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Volumn 29, Issue 3, 2002, Pages 274-285

Hemochromatosis protein (HFE) and tumor necrosis factor receptor 2 (TNFR2) influence tissue iron levels: Elements of a common gut pathway?

Author keywords

[No Author keywords available]

Indexed keywords

HFE PROTEIN, MOUSE; HLA ANTIGEN CLASS 1; IRON; LEUKOCYTE ANTIGEN; MEMBRANE PROTEIN; TUMOR NECROSIS FACTOR RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR 2;

EID: 0642318351     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.2002.0565     Document Type: Article
Times cited : (14)

References (56)
  • 1
    • 0033575729 scopus 로고    scopus 로고
    • Metal ion transporters and homeostasis
    • N. Nelson Metal ion transporters and homeostasis EMBO J. 18 1999 4361 4371
    • (1999) EMBO J. , vol.18 , pp. 4361-4371
    • Nelson, N.1
  • 3
    • 0033599057 scopus 로고    scopus 로고
    • Disorders of iron metabolism
    • N.C. Andrews Disorders of iron metabolism N. Engl. J. Med. 341 1999 1986 1995
    • (1999) N. Engl. J. Med. , vol.341 , pp. 1986-1995
    • Andrews, N.C.1
  • 4
    • 0034575478 scopus 로고    scopus 로고
    • Iron metabolism: Iron deficiency and iron overload
    • N.C. Andrews Iron metabolism: Iron deficiency and iron overload Annu. Rev. Genomics Hum. Genet. 1 2000 75 98
    • (2000) Annu. Rev. Genomics Hum. Genet. , vol.1 , pp. 75-98
    • Andrews, N.C.1
  • 5
    • 0035474950 scopus 로고    scopus 로고
    • Recent advances in disorders of iron metabolism: Mutations, mechanisms and modifiers
    • C.N. Roy N.C. Andrews Recent advances in disorders of iron metabolism: Mutations, mechanisms and modifiers Hum. Mol. Genet. 10 2001 2181 2186
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2181-2186
    • Roy, C.N.1    Andrews, N.C.2
  • 6
    • 0032716978 scopus 로고    scopus 로고
    • The hereditary hemochromatosis gene (HFE): A MHC class I-like gene that functions in the regulation of iron homeostasis
    • J.N. Feder The hereditary hemochromatosis gene (HFE): A MHC class I-like gene that functions in the regulation of iron homeostasis Immunol. Res. 20 1999 175 185
    • (1999) Immunol. Res. , vol.20 , pp. 175-185
    • Feder, J.N.1
  • 7
    • 0033759823 scopus 로고    scopus 로고
    • Haemochromatosis: Novel gene discovery and the molecular pathophysiology of iron metabolism
    • W. Griffiths T. Cox Haemochromatosis: Novel gene discovery and the molecular pathophysiology of iron metabolism Hum. Mol. Genet. 9 2000 2377 2382
    • (2000) Hum. Mol. Genet. , vol.9 , pp. 2377-2382
    • Griffiths, W.1    Cox, T.2
  • 8
    • 0033922443 scopus 로고    scopus 로고
    • The structure and function of HFE
    • H. Drakesmith A. Townsend The structure and function of HFE Bioessays 22 2000 595 598
    • (2000) Bioessays , vol.22 , pp. 595-598
    • Drakesmith, H.1    Townsend, A.2
  • 9
    • 0033634877 scopus 로고    scopus 로고
    • HFE—A novel nonclassical class I molecule that is involved in iron metabolism
    • R. Ehrlich F.A. Lemonnier HFE—A novel nonclassical class I molecule that is involved in iron metabolism Immunity 13 2000 585 588
    • (2000) Immunity , vol.13 , pp. 585-588
    • Ehrlich, R.1    Lemonnier, F.A.2
  • 10
  • 11
    • 0029051815 scopus 로고
    • Linkage of cell-mediated immunity to iron metabolism
    • G. Weiss H. Wachter D. Fuchs Linkage of cell-mediated immunity to iron metabolism Immunol. Today 16 1995 495 500
    • (1995) Immunol. Today , vol.16 , pp. 495-500
    • Weiss, G.1    Wachter, H.2    Fuchs, D.3
  • 12
  • 13
    • 0031982370 scopus 로고    scopus 로고
    • The immunological system in hemochromatosis
    • M. de Sousa G. Porto The immunological system in hemochromatosis J. Hepatol. 28 1998 1 7
