-
1
-
-
0031570526
-
The clinical investigator: Bewitched, bothered, and bewildered - but still beloved
-
Goldstein JL, Brown MS. The clinical investigator: bewitched, bothered, and bewildered - but still beloved. J Clin Invest 1997;99:2803-12.
-
(1997)
J Clin Invest
, vol.99
, pp. 2803-2812
-
-
Goldstein, J.L.1
Brown, M.S.2
-
2
-
-
0000107028
-
Genetic markers for atherosclerosis and related risk factors
-
Lusis AJ, Rotter JI, Sparkes RS, editors. Basel: Karger
-
Mehrabian M, Lusis AJ. Genetic markers for atherosclerosis and related risk factors. In: Lusis AJ, Rotter JI, Sparkes RS, editors. Molecular Genetics of Coronary Artery Disease: Candidate Genes and Processes in Atherosclerosis. Basel: Karger, 1992:363-418.
-
(1992)
Molecular Genetics of Coronary Artery Disease: Candidate Genes and Processes in Atherosclerosis
, pp. 363-418
-
-
Mehrabian, M.1
Lusis, A.J.2
-
3
-
-
0030823635
-
Candidate genes, small effects, and the prediction of atherosclerosis
-
Hegele RA. Candidate genes, small effects, and the prediction of atherosclerosis. Crit Rev Clin Lab Sci 1997;34:343-67.
-
(1997)
Crit Rev Clin Lab Sci
, vol.34
, pp. 343-367
-
-
Hegele, R.A.1
-
4
-
-
0028090414
-
Genetic dissection of complex traits
-
Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-48.
-
(1994)
Science
, vol.265
, pp. 2037-2048
-
-
Lander, E.S.1
Schork, N.J.2
-
5
-
-
0031442316
-
Hepatic lipase gene polymorphisms influence plasma HDL levels
-
Murtomaki S, Tahvanainen E, Antikainen M, Tiret L, Nicaud V, Jansen H, Ehnholm C. Hepatic lipase gene polymorphisms influence plasma HDL levels. Arterioscler Thromb Vasc Biol 1997;1879-1884.
-
(1997)
Arterioscler Thromb Vasc Biol
, pp. 1879-1884
-
-
Murtomaki, S.1
Tahvanainen, E.2
Antikainen, M.3
Tiret, L.4
Nicaud, V.5
Jansen, H.6
Ehnholm, C.7
-
6
-
-
0030935065
-
A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol
-
Guerra R, Wang J, Grundy SM, Cohen JC. A hepatic lipase (LIPC) allele associated with high plasma concentrations of high density lipoprotein cholesterol. Proc Natl Acad Sci USA 1997;94:4532-7.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 4532-4537
-
-
Guerra, R.1
Wang, J.2
Grundy, S.M.3
Cohen, J.C.4
-
7
-
-
0031442667
-
Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients
-
Jansen H, Verhoeven AJM, Weeks L, Kastelein JJP, Halley DJJ, van den Ouweland A, Jukema JW, Seidell JC, Birkenhager JC. Common C-to-T substitution at position -480 of the hepatic lipase promoter associated with a lowered lipase activity in coronary artery disease patients. Arterioscler Thromb Vasc Biol 1997;17:2837-42.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 2837-2842
-
-
Jansen, H.1
Verhoeven, A.J.M.2
Weeks, L.3
Kastelein, J.J.P.4
Halley, D.J.J.5
Van Den Ouweland, A.6
Jukema, J.W.7
Seidell, J.C.8
Birkenhager, J.C.9
-
8
-
-
2642714137
-
Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. the LOCAT Study Investigators
-
Tahvanainen E, Syvanne M, Frick MH, Murtomaki-Repo S, Antikainen M, Kesaniemi YA, Kauma H, Pasternak A, Taskinen MR, Ehnholm C. Association of variation in hepatic lipase activity with promoter variation in the hepatic lipase gene. The LOCAT Study Investigators. J Clin Invest 1998;101:956-60.
