Phencyclidine exacerbates attentional deficits in a neurodevelopmental rat model of schizophrenia

Neuropsychopharmacology

Volumn 28, Issue 10, 2003, Pages 1799-1809

  Le Pen, Gwenaëlle Le ^a   Grottick, Andrew J ^b   Higgins, Guy A ^c   Moreau, Jean Luc ^c  

^a CENTRE PAUL BROCA   (France)

^b Arena Pharmaceutical Inc   (United States)

^c F HOFFMANN LA ROCHE LTD   (Switzerland)

Author keywords

Animal model; Attentional processes; Five choice serial reaction time task; Neonatal lesion; Schizophrenia; Ventral hippocampus

Indexed keywords

PHENCYCLIDINE; AMPHETAMINE; CENTRAL STIMULANT AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ATTENTION DEFICIT DISORDER; COGNITION; CONTROLLED STUDY; HIPPOCAMPUS; NERVE CELL DIFFERENTIATION; NONHUMAN; PRIORITY JOURNAL; RAT; SCHIZOPHRENIA; TASK PERFORMANCE; VISUAL ACUITY; AGING; ANIMAL; ANIMAL BEHAVIOR; ATTENTION; COMPARATIVE STUDY; DECISION MAKING; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECT; DRUG INTERACTION; GROWTH, DEVELOPMENT AND AGING; INJURY; MALE; MOTOR ACTIVITY; NEWBORN; PATHOLOGY; PATHOPHYSIOLOGY; REACTION TIME; SPRAGUE DAWLEY RAT;

AGING; AMPHETAMINE; ANIMALS; ANIMALS, NEWBORN; ATTENTION; ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; BEHAVIOR, ANIMAL; CENTRAL NERVOUS SYSTEM STIMULANTS; CHOICE BEHAVIOR; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; HIPPOCAMPUS; MALE; MOTOR ACTIVITY; PHENCYCLIDINE; RATS; RATS, SPRAGUE-DAWLEY; REACTION TIME; SCHIZOPHRENIA;

EID: 0642308242     PISSN: 0893133X     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.npp.1300208     Document Type: Article

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