A Bound Water Molecule Is Crucial in Initiating Autocatalytic Precursor Activation in an N-terminal Hydrolase

Journal of Biological Chemistry

Volumn 279, Issue 1, 2004, Pages 341-347

  Yoon, Jongchul ^a   Oh, Bora ^a   Kim, Kyunggon ^a   Park, Jungeun ^a   Han, Dohyun ^a   Kim, Kyeong Kyu ^b   Cha, Sun Shin ^c   Lee, Dongsoon ^a   Kim, Youngsoo ^a  

^a Seoul National University   (South Korea)

^b Sungkyunkwan University   (South Korea)

^c Pohang University of Science and Technology (POSTECH)   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; CATALYSIS; CHEMICAL ACTIVATION; POLARIZATION; WATER;

AUTOPROTEOLYTIC PROCESSING;

BIOCHEMISTRY;

ENZYME PRECURSOR; HYDROLASE; SERINE; WATER;

AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; CRYSTAL STRUCTURE; CRYSTALLIZATION; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME STRUCTURE; MOLECULAR INTERACTION; NUCLEOTIDE SEQUENCE; POLARIZATION; PRIORITY JOURNAL; STRUCTURE ANALYSIS;

CATALYSIS; CRYSTALLOGRAPHY, X-RAY; ENZYME ACTIVATION; ENZYME PRECURSORS; FOURIER ANALYSIS; HYDROGEN BONDING; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PENICILLIN AMIDASE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; PSEUDOMONAS; RECOMBINANT PROTEINS; WATER;

EID: 0347683459     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M309281200     Document Type: Article

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