. Eur. J. Neurosci. 2: 762-768.
16. Yoshida, K., and Gage, F. H. 1991. Fibroblast growth factors stimulate nerve growth factor synthesis and secretion by astrocytes. Brain Res. 538:118-126.
17. Rivera, S., Gold, S. J., and Gall, C. M. 1994. Interleukin-1β increases basic fibroblast growth factor mRNA expression in adult rat brain and organotypic hippocampal cultures. Mol. Brain Res. 27:12-26.
18. Florkiewicz, R. Z., Baird, A., and Gonzalez, A. M. 1991. Multiple forms of bFGF: Differential nuclear and cell surface localization. Growth Factors 4:265-275.
19. 2-terminal extension of high molecular weight bFGF is a nuclear targeting signal. J. Cell. Physiol. 147:311-318.
20. Hetier, E., Ayala, J., Denefle, P., Bousseau, A., Rouget, P., Mallat, M., and Prochiantz, A. 1988. Brain macrophages synthesize interleukin-1 and interleukin-1 mRNAs in vitro. J. Neurosci. Res. 21:391-397.
21. Byyny, R. L., Orth, D. N., Cohen, S., and Doyne, E. S. 1974. Epidermal growth factor: effects of androgens and adrenergic agents. Endocrinology 95:776-782.
22. Hirata, Y., Uchihashi, M., Nakajima, H., Fujita, T., and Matsukura, S. 1982. Presence of human epidermal growth factor in human cerebrospinal fluid. J. Clin. Endocrinol. Metab. 55:1174-1177.
23. Spranger, M., Lindholm, D., Bandtlow, C., Heumann, R., Gnahn, H., Naher-Noe, M., and Thoenen, H. 1990. Regulation of nerve growth factor (NGF) synthesis in the rat central nervous system: Comparison between the effects of interleukin-1 and various growth factors in astrocyte cultures and in vivo. Eur. J. Neurosci. 2:69-76.
24. Yoshida, K., and Gage, F. H. 1992. Cooperative regulation of nerve growth factor synthesis and secretion in fibroblasts and astrocytes by fibroblast growth factor and other cytokines. Brain Res. 569:14-25.
25. Yoshida, K., Kakihana, M., Chen, L. S., Ong, M., Baird, A., and Gage, F. H. 1992. Cytokine regulation of nerve growth factor-mediated cholinergic neurotrophic activity synthesized by astrocytes and fibroblasts. J. Neurochem. 59:919-931.
26. Kamiguchi, H., Yoshida, K., Sagoh, M., Sasaki, H., Inaba, M., Wakamoto, H., Otani, M., and Toya, S. 1995. Release of ciliary neurotrophic factor from cultured astrocytes and its modulation by cytokines. Neurochem. Res. 20:1187-1193.
27. Rogelj, S., Weinberg, R. A., Fanning, P., and Klagsbrun, M. 1988. Basic fibroblast growth factor fused to a signal peptide transforms cells. Nature 331:173-175.
28. Gately, S., Tsanaclis, A. M. C., Takano, S., Klagsbrun, M., and Brem, S. 1995. Cells transfected with the basic fibroblast growth factor gene fused to a signal sequence are invasive in vitro and in situ in the brain. Neurosurgery 36:780-788.
29. Couderc, B., Prats, H., Bayard, F., and Amalric, F. 1991. Potential oncogenic effects of basic fibroblast growth factor requires cooperation between CUG and AUG-initiated forms. Cell Regul. 2: 709-718.
30. Presta, M., Statuto, M., Rusnati, M., Dell'Era, P., and Ragnotti, G. 1989. Characterization of a Mr 25,000 basic fibroblast growth factor form in adult, regenerating, and fetal rat liver. Biochem. Biophys. Res. Commun. 164:1182-1189.