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Volumn 18, Issue 6, 1997, Pages 641-649

Nimodipine ameliorates impaired eyeblink classical conditioning in older rabbits in the long-delay paradigm

Author keywords

Alzheimer's disease; Calcium channel blocker; Classical conditioning; Hippocampus; Learning; Nictitating membrane; Nimodipine aging; Rabbit

Indexed keywords

NIMODIPINE; SCOPOLAMINE;

EID: 0031440589     PISSN: 01974580     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0197-4580(97)00159-0     Document Type: Article
Times cited : (17)

References (70)
  • 1
    • 0028596018 scopus 로고
    • Cerebellar and brainstem circuits involved in classical eyeblink conditioning
    • Anderson B. J., Steinmetz J. E. Cerebellar and brainstem circuits involved in classical eyeblink conditioning. Rev. Neurosci. 5:1994;251-273.
    • (1994) Rev. Neurosci. , vol.5 , pp. 251-273
    • Anderson, B.J.1    Steinmetz, J.E.2
  • 2
    • 0029593611 scopus 로고
    • The effects of scopolamine, lorazepam, and glycopyrrolate on classical conditioning of the human eyeblink response
    • Bahro M., Schreurs B. G., Sunderland T., Molchan S. E. The effects of scopolamine, lorazepam, and glycopyrrolate on classical conditioning of the human eyeblink response. Psychopharmacol. 122:1995;395-400.
    • (1995) Psychopharmacol. , vol.122 , pp. 395-400
    • Bahro, M.1    Schreurs, B.G.2    Sunderland, T.3    Molchan, S.E.4
  • 3
    • 0028107456 scopus 로고
    • Normal aging: Regionally specific changes in hippocampal synaptic transmission
    • Barnes C. A. Normal aging Regionally specific changes in hippocampal synaptic transmission . Trends Neurosci. 17:1994;13-18.
    • (1994) Trends Neurosci. , vol.17 , pp. 13-18
    • Barnes, C.A.1
  • 4
    • 0021321761 scopus 로고
    • Long-term potentiation of hippocampal synaptic transmission affects rate of behavioral learning
    • Berger T. W. Long-term potentiation of hippocampal synaptic transmission affects rate of behavioral learning. Science. 224:1984;627-630.
    • (1984) Science , vol.224 , pp. 627-630
    • Berger, T.W.1
  • 5
    • 0017276692 scopus 로고
    • Neuronal substrate of classical conditioning in the hippocampus
    • Berger T. W., Alger B. E., Thompson R. F. Neuronal substrate of classical conditioning in the hippocampus. Science. 192:1976;483-485.
    • (1976) Science , vol.192 , pp. 483-485
    • Berger, T.W.1    Alger, B.E.2    Thompson, R.F.3
  • 6
    • 0000196748 scopus 로고
    • Role of the hippocampus in classical conditioning of aversive and appetitive behaviors
    • R.L. Isaacson, Pribram K.H. New York: Plenum
    • Berger T. W., Berry S. D., Thompson R. F. Role of the hippocampus in classical conditioning of aversive and appetitive behaviors. Isaacson R. L., Pribram K. H. The Hippocampus. vol. 4:1986;203-239 Plenum, New York.
    • (1986) The Hippocampus , vol.4 , pp. 203-239
    • Berger, T.W.1    Berry, S.D.2    Thompson, R.F.3
  • 7
    • 0020623546 scopus 로고
    • Hippocampectomy selectively disrupts discrimination reversal conditioning of the rabbit nictitating membrane response
    • Berger T. W., Orr W. B. Hippocampectomy selectively disrupts discrimination reversal conditioning of the rabbit nictitating membrane response. Behav. Brain Res. 8:1983;49-68.
    • (1983) Behav. Brain Res. , vol.8 , pp. 49-68
    • Berger, T.W.1    Orr, W.B.2
  • 8
    • 0021046701 scopus 로고
    • Single unit analysis of different hippocampal cell types during classical conditioning of the rabbit NM response
    • Berger T. W., Rinaldi P., Weisz D. J., Thompson R. F. Single unit analysis of different hippocampal cell types during classical conditioning of the rabbit NM response. J. Neurophysiol. 59:1983;1197-1219.
