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Volumn 32, Issue 1, 2004, Pages 3-17

Polycystic ovary syndrome in pubertal period: Clinical, biological, metabolic and genetic polymorphism;Le syndrome des ovaires polykystiques en période péri-pubertaire: Polymorphisme clinique, biologique, métabolique et génétique

Author keywords

Adolescent; Hyperandrogenism; Polycystic ovary syndrome; Puberty

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; ANTIANDROGEN; CALPAIN; CYPROTERONE ACETATE; CYTOCHROME P450 17; FOLLISTATIN; FOLLITROPIN; FOLLITROPIN RECEPTOR; GLUCOCORTICOID; INSULIN; INSULIN RECEPTOR; RESISTIN; SEX HORMONE BINDING GLOBULIN; TESTOSTERONE;

EID: 0842281701     PISSN: 12979589     EISSN: 17696682     Source Type: Journal    
DOI: 10.1016/j.gyobfe.2003.10.027     Document Type: Short Survey
Times cited : (12)

References (113)
  • 3
    • 0034934113 scopus 로고    scopus 로고
    • Menstrual irregularity in the first postmenarchal years: An early clinical sign of polycystic ovary syndrome in adolescence
    • Avvad C.K., Holeuwerger R., Silva V.C., Bordallo M.A., Breitenbach M.M. Menstrual irregularity in the first postmenarchal years: an early clinical sign of polycystic ovary syndrome in adolescence. Gynecol Endocrinol. 15:(3):2001 Jun;170-177.
    • (2001) Gynecol Endocrinol , vol.15 , Issue.3 , pp. 170-177
    • Avvad, C.K.1    Holeuwerger, R.2    Silva, V.C.3    Bordallo, M.A.4    Breitenbach, M.M.5
  • 4
    • 0033587746 scopus 로고    scopus 로고
    • Thirty-seven candidate genes for polycystic ovary syndrome: Strongest evidence for linkage is with follistatin
    • Urbanek M., Legro R.S., Driscoll D.A., Azziz R., Ehrmann D.A., Norman R.J., et al. Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin. Proc Natl Acad Sci USA. 96:(15):1999 Jul 20;8573-8578.
    • (1999) Proc Natl Acad Sci USA , vol.96 , Issue.15 JUL 20 , pp. 8573-8578
    • Urbanek, M.1    Legro, R.S.2    Driscoll, D.A.3    Azziz, R.4    Ehrmann, D.A.5    Norman, R.J.6
  • 5
    • 0029095150 scopus 로고
    • Polycystic ovary syndrome
    • Review
    • Franks S. Polycystic ovary syndrome. N Engl J Med. 333:(13):1995 Sep 28;853-861. Review.
    • (1995) N Engl J Med. , vol.333 , Issue.13 SEP 28 , pp. 853-861
    • Franks, S.1
  • 6
    • 0001698606 scopus 로고
    • Amenorrhea associated with bilateral polycystic ovaries
    • Stein I.F., Leventhal M.L. Amenorrhea associated with bilateral polycystic ovaries. Am J Obstet Gynecol. 29:1935;181-191.
    • (1935) Am J Obstet Gynecol , vol.29 , pp. 181-191
    • Stein, I.F.1    Leventhal, M.L.2
  • 7
    • 0028044645 scopus 로고
    • The prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women
    • Farquhar C.M., Birdsall M., Manning P., Mitchell J.M., France J.T. The prevalence of polycystic ovaries on ultrasound scanning in a population of randomly selected women. Aust N Z J Obstet Gynaecol. 34:(1):1994 Feb;67-72.
    • (1994) Aust N Z J Obstet Gynaecol , vol.34 , Issue.1 , pp. 67-72
    • Farquhar, C.M.1    Birdsall, M.2    Manning, P.3    Mitchell, J.M.4    France, J.T.5
  • 8
    • 0006145215 scopus 로고
    • Androgens in infancy, childhood and adolescence
    • Redmond G.P. Raven Press
    • Lee P.A., Siegel S.W. Androgens in infancy, childhood and adolescence. Redmond G.P. « Androgenic disorders » 1995;59-76 Raven Press.
    • (1995) « Androgenic Disorders » , pp. 59-76
    • Lee, P.A.1    Siegel, S.W.2
  • 9
    • 0017724145 scopus 로고
    • Gray-scale ultrasonography of the normal female pelvis
    • Sample W.F., Lippe B.M., Gyepes M.T. Gray-scale ultrasonography of the normal female pelvis. Radiology. 125:(2):1977 Nov;477-483.
    • (1977) Radiology , vol.125 , Issue.2 , pp. 477-483
    • Sample, W.F.1    Lippe, B.M.2    Gyepes, M.T.3
  • 10
    • 0020528216 scopus 로고
    • Ultrasonography of the pelvic organs in prepubertal and postpubertal girls
    • Ivarsson S.A., Nilsson K.O., Persson P.H. Ultrasonography of the pelvic organs in prepubertal and postpubertal girls. Arch Dis Child. 58:(5):1983 May;352-354.
    • (1983) Arch Dis Child , vol.58 , Issue.5 , pp. 352-354
    • Ivarsson, S.A.1    Nilsson, K.O.2    Persson, P.H.3
  • 12
    • 0033917404 scopus 로고    scopus 로고
    • Polycystic ovaries in adolescents and the relationship with menstrual cycle patterns, luteinizing hormone, androgens, and insulin
    • Van Hooff M.H., Voorhorst F.J., Kaptein M.B., Hirasing R.A., Koppenaal C., Schoemaker J. Polycystic ovaries in adolescents and the relationship with menstrual cycle patterns, luteinizing hormone, androgens, and insulin. Fertil Steril. 74:(1):2000 Jul;49-58.
    • (2000) Fertil Steril , vol.74 , Issue.1 , pp. 49-58
    • Van Hooff, M.H.1    Voorhorst, F.J.2    Kaptein, M.B.3    Hirasing, R.A.4    Koppenaal, C.5    Schoemaker, J.6
  • 13
    • 0026813890 scopus 로고
    • Premature adrenarche: A normal variant of puberty?
    • Saenger P., Reiter E.O. Premature adrenarche: a normal variant of puberty? J Clin Endocrinol Metab. 74:(2):1992 Feb;236-238.
    • (1992) J Clin Endocrinol Metab , vol.74 , Issue.2 , pp. 236-238
    • Saenger, P.1    Reiter, E.O.2
  • 14
    • 0017155794 scopus 로고
    • Evidence for the adrenal source of androgens in precocious adrenarche
    • Korth-Schutz S., Levine L.S., New M.I. Evidence for the adrenal source of androgens in precocious adrenarche. Acta Endocrinol (Copenh). 82:(2):1976 Jun;342-352.
    • (1976) Acta Endocrinol (Copenh) , vol.82 , Issue.2 , pp. 342-352
    • Korth-Schutz, S.1    Levine, L.S.2    New, M.I.3
  • 15
    • 0015107694 scopus 로고
    • Plasma 17-ketosteroids and 17-beta hydroxysteroids in girls with premature development of sexual hair
    • Rosenfield R.L. Plasma 17-ketosteroids and 17-beta hydroxysteroids in girls with premature development of sexual hair. J Pediatr. 79:1971;260-266.
