Region specific changes in forebrain 5-hydroxytryptamine1a and 5-hydroxytryptamine2a receptors in isolation-reared rats: An in vitro autoradiography study

Neuroscience

Volumn 123, Issue 3, 2004, Pages 725-732

  Preece, M A ^a,c   Dalley, J W ^b   Theobald, D E H ^b   Robbins, T W ^b   Reynolds, G P ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b UK   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

Early life events; Monoamines; Prefrontal cortex; Schizophrenia; Serotonin; Social isolation

Indexed keywords

KETANSERIN; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; SEROTONIN 1A ANTAGONIST; SEROTONIN 1A RECEPTOR; SEROTONIN 2A ANTAGONIST; SEROTONIN 2A RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTORADIOGRAPHY; BINDING SITE; CINGULATE GYRUS; CONTROLLED STUDY; DENTATE GYRUS; FOREBRAIN; FRONTAL CORTEX; HIPPOCAMPUS; IN VITRO STUDY; MALE; MOTOR CORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SEROTONINERGIC SYSTEM; SOCIAL ADAPTATION; SOMATOSENSORY CORTEX;

EID: 0347990406     PISSN: 03064522     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuroscience.2003.10.008     Document Type: Article

References (63)

1. Bakshi V.P., Swerdlow N.R., Braff D.L., Geyer M.A. Reversal of isolation rearing-induced deficits in prepulse inhibition by Seroquel and olanzapine. Biol Psychiatry. 43:1998;436-445.
2. Bennett J.P. Jr, Enna S.J., Bylund D.B., Gillin J.C., Wyatt R.J., Snyder S.H. Neurotransmitter receptors in frontal cortex of schizophrenics. Arch Gen Psychiatry. 36:1979;927-934.
3. Bickerdike M.J., Wright I.K., Marsden C.A. Social isolation attenuates rat forebrain 5-HT release induced by KCI stimulation and exposure to a novel environment. Behav Pharmacol. 4:1993;231-236.
4. Blanc G., Herve D., Simon H., Lisoprawski A., Glowinski J., Tassin J.P. Response to stress of mesocortico-frontal dopaminergic neurones in rats after long-term isolation. Nature. 284:1980;265-267.
5. Braff D., Stone C., Callaway E., Geyer M., Glick I., Bali L. Prestimulus effects on human startle reflex in normals and schizophrenics. Psychophysiology. 15:1978;339-343.
6. Braff D.L., Geyer M.A. Sensorimotor gating and schizophrenia human and animal model studies . Arch Gen Psychiatry. 47:1990;181-188.
7. Braun K., Lange E., Metzger M., Poeggel G. Maternal separation followed by early social deprivation affects the development of monoaminergic fiber systems in the medial prefrontal cortex of Octodon degus. Neuroscience. 95:2000;309-318.
8. 2A receptor mRNAs and binding site densities are differentially altered in schizophrenia. Neuropsychopharmacology. 15:1996;442-455.
9. Cilia J., Reavill C., Hagan J.J., Jones D.N. Long-term evaluation of isolation-rearing induced prepulse inhibition deficits in rats. Psychopharmacology (Berl). 156:2001;327-337.
10. Dalley J.W., Theobald D.E., Eagle D.M., Passetti F., Robbins T.W. Deficits in impulse control associated with tonically-elevated serotonergic function in rat prefrontal cortex. Neuropsychopharmacology. 26:2002;716-728.
11. Dalley J.W., Theobald D.E., Li P.M.M.C., Pereira E.A.C., Robbins T.W. Specific abnormalities in serotonin release in the prefrontal cortex of isolation-reared rats on a task assessing visuo-spatial attention and impulsivity. Psychopharmacology (Berl). 164:2002;329-340.
12. Einon D.F., Morgan M.J. A critical period for social isolation in the rat. Dev Psychobiol. 10:1977;123-132.
13. 2 receptors are enriched on neocortical pyramidal neurones destroyed by intrastriatal volkensin. J Pharmacol Exp Ther. 261:1992;1273-1281.
14. Fone K.C., Shalders K., Fox Z.D., Arthur R., Marsden C.A. Increased 5-HT2C receptor responsiveness occurs on rearing rats in social isolation. Psychopharmacology (Berl). 123:1996;346-352.
15. Fulford A.J., Marsden C.A. Conditioned release of 5-hydroxytryptamine in vivo in the nucleus accumbens following isolation-rearing in the rat. Neuroscience. 83:1998;481-487.
16. Geyer M.A., Swerdlow N.R., Lehmann-Masten V., Teschendorf H.J., Traut M., Gross G. Effects of LU-111995 in three models of disrupted prepulse inhibition in rats. J Pharmacol Exp Ther. 290:1999;716-724.