    • (1983) J. Neurophysiol. , vol.59 , pp. 1197-1219
    • Berger, T.W.1    Rinaldi, P.2    Weisz, D.J.3    Thompson, R.F.4
  • 9
    • 0006073716 scopus 로고
    • Identification of pyramidal cells as the critical elements in hippocampal neuronal plasticity during learning
    • Berger, T. W.; Thompson, R. F. Identification of pyramidal cells as the critical elements in hippocampal neuronal plasticity during learning. Proc. Natl. Acad. Sci. USA 75:1572-57; 1978.
    • (1978) Proc. Natl. Acad. Sci. USA , vol.75 , pp. 1572-1657
    • Berger, T.W.1    Thompson, R.F.2
  • 10
    • 0017847951 scopus 로고
    • Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response. I. The hippocampus
    • Berger T. W., Thompson R. F. Neuronal plasticity in the limbic system during classical conditioning of the rabbit nictitating membrane response. I. The hippocampus. Brain Res. 145:1978;323-346.
    • (1978) Brain Res. , vol.145 , pp. 323-346
    • Berger, T.W.1    Thompson, R.F.2
  • 11
    • 0026473990 scopus 로고
    • Hippocampectomy disrupts the topography of the rat eyeblink response during acquisition and extinction of classical conditioning
    • Christiansen B. A., Schmajuk N. A. Hippocampectomy disrupts the topography of the rat eyeblink response during acquisition and extinction of classical conditioning. Brain Res. 595:1992;206-214.
    • (1992) Brain Res. , vol.595 , pp. 206-214
    • Christiansen, B.A.1    Schmajuk, N.A.2
  • 12
    • 0027157936 scopus 로고
    • Delay classical conditioning in young and older rabbits: Acquisition and retention at 12 and 18 months
    • Coffin J. M., Woodruff-Pak D. S. Delay classical conditioning in young and older rabbits Acquisition and retention at 12 and 18 months . Behav. Neurosci. 107:1993;63-71.
    • (1993) Behav. Neurosci. , vol.107 , pp. 63-71
    • Coffin, J.M.1    Woodruff-Pak, D.S.2
  • 13
    • 0024561984 scopus 로고
    • Classical conditioning reduces amplitude and duration of calcium-dependent after hyperpolarization in rabbit hippocampal pyramidal cells
    • Coulter D. A., Lo Turco J. J., Kubota M., Disterhoft J. F., Moore J. F., Alkon D. L. Classical conditioning reduces amplitude and duration of calcium-dependent after hyperpolarization in rabbit hippocampal pyramidal cells. J. Neurophysiol. 61:1989;971-981.
    • (1989) J. Neurophysiol. , vol.61 , pp. 971-981
    • Coulter, D.A.1    Lo Turco, J.J.2    Kubota, M.3    Disterhoft, J.F.4    Moore, J.F.5    Alkon, D.L.6
  • 15
    • 0025857217 scopus 로고
    • Classical conditioning after temporal lobe lesions in man: Impairment in conditional discrimination
    • Daum I., Channon S., Polkey C. E., Gray J. A. Classical conditioning after temporal lobe lesions in man Impairment in conditional discrimination . Behav. Neurosci. 105:1991;396-408.
    • (1991) Behav. Neurosci. , vol.105 , pp. 396-408
    • Daum, I.1    Channon, S.2    Polkey, C.E.3    Gray, J.A.4
  • 16
    • 0024514210 scopus 로고
    • Nimodipine facilitates associative learning in aging rabbits
    • Deyo R. A., Straube K. T., Disterhoft J. F. Nimodipine facilitates associative learning in aging rabbits. Science. 243:1989;809-811.
