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Volumn 10, Issue 1, 1996, Pages 39-47

Behavioural and neurochemical effects of early social deprivation in the rat

Author keywords

5 HT; Cognition; Dopamine; Hyperactivity; Isolation rearing; Nucleus accumbens; Reward; Social experience; Striatum

Indexed keywords

AMINE; AMPHETAMINE; DOPAMINE; SEROTONIN;

EID: 0029879274     PISSN: 02698811     EISSN: None     Source Type: Journal    
DOI: 10.1177/026988119601000107     Document Type: Article
Times cited : (135)

References (49)
  • 1
    • 0023814840 scopus 로고
    • Differential performance of acute and chronic schizophrenics in a latent inhibition task
    • Baruch I, Hemsley D, Gray J A (1988) Differential performance of acute and chronic schizophrenics in a latent inhibition task. J Nerv Ment Disord 176: 598-606
    • (1988) J Nerv Ment Disord , vol.176 , pp. 598-606
    • Baruch, I.1    Hemsley, D.2    Gray, J.A.3
  • 2
    • 0026145183 scopus 로고
    • Associative processes in differentially reared rhesus monkeys (Macaca mulatta)
    • Beauchamp A J, Gluck J P, Fouty H E, Lewis M H (1991) Associative processes in differentially reared rhesus monkeys (Macaca mulatta). Devel Psychobiol 24: 175-189
    • (1991) Devel Psychobiol , vol.24 , pp. 175-189
    • Beauchamp, A.J.1    Gluck, J.P.2    Fouty, H.E.3    Lewis, M.H.4
  • 3
    • 0027233562 scopus 로고
    • Social isolation attenuates rat forebrain 5-HT release induced by KCl stimulation and exposure to a novel environment
    • Bickerdike M J, Wright I K, Marsden C A (1993) Social isolation attenuates rat forebrain 5-HT release induced by KCl stimulation and exposure to a novel environment. Behav Pharmacol 4: 231-236
    • (1993) Behav Pharmacol , vol.4 , pp. 231-236
    • Bickerdike, M.J.1    Wright, I.K.2    Marsden, C.A.3
  • 4
    • 0019223568 scopus 로고
    • Response to stress; mesocortical-frontal dopaminergic neurons in rats after long-term social isolation
    • Blanc G, Herve D, Simon H, Lisoprawski A, Glowinski J, Tassin J P (1980) Response to stress; mesocortical-frontal dopaminergic neurons in rats after long-term social isolation. Nature 284: 265-267
    • (1980) Nature , vol.284 , pp. 265-267
    • Blanc, G.1    Herve, D.2    Simon, H.3    Lisoprawski, A.4    Glowinski, J.5    Tassin, J.P.6
  • 5
    • 0000026020 scopus 로고
    • Sensorimotor gating and schizophrenia: Human and animal model studies
    • Braff D L, Geyer M A (1990) Sensorimotor gating and schizophrenia: human and animal model studies. Arch Gen Psychiatr 49: 206-215
    • (1990) Arch Gen Psychiatr , vol.49 , pp. 206-215
    • Braff, D.L.1    Geyer, M.A.2
  • 6
    • 0011955754 scopus 로고
    • Schizophrenia: Nature of the disease process and its biological correlates
    • Plum F (ed.), The Chemical Press, New York
    • Crow T J, Johnstone E C (1988) Schizophrenia: nature of the disease process and its biological correlates. In Plum F (ed.), Handbook of physiology V. The nervous system. The Chemical Press, New York, pp. 843-869
    • (1988) Handbook of Physiology V. The Nervous System , pp. 843-869
    • Crow, T.J.1    Johnstone, E.C.2
  • 7
    • 0019046786 scopus 로고
    • Spatial memory and response strategies in rats: Age, sex and rearing differences in performance
    • Einon D F (1980) Spatial memory and response strategies in rats: age, sex and rearing differences in performance. Q J Exp Psychol 32: 473-489
    • (1980) Q J Exp Psychol , vol.32 , pp. 473-489
    • Einon, D.F.1
  • 8
    • 0017408532 scopus 로고
    • A critical period for social isolation in the rat
    • Einon D F, Morgan M J (1977) A critical period for social isolation in the rat. Devel Psychobiol 10: 123-132
    • (1977) Devel Psychobiol , vol.10 , pp. 123-132
    • Einon, D.F.1    Morgan, M.J.2
  • 9
    • 0017935496 scopus 로고
    • Early isolation produces enduring hyperactivity in the rat, but no effect upon spontaneous alternation
    • Einon D F, Morgan M J (1978) Early isolation produces enduring hyperactivity in the rat, but no effect upon spontaneous alternation. Q J Exp Psychol 30: 151-156
    • (1978) Q J Exp Psychol , vol.30 , pp. 151-156
    • Einon, D.F.1    Morgan, M.J.2
  • 10
    • 0018366688 scopus 로고
    • Environmentally induced differences in susceptibility of rats to CNS stimulants and CNS depressants: Evidence against a unitary explanation
    • Einon D F, Sahakian B J (1979) Environmentally induced differences in susceptibility of rats to CNS stimulants and CNS depressants: evidence against a unitary explanation. Psychopharmacology 61: 299-307
    • (1979) Psychopharmacology , vol.61 , pp. 299-307
    • Einon, D.F.1    Sahakian, B.J.2
  • 11
    • 0016714111 scopus 로고
    • Chlordiazepoxide and isolation-induced timidity in rats
    • Berl.