-
(1998)
J Clin Invest
, vol.101
, pp. 956-960
-
-
Tahvanainen, E.1
Syvanne, M.2
Frick, M.H.3
Murtomaki-Repo, S.4
Antikainen, M.5
Kesaniemi, Y.A.6
Kauma, H.7
Pasternak, A.8
Taskinen, M.R.9
Ehnholm, C.10
-
9
-
-
0031929702
-
Hepatic lipase activity is lower in African American men than in white American men: Effects of the 5′ flanking polymorphism in the hepatic lipase gene
-
Vega GL, Clark LT, Tang A, Marcovina S, Grundy SM, Cohen JC. Hepatic lipase activity is lower in African American men than in white American men: effects of the 5′ flanking polymorphism in the hepatic lipase gene. J Lipid Res 1998;39:228-32.
-
(1998)
J Lipid Res
, vol.39
, pp. 228-232
-
-
Vega, G.L.1
Clark, L.T.2
Tang, A.3
Marcovina, S.4
Grundy, S.M.5
Cohen, J.C.6
-
10
-
-
0024468864
-
Structure of the human hepatic triglyceride lipase gene
-
Cai SJ, Wong DM, Chen SH, Chan L. Structure of the human hepatic triglyceride lipase gene. Biochemistry 1989;28:8966-71.
-
(1989)
Biochemistry
, vol.28
, pp. 8966-8971
-
-
Cai, S.J.1
Wong, D.M.2
Chen, S.H.3
Chan, L.4
-
11
-
-
0027993243
-
A polymorphism of the angiotensinogen gene is associated with variation in blood pressure in a genetic isolate
-
Hegele RA, Brunt JH, Connelly PW. A polymorphism of the angiotensinogen gene is associated with variation in blood pressure in a genetic isolate. Circulation 1994;90:2207-12.
-
(1994)
Circulation
, vol.90
, pp. 2207-2212
-
-
Hegele, R.A.1
Brunt, J.H.2
Connelly, P.W.3
-
12
-
-
0028175553
-
A gene-gender interaction affecting lipoproteins in a genetic isolate
-
Hegele RA, Evans AJ, Tu L, Ip G, Brunt JH, Connelly PW. A gene-gender interaction affecting lipoproteins in a genetic isolate. Arterioscler Thromb 1994;14:671-8.
-
(1994)
Arterioscler Thromb
, vol.14
, pp. 671-678
-
-
Hegele, R.A.1
Evans, A.J.2
Tu, L.3
Ip, G.4
Brunt, J.H.5
Connelly, P.W.6
-
13
-
-
0028900876
-
A polymorphism of the paraoxonase gene associated with variation in plasma lipoproteins in a genetic isolate
-
Hegele RA, Brunt JH, Connelly PW. A polymorphism of the paraoxonase gene associated with variation in plasma lipoproteins in a genetic isolate. Arterioscler Thromb Vasc Biol 1995;15:89-95.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 89-95
-
-
Hegele, R.A.1
Brunt, J.H.2
Connelly, P.W.3
-
14
-
-
0029011726
-
Multiple genetic determinants of variation of plasma lipoproteins in Alberta Hutterites
-
Hegele RA, Brunt JH, Connelly PW. Multiple genetic determinants of variation of plasma lipoproteins in Alberta Hutterites. Arterioscler Thromb Vasc Biol 1995;15:861-71.
-
(1995)
Arterioscler Thromb Vasc Biol
, vol.15
, pp. 861-871
-
-
Hegele, R.A.1
Brunt, J.H.2
Connelly, P.W.3
-
15
-
-
0029098068
-
Genetic variation on chromosome 1 associated with variation in body fat distribution in men
-
Hegele RA, Brunt JH, Connelly PW. Genetic variation on chromosome 1 associated with variation in body fat distribution in men. Circulation 1995;92:1089-93.
-
(1995)
Circulation
, vol.92
, pp. 1089-1093
-
-
Hegele, R.A.1
Brunt, J.H.2
Connelly, P.W.3
-
17
-
-
0030027930
-
Genetic and biochemical factors associated with variation in blood pressure in a genetic isolate
-
Hegele RA, Brunt JH, Connelly PW. Genetic and biochemical factors associated with variation in blood pressure in a genetic isolate. Hypertension 1996;27:308-12.