    • (1989) Science , vol.243 , pp. 809-811
    • Deyo, R.A.1    Straube, K.T.2    Disterhoft, J.F.3
  • 17
    • 0022551160 scopus 로고
    • Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro
    • Disterhoft J. F., Coulter D. A., Alkon D. L. Conditioning-specific membrane changes of rabbit hippocampal neurons measured in vitro. Proc. Natl. Acad. Sci. USA. 83:1986;2733-2737.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 2733-2737
    • Disterhoft, J.F.1    Coulter, D.A.2    Alkon, D.L.3
  • 19
    • 0001827521 scopus 로고
    • Cellular mechanisms of associative learning in the hippocampus
    • J. Delacour. Singapore: World Scientific
    • Disterhoft J. F., Thompson L. T., Moyer J. R. Cellular mechanisms of associative learning in the hippocampus. Delacour J. The Memory System of the Brain. 1994;431-491 World Scientific, Singapore.
    • (1994) The Memory System of the Brain , pp. 431-491
    • Disterhoft, J.F.1    Thompson, L.T.2    Moyer, J.R.3
  • 21
    • 0021995409 scopus 로고
    • Age related disruption of trace but not delay classical conditioning of the rabbit's nictitating membrane response
    • Graves C. A., Solomon P. R. Age related disruption of trace but not delay classical conditioning of the rabbit's nictitating membrane response. Behav. Neurosci. 99:1985;88-96.
    • (1985) Behav. Neurosci. , vol.99 , pp. 88-96
    • Graves, C.A.1    Solomon, P.R.2
  • 22
    • 0020633339 scopus 로고
    • Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response
    • Harvey J. A., Gormezano I., Cool-Hauser V. A. Effects of scopolamine and methylscopolamine on classical conditioning of the rabbit nictitating membrane response. J. Pharmacol. Exp. Ther. 225:1983;42-49.
    • (1983) J. Pharmacol. Exp. Ther. , vol.225 , pp. 42-49
    • Harvey, J.A.1    Gormezano, I.2    Cool-Hauser, V.A.3
  • 23
    • 0023127354 scopus 로고
    • Hippocampal lesions and trace conditioning in the rabbit
    • James G. O., Hardiman M. J., Yeo C. H. Hippocampal lesions and trace conditioning in the rabbit. Behav. Brain Res. 23:1987;109-116.
    • (1987) Behav. Brain Res. , vol.23 , pp. 109-116
    • James, G.O.1    Hardiman, M.J.2    Yeo, C.H.3
  • 24
    • 0002502956 scopus 로고
    • Toward theories of brain aging
    • D.W. Kay, & G.D. Burrows. New York: Elsevier
    • Khachaturian Z. S. Toward theories of brain aging. Kay D. W., Burrows G. D. Handbook of Studies in Psychiatry and Old Age. 1984;7-30 Elsevier, New York.
    • (1984) Handbook of Studies in Psychiatry and Old Age , pp. 7-30
    • Khachaturian, Z.S.1
  • 25
    • 84950375413 scopus 로고
    • The role of calcium regulation in brain aging: Reexamination of a hypothesis
    • Khachaturian Z. S. The role of calcium regulation in brain aging Reexamination of a hypothesis . Aging. 1:1989;17-34.
    • (1989) Aging , vol.1 , pp. 17-34
    • Khachaturian, Z.S.1
  • 26
    • 0028305203 scopus 로고
    • Relation of nimodipine dose and serum concentration to learning enhancement in aging rabbits
    • Kowalska M., Disterhoft J. F. Relation of nimodipine dose and serum concentration to learning enhancement in aging rabbits. Exp. Neurol. 127:1994;159-166.
    • (1994) Exp. Neurol. , vol.127 , pp. 159-166
    • Kowalska, M.1    Disterhoft, J.F.2
  • 28
    • 0021958255 scopus 로고
    • Effect of kainic acid lesions of the cerebellar interpositus nucleus on eyelid conditioning in the rabbit
    • Lavond D. G., Hembree T. L., Thompson R. F. Effect of kainic acid lesions of the cerebellar interpositus nucleus on eyelid conditioning in the rabbit. Brain Res. 326:1985;179-182.