    • Einon D F, Tye N C (1975) Chlordiazepoxide and isolation-induced timidity in rats. Psychopharmacologia (Berl.) 44: 85-88
    • (1975) Psychopharmacologia , vol.44 , pp. 85-88
    • Einon, D.F.1    Tye, N.C.2
  • 12
    • 0017150356 scopus 로고
    • The effects of isolation on barbiturate-induced anaesthesia in the rat
    • Einon D F, Stewart J, Atkinson S, Morgan M J (1976) The effects of isolation on barbiturate-induced anaesthesia in the rat. Psychopharmacology 50: 85-88
    • (1976) Psychopharmacology , vol.50 , pp. 85-88
    • Einon, D.F.1    Stewart, J.2    Atkinson, S.3    Morgan, M.J.4
  • 13
    • 0017875079 scopus 로고
    • Exploration, distraction and habituation in rats reared in isolation
    • File S E (1978) Exploration, distraction and habituation in rats reared in isolation. Devel Psychobiol 11: 73-81
    • (1978) Devel Psychobiol , vol.11 , pp. 73-81
    • File, S.E.1
  • 14
    • 0019828960 scopus 로고
    • Locomotor activity, defecation score and corticosterone levels during open field exposure: A comparison among individually and group-housed rats, and genetically selected rat lines
    • Gentsch C, Lichtsteiner M, Feer H (1991) Locomotor activity, defecation score and corticosterone levels during open field exposure: a comparison among individually and group-housed rats, and genetically selected rat lines. Physiol Behav 27: 183-186
    • (1991) Physiol Behav , vol.27 , pp. 183-186
    • Gentsch, C.1    Lichtsteiner, M.2    Feer, H.3
  • 15
    • 0023923987 scopus 로고
    • Isolation-induced locomotor hyperactivity and hypoalgesia in rats are prevented by handling and reversed by resocialization
    • Gentsch C, Lichtsteiner M, Prishknecht H R, Feer H, Siegfried B (1988) Isolation-induced locomotor hyperactivity and hypoalgesia in rats are prevented by handling and reversed by resocialization. Physiol Behav 43: 13-16
    • (1988) Physiol Behav , vol.43 , pp. 13-16
    • Gentsch, C.1    Lichtsteiner, M.2    Prishknecht, H.R.3    Feer, H.4    Siegfried, B.5
  • 16
    • 0027515470 scopus 로고
    • Isolation-rearing of rats produces a deficit in pre-pulse inhibition of acoustic startle similar to that in schizophrenia
    • Geyer M, Wilkinson L S, Humby T, Robbins T W (1993) Isolation-rearing of rats produces a deficit in pre-pulse inhibition of acoustic startle similar to that in schizophrenia. Biol Psychiatr 34: 361-372
    • (1993) Biol Psychiatr , vol.34 , pp. 361-372
    • Geyer, M.1    Wilkinson, L.S.2    Humby, T.3    Robbins, T.W.4
  • 18
    • 0019309892 scopus 로고
    • Increased receptor binding in the striatum of rats after long term isolation
    • Guisado E, Fernandez-Tome P, Garzon J, Del Rio J (1980) Increased receptor binding in the striatum of rats after long term isolation. Eur J Pharmacol 65: 463-464
    • (1980) Eur J Pharmacol , vol.65 , pp. 463-464
    • Guisado, E.1    Fernandez-Tome, P.2    Garzon, J.3    Del Rio, J.4
  • 19
    • 0015115203 scopus 로고
    • From thought to therapy: Lessons from a primate laboratory
    • Harlow H F, Harlow M K, Suomi S J (1971) From thought to therapy: lessons from a primate laboratory. Am Sci 59: 538-549
    • (1971) Am Sci , vol.59 , pp. 538-549
    • Harlow, H.F.1    Harlow, M.K.2    Suomi, S.J.3
  • 20
    • 0024582145 scopus 로고
    • Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats
    • Jones G H, Robbins T W, Marsden C A (1989) Isolation-rearing retards the acquisition of schedule-induced polydipsia in rats. Physiol Behav 45: 71-78
    • (1989) Physiol Behav , vol.45 , pp. 71-78
    • Jones, G.H.1    Robbins, T.W.2    Marsden, C.A.3
  • 21
    • 0025007262 scopus 로고
    • Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: Possible disruption of dopamine-dependent mechanisms of the nucleus accumbens