    • (1971) J Pediatr , vol.79 , pp. 260-266
    • Rosenfield, R.L.1
  • 16
    • 0025057671 scopus 로고
    • Adrenal steroidogenic function in a black and Hispanic population with precocious pubarche
    • Oberfield S.E., Mayes D.M., Levine L.S. Adrenal steroidogenic function in a black and Hispanic population with precocious pubarche. J Clin Endocrinol Metab. 70:(1):1990 Jan;76-82.
    • (1990) J Clin Endocrinol Metab , vol.70 , Issue.1 , pp. 76-82
    • Oberfield, S.E.1    Mayes, D.M.2    Levine, L.S.3
  • 17
    • 0027166906 scopus 로고
    • Postpubertal outcome in girls diagnosed of premature pubarche during childhood: Increased frequency of functional ovarian hyperandrogenism
    • Ibanez L., Potau N., Virdis R., Zampolli M., Terzi C., Gussinye M., et al. Postpubertal outcome in girls diagnosed of premature pubarche during childhood: increased frequency of functional ovarian hyperandrogenism. J Clin Endocrinol Metab. 76:(6):1993 Jun;1599-1603.
    • (1993) J Clin Endocrinol Metab , vol.76 , Issue.6 , pp. 1599-1603
    • Ibanez, L.1    Potau, N.2    Virdis, R.3    Zampolli, M.4    Terzi, C.5    Gussinye, M.6
  • 18
    • 0036316967 scopus 로고    scopus 로고
    • Isolated premature pubarche: Ultrasonographic and color Doppler analysis - A longitudinal study
    • Battaglia C., Regnani G., Mancini F., Iughetti L., Bernasconi S., Volpe A., et al. Isolated premature pubarche: ultrasonographic and color Doppler analysis - a longitudinal study. J Clin Endocrinol Metab. 87:(7):2002 Jul;3148-3154.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.7 , pp. 3148-3154
    • Battaglia, C.1    Regnani, G.2    Mancini, F.3    Iughetti, L.4    Bernasconi, S.5    Volpe, A.6
  • 19
    • 0033668039 scopus 로고    scopus 로고
    • Sex hormone-binding globulin during puberty in normal and hyperandrogenic girls
    • Pugeat M., Cousin P., Baret C., Lejeune H., Forest M.G. Sex hormone-binding globulin during puberty in normal and hyperandrogenic girls. J Pediatr Endocrinol Metab. 13:(Suppl 5):2000;1277-1279.
    • (2000) J Pediatr Endocrinol Metab , vol.13 , Issue.SUPPL. 5 , pp. 1277-1279
    • Pugeat, M.1    Cousin, P.2    Baret, C.3    Lejeune, H.4    Forest, M.G.5
  • 21
    • 0033507631 scopus 로고    scopus 로고
    • Aspects of ovarian follicle development throughout life
    • Macklon N.S., Fauser B.C. Aspects of ovarian follicle development throughout life. Horm Res. 52:(4):1999;161-170.
    • (1999) Horm Res , vol.52 , Issue.4 , pp. 161-170
    • MacKlon, N.S.1    Fauser, B.C.2
  • 22
    • 0036313064 scopus 로고    scopus 로고
    • Developmental origin of polycystic ovary syndrome - A hypothesis
    • Abbott D.H., Dumesic D.A., Franks S. Developmental origin of polycystic ovary syndrome - a hypothesis. J Endocrinol. 174:(1):2002 Jul;1-5.
    • (2002) J Endocrinol , vol.174 , Issue.1 , pp. 1-5
    • Abbott, D.H.1    Dumesic, D.A.2    Franks, S.3
  • 23
    • 0029863969 scopus 로고    scopus 로고
    • Hyperinsulinemia in postpubertal girls with a history of premature pubarche and functional ovarian hyperandrogenism
    • Ibanez L., Potau N., Zampolli M., Prat N., Virdis R., Vicens-Calvet E., et al. Hyperinsulinemia in postpubertal girls with a history of premature pubarche and functional ovarian hyperandrogenism. J Clin Endocrinol Metab. 81:(3):1996 Mar;1237-1243.
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.3 , pp. 1237-1243
    • Ibanez, L.1    Potau, N.2    Zampolli, M.3    Prat, N.4    Virdis, R.5    Vicens-Calvet, E.6
  • 25
    • 0031769471 scopus 로고    scopus 로고
    • Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: Relation to reduced fetal growth
    • Ibanez L., Potau N., Francois I., de Zegher F. Precocious pubarche, hyperinsulinism, and ovarian hyperandrogenism in girls: relation to reduced fetal growth. J Clin Endocrinol Metab. 83:(10):1998 Oct;3558-3562.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.10 , pp. 3558-3562
    • Ibanez, L.1    Potau, N.2    Francois, I.3    De Zegher, F.4
  • 26
    • 0036152665 scopus 로고    scopus 로고
    • Plasminogen activator inhibitor-1 in girls with precocious pubarche: A premenarcheal marker for polycystic ovary syndrome?
    • Ibanez L., Aulesa C., Potau N., Ong K., Dunger D.B., de Zegher F. Plasminogen activator inhibitor-1 in girls with precocious pubarche: a premenarcheal marker for polycystic ovary syndrome? Pediatr Res. 51:(2):2002 Feb;244-248.
    • (2002) Pediatr Res , vol.51 , Issue.2 , pp. 244-248
    • Ibanez, L.1    Aulesa, C.2    Potau, N.3    Ong, K.4    Dunger, D.B.5    De Zegher, F.6
  • 27
    • 0028356926 scopus 로고
    • Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: Relevance to the developmental phase of polycystic ovarian syndrome
    • Apter D., Butzow T., Laughlin G.A., Yen S.S. Accelerated 24-hour luteinizing hormone pulsatile activity in adolescent girls with ovarian hyperandrogenism: relevance to the developmental phase of polycystic ovarian syndrome. J Clin Endocrinol Metab. 79:(1):1994 Jul;119-125.
    • (1994) J Clin Endocrinol Metab , vol.79 , Issue.1 , pp. 119-125
    • Apter, D.1    Butzow, T.2    Laughlin, G.A.3    Yen, S.S.4
  • 28
    • 0028827836 scopus 로고
    • High prevalence of abnormal adrenal response in girls with central precocious puberty at early pubertal stages
    • Lazar L., Kauli R., Bruchis C., Nordenberg J., Galatzer A., Pertzelan A. High prevalence of abnormal adrenal response in girls with central precocious puberty at early pubertal stages. Eur J Endocrinol. 133:(4):1995 Oct;407-411.
    • (1995) Eur J Endocrinol , vol.133 , Issue.4 , pp. 407-411
    • Lazar, L.1    Kauli, R.2    Bruchis, C.3    Nordenberg, J.4    Galatzer, A.5    Pertzelan, A.6
  • 29
    • 0035145810 scopus 로고    scopus 로고
    • Disruption of the joint synchrony of luteinizing hormone, testosterone, and androstenedione secretion in adolescents with polycystic ovarian syndrome
    • Veldhuis J.D., Pincus S.M., Garcia-Rudaz M.C., Ropelato M.G., Escobar M.E., Barontini M. Disruption of the joint synchrony of luteinizing hormone, testosterone, and androstenedione secretion in adolescents with polycystic ovarian syndrome. J Clin Endocrinol Metab. 86:(1):2001 Jan;72-79.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.1 , pp. 72-79
    • Veldhuis, J.D.1    Pincus, S.M.2    Garcia-Rudaz, M.C.3    Ropelato, M.G.4    Escobar, M.E.5    Barontini, M.6
  • 30
    • 0026733789 scopus 로고
    • Ovulation and menstrual function of adolescent girls with central precocious puberty after therapy with gonadotropin-releasing hormone agonists
    • Jay N., Mansfield M.J., Blizzard R.M., Crowley W.F. Jr, Schoenfeld D., Rhubin L., et al. Ovulation and menstrual function of adolescent girls with central precocious puberty after therapy with gonadotropin-releasing hormone agonists. J Clin Endocrinol Metab. 75:(3):1992 Sep;890-894.