    • (1985) Brain Res. , vol.326 , pp. 179-182
    • Lavond, D.G.1    Hembree, T.L.2    Thompson, R.F.3
  • 29
    • 0027344055 scopus 로고
    • Mammalian brain substrates of aversive classical conditioning
    • Lavond D. G., Kim J. J., Thompson R. F. Mammalian brain substrates of aversive classical conditioning. Ann. Rev Psychology. 44:1993;317-342.
    • (1993) Ann. Rev Psychology , vol.44 , pp. 317-342
    • Lavond, D.G.1    Kim, J.J.2    Thompson, R.F.3
  • 30
    • 0023375953 scopus 로고
    • "increased calcium current" hypothesis of brain aging
    • Landfield P. W. "Increased calcium current" hypothesis of brain aging. Neurobiol. Aging. 8:1987;346-354.
    • (1987) Neurobiol. Aging , vol.8 , pp. 346-354
    • Landfield, P.W.1
  • 31
    • 0021645626 scopus 로고
    • 2+-dependent afterhyperpolarization in hippocampal neurons of aged rats
    • 2+-dependent afterhyperpolarization in hippocampal neurons of aged rats. Science. 226:1984;1089-1092.
    • (1984) Science , vol.226 , pp. 1089-1092
    • Landfield, P.W.1    Pitler, T.A.2
  • 32
    • 0022871592 scopus 로고
    • Hippocampal pyramidal cells and aging in the human: A quantitative study of neuronal loss in sectors CA1 to CA4
    • Mani R. B., Lohr J. B., Jeste D. V. Hippocampal pyramidal cells and aging in the human A quantitative study of neuronal loss in sectors CA1 to CA4 . Exp. Neurol. 94:1986;29-40.
    • (1986) Exp. Neurol. , vol.94 , pp. 29-40
    • Mani, R.B.1    Lohr, J.B.2    Jeste, D.V.3
  • 33
    • 0021344334 scopus 로고
    • Cerebellum. Essential involvement in the classically conditioned eyelid response
    • McCormick D. A., Thompson R. F. Cerebellum. Essential involvement in the classically conditioned eyelid response. Science. 223:1984;296-299.
    • (1984) Science , vol.223 , pp. 296-299
    • McCormick, D.A.1    Thompson, R.F.2
  • 34
    • 0021686453 scopus 로고
    • Neuronal responses of the rabbit cerebellum during acquisition and performance of a classically conditioned nictitating membrane- eyelid response
    • McCormick D. A., Thompson R. F. Neuronal responses of the rabbit cerebellum during acquisition and performance of a classically conditioned nictitating membrane- eyelid response. J. Neurosci. 4:1984;2811-2822.
    • (1984) J. Neurosci. , vol.4 , pp. 2811-2822
    • McCormick, D.A.1    Thompson, R.F.2
  • 35
    • 0017145950 scopus 로고
    • Central cholinergic blockage by scopolamine and habituation, classical conditioning, and latent inhibition of rabbit's nictitating membrane response
    • Moore J. W., Goodell N. A., Solomon P. R. Central cholinergic blockage by scopolamine and habituation, classical conditioning, and latent inhibition of rabbit's nictitating membrane response. Physiol. Psychol. 4:1976;395-399.
    • (1976) Physiol. Psychol. , vol.4 , pp. 395-399
    • Moore, J.W.1    Goodell, N.A.2    Solomon, P.R.3
  • 36
    • 0025365108 scopus 로고
    • Hippocampectomy disrupts trace eyeblink conditioning in rabbits
    • Moyer J. R. Jr, Deyo R. A., Disterhoft J. F. Hippocampectomy disrupts trace eyeblink conditioning in rabbits. Behav. Neurosci. 104:1990;243-252.
