Taq1B CETP polymorphism, plasma CETP, lipoproteins, apolipoproteins and sex differences in a Jewish population sample characterized by low HDL- cholesterol

Atherosclerosis

Volumn 151, Issue 2, 2000, Pages 509-518

  Kark, J D ^a   Sinnreich, R ^a   Leitersdorf, E ^a   Friedlander, Y ^a   Shpitzen, S ^a   Luc, G ^b  

^a HADASSAH HEBREW UNIVERSITY MEDICAL CENTER   (Israel)

^b INSTITUT PASTEUR DE LILLE   (France)

Author keywords

Apolipoproteins; CETP; Genetic polymorphisms; HDL cholesterol; Jews; LDL cholesterol; Sex differences; Taq1B

Indexed keywords

APOLIPOPROTEIN; CHOLESTEROL; CHOLESTEROL ESTER TRANSFER PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPID; LIPOPROTEIN; TAQ POLYMERASE;

ADULT; ALLELE; ARTICLE; CHOLESTEROL BLOOD LEVEL; FEMALE; GENE FREQUENCY; GENETIC POLYMORPHISM; HEALTH BEHAVIOR; HUMAN; ISCHEMIC HEART DISEASE; JEW; LIPID BLOOD LEVEL; LIPOPROTEIN BLOOD LEVEL; MALE; PRIORITY JOURNAL; SEX DIFFERENCE;

ALLELES; APOLIPOPROTEINS; CARRIER PROTEINS; CHOLESTEROL ESTER TRANSFER PROTEINS; CHOLESTEROL, HDL; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; FEMALE; GENE FREQUENCY; GLYCOPROTEINS; HUMANS; JEWS; LIPOPROTEINS; MALE; POLYMORPHISM, GENETIC; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; SEX CHARACTERISTICS; SMOKING; TRIGLYCERIDES;

EID: 0033862329     PISSN: 00219150     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0021-9150(99)00408-6     Document Type: Article

References (54)