    • Jones G H, Marsden C A, Robbins T W (1990) Increased sensitivity to amphetamine and reward-related stimuli following social isolation in rats: possible disruption of dopamine-dependent mechanisms of the nucleus accumbens. Psychopharmacology 102: 364-372
    • (1990) Psychopharmacology , vol.102 , pp. 364-372
    • Jones, G.H.1    Marsden, C.A.2    Robbins, T.W.3
  • 22
    • 0025907854 scopus 로고
    • Behavioural rigidity and rule-learning deficits following social isolation in rats: Neurochemical correlates
    • Jones G H, Marsden C A, Robbins T W (1992) Behavioural rigidity and rule-learning deficits following social isolation in rats: neurochemical correlates. Behav Brain Res 43: 35-50
    • (1992) Behav Brain Res , vol.43 , pp. 35-50
    • Jones, G.H.1    Marsden, C.A.2    Robbins, T.W.3
  • 23
    • 0026671676 scopus 로고
    • Dopaminergic and serotonergic function following isolation-rearing in rats: Study of behavioural responses and post mortem and in vivo neurochemistry
    • Jones G H, Hernandez T D, Kendall D A, Marsden C A, Bobbins T W (1992) Dopaminergic and serotonergic function following isolation-rearing in rats: study of behavioural responses and post mortem and in vivo neurochemistry. Pharmacol Biochem Behav 43: 17-35
    • (1992) Pharmacol Biochem Behav , vol.43 , pp. 17-35
    • Jones, G.H.1    Hernandez, T.D.2    Kendall, D.A.3    Marsden, C.A.4    Bobbins, T.W.5
  • 24
    • 0014969821 scopus 로고
    • Long-term isolation in rats reduces the morphine response
    • Katz D M, Steinberg H (1970) Long-term isolation in rats reduces the morphine response. Nature 228: 469-471
    • (1970) Nature , vol.228 , pp. 469-471
    • Katz, D.M.1    Steinberg, H.2
  • 25
    • 0016826092 scopus 로고
    • Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and olfactory tubercle in the rat
    • Kelly P H, Seviour P W, Iversen S D (1975) Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and olfactory tubercle in the rat. Brain Res 94: 507-522
    • (1975) Brain Res , vol.94 , pp. 507-522
    • Kelly, P.H.1    Seviour, P.W.2    Iversen, S.D.3
  • 26
    • 0027459312 scopus 로고
    • Differential effects of intraaccumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm
    • Killcross A S, Robbins T W (1993) Differential effects of intraaccumbens and systemic amphetamine on latent inhibition using an on-baseline, within-subject conditioned suppression paradigm. Psychopharmacology 110: 479-489
    • (1993) Psychopharmacology , vol.110 , pp. 479-489
    • Killcross, A.S.1    Robbins, T.W.2
  • 27
    • 0025212518 scopus 로고
    • Long-term effects of early social isolation in Macaca mulatta: Changes in dopamine receptor function following apomorphine challenge
    • Lewis M H, Gluck J P, Beauchamp A J, Keresztury M F, Mailman R B (1989) Long-term effects of early social isolation in Macaca mulatta: changes in dopamine receptor function following apomorphine challenge. Brain Res 513: 67-73
    • (1989) Brain Res , vol.513 , pp. 67-73
    • Lewis, M.H.1    Gluck, J.P.2    Beauchamp, A.J.3    Keresztury, M.F.4    Mailman, R.B.5
  • 29
    • 0025840188 scopus 로고
    • Social deprivation of infant rhesus monkeys alters the chemoarchitecture of the brain: I subcortical regions
    • Martin L J, Spicer D M, Lewis M H, Gluck J P, Cork L C (1991) Social deprivation of infant rhesus monkeys alters the chemoarchitecture of the brain: I subcortical regions. J Neurosci 11: 3344-3358
    • (1991) J Neurosci , vol.11 , pp. 3344-3358
    • Martin, L.J.1    Spicer, D.M.2    Lewis, M.H.3    Gluck, J.P.4    Cork, L.C.5
  • 30
    • 0015853502 scopus 로고
    • Effects of post-weaning environment on learning in the rat
    • Morgan M J (1973) Effects of post-weaning environment on learning in the rat. Anim Behav 21: 429-442