    • (1998) J. Hepatol. , vol.28 , pp. 1-7
    • de Sousa, M.1    Porto, G.2
  • 15
    • 0028264088 scopus 로고
    • Haemochromatosis as a window into the study of the immunological system: A novel correlation between CD8+ lymphocytes and iron overload
    • G. Porto R. Reimao C. Goncalves C. Vicente B. Justica M. de Sousa Haemochromatosis as a window into the study of the immunological system: A novel correlation between CD8+ lymphocytes and iron overload Eur. J. Haematol. 52 1994 283 290
    • (1994) Eur. J. Haematol. , vol.52 , pp. 283-290
    • Porto, G.1    Reimao, R.2    Goncalves, C.3    Vicente, C.4    Justica, B.5    de Sousa, M.6
  • 16
    • 9344224529 scopus 로고    scopus 로고
    • A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
    • J.N. Feder A. Gnirke W. Thomas A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis Nature Genet. 13 1996 399 408
    • (1996) Nature Genet. , vol.13 , pp. 399-408
    • Feder, J.N.1    Gnirke, A.2    Thomas, W.3
  • 17
    • 13144282684 scopus 로고    scopus 로고
    • The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
    • J.N. Feder D.M. Penny A. Irrinki The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding Proc. Natl. Acad. Sci. USA 95 1998 1472 1477
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 1472-1477
    • Feder, J.N.1    Penny, D.M.2    Irrinki, A.3
  • 18
    • 0033585129 scopus 로고    scopus 로고
    • The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor
    • J.A. Lebron A.P. West Jr. P.J. Bjorkman The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor J. Mol. Biol. 294 1999 239 245
    • (1999) J. Mol. Biol. , vol.294 , pp. 239-245
    • Lebron, J.A.1    West, A.P.2    Bjorkman, P.J.3
  • 19
    • 0030639030 scopus 로고    scopus 로고
    • Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13
    • G. Weiss C. Bogdan M.W. Hentze Pathways for the regulation of macrophage iron metabolism by the anti-inflammatory cytokines IL-4 and IL-13 J. Immunol. 158 1997 420 425
    • (1997) J. Immunol. , vol.158 , pp. 420-425
    • Weiss, G.1    Bogdan, C.2    Hentze, M.W.3
  • 20
    • 0028962892 scopus 로고
    • Identification and characterization of a second mouse Nramp gene
    • S. Gruenheid M. Cellier S. Vidal P. Gros Identification and characterization of a second mouse Nramp gene Genomics 25 1995 514 525
    • (1995) Genomics , vol.25 , pp. 514-525
    • Gruenheid, S.1    Cellier, M.2    Vidal, S.3    Gros, P.4
  • 21
    • 0027262167 scopus 로고
    • Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg
    • S.M. Vidal D. Malo K. Vogan E. Skamene P. Gros Natural resistance to infection with intracellular parasites: Isolation of a candidate for Bcg Cell 73 1993 469 485
    • (1993) Cell , vol.73 , pp. 469-485
    • Vidal, S.M.1    Malo, D.2    Vogan, K.3    Skamene, E.4    Gros, P.5
  • 22
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • G. Nicolas M. Bennoun I. Devaux Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice Proc. Natl. Acad. Sci. USA 98 2001 8780 8785
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 8780-8785
    • Nicolas, G.1    Bennoun, M.2    Devaux, I.3
  • 23
    • 0030964447 scopus 로고    scopus 로고
    • Local hormone networks and intestinal T cell homeostasis
    • J. Wang M. Whetsell J.R. Klein Local hormone networks and intestinal T cell homeostasis Science 275 1997 1937 1939
    • (1997) Science , vol.275 , pp. 1937-1939
    • Wang, J.1    Whetsell, M.2    Klein, J.R.3
  • 24
    • 0032947432 scopus 로고    scopus 로고
    • Gamma delta intraepithelial lymphocytes drive tumor necrosis factor-alpha responsiveness to intestinal iron challenge: Relevance to hemochromatosis