17. Geyer M.A., Wilkinson L.S., Humby T., Robbins T.W. Isolation rearing of rats produces a deficit in prepulse inhibition of acoustic startle similar to that in schizophrenia. Biol Psychiatry. 34:1993;361-372.
18. Globus A., Rosenzweig M.R., Bennett E.L., Diamond M.C. Effects of differential experience on dendritic spine counts in rat cerebral cortex. J Comp Physiol Psychol. 82:1973;175-181.
19. Greenough W.T., Volkmar F.R., Juraska J.M. Effects of rearing complexity on dendritic branching in frontolateral and temporal cortex of the rat. Exp Neurol. 41:1973;371-378.
20. Hall F.S., Wilkinson L.S., Humby T., Inglis W., Kendall D.A., Marsden C.A., Robbins T.W. Isolation rearing in rats pre- and postsynaptic changes in striatal dopaminergic systems . Pharmacol Biochem Behav. 59:1998;859-872.
21. Hall F.S., Sundstrom J.M., Lerner J., Pert A. Enhanced corticosterone release after a modified forced swim test in Fawn hooded rats is independent of rearing experience. Pharmacol Biochem Behav. 69:2001;629-634.
22. 2A receptor in rat cerebral cortex and olfactory system revealed by immunohistochemistry using two antibodies raised in rabbit and chicken. Mol Brain Res. 54:1998;199-211.
23. 1A receptors in prefrontal and temporal cortices of brains from patients with chronic schizophrenia. Life Sci. 48:1991;355-363.
24. Heidbreder C.A., Foxton R., Cilia J., Hughes Z.A., Shah A.J., Atkins A., Hunter A.J., Hagan J.J., Jones D.N. Increased responsiveness of dopamine to atypical, but not typical antipsychotics in the medial prefrontal cortex of rats reared in isolation. Psychopharmacology (Berl). 156:2001;338-351.
25. Heidbreder C.A., Weiss I.C., Domeney A.M., Pryce C., Homberg J., Hedou G., Feldon J., Moran M.C., Nelson P. Behavioral, neurochemical and endocrinological characterization of the early social isolation syndrome. Neuroscience. 100:2000;749-768.
26. Hol T., Van den Berg C.L., Van Ree J.M., Spruijt B.M. Isolation during the play period in infancy decreases adult social interactions in rats. Behav Brain Res. 100:1999;91-97.
27. Holson R.R., Scallet A.C., Ali S.F., Sullivan P. Adrenocortical, beta-endorphin and behavioral responses to graded stressors in differentially reared rats. Physiol Behav. 42:1988;125-130.
28. (1A) receptor activation a possible mechanism of atypical antipsychotic-induced cortical dopamine release . J Neurochem. 76:2001;1521-1531.
29. (1A) receptor agonism . Brain Res. 956:2002;349-357.
30. 2A serotonin receptors in the primate cerebral cortex possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites . Proc Natl Acad Sci USA. 95:1998;735-740.
31. Joel D., Weiner I., Feldon J. Electrolytic lesions of the medial prefrontal cortex in rats disrupt performance on an analog of the Wisconsin Card Sorting Test, but do not disrupt latent inhibition implications for animal models of schizophrenia . Behav Brain Res. 85:1997;187-201.
32. Jones G.H., Hernandez T.D., Kendall D.A., Marsden C.A., Robbins T.W. Dopaminergic and serotonergic function following isolation rearing in rats study of behavioural responses and postmortem and in vivo neurochemistry . Pharmacol Biochem Behav. 43:1992;17-35.
33. Joyce J.N., Shane A., Lexow N., Winokur A., Casanova M.F., Kleinman J.E. Serotonin uptake sites and serotonin receptors are altered in the limbic system of schizophrenics. Neuropsychopharmacology. 8:1993;315-336.
34. 1A receptor antagonist. Brain Res. 673:1995;217-225.
35. 1A receptors in the rat central nervous system. J Comp Neurol. 365:1996;289-305.
36. (1A) receptors regional distribution and functional characteristics . Nucl Med Biol. 27:2000;429-435.
37. Lanier L.P., Isaacson R.L. Early developmental changes in the locomotor response to amphetamine and their relation to hippocampal function. Brain Res. 126:1977;567-575.
38. Lapiz M.D., Fulford A., Muchimapura S., Mason R., Parker T., Marsden C.A. Influence of postweaning social isolation in the rat on brain development, conditioned behaviour and neurotransmission. Ross Fiziol Zh Im. I:(M Sechenova 87):2001;730-751.