    • (1973) Anim Behav , vol.21 , pp. 429-442
    • Morgan, M.J.1
  • 31
    • 0016727753 scopus 로고
    • Incentive motivation and behavioural inhibition in socially-isolated rats
    • Morgan M J, Einon D F (1975) Incentive motivation and behavioural inhibition in socially-isolated rats. Physiol Behav 15: 405-409
    • (1975) Physiol Behav , vol.15 , pp. 405-409
    • Morgan, M.J.1    Einon, D.F.2
  • 32
    • 0017340119 scopus 로고
    • Inhibition and isolation rearing in the rat: Extinction and satiation
    • Morgan M J, Einon D F, Morris R G M (1977) Inhibition and isolation rearing in the rat: extinction and satiation. Physiol Behav 18: 1-16
    • (1977) Physiol Behav , vol.18 , pp. 1-16
    • Morgan, M.J.1    Einon, D.F.2    Morris, R.G.M.3
  • 33
    • 0028361966 scopus 로고
    • Isolation-rearing enhances the locomotor response both to a novel environment and to cocaine, but impairs the intravenous self-administration of cocaine
    • Phillips G D, Howes S R, Whitelaw R B, Wilkinson L, Robbins T W, Everitt B J (1994a) Isolation-rearing enhances the locomotor response both to a novel environment and to cocaine, but impairs the intravenous self-administration of cocaine. Psychopharmacology 115: 407-418
    • (1994) Psychopharmacology , vol.115 , pp. 407-418
    • Phillips, G.D.1    Howes, S.R.2    Whitelaw, R.B.3    Wilkinson, L.4    Robbins, T.W.5    Everitt, B.J.6
  • 34
    • 0028277917 scopus 로고
    • Isolation-rearing impairs the reinforcing efficacy of intravenous cocaine of intra-accumbens D-amphetamine: Impaired response to intra-accumbens D1 and D2/3 dopamine receptor antagonists
    • Phillips G D, Whitelaw E B, Howes S R, Robbing T W, Everitt B J (1994b) Isolation-rearing impairs the reinforcing efficacy of intravenous cocaine of intra-accumbens D-amphetamine: impaired response to intra-accumbens D1 and D2/3 dopamine receptor antagonists. Psychopharmacology 115: 419-429
    • (1994) Psychopharmacology , vol.115 , pp. 419-429
    • Phillips, G.D.1    Whitelaw, E.B.2    Howes, S.R.3    Robbing, T.W.4    Everitt, B.J.5
  • 35
    • 0001571597 scopus 로고
    • Enriched environments: Facts, factors and fantasies
    • Petrinovich L, McGaugh J L (eds), Plenum Press, New York
    • Rosenzwieg M H, Bennett E L (1976) Enriched environments: facts, factors and fantasies. In Petrinovich L, McGaugh J L (eds), Knowing, thinking and believing. Plenum Press, New York, pp. 179-213
    • (1976) Knowing, Thinking and Believing , pp. 179-213
    • Rosenzwieg, M.H.1    Bennett, E.L.2
  • 37
    • 0017352101 scopus 로고
    • Isolation-rearing enhances tail-pinch induced oral behaviour in rats
    • Sahakian B J, Bobbins T W (1977) Isolation-rearing enhances tail-pinch induced oral behaviour in rats. Physiol Behav 18: 53-58
    • (1977) Physiol Behav , vol.18 , pp. 53-58
    • Sahakian, B.J.1    Bobbins, T.W.2
  • 38
    • 0016427881 scopus 로고
    • The effects of psychomotor stimulants on stereotypy and locomotor activity in socially deprived and control rats
    • Sahakian B J, Robbins T W, Morgan M J, Ivesen S D (1975) The effects of psychomotor stimulants on stereotypy and locomotor activity in socially deprived and control rats. Brain Res 84: 195-205
    • (1975) Brain Res , vol.84 , pp. 195-205
    • Sahakian, B.J.1    Robbins, T.W.2    Morgan, M.J.3    Ivesen, S.D.4
  • 40
    • 0026036186 scopus 로고
    • The effects of spiperone, SCH 23390, and clozapine on apomorphine-inhibition of sensorimotor gating of the startle response in the rat
    • Swerdlow N R, Keith V A, Braff D L, Geyer M A (1991) The effects of spiperone, SCH 23390, and clozapine on apomorphine-inhibition of sensorimotor gating of the startle response in the rat. J Pharmacol Exp Ther 256: 530-536
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 530-536