1. Eisenberg S., Heiss G., Friedlander Y. et al. Comparison of plasma lipids, lipoproteins, and dyslipoproteinemia in Israel and the United States. Atherosclerosis. 59:1986;63-74.
2. Bobak M., Hense H.W., Kark J.D. et al. Explaining cardiovascular disease rate differences: risk factors in Czech, Bavarian and Israeli men. Int. J. Epidemiol. 28:1999;437-444.
3. Miller G.J., Miller N.E. Plasma high density lipoprotein cholesterol concentration in development of ischaemic heart disease. Lancet. 1:1975;16-19.
4. Gordon D.J., Rifkind B.M. High-density lipoprotein: the clinical implications of recent studies. New Engl. J. Med. 321:1989;1311-1316.
5. Brunner D., Loeb K. Serum cholesterol, electrophoretic lipid pattern, diet and coronary heart disease: a study in coronary patients and in healthy men of different origin and occupation in Israel. Ann. Intern. Med. 49:1958;732-750.
6. Brunner D., Altman S., Loebl K., Schwartz S. Cholesterol percentages in coronary patients with and without increased total serum cholesterol levels and in healthy controls. J. Atheroscler. Res. 2:1962;424-437.
7. Goldbourt U., Medalie J.H. High density lipoprotein cholesterol and coronary heart disease incidence - The Israeli Ischemic Heart Disease Study. Am. J. Epidemiol. 109:1979;296-308.
8. Goldbourt U., Kark J.D. The epidemiology of coronary heart disease in the ethnically and culturally diverse population of Israel. Isr. J. Med. Sci. 18:1982;1077-1097.
9. Friedlander Y., Lev-Merom D., Kark J.D. A comparison of different matching designs in case-control studies: an empirical example using continuous exposures, continuous confounders and incidence of myocardial infarction. Stat. Med. 12:1993;993-1004.
10. Kaufmann N.A., Dennis B.H., Heiss G., Friedlander Y., Kark J.D., Stein Y. Comparison of nutrient intake of selected populations in the United States and Israel: The Lipid Research Clinics Prevalence Study. Am. J. Clin. Nutr. 43:1986;604-620.
11. World Health Organization. Highlights on Health in Israel. WHO Regional Office for Europe, Copenhagen 1996.
12. Bucher K.D., Friedlander Y., Kaplan E.B. et al. Biological and cultural sources of familial resemblance in plasma lipids: a comparison between North America and Israel - the Lipid Research Clinics Program. Genet. Epidemiol. 5:1988;17-33.
13. Friedlander Y., Kark J.D., Stein Y. Complex segregation analysis of low levels of plasma high-density lipoprotein cholesterol in a sample of nuclear families in Jerusalem. Genet. Epidemiol. 3:1986;285-297.
14. Pocovi M., Cenarro A., Civeira F. et al. B-glucocerebrosidase gene locus as a link for Gaucher's disease and familial hypo-a-lipoproteinaemia. Lancet. 352:1998;1919-1923.
15. Zimran A., Gelbart T., Westwood B., Grabowski G.A., Beutler E. High frequency of the Gaucher disease mutation at nucleotide 1226 among Ashkenazi Jews. Am. J. Hum. Gen. 49:1991;855-859.
16. Beutler E., Nguyen N.J., Henneberger M.W. et al. Gaucher disease: gene frequencies in the Ashkenazi Jewish population. Am. J. Hum. Genet. 52:1993;85-88.
17. Tall A.R. Plasma high density lipoproteins: metabolism and relation to atherogenesis. J. Clin. Invest. 86:1990;379-384.
18. Tall A.R. Plasma cholesterol ester transfer protein. J. Lipid Res. 34:1993;1255-1274.
19. Bruce C., Tall A.R. Cholesterol ester transfer proteins, reverse cholesterol transport, and atherosclerosis. Curr. Opin. Lipidol. 6:1995;306-311.
20. Bhatnagar D., Durrington P.N., Channon K.M., Prais H., Mackness M.I. Increased transfer of cholesterol esters from high density lipoproteins to low density and very low density lipoproteins in patients with angiographic evidence of coronary heart disease. Atherosclerosis. 98:1993;25-32.
21. Tato F., Vega G.L., Grundy S.M. Bimodal distribution of cholesterol ester transfer protein activities in normotriglyceridemic men with low HDL cholesterol concentrations. Arterioscler. Thromb. Vasc. Biol. 15:1995;446-451.
22. Fumeron F., Betoulle D., Luc G. et al. Alcohol intake modulates the effect of a polymorphism of the cholesterol ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction. J. Clin. Invest. 96:1995;1664-1671.
23. Kuivenhoven J.A., Jukema J.W., Zwinderman A.H. et al. The role of a common variant of the cholesterol ester transfer protein gene in the progression of coronary atherosclerosis. New Engl. J. Med. 338:1998;86-93.
24. Zhong S., Sharp D.S., Grove J.S. et al. Increased coronary heart disease in Japanese-American men with mutation in the cholesterol ester transfer protein despite increased HDL levels. J. Clin. Invest. 97:1996;2917-2923.
25. Freeman D.J., Packard C.J., Sherperd J., Gaffney D. Polymorphisms in the gene coding for cholesterol ester transfer protein are related to plasma high-density lipoprotein cholesterol and transfer protein activity. Clin. Sci. 79:1990;575-581.
26. Hannuksela M.L., Liinamaa M.J., Kesaniemi Y.A., Savolainen M.J. Relation of polymorphisms in the cholesterol ester transfer protein gene to tranfer protein activity and plasma lipoprotein levels in alcohol drinkers. Atherosclerosis. 110:1994;35-44.
27. Kuivenhoven J.A., de Knijff P., Boer J.M.A. et al. Heterogeneity at the CETP locus gene. Influence on plasma CETP concentrations and HDL cholesterol levels. Arterioscler. Thromb. Vasc. Biol. 17:1997;560-568.
28. McPherson R., Grundy S., Guerra R., Cohen J.C. Allelic variation in the gene encoding the cholesterol ester transfer protein is associated with variation in the plasma concentrations of cholesterol ester transfer protein. J. Lipid Res. 37:1996;1743-1748.