    • (1990) Behav. Neurosci. , vol.104 , pp. 243-252
    • Moyer J.R., Jr.1    Deyo, R.A.2    Disterhoft, J.F.3
  • 37
    • 0028339014 scopus 로고
    • Increased calcium action potentials in aging rabbit CA1 neurons are reduced by low concentrations of nimodipine
    • Moyer J. R., Disterhoft J. F. Increased calcium action potentials in aging rabbit CA1 neurons are reduced by low concentrations of nimodipine. Hippocampus. 4:1994;11-18.
    • (1994) Hippocampus , vol.4 , pp. 11-18
    • Moyer, J.R.1    Disterhoft, J.F.2
  • 38
    • 0027070788 scopus 로고
    • Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- And concentration-dependent manner
    • Moyer J. R., Thompson L. F., Black, Disterhoft J. F. Nimodipine increases excitability of rabbit CA1 pyramidal neurons in an age- and concentration-dependent manner. J. Neurophysiol. 68:1992;2100-2109.
    • (1992) J. Neurophysiol. , vol.68 , pp. 2100-2109
    • Moyer, J.R.1    Thompson, L.F.2    Black3    Disterhoft, J.F.4
  • 39
    • 0021999406 scopus 로고
    • Differential effects of hippocampectomy on classically conditioned rabbit nictitating membrane response related to interstimulus interval
    • Port R. L., Mikhail A. A., Patterson M. M. Differential effects of hippocampectomy on classically conditioned rabbit nictitating membrane response related to interstimulus interval. Behav. Neurosci. 99:1985;200-208.
    • (1985) Behav. Neurosci. , vol.99 , pp. 200-208
    • Port, R.L.1    Mikhail, A.A.2    Patterson, M.M.3
  • 40
    • 0023025463 scopus 로고
    • Retention and acquisition of classical trace-conditioned responses by rabbits with hippocampal lesions
    • Port R. L., Romano A. G., Steinmetz J. E., Mikhail A. A., Patterson M. M. Retention and acquisition of classical trace-conditioned responses by rabbits with hippocampal lesions. Behav. Neurosci. 100:1986;745-752.
    • (1986) Behav. Neurosci. , vol.100 , pp. 745-752
    • Port, R.L.1    Romano, A.G.2    Steinmetz, J.E.3    Mikhail, A.A.4    Patterson, M.M.5
  • 41
    • 0019833760 scopus 로고
    • Age-related changes in classic (Pavlovian) conditioning in the New Zealand albino rabbit
    • Powell D. A., Buchanan S. L., Hernandez L. L. Age-related changes in classic (Pavlovian) conditioning in the New Zealand albino rabbit. Exp. Aging Res. 7:1981;453-465.
    • (1981) Exp. Aging Res. , vol.7 , pp. 453-465
    • Powell, D.A.1    Buchanan, S.L.2    Hernandez, L.L.3
  • 42
    • 0024441434 scopus 로고
    • Scopolamine disruption of septo-hippocampal activity and classical conditioning
    • Salvatierra A. T., Berry S. D. Scopolamine disruption of septo-hippocampal activity and classical conditioning. Behav. Neurosci. 103:1989;715-721.
    • (1989) Behav. Neurosci. , vol.103 , pp. 715-721
    • Salvatierra, A.T.1    Berry, S.D.2
  • 43
    • 0343352409 scopus 로고
    • Age differences in rabbits in the delay classical conditioning paradigm using 400 and 750 msec CS-US intervals
    • Sasse D. K., Coffin J. M., Woodruff-Pak D. S. Age differences in rabbits in the delay classical conditioning paradigm using 400 and 750 msec CS-US intervals. Soc. Neurosci. Abstr. 17:1991;1140.
    • (1991) Soc. Neurosci. Abstr. , vol.17 , pp. 1140
    • Sasse, D.K.1    Coffin, J.M.2    Woodruff-Pak, D.S.3
  • 44
    • 0345276830 scopus 로고
    • Classical conditioning in young and older rabbits in delay and trace paradigms with a 750 msec CS-US interval
    • Sasse D. C., Woodruff-Pak D. S. Classical conditioning in young and older rabbits in delay and trace paradigms with a 750 msec CS-US interval. Soc. Neurosci. Abstr. 16:1990;841.