    • (1992) J Clin Endocrinol Metab , vol.75 , Issue.3 , pp. 890-894
    • Jay, N.1    Mansfield, M.J.2    Blizzard, R.M.3    Crowley Jr., W.F.4    Schoenfeld, D.5    Rhubin, L.6
  • 32
    • 0023100526 scopus 로고
    • Puberty decreases insulin sensitivity
    • Bloch C.A., Clemons P., Sperling M.A. Puberty decreases insulin sensitivity. J Pediatr. 110:(3):1987 Mar;481-487.
    • (1987) J Pediatr , vol.110 , Issue.3 , pp. 481-487
    • Bloch, C.A.1    Clemons, P.2    Sperling, M.A.3
  • 34
    • 0024437305 scopus 로고
    • Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
    • Dunaif A., Segal K.R., Futterweit W., Dobrjansky A. Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes. 38:(9):1989 Sep;1165-1174.
    • (1989) Diabetes , vol.38 , Issue.9 , pp. 1165-1174
    • Dunaif, A.1    Segal, K.R.2    Futterweit, W.3    Dobrjansky, A.4
  • 35
    • 0028889654 scopus 로고
    • Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism
    • Apter D., Butzow T., Laughlin G.A., Yen S.S. Metabolic features of polycystic ovary syndrome are found in adolescent girls with hyperandrogenism. J Clin Endocrinol Metab. 80:(10):1995 Oct;2966-2973.
    • (1995) J Clin Endocrinol Metab , vol.80 , Issue.10 , pp. 2966-2973
    • Apter, D.1    Butzow, T.2    Laughlin, G.A.3    Yen, S.S.4
  • 36
    • 0030802948 scopus 로고    scopus 로고
    • Hyperinsulinemia and decreased insulin-like growth factor-binding protein-1 are common features in prepubertal and pubertal girls with a history of premature pubarche
    • Ibanez L., Potau N., Zampolli M., Rique S., Saenger P., Carrascosa A. Hyperinsulinemia and decreased insulin-like growth factor-binding protein-1 are common features in prepubertal and pubertal girls with a history of premature pubarche. J Clin Endocrinol Metab. 82:(7):1997 Jul;2283-2288.
    • (1997) J Clin Endocrinol Metab , vol.82 , Issue.7 , pp. 2283-2288
    • Ibanez, L.1    Potau, N.2    Zampolli, M.3    Rique, S.4    Saenger, P.5    Carrascosa, A.6
  • 37
    • 0031787388 scopus 로고    scopus 로고
    • A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome
    • Legro R.S., Finegood D., Dunaif A. A fasting glucose to insulin ratio is a useful measure of insulin sensitivity in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 83:(8):1998 Aug;2694-2698.
    • (1998) J Clin Endocrinol Metab , vol.83 , Issue.8 , pp. 2694-2698
    • Legro, R.S.1    Finegood, D.2    Dunaif, A.3
  • 38
    • 0021813187 scopus 로고
    • Homeostasis model assessment: Insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia. 28:(7):1985 Jul;412-419.
    • (1985) Diabetologia , vol.28 , Issue.7 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 39
    • 0022361971 scopus 로고
    • Assessment of insulin sensitivity in vivo
    • Bergman R.N., Finegood D.T., Ader M. Assessment of insulin sensitivity in vivo. Endocr Rev. 6:(1):1985 Winter;45-86.
    • (1985) Endocr Rev , vol.6 , Issue.1 , pp. 45-86
    • Bergman, R.N.1    Finegood, D.T.2    Ader, M.3
  • 40
    • 0035142971 scopus 로고    scopus 로고
    • Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome
    • Lewy V.D., Danadian K., Witchel S.F., Arslanian S. Early metabolic abnormalities in adolescent girls with polycystic ovarian syndrome. J Pediatr. 138:(1):2001 Jan;38-44.
    • (2001) J Pediatr , vol.138 , Issue.1 , pp. 38-44
    • Lewy, V.D.1    Danadian, K.2    Witchel, S.F.3    Arslanian, S.4
  • 41
    • 0035143773 scopus 로고    scopus 로고
    • Glucose intolerance in obese adolescents with polycystic ovary syndrome: Roles of insulin resistance and beta-cell dysfunction and risk of cardiovascular disease
    • Arslanian S.A., Lewy V.D., Danadian K. Glucose intolerance in obese adolescents with polycystic ovary syndrome: roles of insulin resistance and beta-cell dysfunction and risk of cardiovascular disease. J Clin Endocrinol Metab. 86:(1):2001 Jan;66-71.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.1 , pp. 66-71
    • Arslanian, S.A.1    Lewy, V.D.2    Danadian, K.3
  • 43
    • 0028345924 scopus 로고
    • Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance
    • Holte J., Bergh T., Berne C., Berglund L., Lithell H. Enhanced early insulin response to glucose in relation to insulin resistance in women with polycystic ovary syndrome and normal glucose tolerance. J Clin Endocrinol Metab. 78:(5):1994 May;1052-1058.
    • (1994) J Clin Endocrinol Metab , vol.78 , Issue.5 , pp. 1052-1058
    • Holte, J.1    Bergh, T.2    Berne, C.3    Berglund, L.4    Lithell, H.5
  • 44
    • 0038699027 scopus 로고    scopus 로고
    • The biological variation of testosterone and sex hormone-binding globulin (SHBG) in polycystic ovarian syndrome: Implications for SHBG as a surrogate marker of insulin resistance
    • Jayagopal V., Kilpatrick E.S., Jennings P.E., Hepburn D.A., Atkin S.L. The biological variation of testosterone and sex hormone-binding globulin (SHBG) in polycystic ovarian syndrome: implications for SHBG as a surrogate marker of insulin resistance. J Clin Endocrinol Metab. 88:(4):2003 Apr;1528-1533.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.4 , pp. 1528-1533
    • Jayagopal, V.1    Kilpatrick, E.S.2    Jennings, P.E.3    Hepburn, D.A.4    Atkin, S.L.5
  • 45
    • 0024491337 scopus 로고
    • Association of decreased sex hormone binding globulin and cardiovascular risk factors
    • Haffner S.M., Katz M.S., Stern M.P., Dunn J.F. Association of decreased sex hormone binding globulin and cardiovascular risk factors. Arteriosclerosis. 9:(1):1989 Jan-Feb;136-143.