39. Laruelle M., Abi-Dargham A., Casanova M.F., Toti R., Weinberger D.R., Kleinman J.E. Selective abnormalities of prefrontal serotonergic receptors in schizophrenia a postmortem study . Arch Gen Psychiatry. 50:1993;810-818.
40. Matthews K., Dalley J.W., Matthews C., Tsai T.H., Robbins T.W. Periodic maternal separation of neonatal rats produces region- and gender-specific effects on biogenic amine content in postmortem adult brain. Synapse. 40:2001;1-10.
41. 2 receptor immunoreactivity in the developing rat brain. Neuroscience. 55:1993;869-880.
42. Muchimapura S., Fulford A.J., Mason R., Marsden C.A. Isolation rearing in the rat disrupts the hippocampal response to stress. Neuroscience. 112:2002;697-705.
43. Oehler J., Jahkel M., Schmidt J. Neuronal transmitter sensitivity after social isolation in rats. Physiol Behav. 41:1987;187-191.
44. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1986;Academic Press, New York.
45. Pazos A., Cortes R., Palacios J.M. Quantitative autoradiographic mapping of serotonin receptors in the rat brain II . Serotonin-. 2:(receptors. Brain Res 346):1985;231-249.
46. Poeggel G., Nowicki L., Braun K. Early social deprivation alters monoaminergic afferents in the orbital prefrontal cortex of Octodon degus. Neuroscience. 166:2003;617-620.
47. 1A receptor mRNA expression and binding in the rat hippocampus. Mol Brain Res. 53:1998;285-290.
48. 2 receptors and their involvement in schizophrenia and neuroleptic drug action. J Neural Transm Suppl. 18:1983;273-277.
49. Rilke O., Freier D., Jahkel M., Oehler J. Dynamic alterations of serotonergic metabolism and receptors during social isolation of low- and high-active mice. Pharmacol Biochem Behav. 59:1998;891-896.
50. Robbins T.W., Jones G.H., Wilkinson L.S. Behavioural and neurochemical effects of early social deprivation in the rat. J Psychopharmacology. 10:1996;39-47.
51. Sahakian B.J., Robbins T.W., Morgan M.J., Iversen S.D. The effects of psychomotor stimulants on stereotypy and locomotor activity in socially-deprived and control rats. Brain Res. 84:1975;195-205.
52. (1A) receptors in ventral prefrontal cortex in schizophrenia. Biol Psychiatry. 39:1996;919-928.
53. Swerdlow N.R., Geyer M.A., Braff D.L. Neural circuit regulation of prepulse inhibition of startle in the rat current knowledge and future challenges . Psychopharmacology (Berl). 156:2001;194-215.
54. Varty G.B., Braff D.L., Geyer M.A. Is there a critical developmental 'window' for isolation rearing-induced changes in prepulse inhibition of the acoustic startle response? Behav Brain Res. 100:1999;177-183.
55. Varty G.B., Marsden C.A., Higgins G.A. Reduced synaptophysin immunoreactivity in the dentate gyrus of prepulse inhibition-impaired isolation-reared rats. Brain Res. 824:1999;197-203.
56. 2 receptors and transport sites for serotonin. Brain Res. 615:1993;87-94.
57. Weiss I.C., Feldon J. Environmental animal models for sensorimotor gating deficiencies in schizophrenia a review . Psychopharmacology (Berl). 156:2001;305-326.
58. Whitaker-Azmitia P., Zhou F., Hobin J., Borella A. Isolation-rearing of rats produces deficits as adults in the serotonergic innervation of hippocampus. Peptides. 21:2000;1755-1759.
59. Wilkinson L.S., Killcross S.S., Humby T., Hall F.S., Geyer M.A., Robbins T.W. Social isolation in the rat produces developmentally specific deficits in prepulse inhibition of the acoustic startle response without disrupting latent inhibition. Neuropsychopharmacology. 10:1994;61-72.
60. Winterfeld K.T., Teuchert-Noodt G., Dawirs R.R. Social environment alters both ontogeny of dopamine innervation of the medial prefrontal cortex and maturation of working memory in gerbils (Meriones unguiculatus). J Neurosci Res. 52:1998;201-209.
61. Wright I.K., Ismail H., Upton N., Marsden C.A. Effect of isolation-rearing on performance in the elevated plus maze and open field behaviour. Br J Pharmacol. 100:1990;375P.
62. Wright I.K., Ismail H., Upton N., Marsden C.A. Effect of isolation rearing on 5-HT agonist-induced responses in the rat. Psychopharmacology (Berl). 105:1991;259-263.
63. (2A)) receptors in the rat brain. Brain Res Bull. 51:2000;499-505.