-
(1996)
Hypertension
, vol.27
, pp. 308-312
-
-
Hegele, R.A.1
Brunt, J.H.2
Connelly, P.W.3
-
18
-
-
0031024773
-
The prevalence of NIDDM and associated risk factors in native Canadians
-
Harris SB, Gittelsohn J, Hanley AJG, Barnie A, Wolever TMS, Gao J, Logan A, Zinman B. The prevalence of NIDDM and associated risk factors in native Canadians. Diabetes Care 1997;20:185-97.
-
(1997)
Diabetes Care
, vol.20
, pp. 185-197
-
-
Harris, S.B.1
Gittelsohn, J.2
Hanley, A.J.G.3
Barnie, A.4
Wolever, T.M.S.5
Gao, J.6
Logan, A.7
Zinman, B.8
-
19
-
-
0029823857
-
Genetic variation of intestinal fatty acid-binding protein associated with variation in body mass in aboriginal Canadians
-
Hegele RA, Harris SB, Hanley AJ, Sadikian S, Connelly PW, Zinman B. Genetic variation of intestinal fatty acid-binding protein associated with variation in body mass in aboriginal Canadians. J Clin Endocrinol Metab 1996;81:4334-7.
-
(1996)
J Clin Endocrinol Metab
, vol.81
, pp. 4334-4337
-
-
Hegele, R.A.1
Harris, S.B.2
Hanley, A.J.3
Sadikian, S.4
Connelly, P.W.5
Zinman, B.6
-
20
-
-
0030983832
-
Paraoxonase-2 gene (PON2) G148 variant associated with elevated fasting plasma glucose in noninsulin-dependent diabetes mellitus
-
Hegele RA, Connelly PW, Scherer SW, Hanley AJ, Harris SB, Tsui LC, Zinman B. Paraoxonase-2 gene (PON2) G148 variant associated with elevated fasting plasma glucose in noninsulin-dependent diabetes mellitus. J Clin Endocrinol Metab 1997;82:3373-7.
-
(1997)
J Clin Endocrinol Metab
, vol.82
, pp. 3373-3377
-
-
Hegele, R.A.1
Connelly, P.W.2
Scherer, S.W.3
Hanley, A.J.4
Harris, S.B.5
Tsui, L.C.6
Zinman, B.7
-
21
-
-
0343923422
-
Paraoxonase-2 G148 variant in an aboriginal Canadian girl with non-insulin-dependent diabetes
-
Hegele RA, Connelly PW, Scherer SW, Hanley AJ, Harris SB, Tsui LC, Zinman B. Paraoxonase-2 G148 variant in an aboriginal Canadian girl with non-insulin-dependent diabetes. Lancet 1997;350:785.
-
(1997)
Lancet
, vol.350
, pp. 785
-
-
Hegele, R.A.1
Connelly, P.W.2
Scherer, S.W.3
Hanley, A.J.4
Harris, S.B.5
Tsui, L.C.6
Zinman, B.7
-
22
-
-
0030945730
-
A common mtDNA polymorphism associated with variation in plasma triglyceride concentration
-
Hegele RA, Zinman B, Hanley AJ, Harris S, Connelly PW. A common mtDNA polymorphism associated with variation in plasma triglyceride concentration. Am J Hum Genet 1997;60:1552-5.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 1552-1555
-
-
Hegele, R.A.1
Zinman, B.2
Hanley, A.J.3
Harris, S.4
Connelly, P.W.5
-
23
-
-
0030980340
-
Common genomic variants associated with variation in plasma lipoproteins in young aboriginal Canadians
-
Hegele RA, Connelly PW, Hanley AJ, Sun F, Harris SB, Zinman B. Common genomic variants associated with variation in plasma lipoproteins in young aboriginal Canadians. Arterioscler Thromb Vasc Biol 1997;17:1060-6.