    • (1989) Arteriosclerosis , vol.9 , Issue.1 , pp. 136-143
    • Haffner, S.M.1    Katz, M.S.2    Stern, M.P.3    Dunn, J.F.4
  • 46
    • 0038369147 scopus 로고    scopus 로고
    • Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome
    • Yildiz B.O., Yarali H., Oguz H., Bayraktar M. Glucose intolerance, insulin resistance, and hyperandrogenemia in first degree relatives of women with polycystic ovary syndrome. J Clin Endocrinol Metab. 88:(5):2003 May;2031-2036.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.5 , pp. 2031-2036
    • Yildiz, B.O.1    Yarali, H.2    Oguz, H.3    Bayraktar, M.4
  • 47
    • 0029124840 scopus 로고
    • The growth hormone response to growth hormone-releasing hormone is blunted in polycystic ovary syndrome: Relationship with obesity and hyperinsulinaemia
    • Lanzone A., Villa P., Fulghesu A.M., Pavone V., Caruso A., Mancuso S. The growth hormone response to growth hormone-releasing hormone is blunted in polycystic ovary syndrome: relationship with obesity and hyperinsulinaemia. Hum Reprod. 10:(7):1995 Jul;1653-1657.
    • (1995) Hum Reprod , vol.10 , Issue.7 , pp. 1653-1657
    • Lanzone, A.1    Villa, P.2    Fulghesu, A.M.3    Pavone, V.4    Caruso, A.5    Mancuso, S.6
  • 48
    • 0038168725 scopus 로고    scopus 로고
    • Insulin and GH secretion in adolescent girls with irregular cycles: Polycystic vs multifollicular ovaries
    • Villa P., Rossodivita A., Fulghesu A.M., Cucinelli F., Barini A., Apa R., et al. Insulin and GH secretion in adolescent girls with irregular cycles: polycystic vs multifollicular ovaries. J Endocrinol Invest. 26:(4):2003 Apr;305-311.
    • (2003) J Endocrinol Invest , vol.26 , Issue.4 , pp. 305-311
    • Villa, P.1    Rossodivita, A.2    Fulghesu, A.M.3    Cucinelli, F.4    Barini, A.5    Apa, R.6
  • 49
    • 0032894725 scopus 로고    scopus 로고
    • Effect of opioid blockade on insulin and growth hormone (GH) secretion in patients with polycystic ovary syndrome: The heterogeneity of impaired GH secretion is related to both obesity and hyperinsulinism
    • Villa P., Valle D., Mancini A., De Marinis L., Pavone V., Fulghesu A.M., Mancuso S., Lanzone A. Effect of opioid blockade on insulin and growth hormone (GH) secretion in patients with polycystic ovary syndrome: the heterogeneity of impaired GH secretion is related to both obesity and hyperinsulinism. Fertil Steril. 71:(1):1999 Jan;115-121.
    • (1999) Fertil Steril , vol.71 , Issue.1 , pp. 115-121
    • Villa, P.1    Valle, D.2    Mancini, A.3    De Marinis, L.4    Pavone, V.5    Fulghesu, A.M.6    Mancuso, S.7    Lanzone, A.8
  • 51
    • 0037203511 scopus 로고    scopus 로고
    • Evidence that chlormadinone acetate exhibits antiandrogenic activity in androgen-dependent cell line
    • Terouanne B., Paris F., Servant N., Georget V., Sultan C. Evidence that chlormadinone acetate exhibits antiandrogenic activity in androgen-dependent cell line. Mol Cell Endocrinol. 198:(1-2):2002 Dec 30;143-147.
    • (2002) Mol Cell Endocrinol , vol.198 , Issue.12 DEC 30 , pp. 143-147
    • Terouanne, B.1    Paris, F.2    Servant, N.3    Georget, V.4    Sultan, C.5
  • 52
    • 0035158107 scopus 로고    scopus 로고
    • Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS
    • Kahsar-Miller M.D., Nixon C., Boots L.R., Go R.C., Azziz R. Prevalence of polycystic ovary syndrome (PCOS) in first-degree relatives of patients with PCOS. Fertil Steril. 75:(1):2001 Jan;53-58.
    • (2001) Fertil Steril , vol.75 , Issue.1 , pp. 53-58
    • Kahsar-Miller, M.D.1    Nixon, C.2    Boots, L.R.3    Go, R.C.4    Azziz, R.5
  • 54
    • 0027196489 scopus 로고
    • Evidence for a single gene effect causing polycystic ovaries and male pattern baldness
    • Carey A.H., Chan K.L., Short F., White D., Williamson R., Franks S. Evidence for a single gene effect causing polycystic ovaries and male pattern baldness. Clin Endocrinol (Oxf). 38:(6):1993 Jun;653-658.
    • (1993) Clin Endocrinol (Oxf) , vol.38 , Issue.6 , pp. 653-658
    • Carey, A.H.1    Chan, K.L.2    Short, F.3    White, D.4    Williamson, R.5    Franks, S.6
  • 55
    • 0032944019 scopus 로고    scopus 로고
    • Polycystic ovaries are inherited as an autosomal dominant trait: Analysis of 29 polycystic ovary syndrome and 10 control families
    • Govind A., Obhrai M.S., Clayton R.N. Polycystic ovaries are inherited as an autosomal dominant trait: analysis of 29 polycystic ovary syndrome and 10 control families. J Clin Endocrinol Metab. 84:(1):1999 Jan;38-43.
    • (1999) J Clin Endocrinol Metab , vol.84 , Issue.1 , pp. 38-43
    • Govind, A.1    Obhrai, M.S.2    Clayton, R.N.3
  • 56
    • 0024241084 scopus 로고
    • Familial polycystic ovarian disease
    • Review
    • Givens J.R. Familial polycystic ovarian disease. Endocrinol Metab Clin North Am. 17:(4):1988 Dec;771-783. Review.
    • (1988) Endocrinol Metab Clin North Am , vol.17 , Issue.4 , pp. 771-783
    • Givens, J.R.1
  • 58
    • 0031049755 scopus 로고    scopus 로고
    • Association of the steroid synthesis gene CYP11a with polycystic ovary syndrome and hyperandrogenism
    • Gharani N., Waterworth D.M., Batty S., White D., Gilling-Smith C., Conway G.S., et al. Association of the steroid synthesis gene CYP11a with polycystic ovary syndrome and hyperandrogenism. Hum Mol Genet. 6:(3):1997 Mar;397-402.
    • (1997) Hum Mol Genet , vol.6 , Issue.3 , pp. 397-402
    • Gharani, N.1    Waterworth, D.M.2    Batty, S.3    White, D.4    Gilling-Smith, C.5    Conway, G.S.6
  • 60
    • 0029796476 scopus 로고    scopus 로고
    • Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome
    • Nestler J.E., Jakubowicz D.J. Decreases in ovarian cytochrome P450c17 alpha activity and serum free testosterone after reduction of insulin secretion in polycystic ovary syndrome. N Engl J Med. 335:(9):1996 Aug 29;617-623.
    • (1996) N Engl J Med , vol.335 , Issue.9 AUG 29 , pp. 617-623
    • Nestler, J.E.1    Jakubowicz, D.J.2
  • 61
    • 0026664328 scopus 로고
    • Detection of functional ovarian hyperandrogenism in women with androgen excess
    • Ehrmann D.A., Rosenfield R.L., Barnes R.B., Brigell D.F., Sheikh Z. Detection of functional ovarian hyperandrogenism in women with androgen excess. N Engl J Med. 327:(3):1992 Jul 16;157-162.