    • A.E. Ten Elshof G.M. Brittenham K.A. Chorney M.J. Page G. Gerhard E.E. Cable M.J. Chorney Gamma delta intraepithelial lymphocytes drive tumor necrosis factor-alpha responsiveness to intestinal iron challenge: Relevance to hemochromatosis Immunol. Rev. 167 1999 223 232
    • (1999) Immunol. Rev. , vol.167 , pp. 223-232
    • Ten Elshof, A.E.1    Brittenham, G.M.2    Chorney, K.A.3    Page, M.J.4    Gerhard, G.5    Cable, E.E.6    Chorney, M.J.7
  • 25
    • 0026606666 scopus 로고
    • Decreased concentrations of tumor necrosis factor-alpha in supernatants of monocytes from homozygotes for hereditary hemochromatosis
    • V.R. Gordeuk S. Ballou G. Lozanski G.M. Brittenham Decreased concentrations of tumor necrosis factor-alpha in supernatants of monocytes from homozygotes for hereditary hemochromatosis Blood 79 1992 1855 1860
    • (1992) Blood , vol.79 , pp. 1855-1860
    • Gordeuk, V.R.1    Ballou, S.2    Lozanski, G.3    Brittenham, G.M.4
  • 26
    • 0035877982 scopus 로고    scopus 로고
    • Tumor necrosis factor alpha promoter polymorphisms influence the phenotypic expression of hereditary hemochromatosis
    • S. Fargion L. Valenti P. Dongiovanni Tumor necrosis factor alpha promoter polymorphisms influence the phenotypic expression of hereditary hemochromatosis Blood 97 2001 3707 3712
    • (2001) Blood , vol.97 , pp. 3707-3712
    • Fargion, S.1    Valenti, L.2    Dongiovanni, P.3
  • 27
    • 0034572933 scopus 로고    scopus 로고
    • Iron homeostasis: Insights from genetics and animal models
    • N.C. Andrews Iron homeostasis: Insights from genetics and animal models Nature Rev. Genet. 1 2000 208 217
    • (2000) Nature Rev. Genet. , vol.1 , pp. 208-217
    • Andrews, N.C.1
  • 28
    • 85120224307 scopus 로고    scopus 로고
    • Torrance, J. D, and, Bothwell, T. H. 1980, Tissue iron stores, In , Methods in Hematology, (, Cook, J. D, Ed.), Vol, 1, pp, 104, Churchill Livingstone, New York.
  • 29
    • 85120238683 scopus 로고    scopus 로고
    • Luna, L. G. (Ed.), 1968, Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology, McGraw-Hill, New York.
  • 31
    • 85120189674 scopus 로고    scopus 로고
    • Lefrancois, L.1994Isolation of mouse small intestinal intraepithelial lymphocytes. In Current Protocols in Immunology (Cologan, J. E., Kruisbeek, A. M., Margulies, D. H., Shevach, E. M., Strober, W., Eds.), Vol. 1, pp. 3.19.1–3.19.7. Wiley, New York.
  • 32
    • 0033711184 scopus 로고    scopus 로고
    • The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137
    • P.A. Lyons W.W. Hancock P. Denny The NOD Idd9 genetic interval influences the pathogenicity of insulitis and contains molecular variants of Cd30, Tnfr2, and Cd137 Immunity 13 2000 107 115
    • (2000) Immunity , vol.13 , pp. 107-115
    • Lyons, P.A.1    Hancock, W.W.2    Denny, P.3
  • 33
    • 0027435650 scopus 로고
    • Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption
    • P. Nielsen S. Heinelt J. Dullmann Chronic feeding of carbonyl-iron and TMH-ferrocene in rats. Comparison of two iron-overload models with different iron absorption Comp. Biochem. Physiol. C 106 1993 429 436
    • (1993) Comp. Biochem. Physiol. C , vol.106 , pp. 429-436
    • Nielsen, P.1    Heinelt, S.2    Dullmann, J.3
  • 34
    • 0028533759 scopus 로고
    • Allelic variation of the type 2 tumor necrosis factor receptor gene
    • E.E. Powell L.S. Wicker L.B. Peterson J.A. Todd Allelic variation of the type 2 tumor necrosis factor receptor gene Mamm. Genome 5 1994 726 727
    • (1994) Mamm. Genome , vol.5 , pp. 726-727
    • Powell, E.E.1    Wicker, L.S.2    Peterson, L.B.3    Todd, J.A.4
  • 35
    • 0031985413 scopus 로고    scopus 로고
    • TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation
    • J.J. Peschon D.S. Torrance K.L. Stocking TNF receptor-deficient mice reveal divergent roles for p55 and p75 in several models of inflammation J. Immunol. 160 1998 943 952
    • (1998) J. Immunol. , vol.160 , pp. 943-952
    • Peschon, J.J.1    Torrance, D.S.2    Stocking, K.L.3
  • 36
    • 0028981059 scopus 로고
    • Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha
    • E.L. Kwak D.A. Larochelle C. Beaumont S.V. Torti F.M. Torti Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha J. Biol. Chem. 270 1995 15285 15293
    • (1995) J. Biol. Chem. , vol.270 , pp. 15285-15293
    • Kwak, E.L.1    Larochelle, D.A.2    Beaumont, C.3    Torti, S.V.4    Torti, F.M.5
  • 37
    • 0026760450 scopus 로고
    • Progress in understanding the pathogenesis of the anemia of chronic disease
    • R.T. Means Jr. S.B. Krantz Progress in understanding the pathogenesis of the anemia of chronic disease Blood 80 1992 1639 1647
    • (1992) Blood , vol.80 , pp. 1639-1647
    • Means, R.T.1    Krantz, S.B.2
  • 38
    • 0031857792 scopus 로고    scopus 로고
    • Regulation of iron metabolism in the acute-phase response: Interferon gamma and tumour necrosis factor alpha induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients
    • R.A. Feelders G. Vreugdenhil A.M. Eggermont P.A. Kuiper-Kramer H.G. van Eijk A.J. Swaak Regulation of iron metabolism in the acute-phase response: Interferon gamma and tumour necrosis factor alpha induce hypoferraemia, ferritin production and a decrease in circulating transferrin receptors in cancer patients Eur. J. Clin. Invest. 28 1998 520 527
    • (1998) Eur. J. Clin. Invest. , vol.28 , pp. 520-527
    • Feelders, R.A.1    Vreugdenhil, G.2    Eggermont, A.M.3    Kuiper-Kramer, P.A.4    van Eijk, H.G.5    Swaak, A.J.6
  • 40
    • 0031454793 scopus 로고    scopus 로고
    • Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron
    • T.N. Tran S.K. Eubanks K.J. Schaffer C.Y. Zhou M.C. Linder Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron Blood 90 1997 4979 4986
    • (1997) Blood , vol.90 , pp. 4979-4986
    • Tran, T.N.1    Eubanks, S.K.2    Schaffer, K.J.3    Zhou, C.Y.4    Linder, M.C.5
  • 43
    • 0001376313 scopus 로고    scopus 로고
    • HFE gene knockout produces mouse model of hereditary hemochromatosis
    • X.Y. Zhou S. Tomatsu R.E. Fleming HFE gene knockout produces mouse model of hereditary hemochromatosis Proc. Natl. Acad. Sci. USA 95 1998 2492 2497
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 2492-2497
    • Zhou, X.Y.1    Tomatsu, S.2    Fleming, R.E.3
  • 44
    • 0034254794 scopus 로고    scopus 로고
    • Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis
    • G. Montosi P. Paglia C. Garuti C.A. Guzman J.M. Bastin M.P. Colombo A. Pietrangelo Wild-type HFE protein normalizes transferrin iron accumulation in macrophages from subjects with hereditary hemochromatosis Blood 96 2000 1125 1129
    • (2000) Blood , vol.96 , pp. 1125-1129
    • Montosi, G.1    Paglia, P.2    Garuti, C.3    Guzman, C.A.4    Bastin, J.M.5    Colombo, M.P.6    Pietrangelo, A.7
  • 45
    • 0037117603 scopus 로고    scopus 로고
    • Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse
    • D. Trinder J.K. Olynyk W.S. Sly E.H. Morgan Iron uptake from plasma transferrin by the duodenum is impaired in the Hfe knockout mouse Proc. Natl. Acad. Sci. USA 99 2002 5622 5626
    • (2002) Proc. Natl. Acad. Sci. USA , vol.99 , pp. 5622-5626
    • Trinder, D.1    Olynyk, J.K.2    Sly, W.S.3    Morgan, E.H.4
  • 46
    • 0033927268 scopus 로고    scopus 로고
    • The major histocompatibility complex-encoded HFE in iron homeostasis and immune function