    • (1990) Soc. Neurosci. Abstr. , vol.16 , pp. 841
    • Sasse, D.C.1    Woodruff-Pak, D.S.2
  • 45
    • 0002275398 scopus 로고    scopus 로고
    • Structural and functional changes in the aging brain
    • J.E. Birren, & K.W. Schaie. San Diego: Academic Press
    • Scheibel A. B. Structural and functional changes in the aging brain. Birren J. E., Schaie K. W. Handbook of the Psychology of Aging. 4th ed. 1996;105-128 Academic Press, San Diego.
    • (1996) Handbook of the Psychology of Aging 4th Ed. , pp. 105-128
    • Scheibel, A.B.1
  • 46
    • 0015336842 scopus 로고
    • Acquisition and extinction of a classically conditioned response in hippocampectomized rabbits (Oryctologaus cuniculus)
    • Schmaltz L. W., Theios J. Acquisition and extinction of a classically conditioned response in hippocampectomized rabbits (Oryctologaus cuniculus). J. Comp. Physiol. Psychol. 79:1972;328-333.
    • (1972) J. Comp. Physiol. Psychol. , vol.79 , pp. 328-333
    • Schmaltz, L.W.1    Theios, J.2
  • 48
    • 0030006439 scopus 로고    scopus 로고
    • Classical conditioning in aged rabbits: Delay, trace, and long-delay conditioning
    • Solomon P. R., Groccia-Ellison M. Classical conditioning in aged rabbits Delay, trace, and long-delay conditioning . Behav. Neurosci. 110:1996;427-435.
    • (1996) Behav. Neurosci. , vol.110 , pp. 427-435
    • Solomon, P.R.1    Groccia-Ellison, M.2
  • 50
    • 0016770743 scopus 로고
    • Latent inhibition and stimulus generalization of the classically conditioned nictitating membrane response in rabbits (Oryctolagus cuniculus) following dorsal hippocampal ablations
    • Solomon P. R., Moore J. W. Latent inhibition and stimulus generalization of the classically conditioned nictitating membrane response in rabbits (Oryctolagus cuniculus) following dorsal hippocampal ablations. J. Comp. Physio. Psychol. 89:1975;1192-1203.
    • (1975) J. Comp. Physio. Psychol. , vol.89 , pp. 1192-1203
    • Solomon, P.R.1    Moore, J.W.2
  • 51
    • 0020568856 scopus 로고
    • Altered activity in the hippocampus is more detrimental to classical conditioning than removing the structure
    • Solomon P. R., Solomon S. D., Vander Schaaf E., Perry H. E. Altered activity in the hippocampus is more detrimental to classical conditioning than removing the structure. Science. 220:1983;329-331.
    • (1983) Science , vol.220 , pp. 329-331
    • Solomon, P.R.1    Solomon, S.D.2    Vander Schaaf, E.3    Perry, H.E.4
  • 52
    • 0023035964 scopus 로고
    • Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response
    • Solomon P. R., Vander Schaaf E. R., Thompson R. F., Weisz D. J. Hippocampus and trace conditioning of the rabbit's classically conditioned nictitating membrane response. Behav. Neurosci. 100:1986;729-744.
    • (1986) Behav. Neurosci. , vol.100 , pp. 729-744
    • Solomon, P.R.1    Vander Schaaf, E.R.2    Thompson, R.F.3    Weisz, D.J.4
  • 53
    • 0028874565 scopus 로고
    • Nimodipine facilitates retention of the classically conditioned nictitatingmembrane response in aged rabbits over long retention intervals
    • Solomon P. R., Wood M. S., Groccia-Ellison M., Yang B.-Y., Fanelli R. J., Mervis R. F. Nimodipine facilitates retention of the classically conditioned nictitatingmembrane response in aged rabbits over long retention intervals. Neurobiol. Aging. 16:1995;791-796.