    • (1992) N Engl J Med , vol.327 , Issue.3 JUL 16 , pp. 157-162
    • Ehrmann, D.A.1    Rosenfield, R.L.2    Barnes, R.B.3    Brigell, D.F.4    Sheikh, Z.5
  • 62
    • 0032566950 scopus 로고    scopus 로고
    • Role of cytochrome P450c17 in polycystic ovary syndrome
    • Review
    • Qin K.N., Rosenfield R.L. Role of cytochrome P450c17 in polycystic ovary syndrome. Mol Cell Endocrinol. 145:(1-2):1998 Oct 25;111-121. Review.
    • (1998) Mol Cell Endocrinol , vol.145 , Issue.12 OCT 25 , pp. 111-121
    • Qin, K.N.1    Rosenfield, R.L.2
  • 63
    • 0028024363 scopus 로고
    • Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17
    • Carey A.H., Waterworth D., Patel K., White D., Little J., Novelli P., et al. Polycystic ovaries and premature male pattern baldness are associated with one allele of the steroid metabolism gene CYP17. Hum Mol Genet. 3:(10):1994 Oct;1873-1876.
    • (1994) Hum Mol Genet , vol.3 , Issue.10 , pp. 1873-1876
    • Carey, A.H.1    Waterworth, D.2    Patel, K.3    White, D.4    Little, J.5    Novelli, P.6
  • 65
    • 16044372273 scopus 로고    scopus 로고
    • 5' polymorphism of the CYP17 gene is not associated with serum testosterone levels in women with polycystic ovaries
    • Gharani N., Waterworth D.M., Williamson R., Franks S. 5' polymorphism of the CYP17 gene is not associated with serum testosterone levels in women with polycystic ovaries. J Clin Endocrinol Metab. 81:(11):1996 Nov;4174.
    • (1996) J Clin Endocrinol Metab , vol.81 , Issue.11 , pp. 4174
    • Gharani, N.1    Waterworth, D.M.2    Williamson, R.3    Franks, S.4
  • 66
    • 0034457443 scopus 로고    scopus 로고
    • Differential activity of the cytochrome P450 17alpha-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells
    • Wickenheisser J.K., Quinn P.G., Nelson V.L., Legro R.S., Strauss J.F. 3rd, McAllister J.M. Differential activity of the cytochrome P450 17alpha-hydroxylase and steroidogenic acute regulatory protein gene promoters in normal and polycystic ovary syndrome theca cells. J Clin Endocrinol Metab. 85:(6):2000 Jun;2304-2311.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.6 , pp. 2304-2311
    • Wickenheisser, J.K.1    Quinn, P.G.2    Nelson, V.L.3    Legro, R.S.4    Strauss III, J.F.5    McAllister, J.M.6
  • 67
    • 0038374441 scopus 로고    scopus 로고
    • The molecular phenotype of polycystic ovary syndrome (PCOS) Theca cells and newcandidate PCOS genes defined by microarray analysis
    • Wood J.R., Nelson V.L., Ho C., Jansen E., Wang C.Y., Urbanek M., et al. The molecular phenotype of polycystic ovary syndrome (PCOS) Theca cells and newcandidate PCOS genes defined by microarray analysis. J Biol Chem. 2003 May 6.
    • (2003) J Biol Chem , Issue.MAY 6
    • Wood, J.R.1    Nelson, V.L.2    Ho, C.3    Jansen, E.4    Wang, C.Y.5    Urbanek, M.6
  • 68
    • 0033214141 scopus 로고    scopus 로고
    • The presence of the 21-hydroxylase deficiency carrier status in hirsute women: Phenotype-genotype correlations
    • Escobar-Morreale H.F., San Millan J.L., Smith R.R., Sancho J., Witchel S.F. The presence of the 21-hydroxylase deficiency carrier status in hirsute women: phenotype-genotype correlations. Fertil Steril. 72:(4):1999 Oct;629-638.
    • (1999) Fertil Steril , vol.72 , Issue.4 , pp. 629-638
    • Escobar-Morreale, H.F.1    San Millan, J.L.2    Smith, R.R.3    Sancho, J.4    Witchel, S.F.5
  • 69
    • 0028949603 scopus 로고
    • Molecular abnormalities of the 21-hydroxylase gene in hyperandrogenic women with an exaggerated 17-hydroxyprogesterone response to short-term adrenal stimulation
    • Azziz R., Owerbach D. Molecular abnormalities of the 21-hydroxylase gene in hyperandrogenic women with an exaggerated 17-hydroxyprogesterone response to short-term adrenal stimulation. Am J Obstet Gynecol. 172:(3):1995 Mar;914-918.
    • (1995) Am J Obstet Gynecol , vol.172 , Issue.3 , pp. 914-918
    • Azziz, R.1    Owerbach, D.2
  • 70
    • 0031405108 scopus 로고    scopus 로고
    • Hyperandrogenism and manifesting heterozygotes for 21-hydroxylase deficiency
    • Witchel S.F., Lee P.A., Suda-Hartman M., Hoffman E.P. Hyperandrogenism and manifesting heterozygotes for 21-hydroxylase deficiency. Biochem Mol Med. 62:(2):1997 Dec;151-158.
    • (1997) Biochem Mol Med , vol.62 , Issue.2 , pp. 151-158
    • Witchel, S.F.1    Lee, P.A.2    Suda-Hartman, M.3    Hoffman, E.P.4
  • 72
    • 0033673366 scopus 로고    scopus 로고
    • The role of heterozygosity for CYP21 in the polycystic ovary syndrome
    • Witchel S.F., Aston C.E. The role of heterozygosity for CYP21 in the polycystic ovary syndrome. J Pediatr Endocrinol Metab. 13:(Suppl 5):2000;1315-1317.
    • (2000) J Pediatr Endocrinol Metab , vol.13 , Issue.SUPPL. 5 , pp. 1315-1317
    • Witchel, S.F.1    Aston, C.E.2
  • 73
    • 0030832255 scopus 로고    scopus 로고
    • Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome
    • Gilling-Smith C., Story H., Rogers V., Franks S. Evidence for a primary abnormality of thecal cell steroidogenesis in the polycystic ovary syndrome. Clin Endocrinol (Oxf). 47:(1):1997 Jul;93-99.
