Spongiform degeneration in mahoganoid mutant mice

Science

Volumn 299, Issue 5607, 2003, Pages 710-712

  He, Lin ^a   Lu, Xin Yun ^b   Jolly, Aaron F ^c   Eldridge, Adam G ^a   Watson, Stanley J ^b   Jackson, Peter K ^a   Barsh, Gregory S ^a   Gunn, Teresa M ^c  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^c Department of Population Medicine and Diagnostic Sciences   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENES; PATHOLOGY; PROTEINS;

NEURONAL VIABILITY;

GENETIC ENGINEERING;

ATTRACTIN; GENE PRODUCT; PRION PROTEIN; UBIQUITIN PROTEIN LIGASE; UNCLASSIFIED DRUG;

GENETICS; MUTATION;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN SPONGIOSIS; CELL VIABILITY; ENZYME ACTIVITY; GENE INTERACTION; GENE MUTATION; GENETIC CONSERVATION; MOUSE; MOUSE STRAIN; NONHUMAN; PHENOTYPE; PRION DISEASE; PRIORITY JOURNAL; PROTEIN METABOLISM;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; BLOTTING, NORTHERN; BRAIN; CARRIER PROTEINS; CROSSES, GENETIC; FEMALE; GENE EXPRESSION; LIGASES; MALE; MEMBRANE PROTEINS; MICE; MICE, INBRED C3H; MICE, MUTANT STRAINS; MICE, TRANSGENIC; MODELS, BIOLOGICAL; MOLECULAR SEQUENCE DATA; MUTATION; NEURODEGENERATIVE DISEASES; NEURONS; PIGMENTATION; PRIONS; RECOMBINANT FUSION PROTEINS; RNA, MESSENGER; TRANSGENES; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; VACUOLES;

ANIMALIA;

EID: 0347298778     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1079694     Document Type: Article

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30. nc mice; H. Manuel, S. Shen, and P. Chu for technical assistance; D. Hilton for genetic mapping data; and H. Vogel and V. Lingappa for advice and reagents. Supported by grants from NIH (G,S.B.) and the American Heart Association (T.M.G.).