The Contribution of Familial Resemblance to Variation in Circulatory Levels of Tissue Inhibitors of Metalloproteinases and Transforming Growth Factor-β1

Calcified Tissue International

Volumn 74, Issue 1, 2004, Pages 47-54

  Pantsulaia, I ^a,b   Trofimov, S ^a   Kalichman, L ^a   Kobyliansky, E ^a   Livshits, G ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b Georgian Academy of Sciences   (United States)

Author keywords

Genetic correlation; Heritability estimate; TGF 1; TIMP 1; TIMP 2; Variance components

Indexed keywords

TISSUE INHIBITOR OF METALLOPROTEINASE; TISSUE INHIBITOR OF METALLOPROTEINASE 1; TISSUE INHIBITOR OF METALLOPROTEINASE 2; TRANSFORMING GROWTH FACTOR BETA1;

ADULT; AGED; ARTICLE; CORRELATION ANALYSIS; ENVIRONMENTAL FACTOR; ENZYME BLOOD LEVEL; FAMILIAL DISEASE; FEMALE; GENETIC CORRELATION; GENETIC VARIABILITY; HEREDITY; HUMAN; MALE; NORMAL HUMAN; OSTEOARTHRITIS; PRIORITY JOURNAL; VARIANCE;

ADOLESCENT; ADULT; AGED; FEMALE; HAND; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NUCLEAR FAMILY; OSTEOARTHRITIS; PEDIGREE; RURAL POPULATION; RUSSIA; TISSUE INHIBITOR OF METALLOPROTEINASE-1; TISSUE INHIBITOR OF METALLOPROTEINASE-2; TISSUE INHIBITOR OF METALLOPROTEINASES; TRANSFORMING GROWTH FACTOR BETA; VARIATION (GENETICS);

EID: 0842305692     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-003-0046-0     Document Type: Article

References (52)