    • (1997) Clin Endocrinol (Oxf) , vol.47 , Issue.1 , pp. 93-99
    • Gilling-Smith, C.1    Story, H.2    Rogers, V.3    Franks, S.4
  • 74
    • 0033724587 scopus 로고    scopus 로고
    • Androgen receptor gene CAG trinucleotide repeats in anovulatory infertility and polycystic ovaries
    • Mifsud A., Ramirez S., Yong E.L. Androgen receptor gene CAG trinucleotide repeats in anovulatory infertility and polycystic ovaries. J Clin Endocrinol Metab. 85:(9):2000 Sep;3484-3488.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.9 , pp. 3484-3488
    • Mifsud, A.1    Ramirez, S.2    Yong, E.L.3
  • 75
    • 0033587746 scopus 로고    scopus 로고
    • Thirty-seven candidate genes for polycystic ovary syndrome: Strongest evidence for linkage is with follistatin
    • Urbanek M., Legro R.S., Driscoll D.A., Azziz R., Ehrmann D.A., Norman R.J., et al. Thirty-seven candidate genes for polycystic ovary syndrome: strongest evidence for linkage is with follistatin. Proc Natl Acad Sci U S A. 96:(15):1999 Jul 20;8573-8578.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , Issue.15 JUL 20 , pp. 8573-8578
    • Urbanek, M.1    Legro, R.S.2    Driscoll, D.A.3    Azziz, R.4    Ehrmann, D.A.5    Norman, R.J.6
  • 76
    • 0036146428 scopus 로고    scopus 로고
    • The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome
    • Hickey T., Chandy A., Norman R.J. The androgen receptor CAG repeat polymorphism and X-chromosome inactivation in Australian Caucasian women with infertility related to polycystic ovary syndrome. J Clin Endocrinol Metab. 87:(1):2002 Jan;161-165.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.1 , pp. 161-165
    • Hickey, T.1    Chandy, A.2    Norman, R.J.3
  • 77
    • 0037622753 scopus 로고    scopus 로고
    • Androgen receptor gene CAG repeat polymorphism in the development of ovarian hyperandrogenism
    • Ibanez L., Ong K.K., Mongan N., Jaaskelainen J., Marcos M.V., Hughes I.A., et al. Androgen receptor gene CAG repeat polymorphism in the development of ovarian hyperandrogenism. J Clin Endocrinol Metab. 88:(7):2003 Jul;3333-3338.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.7 , pp. 3333-3338
    • Ibanez, L.1    Ong, K.K.2    Mongan, N.3    Jaaskelainen, J.4    Marcos, M.V.5    Hughes, I.A.6
  • 78
    • 0036221335 scopus 로고    scopus 로고
    • Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction
    • Hogeveen K.N., Cousin P., Pugeat M., Dewailly D., Soudan B., Hammond G.L. Human sex hormone-binding globulin variants associated with hyperandrogenism and ovarian dysfunction. J Clin Invest. 109:(7):2002 Apr;973-981.
    • (2002) J Clin Invest , vol.109 , Issue.7 , pp. 973-981
    • Hogeveen, K.N.1    Cousin, P.2    Pugeat, M.3    Dewailly, D.4    Soudan, B.5    Hammond, G.L.6
  • 79
    • 0024272188 scopus 로고
    • Detection of an alteration in the insulin-receptor gene in a patient with insulin resistance, acanthosis nigricans, and the polycystic ovary syndrome (type a insulin resistance)
    • Moller D.E., Flier J.S. Detection of an alteration in the insulin-receptor gene in a patient with insulin resistance, acanthosis nigricans, and the polycystic ovary syndrome (type A insulin resistance). N Engl J Med. 319:(23):1988 Dec 8;1526-1529.
    • (1988) N Engl J Med , vol.319 , Issue.23 , pp. 1526-1529
    • Moller, D.E.1    Flier, J.S.2
  • 81
    • 0036902524 scopus 로고    scopus 로고
    • A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome
    • Siegel S., Futterweit W., Davies T.F., Concepcion E.S., Greenberg D.A., Villanueva R., et al. A C/T single nucleotide polymorphism at the tyrosine kinase domain of the insulin receptor gene is associated with polycystic ovary syndrome. Fertil Steril. 78:(6):2002 Dec;1240-1243.
    • (2002) Fertil Steril , vol.78 , Issue.6 , pp. 1240-1243
    • Siegel, S.1    Futterweit, W.2    Davies, T.F.3    Concepcion, E.S.4    Greenberg, D.A.5    Villanueva, R.6
  • 82
    • 0035142308 scopus 로고    scopus 로고
    • Evidence for association of polycystic ovary syndrome in caucasian women with a marker at the insulin receptor gene locus
    • Tucci S., Futterweit W., Concepcion E.S., Greenberg D.A., Villanueva R., Davies T.F., et al. Evidence for association of polycystic ovary syndrome in caucasian women with a marker at the insulin receptor gene locus. J Clin Endocrinol Metab. 86:(1):2001 Jan;446-449.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.1 , pp. 446-449
    • Tucci, S.1    Futterweit, W.2    Concepcion, E.S.3    Greenberg, D.A.4    Villanueva, R.5    Davies, T.F.6
  • 83
    • 0030895556 scopus 로고    scopus 로고
    • Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome
    • Waterworth D.M., Bennett S.T., Gharani N., McCarthy M.I., Hague S., Batty S., et al. Linkage and association of insulin gene VNTR regulatory polymorphism with polycystic ovary syndrome. Lancet. 349:(9057):1997 Apr 5;986-990.
    • (1997) Lancet , vol.349 , Issue.9057 , pp. 986-990
    • Waterworth, D.M.1    Bennett, S.T.2    Gharani, N.3    McCarthy, M.I.4    Hague, S.5    Batty, S.6
  • 84
    • 0035217582 scopus 로고    scopus 로고
    • Insulin gene variable number of tandem repeat genotype and the low birth weight, precocious pubarche, and hyperinsulinism sequence
    • Ibanez L., Ong K., Potau N., Marcos M.V., de Zegher F., Dunger D. Insulin gene variable number of tandem repeat genotype and the low birth weight, precocious pubarche, and hyperinsulinism sequence. J Clin Endocrinol Metab. 86:(12):2001 Dec;5788-5793.
    • (2001) J Clin Endocrinol Metab , vol.86 , Issue.12 , pp. 5788-5793
    • Ibanez, L.1    Ong, K.2    Potau, N.3    Marcos, M.V.4    De Zegher, F.5    Dunger, D.6
  • 85
    • 0035125526 scopus 로고    scopus 로고
    • IRS proteins and beta-cell function
    • Burks D.J., White M.F. IRS proteins and beta-cell function. Diabetes. 50:(Suppl 1):2001 Feb;S140-S145.
    • (2001) Diabetes , vol.50 , Issue.SUPPL. 1
    • Burks, D.J.1    White, M.F.2
  • 86
    • 0035461406 scopus 로고    scopus 로고
    • Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome
    • Mkadem S.A., Lautier C., Macari F., Molinari N., Lefebvre P., Renard E., et al. Role of allelic variants Gly972Arg of IRS-1 and Gly1057Asp of IRS-2 in moderate-to-severe insulin resistance of women with polycystic ovary syndrome. Diabetes. 50:(9):2001 Sep;2164-2168.
    • (2001) Diabetes , vol.50 , Issue.9 , pp. 2164-2168
    • Mkadem, S.A.1    Lautier, C.2    MacAri, F.3    Molinari, N.4    Lefebvre, P.5    Renard, E.6
  • 87
    • 0034891885 scopus 로고    scopus 로고
    • Defects in insulin receptor signaling in vivo in the polycystic ovary syndrome (PCOS)
    • Dunaif A., Wu X., Lee A., Diamanti-Kandarakis E. Defects in insulin receptor signaling in vivo in the polycystic ovary syndrome (PCOS). Am J Physiol Endocrinol Metab. 281:(2):2001 Aug;E392-E399.