-
(1997)
Arterioscler Thromb Vasc Biol
, vol.17
, pp. 1060-1066
-
-
Hegele, R.A.1
Connelly, P.W.2
Hanley, A.J.3
Sun, F.4
Harris, S.B.5
Zinman, B.6
-
24
-
-
0030954135
-
Angiotensinogen gene variation associated with variation in blood pressure in aboriginal Canadians
-
Hegele RA, Harris SB, Hanley AJ, Sun F, Connelly PW, Zinman B. Angiotensinogen gene variation associated with variation in blood pressure in aboriginal Canadians. Hypertension 1997;29:1073-7.
-
(1997)
Hypertension
, vol.29
, pp. 1073-1077
-
-
Hegele, R.A.1
Harris, S.B.2
Hanley, A.J.3
Sun, F.4
Connelly, P.W.5
Zinman, B.6
-
25
-
-
0030923951
-
Are Canadian Inuit at increased genetic risk for coronary heart disease?
-
Hegele RA, Young TK, Connelly PW. Are Canadian Inuit at increased genetic risk for coronary heart disease? J Mol Med 1997;75:364-70.
-
(1997)
J Mol Med
, vol.75
, pp. 364-370
-
-
Hegele, R.A.1
Young, T.K.2
Connelly, P.W.3
-
26
-
-
0030938481
-
V677 mutation of methylene-tetrahydrofolate reductase and cardiovascular disease in Canadian Inuit
-
Hegele RA, Tully C, Young TK, Connelly PW. V677 mutation of methylene-tetrahydrofolate reductase and cardiovascular disease in Canadian Inuit. Lancet 1997;349:1221-2.
-
(1997)
Lancet
, vol.349
, pp. 1221-1222
-
-
Hegele, R.A.1
Tully, C.2
Young, T.K.3
Connelly, P.W.4
-
28
-
-
0027162816
-
Hepatic lipase deficiency: Clinical, biochemical and molecular genetic characteristics
-
Hegele RA, Little JA, Vezina C, Maguire G, Tu L, Wolever TMS, Jenkins DJA, Connelly PW. Hepatic lipase deficiency: clinical, biochemical and molecular genetic characteristics. Arterioscler Thromb Vasc Biol 1993;13:720-8.
-
(1993)
Arterioscler Thromb Vasc Biol
, vol.13
, pp. 720-728
-
-
Hegele, R.A.1
Little, J.A.2
Vezina, C.3
Maguire, G.4
Tu, L.5
Wolever, T.M.S.6
Jenkins, D.J.A.7
Connelly, P.W.8
-
29
-
-
17344368547
-
Elevated low density lipoprotein triglyceride concentrations in subjects heterozygous for hepatic lipase S267F variant
-
Hegele RA, Breckenridge WC, Cox DW, Maguire GF, Little JA, Connelly PW. Elevated low density lipoprotein triglyceride concentrations in subjects heterozygous for hepatic lipase S267F variant. Arterioscler Thromb Vasc Biol 1998;18:1212-6.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 1212-1216
-
-
Hegele, R.A.1
Breckenridge, W.C.2
Cox, D.W.3
Maguire, G.F.4
Little, J.A.5
Connelly, P.W.6
-
30
-
-
15844418442
-
A compound heterozygote for hepatic lipase gene mutations Leu334- > Phe and Thr383- > Met: Correlation between hepatic lipase activity and phenotypic expression
-
Knudsen P, Antikainen M, Ehnholm S, Uusi-Oukari M, Tenkanen H, Lahdenpera S, Kahri J, Tilly-Kiesi M, Bensadoun A, Taskinen MR, Ehnholm C. A compound heterozygote for hepatic lipase gene mutations Leu334- > Phe and Thr383- > Met: correlation between hepatic lipase activity and phenotypic expression. J Lipid Res 1996;37:825-34.