1. Woessner JF, Nagase H (2000) Matrix metalloproteinases and TIMPs. Oxford University Press, New York
2. Mannello F, Gazzanelli G (2001) Tissue inhibitors of metalloproteinases and programmed cell death: conundrums, controversies and potential implications. Apoptosis 6:479-482
3. Birkedal-Hansen H (1995) Proteolytic remodeling of extracellular matrix. Curr Opin Cell Biol 7:728-735
4. Schmidt-Rohlfing B, Thomson M, Niedhart C, Wirtz DC, Schneider U (2002) Correlation of bone and cartilage markers in the synovial fluid with the degree of osteoarthritis. Rheumatol Int 21:193-199
5. Brew K, Dinakarpandian D, Nagase H (2000) Tissue inhibitors of metalloproteinases: evolution, structure and function. Biochim Biophys Acta 1477:267-283
6. Gomez DE, Alonso DF, Yoshiji H, Thorgeirsson UP (1997) Tissue inhibitors of metalloproteinases: structure, regulation and biological functions. Eur J Cell Biol 74:111-122
7. Fassina G, Ferrari N, Brigati C, Benelli R, Santi L, Noonan DM, Albini A (2000) Tissue inhibitors of metalloproteases: regulation and biological activities. Clin Exp Metastasis 18:111-120
8. Imren S, Kohn D, Shimada H, Blavier L, De Clerck YA (1996) Overexpression of Tissue Inhibitor of Metalloproteinases-2 by retroviral-mediated gene transfer in vivo inhibits tumor growth and invasion. Cancer Res 56:2891-2895
9. Tanaka S, Hamanishi C, Kikuchi H, Fukuda K (1998) Factors related to degradation of articular cartilage in osteoarthritis. Semin Arthritis Rheum 27:392-399
10. Frenkel SR, Saadeh PB, Mehrara BJ, Chin GS, Steinbrech DS, Brent B, Gittes GK, Longaker MT (2000) Transforming growth factor beta superfamily members: role in cartilage modeling. Plast Reconstr Surg 105:980-990
11. Andrew B, Edwards D, Murphy G (2002) Metalloproteinase inhibitors: biological actions and therapeutic opportunities. J Cell Sci 115:3719-3727
12. Nemoto O, Yamada H, Mukaida M, Shimmei M (1996) Stimulation of TIMP-1 production by oncostatin M in human articular cartilage. Arthritis Rheum 39:560-566
13. Rydziel S, Varghese S, Canalis E (1997) Transforming growth factor beta1 inhibits collagenase 3 expression by transcriptional and post-transcriptional mechanisms in osteoblast cultures. J Cell Physiol 170:145-152
14. Frankenberger M, Hauck RW, Frankenberger B, Haussinger K, Maier KL, Heyder J, Ziegler-Heitbrock HW (2001) All trans-retinoic acid selectively down-regulates matrix metalloproteinase-9 (MMP-9) and up-regulates tissue inhibitor of metalloproteinase-1 (TIMP-1) in human bronchoalveolar lavage cells. Mol Med 7:263-270
15. Gunther M, Haubeck HD, van de Leur E, Blaser J, Bender S, Gutgemann I (1994) TGF-β1 regulates tissue inhibitor of metalloproteinase-1 expression in differentiated human articular chondrocytes. Arth Rheum 37:395-405
16. Wang L, Almqvist KF, Veys EM, Verbruggen G (2002) Control of extracellular matrix homeostasis of normal cartilage by a TGF-β autocrine pathway. Validation of flow cytometry as a tool to study chondrocyte metabolism in vitro. Osteoarthritis Cart 10:88-198
17. Lawrence RC, Helmick CG, Arnett FC, Deyo RA, Felson DT, Giannini EH, Heyse SP, Hirsch R, Hochberg MC, Hunder GG, Liang MH, Pillemer SR, Steen VD, Wolfe F (1998) Estimates of the prevalence of arthritis and selected musculoskeletal disorders in the United States. Arthritis Rheum 41:778-799
18. Schlaak JF, Pfers I, Meyer zum, Buschenfelde KH, Marker-Hermann E (1996) Different cytokine profiles in the synovial fluid of patients with osteoarthritis, rheumatoid arthritis and seronegative spondylarthropathies. Clin Exp Rheum 14:155-162
19. Hulth A, Johnell O, Miyazono K, Lindberg L, Heinegard D, Heldin CH (1996) Effect of transforming growth factor-β and platelet-derived growth factor-BB on articular cartilage in rats. J Orthop Res 14:547-553
20. van Beuningen HM, Glansbeek HL, van der Kraan PM, van den Berg WB (2000) Osteoarthritis-like changes in the murine knee joint resulting from intra-articular transforming growth factor-β injections. Osteoarthritis Cart 8:25-33
21. Bakker AC, van de Loo FA, van Beuningen HM, Sime P, van Lent PL, van der Kraan PM, Richards CD, van den Berg WB (2001) Overexpression of active TGF-β-1 in the murine knee joint: evidence for synovial-layer-dependent chondrosteophyte formation. Osteoarthritis Cart 9:128-136
22. van Beuningen HM, van der Kraan PM, Arntz OJ, van den Berg WB (1994) Transforming growth factor-β-1 stimulates articular chondrocyte proteoglycan synthesis and induces osteophyte formation in the murine knee joint. Lab Invest 71:279-290
23. Glansbeek HL, van Beuningen HM, Vitters EL, van der Kraan PM, van den Berg WB (1998) Stimulation of articular cartilage repair in established arthritis by local administration of transforming growth factor-β into murine knee joints. Lab Invest 78:133-142
24. Hong Y, Pedersen N, Brismar K, Hall K, De Faire U (1996) Quantitative genetic analyses of insulin growth factor-1 (IGF-1), IGF-binding protein-1, and insulin levels in middle-aged and elderly twins. J Clin Endocrinol Metab 81:1791-1797
25. Harris M, Nguen TV, Howard G, Kelly P, Eisman J (1998) Genetic and environmental correlations between formation and bone mineral density: a twin study. Bone 22:141-145