    • (2001) Am J Physiol Endocrinol Metab , vol.281 , Issue.2
    • Dunaif, A.1    Wu, X.2    Lee, A.3    Diamanti-Kandarakis, E.4
  • 88
    • 0036738335 scopus 로고    scopus 로고
    • Decreased insulin receptor (IR) autophosphorylation in fibroblasts from patients with PCOS: Effects of serine kinase inhibitors and IR activators
    • Li M., Youngren J.F., Dunaif A., Goldfine I.D., Maddux B.A., Zhang B.B., et al. Decreased insulin receptor (IR) autophosphorylation in fibroblasts from patients with PCOS: effects of serine kinase inhibitors and IR activators. J Clin Endocrinol Metab. 87:(9):2002 Sep;4088-4093.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.9 , pp. 4088-4093
    • Li, M.1    Youngren, J.F.2    Dunaif, A.3    Goldfine, I.D.4    Maddux, B.A.5    Zhang, B.B.6
  • 89
    • 0036283852 scopus 로고    scopus 로고
    • Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome
    • Ehrmann D.A., Schwarz P.E., Hara M., Tang X., Horikawa Y., Imperial J., et al. Relationship of calpain-10 genotype to phenotypic features of polycystic ovary syndrome. J Clin Endocrinol Metab. 87:(4):2002 Apr;1669-1673.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.4 , pp. 1669-1673
    • Ehrmann, D.A.1    Schwarz, P.E.2    Hara, M.3    Tang, X.4    Horikawa, Y.5    Imperial, J.6
  • 91
    • 0037219110 scopus 로고    scopus 로고
    • Variation in resistin gene promoter not associated with polycystic ovary syndrome
    • Urbanek M., Du Y., Silander K., Collins F.S., Steppan C.M., Strauss J.F. 3rd, et al. Variation in resistin gene promoter not associated with polycystic ovary syndrome. Diabetes. 52:(1):2003 Jan;214-217.
    • (2003) Diabetes , vol.52 , Issue.1 , pp. 214-217
    • Urbanek, M.1    Du, Y.2    Silander, K.3    Collins, F.S.4    Steppan, C.M.5    Strauss III, J.F.6
  • 92
    • 0032586938 scopus 로고    scopus 로고
    • Role of the mutations Trp8 => Arg and Ile15 => Thr of the human luteinizing hormone beta-subunit in women with polycystic ovary syndrome
    • Elter K., Erel C.T., Cine N., Ozbek U., Hacihanefioglu B., Ertungealp E. Role of the mutations Trp8 => Arg and Ile15 => Thr of the human luteinizing hormone beta-subunit in women with polycystic ovary syndrome. Fertil Steril. 71:(3):1999 Mar;425-430.
    • (1999) Fertil Steril , vol.71 , Issue.3 , pp. 425-430
    • Elter, K.1    Erel, C.T.2    Cine, N.3    Ozbek, U.4    Hacihanefioglu, B.5    Ertungealp, E.6
  • 93
    • 0033361906 scopus 로고    scopus 로고
    • Naturally occurring mutations of the luteinizing-hormone receptor: Lessons learned about reproductive physiology and G protein-coupled receptors
    • Review
    • Latronico A.C., Segaloff D.L. Naturally occurring mutations of the luteinizing-hormone receptor: lessons learned about reproductive physiology and G protein-coupled receptors. Am J Hum Genet. 65:(4):1999 Oct;949-958. Review.
    • (1999) Am J Hum Genet , vol.65 , Issue.4 , pp. 949-958
    • Latronico, A.C.1    Segaloff, D.L.2
  • 94
    • 0033637414 scopus 로고    scopus 로고
    • Association of AccI polymorphism in the follicle-stimulating hormone beta gene with polycystic ovary syndrome
    • Tong Y., Liao W.X., Roy A.C., Ng S.C. Association of AccI polymorphism in the follicle-stimulating hormone beta gene with polycystic ovary syndrome. Fertil Steril. 74:(6):2000 Dec;1233-1236.
    • (2000) Fertil Steril , vol.74 , Issue.6 , pp. 1233-1236
    • Tong, Y.1    Liao, W.X.2    Roy, A.C.3    Ng, S.C.4
  • 95
    • 0032800694 scopus 로고    scopus 로고
    • Mutation screening and isoform prevalence of the follicle stimulating hormone receptor gene in women with premature ovarian failure, resistant ovary syndrome and polycystic ovary syndrome
    • Conway G.S., Conway E., Walker C., Hoppner W., Gromoll J., Simoni M. Mutation screening and isoform prevalence of the follicle stimulating hormone receptor gene in women with premature ovarian failure, resistant ovary syndrome and polycystic ovary syndrome. Clin Endocrinol (Oxf). 51:(1):1999 Jul;97-99.
    • (1999) Clin Endocrinol (Oxf) , vol.51 , Issue.1 , pp. 97-99
    • Conway, G.S.1    Conway, E.2    Walker, C.3    Hoppner, W.4    Gromoll, J.5    Simoni, M.6
  • 97
    • 0028988282 scopus 로고
    • A dopamine D3 receptor genotype is associated with hyperandrogenic chronic anovulation and resistant to ovulation induction with clomiphene citrate in female Hispanics
    • Legro R.S., Muhleman D.R., Comings D.E., Lobo R.A., Kovacs B.W. A dopamine D3 receptor genotype is associated with hyperandrogenic chronic anovulation and resistant to ovulation induction with clomiphene citrate in female Hispanics. Fertil Steril. 63:(4):1995 Apr;779-784.
    • (1995) Fertil Steril , vol.63 , Issue.4 , pp. 779-784
    • Legro, R.S.1    Muhleman, D.R.2    Comings, D.E.3    Lobo, R.A.4    Kovacs, B.W.5
  • 98
    • 0032586940 scopus 로고    scopus 로고
    • Dopamine D3 receptor polymorphism is not associated with the polycystic ovary syndrome
    • Kahsar-Miller M., Boots L.R., Azziz R. Dopamine D3 receptor polymorphism is not associated with the polycystic ovary syndrome. Fertil Steril. 71:(3): 1999 Mar;436-438.
    • (1999) Fertil Steril , vol.71 , Issue.3 , pp. 436-438
    • Kahsar-Miller, M.1    Boots, L.R.2    Azziz, R.3
  • 99
    • 0020681348 scopus 로고
    • HLA genotyping in family members and patients with familial polycystic ovarian disease
    • Mandel F.P., Chang R.J., Dupont B., Pollack M.S., Levine L.S., New M.I., et al. HLA genotyping in family members and patients with familial polycystic ovarian disease. J Clin Endocrinol Metab. 56:(4):1983 Apr;862-864.
    • (1983) J Clin Endocrinol Metab , vol.56 , Issue.4 , pp. 862-864
    • Mandel, F.P.1    Chang, R.J.2    Dupont, B.3    Pollack, M.S.4    Levine, L.S.5    New, M.I.6
  • 100
    • 0025287725 scopus 로고
    • HLA associations in patients with polycystic ovaries and in patients with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency
    • Hague W.M., Adams J., Algar V., Drummond V., Schwarz G., Bottazzo G.F., et al. HLA associations in patients with polycystic ovaries and in patients with congenital adrenal hyperplasia caused by 21-hydroxylase deficiency. Clin Endocrinol (Oxf). 32:(4):1990 Apr;407-415.
    • (1990) Clin Endocrinol (Oxf) , vol.32 , Issue.4 , pp. 407-415
    • Hague, W.M.1    Adams, J.2    Algar, V.3    Drummond, V.4    Schwarz, G.5    Bottazzo, G.F.6
  • 101
    • 0026676212 scopus 로고
    • Increased risk for polycystic ovary syndrome associated with human leukocyte antigen DQA1*0501
    • Ober C., Weil S., Steck T., Billstrand C., Levrant S., Barnes R. Increased risk for polycystic ovary syndrome associated with human leukocyte antigen DQA1*0501. Am J Obstet Gynecol. 167:(6):1992 Dec;1803-1806.