29. Foger B., Ritsch A., Doblinger A., Wessels H., Patsch J.R. Relationship of plasma cholesterol ester transfer protein to HDL cholesterol. Arterioscler. Thromb. Vasc. Biol. 16:1996;1430-1436.
30. Mann C.J., Yen F.T., Grant A.M., Bihain B.E. Mechanism of plasma cholesterol ester transfer in hypertriglyceridemia. J. Clin. Invest. 88:1991;2059-2066.
31. Kondo I., Berg K., Drayna D., Lawn R. DNA polymorphism at the locus for human cholesterol ester transfer protein (CETP) is associated with high density lipoprotein cholesterol and apolipoprotein levels. Clin. Genet. 35:1989;49-56.
32. Mendis S., Sherperd J., Packard C.J., Gaffney D. Genetic variation in the cholesterol ester transfer protein and apolipoprotein A-1 genes and its relation to coronary heart disease in a Sri Lankan population. Atherosclerosis. 83:1990;21-27.
33. Freeman D.J., Griffin B.A., Holmes A.P. et al. Regulation of plasma HDL cholesterol and subfraction distribution by genetic and environmental factors: associations between the Taq1 B RFLP in the CETP gene and smoking and obesity. Arterioscler. Thromb. 14:1994;336-344.
34. Mitchell R.J., Earl L., Williams J., Bisucci T., Gasiamis H. Polymorphisms of the gene coding for the cholesterol ester transfer protein and plasma lipid levels in Italian and Greek migrants to Australia. Hum. Biol. 66:1994;13-25.
35. Bu X., Warden C.H., Xia Y.R. et al. Linkage analysis of the genetic determinants of high density lipoprotein concentrations and composition: evidence for involvement of the apolipoprotein A-II and cholesterol ester transfer protein. Hum. Genet. 93:1994;639-648.
36. Kauma H., Savolainen M.J., Heikkila R. et al. Sex difference in the regulation of plasma high density lipoprotein cholesterol by genetic and environmental factors. Hum. Genet. 97:1996;156-162.
37. Funke H., Wiebusch H., Fuer L., Muntoni S., Schulte H., Assmann G. Identification of mutations in the cholesterol ester transfer proteins in Europeans with elevated high density lipoprotein cholesterol. Circulation. 90(2):1994;241. Abstract.
38. Cohen J.C., Wang Z., Grundy S.M., Stoesz M.R., Guerra R. Variation at the hepatic lipase and apolipoprotein AI/CIII/AIV loci is a major cause of genetically determined variation in plasma HDL cholesterol levels. J. Clin. Invest. 94:1994;2377-2384.
39. Tenkanen H., Koskinen P., Kontula K. et al. Polymorphisms of the gene encoding for cholesterol ester transfer protein and serum lipoprotein levels in subjects with and without coronary heart disease. Hum. Genet. 87:1991;574-578.
40. Slater P.E., Friedlander Y., Baras M. et al. The Jerusalem Lipid Research Clinic: sampling, response and selected methodological issues. Isr. J. Med. Sci. 18:1982;1106-1112.
41. Kinoshita M., Teramoto T., Shimazu N. et al. CETP is a determinant of serum LDL-cholesterol but not HDL-cholesterol in healthy Japanese. Atherosclerosis. 120:1996;75-82.
42. McPherson R., Mann C.J., Tall A.R. et al. Plasma concentrations of cholesterol ester transfer protein in hyperproteinemia. Relation to cholesterol ester transfer protein activity and other lipoprotein variables. Arterioscler. Thromb. 11:1991;797-804.
43. Mezdour H., Kora I., Parra H.J., Tartar A., Marcel Y.A., Fruchard J.C. Two-site enzyme immunoassay of cholesterol ester transfer protein with monoclonal and polyclonal antibodies. Clin. Chem. 40:1994;593-597.
44. MacLean J., Morton N.E., Elston R.C., Yee S. Skewness in commingled distributions. Biometrics. 32:1976;695-699.
45. Friedlander Y., Kark J.D., Cohen T., Eisenberg S., Stein Y. Admixture analysis of high density lipoprotein cholesterol distribution in a Jerusalem population sample. Clin. Genet. 24:1983;117-127.
46. Kardinaal A.F.M., Aro A., Kark J.D. et al. Association between B-carotene and acute myocardial infarction depends on polyunsaturated fatty acid status. The EURAMIC study. Arterioscler. Thromb. Vasc. Biol. 15:1995;726-732.
47. Kessling A., Ouellette S., Bouffard O. et al. Patterns of association between genetic variability in apolipoprotein (apo)B, apo AI-CIII-AIV, and cholesterol ester transfer protein gene regions and quantitative variation in lipid and lipoprotein traits: influence of gender and exogenous hormones. Am. J. Hum. Genet. 50:1992;92-106.
48. Marcel Y.L., McPherson R., Hogue M. et al. Distribution and concentration of cholesterol ester transfer protein in plasma of normolipidemic subjects. J. Clin. Invest. 85:1990;10-17.
49. Moulin P., Cheung M.C., Austin A.A. et al. Gender effect on the distribution of the cholesterol ester transfer protein in apolipoprotein A-1-defined lipoprotein subpopulations. J. Lipid Res. 35:1994;793-802.
50. Roma P., Gregg R.E., Meng M.S. et al. In vivo metabolism of a mutant form of apolipoprotein A-1, apo A-1 Milano associated with familial hypoalphalipoproteinemia. J. Clin. Invest. 91:1993;1445-1452.
51. Betteridge D.J., Kahn M. Genetic influence on HDL cholesterol. Lancet. 351:1998;1903-1904.
52. Gylling H., Vega G.L., Grundy S.M. Physiologic mechanisms for reduced apolipoprotein A-1 concentrations associated with low levels of high density lipoprotein cholesterol in patients with normal plasma lipids. J. Lipid Res. 33:1992;1527-1539.
53. Brinton E.A., Eisenberg S., Breslow J.L. Human HDL cholesterol levels are determined by apo A-1 fractional catabolic rate, which correlates inversely with estimates of HDL particle size. Effects of gender, hepatic and lipoprotein lipases, triglyceride and insulin levels, and body fat distribution. Arterioscler. Thromb. 14:1994;707-720.
54. Bersot TP, Vega GL, Grundy SM, et al. Elevated hepatic lipase activity and low levels of high density lipoprotein in a normotriglyceridemic, nonodese Turkish population. J Lipid Res 1999;40:432-8.