    • L. Salter-Cid P.A. Peterson Y. Yang The major histocompatibility complex-encoded HFE in iron homeostasis and immune function Immunol. Res. 22 2000 43 59
    • (2000) Immunol. Res. , vol.22 , pp. 43-59
    • Salter-Cid, L.1    Peterson, P.A.2    Yang, Y.3
  • 47
    • 0032427653 scopus 로고    scopus 로고
    • Kupffer cell staining by an HFE-specific monoclonal antibody: Implications for hereditary haemochromatosis
    • J.M. Bastin M. Jones C.A. O'Callaghan L. Schimanski D.Y. Mason A.R. Townsend Kupffer cell staining by an HFE-specific monoclonal antibody: Implications for hereditary haemochromatosis Br. J. Haematol. 103 1998 931 941
    • (1998) Br. J. Haematol. , vol.103 , pp. 931-941
    • Bastin, J.M.1    Jones, M.2    O'Callaghan, C.A.3    Schimanski, L.4    Mason, D.Y.5    Townsend, A.R.6
  • 48
    • 0032721955 scopus 로고    scopus 로고
    • Associations between cellular immune effector function, iron metabolism, and disease activity in patients with chronic hepatitis C virus infection
    • G. Weiss F. Umlauft M. Urbanek M. Herold M. Lovevsky F. Offner V.R. Gordeuk Associations between cellular immune effector function, iron metabolism, and disease activity in patients with chronic hepatitis C virus infection J. Infect. Dis. 180 1999 1452 1458
    • (1999) J. Infect. Dis. , vol.180 , pp. 1452-1458
    • Weiss, G.1    Umlauft, F.2    Urbanek, M.3    Herold, M.4    Lovevsky, M.5    Offner, F.6    Gordeuk, V.R.7
  • 49
    • 0033625501 scopus 로고    scopus 로고
    • The temporal importance of TNFalpha expression in the development of diabetes
    • E.A. Green R.A. Flavell The temporal importance of TNFalpha expression in the development of diabetes Immunity 12 2000 459 469
    • (2000) Immunity , vol.12 , pp. 459-469
    • Green, E.A.1    Flavell, R.A.2
  • 50
    • 0034846013 scopus 로고    scopus 로고
    • Hemochromatosis at the intersection of classical medicine and molecular biology
    • P. Brissot Hemochromatosis at the intersection of classical medicine and molecular biology CR Acad Sci III 324 2001 795 804
    • (2001) CR Acad Sci III , vol.324 , pp. 795-804
    • Brissot, P.1
  • 51
    • 0035892888 scopus 로고    scopus 로고
    • TNF type 2 receptor (p75) lowers the threshold of T cell activation
    • E.Y. Kim H.S. Teh TNF type 2 receptor (p75) lowers the threshold of T cell activation J. Immunol. 167 2001 6812 6820
    • (2001) J. Immunol. , vol.167 , pp. 6812-6820
    • Kim, E.Y.1    Teh, H.S.2
  • 52
    • 0037087341 scopus 로고    scopus 로고
    • TNF-TNFR2 interactions are critical for the development of intestinal graft-versus-host disease in MHC class II-disparate (C57BL/6J → C57BL/6J × bm12)F1 mice
    • G.R. Brown E. Lee D.L. Thiele TNF-TNFR2 interactions are critical for the development of intestinal graft-versus-host disease in MHC class II-disparate (C57BL/6J → C57BL/6J × bm12)F1 mice J. Immunol. 168 2002 3065 3071
    • (2002) J. Immunol. , vol.168 , pp. 3065-3071
    • Brown, G.R.1    Lee, E.2    Thiele, D.L.3
  • 53
    • 0035213540 scopus 로고    scopus 로고
    • Molecular aspects of iron absorption and HFE expression
    • S. Parkkila O. Niemela Molecular aspects of iron absorption and HFE expression Gastroenterology 121 2001 1489 1496
    • (2001) Gastroenterology , vol.121 , pp. 1489-1496
    • Parkkila, S.1    Niemela, O.2
  • 55
    • 0034672236 scopus 로고    scopus 로고
    • Iron homeostasis: New tales from the crypt
    • C.N. Roy C.A. Enns Iron homeostasis: New tales from the crypt Blood 96 2000 4020 4027
    • (2000) Blood , vol.96 , pp. 4020-4027
    • Roy, C.N.1    Enns, C.A.2


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