Evidence for a Mendelian gene in a segregation analysis of generalized radiographic osteoarthritis: The Framingham Study

Arthritis and Rheumatism

Volumn 41, Issue 6, 1998, Pages 1064-1071

  Felson, David T ^a   Couropmitree, Nat N ^a   Chaisson, Christine E ^a   Hannan, Marian T ^a   Zhang, Yuqing ^a   Mcalindon, Timothy E ^a   Lavalley, Michael ^a   Levy, Daniel ^b   Myers, Richard H ^a  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CONTROLLED STUDY; ENVIRONMENTAL FACTOR; FEMALE; HAND RADIOGRAPHY; HERITABILITY; HUMAN; INHERITANCE; KNEE RADIOGRAPHY; MAJOR CLINICAL STUDY; MALE; OSTEOARTHRITIS; PRIORITY JOURNAL; RECESSIVE GENE; RISK FACTOR; SCORING SYSTEM; SEGREGATION ANALYSIS; SIBLING;

ADULT; AGED; AGED, 80 AND OVER; ARTHROGRAPHY; FEMALE; GENES, RECESSIVE; HAND; HUMANS; KNEE JOINT; LIKELIHOOD FUNCTIONS; MALE; MIDDLE AGED; MODELS, GENETIC; OSTEOARTHRITIS;

EID: 0031748678     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199806)41:6<1064::AID-ART13>3.0.CO;2-K     Document Type: Article

References (24)

1. Stecher RM. Heberden oration. Heberden's nodes: a clinical description of osteo-arthritis of the finger joints. Ann Rheum Dis 1955;14:1-10.
2. Kellgren JH, Lawrence JS, Bier F. Genetic factors in generalized osteo-arthrosis. Ann Rheum Dis 1963;22:237-54.
3. Lawrence JS, Gelsthorpe K, Morell G. Heberden's nodes and HLA markers in generalized osteoarthritis. J Rheumatol 1983;10 Suppl 9:32-3.
4. Spector TD, Cicuttini F, Baker J, Loughlin J, Hart D. Genetic influences on osteoarthritis in women: a twin study. BMJ 1996; 312:940-4.
5. Ala-Kokko L, Baldwin CT, Moskowitz RW, Prockop DJ. Single base mutation in the type II procollagen gene (COL2A1) as a cause of primary osteoarthritis associated with a mild chondrodysplasia. Proc Natl Acad Sci U S A 1990;87:6565-8.
6. Palotie A, Ott J, Elim K, Cheah K, Vaisanen P, Ryhanen L, et al. Predisposition to familial osteoarthrosis linked to type II collagen gene. Lancet 1989;i:924-7.
7. Vikkula M, Palotie A, Ritvaniemi P, Ott J, Ala-okko L, Sievers U, et al. Early-onset osteoarthritis linked to the type II procollagen gene: detailed clinical phenotype and further analysis of the gene. Arthritis Rheum 1993;36:401-9.
8. Felson DT, Naimark A, Anderson J, Kazis L, Castelli W, Meenan RF. The prevalence of knee osteoarthritis in the elderly: the Framingham Knee Osteoarthritis Study. Arthritis Rheum 1987;30: 914-8.
9. Felson DT, Zhang Y, Hannan MT, Naimark A, Weissman BN, Aliabadi P, et al. The incidence and natural history of knee osteoarthritis in the elderly: the Framingham Osteoarthritis Study. Arthritis Rheum 1995;38:1500-5.
10. Kellgren JH, Lawrence JS. Atlas of standard radiographs: the epidemiology of chronic rheumatism. Vol. 2. Oxford: Blackwell Scientific Publications; 1963.
11. Chaisson CE, Zhang Y, McAlindon TE, Hannan MT, Aliabadi P, Naimark A, et al. Radiographic hand osteoarthritis: incidence, patterns, and influence of pre-existing disease in a populationbased sample. J Rheumatol 1997;24:1337-43.
12. Kannel WB, Sorlie PD. Some health benefits of physical activity: the Framingham Study. Arch Intern Med 1979;139:857-61.
13. Lane NE, Block DA, Jones HH, Simpson U, Fries JF. Osteoarthritis in the hand: a comparison of handedness and hand use. J Rheumatol 1989;16:637-42.
14. SAGE. Statistical analysis for genetic epidemiology, release 2.2. New Orleans: Department of Biometry and Genetics, Louisiana State University Medical Center; 1994.
15. Bonney GE. Regressive logistic models for familial disease and other binary traits. Biometrics 1986;42:611-25.
16. Box GEP, Cox DR. An analysis of transformations (with discussion). J R Statist Soc B 1964;26:211-52.
17. Akaike H. A new look at the statistical model identification. IEEE Trans Automatic Control 1974;AC-19:719-23.
18. Kaprio J, Kujala U, Peltonen L, Koskenvuo M. Genetic liability to osteoarthritis may be greater in women than men [letter]. BMJ 1996;313:232.
19. Cooper C, Egger P, Coggon D, Hart DJ, Masud T, Cicuttini F, et al. Generalized osteoarthritis in women: pattern of joint involvement and approaches to definition for epidemiological studies. J Rheumatol 1996;23:1938-42.
20. Felson DT. Epidemiology of hip and knee osteoarthritis. Epidemiol Rev 1988;10:1-28.
21. Loughlin J, Irven C, Fergusson C, Sykes B. Sibling pair analysis shows no linkage of generalized osteoarthritis to the loci encoding type II collagen, cartilage link protein or cartilage matrix protein. Br J Rheumatol 1994;33:1103-6.
22. Ritvaniemi P, Körkkö J, Bonaventure J, Vikkula M, Hyland J, Paassilta P, et al. Identification of COL2A1 gene mutations in patients with chondrodysplasias and familial osteourthritis. Arthritis Rheum 1995;38:999-1004.
23. Ayral X, Dougados M, Listrat V, Bonvarlet JP, Simonnet J, Amor B. Arthroscopic evaluation of chondropathy in osteoarthritis of the knee. J Rheumatol 1996;23:698-706.
24. Buckland-Wright JC, Macfarlane DG, Lynch JA, Jasani MK, Bradshaw CR. Joint space width measures cartilage thickness in osteoarthritis of the knee: high resolution plain film and double contrast macroradiographic investigation. Ann Rheum Dis 1995; 54:263-8.