26. Livshits G, Yakovenko K, Kobyliansky E (2000) Quantitative genetic analysis of circulating levels of biochemical markers of bone formation. Am J Med Genet 94:324-331
27. Pantsulaia I, Trofimov S, Kobyliansky E, Livshits G (2002) Genetic and environmental influences on IL-6 and TNF-alpha plasma levels in an apparently healthy general population. Cytokine 19:138-146
28. Livshits G, Kalichman L, Cohen Z, Kobyliansky E (2002) Mode of inheritance of hand osteoarthritis in ethnically homogeneous pedigrees. Hum Biol 74:849-860
29. Kellgren J, Lawrence J (1963) Atlas of standard radiographs: the epidemiology of chronic rheumatism. Blackwell Scientific Publications, Oxford
30. Hirsch R, Lethbridge-Cejku M, Hanson R, Scott W, Reichle R, Plato CC, Tobin JD, Hochberg MC (1998) Familial aggregation of osteoarthritis: data from the Baltimore Longitudinal Study on Aging. Arthritis Rheum 41:1227-1232
31. Felson DT, Couropmitree NN, Chaisson CE, Hannan MT, Zhang Y, McAlindon TE, LaValley M, Levy D, Myers RH (1998) Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis: the Framingham Study. Arthritis Rheum 41:1064-1071
32. Boehnke M, Moll P, Kottke B, Weidman W (1987) Partitioning the variability of fasting plasma glucose levels in pedigrees. Genetic and environmental factors. Am J Epidemiol 4:679-689
33. Falconer DS, Mackay TF (1996) Introduction to quantitative genetics, 4nd ed. Longman, London
34. Lange K, Weeks D, Boehnke M (1988) Program for pedigree analysis: MENDEL, FISHER and dGENE. Genet Epidemiol 5:471-472
35. Kalichman L, Kobyliansky E, Malkin I, Yakovenko K, Livshits G (2003) Search for linkage between hand osteoarthritis and 11q12-13 chromosomal segment. Osteoarthritis Cart 11:561-568
36. Sokal RR, Rohlf FJ (1995) Biometry. Freeman, San Francisco, p 887
37. Ishiguro N, Ito T, Ito H, Iwata H, Jugessur H, Ionescu M, Poole AR (1999) Relationship of matrix metalloproteinases and their inhibitors to cartilage proteoglycan and collagen turnover: analyses of synovial fluid from patients with osteoarthritis. Arthritis Rheum 42:129-136
38. Kanyama M, Kuboki T, Kojima S, Fujisawa T, Hattori T, Takigawa M, Yamashita A (2000) Matrix metalloproteinases and tissue inhibitors of metalloproteinases in synovial fluids of patients with temporomandibular joint osteoarthritis. Orofac Pain 14:20-30
39. Klimiuk PA, Sierakowski S, Latosiewicz R, Cylwik B, Skowronski J, Chwiecko J (2002) Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in different histological variants of rheumatoid synovitis. Rheumatology 41:78-87
40. Hui W, Rowan AD, Cawston T (2001) Modulation of the expression of matrix metalloproteinase and tissue inhibitors of metalloproteinases by TGF-beta1 and IGF-1 in primary human articular and bovine nasal chondrocytes stimulated with TNF-alpha. Cytokine 16:31-35
41. Naito K, Takahashi M, Kushida K, Suzuki M, Ohishi T, Miura M, Inoue T, Nagano A (1999) Measurement of matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases-1 (TIMP-1) in patients with knee osteoarthritis: comparison with generalized osteoarthritis. Rheumatology 38:510-515
42. Chevalier X, Conrozier T, Gehrmann M, Claudepierre P, Mathieu P, Unger S, Vignon E (2001) Tissue inhibitor of metalloprotease-1 (TIMP-1) serum level may predict progression of hip osteoarthritis. Osteoarthritis Cart 9:300-307
43. Newman B, Wallis GA (2002) Is osteoarthritis a genetic disease? Clin Invest Med 25:139-149
44. Bijkerk C, Houwing-Duistermaat JJ, Valkenburg HA, Meulenbelt I, Hofman A, Breedveld FC, Pols HA, van Duijn CM, Slagboom PE (1999) Heritabilities of radiologic osteoarthritis in peripheral joints and of disc degeneration of the spine. Arthritis Rheum 42:1729-1735
45. Livshits G, Karasik D, Seibel MJ (1999) Statistical genetic analysis of plasma levels of vitamin D: familial study. Ann Hum Genet 63:429-439
46. Otremski I, Karasik D, Livshits G (2000) Genetic variation and covariation of parathyroid hormone levels and bone density in human population. Calcif Tissue Int 66:168-175
47. Hunter DJ, de Lange M, Andrew T, Snieder H, MacGregor AJ, Swaminathan R, Thakker RV, Spector TD (2001) Genetic contribution to bone metabolism, calcium excretion and vitamin D and parathyroid hormone regulation. J Bone Miner Res 16:371-378
48. Tokita A, Kelly PJ, Nguyen TV, Qi JC, Morrison NA, Risteli L, Risteli J, Sambrook PN, Eisman JA (1994) Genetic influences on type I collagen synthesis and degradation: further evidence for genetic regulation of bone turnover. J Clin Endocrinol Metab 78:1461-1466
49. Grainger DJ, Heathcote K, Chiano M, Snieder H, Kemp PR, Metcalfe JC, Carter ND, Spector TD (1999) Genetic control of the circulating concentration of transforming growth factor type beta 1. Hum Mol Genet 8:93-97
50. Willard HF, Durfy SJ, Mahtani MM, Dorkins H, Davies KE, Williams BG (1989) Regional localization of the TIMP gene on the human X chromosome: extension of a conserved synteny and linkage group on proximal Xp. Hum Genet 81:234-238
51. De Clerck Y, Szpirer C, Aly MS, Cassiman JJ, Eeckhout Y, Rousseau G (1992) The gene for tissue inhibitor of metalloproteinases-2 is localized on human chromosome arm 17q25. Genomics 14:782-784
52. Anderson CL, Brown CJ (1999) Polymorphic X-chromosome inactivation of the human TIMP1 gene. Am J Hum Genet 65:699-708