Analysis of mammalian 20S proteasome biogenesis: The maturation of β-subunits is an ordered two-step mechanism involving autocatalysis

EMBO Journal

Volumn 15, Issue 24, 1996, Pages 6887-6898

  Schmidtke, Gunter ^a   Kraft, Regine ^b   Kostka, Susanne ^b   Henklein, Peter ^a   Frömmel, Cornelius ^a   Löwe, Jan ^c   Huber, Robert ^c   Kloetzel, Peter M ^a   Schmidt, Marion ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^c MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

Author keywords

Autocatalytic activation; Processing mechanism; Proteasome maturation; Structure formation

Indexed keywords

MUTANT PROTEIN; PROTEASOME; RNA 16S;

ARTICLE; AUTOREGULATION; BETA CHAIN; CATALYSIS; CONSENSUS SEQUENCE; CONTROLLED STUDY; DNA TRANSFECTION; ENZYME ACTIVE SITE; ENZYME SUBUNIT; ENZYME SYNTHESIS; HUMAN; HUMAN CELL; POINT MUTATION; PRIORITY JOURNAL; PROTEIN PROCESSING; SITE DIRECTED MUTAGENESIS; STRUCTURE ACTIVITY RELATION;

EID: 0030481129     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb01081.x     Document Type: Article

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