    • Swerdlow, N.R.1    Keith, V.A.2    Braff, D.L.3    Geyer, M.A.4
  • 41
    • 0026690995 scopus 로고
    • Neural substrates of sensorimotor gating of the startle reflex: Preclinical findings and their implications
    • Swerdlow N R, Caine S B, Braff D L, Geyer M (1992) Neural substrates of sensorimotor gating of the startle reflex: preclinical findings and their implications. J Psychopharmacol 6: 176-190
    • (1992) J Psychopharmacol , vol.6 , pp. 176-190
    • Swerdlow, N.R.1    Caine, S.B.2    Braff, D.L.3    Geyer, M.4
  • 42
    • 0017642490 scopus 로고
    • The effect of isolation on catecholamine concentration and turnover in discrete areas of the rat brain
    • Thoa T B, Tizabi Y, Jacobowitz D M (1977) The effect of isolation on catecholamine concentration and turnover in discrete areas of the rat brain. Brain Res 13: 259-269
    • (1977) Brain Res , vol.13 , pp. 259-269
    • Thoa, T.B.1    Tizabi, Y.2    Jacobowitz, D.M.3
  • 43
    • 0002966531 scopus 로고
    • Measurement of neurotransmitter release by intracranial dialysis
    • Marsden C A (ed.), Wiley, Chichester
    • Ungerstedt U (1984) Measurement of neurotransmitter release by intracranial dialysis. In Marsden C A (ed.), Measurement of neurotransmitter release in vivo. Wiley, Chichester, pp. 81-107
    • (1984) Measurement of Neurotransmitter Release in Vivo , pp. 81-107
    • Ungerstedt, U.1
  • 44
    • 0021263575 scopus 로고
    • Abolition of the expression, but not the acquisition, of latent inhibition by chronic amphetamine in the rat
    • Weiner I, Lubow R E, Feldon J (1984) Abolition of the expression, but not the acquisition, of latent inhibition by chronic amphetamine in the rat. Psychopharmacology 83: 194-199
    • (1984) Psychopharmacology , vol.83 , pp. 194-199
    • Weiner, I.1    Lubow, R.E.2    Feldon, J.3
  • 45
    • 0017887331 scopus 로고
    • Changes in brain catecholamine turnover and receptor sensitivity induced by social deprivation in rats
    • Weinstock M, Speiser Z, Ashkenazi R (1978) Changes in brain catecholamine turnover and receptor sensitivity induced by social deprivation in rats. Psychopharmacology 56: 205-209
    • (1978) Psychopharmacology , vol.56 , pp. 205-209
    • Weinstock, M.1    Speiser, Z.2    Ashkenazi, R.3
  • 46
    • 0028265817 scopus 로고
    • Social isolation produces developmentally-specific deficits in pre-pulse inhibition of the acoustic startle response but does not disrupt latent inhibition
    • Wilkinson L S, Killcross A S, Humby T, Hall F S, Geyer M A, Robbins T W (1994) Social isolation produces developmentally-specific deficits in pre-pulse inhibition of the acoustic startle response but does not disrupt latent inhibition. Neurospychopharmacology 10: 61-72
    • (1994) Neurospychopharmacology , vol.10 , pp. 61-72
    • Wilkinson, L.S.1    Killcross, A.S.2    Humby, T.3    Hall, F.S.4    Geyer, M.A.5    Robbins, T.W.6
  • 48
    • 0006544916 scopus 로고
    • Effect of isolation-rearing on performance in the elevated plus-maze and open field behaviour
    • Wright I K, Ismail H, Upton N, Marsden C A (1990) Effect of isolation-rearing on performance in the elevated plus-maze and open field behaviour. Br J Pharmacol 100: 375P
    • (1990) Br J Pharmacol , vol.100
    • Wright, I.K.1    Ismail, H.2    Upton, N.3    Marsden, C.A.4
  • 49
    • 0025861675 scopus 로고
    • Effect of isolation-rearing on 5-HT agonist responses in the rat
    • Wright I K, Ismail H, Upton N, Marsden C A (1991) Effect of isolation-rearing on 5-HT agonist responses in the rat. Psychopharmacology 105: 259-263
    • (1991) Psychopharmacology , vol.105 , pp. 259-263
    • Wright, I.K.1    Ismail, H.2    Upton, N.3    Marsden, C.A.4


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