    • (1992) Am J Obstet Gynecol , vol.167 , Issue.6 , pp. 1803-1806
    • Ober, C.1    Weil, S.2    Steck, T.3    Billstrand, C.4    Levrant, S.5    Barnes, R.6
  • 102
    • 0033694297 scopus 로고    scopus 로고
    • Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in non obese, adolescent girls: Effect of flutamide
    • Ibanez L., Potau N., Marcos M.V., de Zegher F. Treatment of hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism in non obese, adolescent girls: effect of flutamide. J Clin Endocrinol Metab. 85:(9):2000 Sep;3251-3255.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.9 , pp. 3251-3255
    • Ibanez, L.1    Potau, N.2    Marcos, M.V.3    De Zegher, F.4
  • 103
    • 0037203511 scopus 로고    scopus 로고
    • Evidence that chlormadinone acetate exhibits antiandrogenic activity in androgen-dependent cell line
    • Terouanne B., Paris F., Servant N., Georget V., Sultan C. Evidence that chlormadinone acetate exhibits antiandrogenic activity in androgen-dependent cell line. Mol Cell Endocrinol. 198:(1-2):2002 Dec 30;143-147.
    • (2002) Mol Cell Endocrinol , vol.198 , Issue.12 , pp. 143-147
    • Terouanne, B.1    Paris, F.2    Servant, N.3    Georget, V.4    Sultan, C.5
  • 104
    • 0034880066 scopus 로고    scopus 로고
    • Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS)
    • Glueck C.J., Wang P., Fontaine R., Tracy T., Sieve-Smith L. Metformin to restore normal menses in oligo-amenorrheic teenage girls with polycystic ovary syndrome (PCOS). J Adolesc Health. 29:(3):2001 Sep;160-169.
    • (2001) J Adolesc Health , vol.29 , Issue.3 , pp. 160-169
    • Glueck, C.J.1    Wang, P.2    Fontaine, R.3    Tracy, T.4    Sieve-Smith, L.5
  • 105
    • 0033756465 scopus 로고    scopus 로고
    • Sensitization to insulin in adolescent girls to normalize hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism after precocious pubarche
    • Ibanez L., Valls C., Potau N., Marcos M.V., de Zegher F. Sensitization to insulin in adolescent girls to normalize hirsutism, hyperandrogenism, oligomenorrhea, dyslipidemia, and hyperinsulinism after precocious pubarche. J Clin Endocrinol Metab. 85:(10):2000 Oct;3526-3530.
    • (2000) J Clin Endocrinol Metab , vol.85 , Issue.10 , pp. 3526-3530
    • Ibanez, L.1    Valls, C.2    Potau, N.3    Marcos, M.V.4    De Zegher, F.5
  • 106
    • 0345505642 scopus 로고    scopus 로고
    • Metformin has direct effects on human ovarian steroidogenesis
    • Mansfield R., Galea R., Brincat M., Hole D., Mason H. Metformin has direct effects on human ovarian steroidogenesis. Fertil Steril. 79:(4):2003 Apr;956-962.
    • (2003) Fertil Steril , vol.79 , Issue.4 , pp. 956-962
    • Mansfield, R.1    Galea, R.2    Brincat, M.3    Hole, D.4    Mason, H.5
  • 107
    • 0036283875 scopus 로고    scopus 로고
    • Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: Amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia/insulin resistance
    • Arslanian S.A., Lewy V., Danadian K., Saad R. Metformin therapy in obese adolescents with polycystic ovary syndrome and impaired glucose tolerance: amelioration of exaggerated adrenal response to adrenocorticotropin with reduction of insulinemia/insulin resistance. J Clin Endocrinol Metab. 87:(4):2002 Apr;1555-1559.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.4 , pp. 1555-1559
    • Arslanian, S.A.1    Lewy, V.2    Danadian, K.3    Saad, R.4
  • 108
    • 0038644550 scopus 로고    scopus 로고
    • Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism
    • Ibanez L., Ong K., Ferrer A., Amin R., Dunger D., de Zegher F. Low-dose flutamide-metformin therapy reverses insulin resistance and reduces fat mass in nonobese adolescents with ovarian hyperandrogenism. J Clin Endocrinol Metab. 88:(6):2003 Jun;2600-2606.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.6 , pp. 2600-2606
    • Ibanez, L.1    Ong, K.2    Ferrer, A.3    Amin, R.4    Dunger, D.5    De Zegher, F.6
  • 109
    • 0036078815 scopus 로고    scopus 로고
    • Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation
    • Ibanez L., Valls C., Ferrer A., Ong K., Dunger D.B., De Zegher F. Additive effects of insulin-sensitizing and anti-androgen treatment in young, nonobese women with hyperinsulinism, hyperandrogenism, dyslipidemia, and anovulation. J Clin Endocrinol Metab. 87:(6):2002 Jun;2870-2874.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.6 , pp. 2870-2874
    • Ibanez, L.1    Valls, C.2    Ferrer, A.3    Ong, K.4    Dunger, D.B.5    De Zegher, F.6
  • 110
    • 0037247208 scopus 로고    scopus 로고
    • Low-dose combination of flutamide, metformin and an oral contraceptive for non-obese, young women with polycystic ovary syndrome
    • Ibanez L., de Zegher F. Low-dose combination of flutamide, metformin and an oral contraceptive for non-obese, young women with polycystic ovary syndrome. Hum Reprod. 18:(1):2003 Jan;57-60.
    • (2003) Hum Reprod , vol.18 , Issue.1 , pp. 57-60
    • Ibanez, L.1    De Zegher, F.2
  • 111
    • 0037883233 scopus 로고    scopus 로고
    • Metformin Use in Adolescent with PCOS-An Invited Editorial from the Pediatric Endocrinology Perspective
    • Jamieson E.M., Dean H. Metformin Use in Adolescent with PCOS-An Invited Editorial from the Pediatric Endocrinology Perspective. J Pediatr Adolesc Gynecol. 16:(2):2003 Apr;109-111.
    • (2003) J Pediatr Adolesc Gynecol , vol.16 , Issue.2 , pp. 109-111
    • Jamieson, E.M.1    Dean, H.2
  • 112
    • 0037326410 scopus 로고    scopus 로고
    • Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome
    • Paradisi G., Steinberg H.O., Shepard M.K., Hook G., Baron A.D. Troglitazone therapy improves endothelial function to near normal levels in women with polycystic ovary syndrome. J Clin Endocrinol Metab. 88:(2):2003 Feb;576-580.
    • (2003) J Clin Endocrinol Metab , vol.88 , Issue.2 , pp. 576-580
    • Paradisi, G.1    Steinberg, H.O.2    Shepard, M.K.3    Hook, G.4    Baron, A.D.5
  • 113
    • 0036962952 scopus 로고    scopus 로고
    • Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro
    • Veldhuis J.D., Zhang G., Garmey J.C. Troglitazone, an insulin-sensitizing thiazolidinedione, represses combined stimulation by LH and insulin of de novo androgen biosynthesis by thecal cells in vitro. J Clin Endocrinol Metab. 87:(3):2002 Mar;1129-1133.
    • (2002) J Clin Endocrinol Metab , vol.87 , Issue.3 , pp. 1129-1133
    • Veldhuis, J.D.1    Zhang, G.2    Garmey, J.C.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.