    • (1995) Neurobiol. Aging , vol.16 , pp. 791-796
    • Solomon, P.R.1    Wood, M.S.2    Groccia-Ellison, M.3    Yang, B.-Y.4    Fanelli, R.J.5    Mervis, R.F.6
  • 54
    • 0026499201 scopus 로고
    • Disruption of classical eyelid conditioning after cerebellar lesions: Damage to a memory trace system or a simple performance deficit?
    • Steinmetz J. E., Lavond D. G., Ivkovich D., Logan C. G., Thompson R. F. Disruption of classical eyelid conditioning after cerebellar lesions Damage to a memory trace system or a simple performance deficit? J. Neurosci. 12:1992;4403-4426.
    • (1992) J. Neurosci. , vol.12 , pp. 4403-4426
    • Steinmetz, J.E.1    Lavond, D.G.2    Ivkovich, D.3    Logan, C.G.4    Thompson, R.F.5
  • 55
    • 0001797341 scopus 로고
    • Brain substrates of aversive classical conditioning
    • J. IV Madden. New York: Raven Press
    • Steinmetz J. E., Thompson R. F. Brain substrates of aversive classical conditioning. Madden J. IV. Neurobiology of Learning, Emotion, and Affect. 1991;97-120 Raven Press, New York.
    • (1991) Neurobiology of Learning, Emotion, and Affect , pp. 97-120
    • Steinmetz, J.E.1    Thompson, R.F.2
  • 57
    • 0025200248 scopus 로고
    • Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning
    • Thompson L. T., Deyo R. A., Disterhoft J. F. Nimodipine enhances spontaneous activity of hippocampal pyramidal neurons in aging rabbits at a dose that facilitates associative learning. Brain Res. 535:1990;119-130.
    • (1990) Brain Res. , vol.535 , pp. 119-130
    • Thompson, L.T.1    Deyo, R.A.2    Disterhoft, J.F.3
  • 58
    • 0029787589 scopus 로고    scopus 로고
    • Trace eyeblink conditioning in rabbits demonstrates heterogeneity of learning ability both between and within age groups
    • Thompson L. T., Moyer J. R., Disterhoft J. F. Trace eyeblink conditioning in rabbits demonstrates heterogeneity of learning ability both between and within age groups. Neurobiol. Aging. 17:1996;619-629.
    • (1996) Neurobiol. Aging , vol.17 , pp. 619-629
    • Thompson, L.T.1    Moyer, J.R.2    Disterhoft, J.F.3
  • 59
    • 0342572074 scopus 로고
    • Brain substrates of basic associative learning and memory
    • D. Ottoson, T. Bartfai, T. Hokfelt, & K. Fuxe. New York: Pergamon
    • Thompson R. F., Kim J. J., Krupa D. J., Tocco G. Brain substrates of basic associative learning and memory. Ottoson D., Bartfai T., Hokfelt T., Fuxe K. Challenges and Perspectives in Neuroscience. 1995;239-281 Pergamon, New York.
    • (1995) Challenges and Perspectives in Neuroscience , pp. 239-281
    • Thompson, R.F.1    Kim, J.J.2    Krupa, D.J.3    Tocco, G.4
  • 60
    • 0028231217 scopus 로고
    • Organization of memory traces in the mammalian brain
    • Thompson R. F., Krupa D. J. Organization of memory traces in the mammalian brain. Ann. Rev. Neurosci. 17:1994;519-549.
    • (1994) Ann. Rev. Neurosci. , vol.17 , pp. 519-549
    • Thompson, R.F.1    Krupa, D.J.2
  • 62
    • 0027164617 scopus 로고
    • Regionally specific loss of neurons in the aging human hippocampus
    • West M. J. Regionally specific loss of neurons in the aging human hippocampus. Neurobiol. Aging. 14:1993;287-293.
    • (1993) Neurobiol. Aging , vol.14 , pp. 287-293
    • West, M.J.1
  • 63
    • 0027787598 scopus 로고
    • Eyeblink classical conditioning in H.M.: Delay and trace paradigms
    • Woodruff-Pak D. S. Eyeblink classical conditioning in H.M. Delay and trace paradigms . Behav. Neurosci. 107:1993;911-925.
