Promoter identification of CIKS, a novel NF-κB activating gene, and regulation of its expression

Gene

Volumn 307, Issue 1-2, 2003, Pages 99-109

  Pacifico, Francesco ^a   Barone, Ciro ^a   Mellone, Stefano ^a   Di Jeso, Bruno ^c   Consiglio, Eduardo ^a   Formisano, Silvestro ^a   Vito, Pasquale ^b   Leonardi, Antonio ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b Grande Ospedale Metropolitano   (Italy)

^c UNIVERSITY OF SALENTO   (Italy)

Author keywords

NF B; Promoter; Transcriptional regulation

Indexed keywords

CYTOKINE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; LUCIFERASE; MESSENGER RNA; NUCLEAR PROTEIN; PROTEIN; PROTEIN CIKS; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BINDING SITE; CELL LINE; CONTROLLED STUDY; DNA FLANKING REGION; ENZYME ACTIVITY; EPITHELIUM CELL; GENE ACTIVITY; GENE CONTROL; GENE EXPRESSION; GENE MAPPING; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; NONHUMAN; NORTHERN BLOTTING; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; TRANSCRIPTION INITIATION; UPREGULATION; WESTERN BLOTTING;

EID: 0347928836     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(03)00448-7     Document Type: Article

References (26)

1. Brown K., Gerstberger S., Carlson L., Franzoso G., Siebenlist U. Control of I kappa B-alpha proteolysis by site-specific, signal-induced phosphorylation. Science. 267:1995;1485-1488.
2. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
3. Eckner R., Yao T.P., Oldread E., Livingston D.M. Interaction and functional collaboration of p300/CBP and bHLH proteins in muscle and B-cell differentiation. Genes Dev. 10:1996;2478-2490.
4. Ghosh S., May M.J., Kopp E.B. NF-κB and Rel proteins: evolutionarily conserved mediators of immune responses. Annu. Rev. Immunol. 16:1998;225-260.
5. Innis M.A., Gelfand D.H., Sninsky J.J., White T.J. PCR Protocols, A Guide to Methods and Applications. 1990;Academic Press, New York.
6. Javahery R., Khachi A., Lo K., Zenzie-Gregory B., Smale S.T. DNA sequence requirements for transcriptional initiator activity in mammalian cells. Mol. Cell. Biol. 14:1994;116-127.
7. Kablar B. Different regulatory elements within the MyoD promoter control its expression in the brain and inhibit its functional consequences in neurogenesis. Tissue Cell. 34:2002;164.
8. Karin M. How NF-κB is activated: the role of the IκB kinase (IKK) complex. Oncogene. 18:1999;6867-6874.
9. Karin M., Ben-Neriah Y. Phosphorylation meets ubiquitination: control of NF κB activity. Annu. Rev. Immunol. 18:2000;621-663.
10. Kirstetter P., Thomas M., Dierich A., Kastner P., Chan S. Ikaros is critical for B cell differentiation and function. Eur. J. Immunol. 32:2002;720-730.
11. Koopman P. The molecular biology of SRY and its role in sex determination in mammals. Reprod. Fertil. Dev. 7:1995;713-722.
12. Leonardi A., Chariot A., Claudio E., Cunningham K., Siebenlist U. CIKS, a connection to IκB kinase and stress-activated protein kinase. Proc. Natl. Acad. Sci. USA. 97:2000;10494-10499.
13. Li X., Commane M., Nie H., Hua X., Chatterjee-Kishore M., Wald D., Haag M., Stark G.R. Act1, an NF-κB-activating protein. Proc. Natl. Acad. Sci. USA. 97:2000;10489-10493.
14. Lints T.J., Parsons L.M., Hartley L., Lyons I., Harvey R.P. Nkx-2.5: a novel murine homeobox gene expressed in early heart progenitor cells and their myogenic descendants. Development. 119:1993;419-431.
15. Maniatis T., Fritsch E.F., Sambrook J. Molecular Cloning: A Laboratory Manual. 1989;Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
16. Morelli C., Magnanini C., Mungall A.J., Negrini M., Barbanti-Brodano G. Cloning and characterization of two overlapping genes in a subregion at 6q21 involved in replicative senescence and schizophrenia. Gene. 252:2000;217-225.
17. Osborne B.A. Transcriptional control of T cell development. Curr. Opin. Immunol. 12:2000;301-306.
18. Pahl H.L. Activators and target genes of Rel/NF-kappaB transcription factors. Oncogene. 18:1999;6853-6866.
19. Qian Y., Zhao Z., Jiang Z., Li X. Role of NF-κB activator Act1 in CD40-mediated signaling in epithelial cells. Proc. Natl. Acad. Sci. USA. 99:2002;9386-9391.
20. Rothwarf D.M., Zandi E., Natoli G., Karin M. IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex. Nature. 395:1998;297-300.
21. Smits P., Li P., Mandel J., Zhang Z., Deng J.M., Behringer R.R., de Croumbrugghe B., Lefebvre V. The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev. Cell. 1:2001;277-290.
22. Tak P.P., Firestein G.S. NF-κB: a key role in inflammatory diseases. J. Clin. Invest. 107:2001;7-11.
23. Verma I.M., Stevenson J.K., Schwarz E.M., Van Antwerp D., Miyamoto S. Rel/NF kappa B/I kappa B family: intimate tales of association and dissociation. Genes Dev. 9:1995;2723-2735.
24. Xia Y.F., Li Y.D., Li X., Geng J.G. Identification of alternatively spliced Act1 and implications for its roles in oncogenesis. Biochem. Biophys. Res. Commun. 296:2002;406-412.
25. Yamaoka S., Courtois G., Bessia C., Whiteside S.T., Weil R., Agou F., Kirk H.E., Kay R.J., Israel A. Complementation cloning of NEMO, a component of the IkappaB kinase complex essential for NF-kappaB activation. Cell. 93:1998;1231-1240.
26. Yun K., Wold B. Skeletal muscle determination and differentiation: story of a core regulatory network and its context. Curr. Opin. Cell. Biol. 8:1996;877-889.