-
(1996)
J Lipid Res
, vol.37
, pp. 825-834
-
-
Knudsen, P.1
Antikainen, M.2
Ehnholm, S.3
Uusi-Oukari, M.4
Tenkanen, H.5
Lahdenpera, S.6
Kahri, J.7
Tilly-Kiesi, M.8
Bensadoun, A.9
Taskinen, M.R.10
Ehnholm, C.11
-
31
-
-
0031052632
-
Heterozygous hepatic lipase deficiency due to two missense mutations R186H and L334F in the HL gene
-
Knudsen P, Antikainen M, Uusi-Oukari M, Ehnholm S, Lahdenpera S, Bensadoun A, Funke H, Wiesbusch H, Assmann G, Taskinen MR, Ehnholm C. Heterozygous hepatic lipase deficiency due to two missense mutations R186H and L334F in the HL gene. Atherosclerosis 1997;128:165-74.
-
(1997)
Atherosclerosis
, vol.128
, pp. 165-174
-
-
Knudsen, P.1
Antikainen, M.2
Uusi-Oukari, M.3
Ehnholm, S.4
Lahdenpera, S.5
Bensadoun, A.6
Funke, H.7
Wiesbusch, H.8
Assmann, G.9
Taskinen, M.R.10
Ehnholm, C.11
-
32
-
-
0029657764
-
A novel A- > G mutation of intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency
-
Brand K, Dugi KA, Brunzell JD, Nevin DN, Santamarina-Fojo S. A novel A- > G mutation of intron I of the hepatic lipase gene leads to alternative splicing resulting in enzyme deficiency. J Lipid Res 1996;37:1213-23.
-
(1996)
J Lipid Res
, vol.37
, pp. 1213-1223
-
-
Brand, K.1
Dugi, K.A.2
Brunzell, J.D.3
Nevin, D.N.4
Santamarina-Fojo, S.5
-
33
-
-
0023234103
-
Lack of sex differences in high density lipoproteins in Pima Indians. Studies of obesity, lipase activities, and steroid hormones
-
Howard BV, Pan XR, Harper I, Kuusi T, Taskinen MR. Lack of sex differences in high density lipoproteins in Pima Indians. Studies of obesity, lipase activities, and steroid hormones. Artherosclerosis 1987;7:292-300.
-
(1987)
Artherosclerosis
, vol.7
, pp. 292-300
-
-
Howard, B.V.1
Pan, X.R.2
Harper, I.3
Kuusi, T.4
Taskinen, M.R.5
-
34
-
-
0019967053
-
Characterization of lipase activities in obese Pima indians. Decreases with weight reduction
-
Reitman JS, Kosmakos FC, Howard BV, Taskinen MR, Kuusi T, Nikkila EA. Characterization of lipase activities in obese Pima indians. Decreases with weight reduction. J Clin Invest 1982;70:791-7.
-
(1982)
J Clin Invest
, vol.70
, pp. 791-797
-
-
Reitman, J.S.1
Kosmakos, F.C.2
Howard, B.V.3
Taskinen, M.R.4
Kuusi, T.5
Nikkila, E.A.6
-
35
-
-
0031774386
-
Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol
-
Zambon A, Deeb SS, Hokanson JE, Brown BG, Brunzell JD. Common variants in the promoter of the hepatic lipase gene are associated with lower levels of hepatic lipase activity, buoyant LDL, and higher HDL2 cholesterol. Arterioscler Thromb Vasc Biol 1998;18:1723-9.
-
(1998)
Arterioscler Thromb Vasc Biol
, vol.18
, pp. 1723-1729
-
-
Zambon, A.1
Deeb, S.S.2
Hokanson, J.E.3
Brown, B.G.4
Brunzell, J.D.5
-
36
-
-
0031947301
-
Body mass index and hepatic lipase gene (LIPC) polymorphism jointly influence postheparin plasma hepatic lipase activity
-
Nie L, Wang J, Clark LT, Tang A, Vega GL, Grundy SM, Cohen JC. Body mass index and hepatic lipase gene (LIPC) polymorphism jointly influence postheparin plasma hepatic lipase activity. J Lipid Res 1998;39:1127-30.
-
(1998)
J Lipid Res
, vol.39
, pp. 1127-1130
-
-
Nie, L.1
Wang, J.2
Clark, L.T.3
Tang, A.4
Vega, G.L.5
Grundy, S.M.6
Cohen, J.C.7
|