    • (1993) Behav. Neurosci. , vol.107 , pp. 911-925
    • Woodruff-Pak, D.S.1
  • 64
    • 0025613199 scopus 로고
    • Purkinje cell number related to rate of eyeblink classical conditioning
    • Woodruff-Pak D. S., Cronholm J. F., Sheffield J. B. Purkinje cell number related to rate of eyeblink classical conditioning. NeuroReport. 1:1990;165-168.
    • (1990) NeuroReport , vol.1 , pp. 165-168
    • Woodruff-Pak, D.S.1    Cronholm, J.F.2    Sheffield, J.B.3
  • 65
    • 0030989567 scopus 로고    scopus 로고
    • Scopolamine- Or mecamylamine-induced learning impairment: Reversed by nefiracetam
    • Woodruff-Pak D. S., Hinchliffe R. M. Scopolamine- or mecamylamine-induced learning impairment Reversed by nefiracetam . Psychopharmacol. 131:1997;130-139.
    • (1997) Psychopharmacol. , vol.131 , pp. 130-139
    • Woodruff-Pak, D.S.1    Hinchliffe, R.M.2
  • 66
    • 0023092269 scopus 로고
    • Classical conditioning in 3-, 30-, and 45-month-old rabbits: Behavioral learning and hippocampal unit activity
    • Woodruff-Pak D. S., Lavond D. G., Logan C. G., Thompson R. F. Classical conditioning in 3-, 30-, and 45-month-old rabbits Behavioral learning and hippocampal unit activity . Neurobiol. Aging. 8:1987;101-108.
    • (1987) Neurobiol. Aging , vol.8 , pp. 101-108
    • Woodruff-Pak, D.S.1    Lavond, D.G.2    Logan, C.G.3    Thompson, R.F.4
  • 67
    • 0028352414 scopus 로고
    • Nefiracetam (DM-9384): Effect on classical conditioning in older rabbits
    • Woodruff-Pak D. S., Li Y.-T. Nefiracetam (DM-9384) Effect on classical conditioning in older rabbits . Psychopharmacol. 114:1994;200-208.
    • (1994) Psychopharmacol. , vol.114 , pp. 200-208
    • Woodruff-Pak, D.S.1    Li, Y.-T.2
  • 68
    • 0031039999 scopus 로고    scopus 로고
    • Hippocampus in delay eyeblink classical conditioning: Essential for nefiracetam amelioration of leaning in older rabbits
    • Woodruff-Pak D. S., Li Y.-T., Hinchliffe R. M., Port R. L. Hippocampus in delay eyeblink classical conditioning Essential for nefiracetam amelioration of leaning in older rabbits . Brain Res. 747:1997;207-218.
    • (1997) Brain Res. , vol.747 , pp. 207-218
    • Woodruff-Pak, D.S.1    Li, Y.-T.2    Hinchliffe, R.M.3    Port, R.L.4
  • 69
    • 0028341821 scopus 로고
    • Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits
    • Woodruff-Pak D. S., Li Y.-T., Kazmi A., Kem W. R. Nicotinic cholinergic system involvement in eyeblink classical conditioning in rabbits. Behav. Neurosci. 108:1994;486-493.
    • (1994) Behav. Neurosci. , vol.108 , pp. 486-493
    • Woodruff-Pak, D.S.1    Li, Y.-T.2    Kazmi, A.3    Kem, W.R.4
  • 70
    • 0029891416 scopus 로고    scopus 로고
    • The older rabbit as an animal model: Implications for Alzheimer's disease
    • Woodruff-Pak D. S., Trojanowski J. Q. The older rabbit as an animal model Implications for Alzheimer's disease . Neurobiol. Aging. 17:1996;283-290.
    • (1996) Neurobiol. Aging , vol.17 , pp. 283-290
    • Woodruff-Pak, D.S.1    Trojanowski, J.Q.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.