Synthesis and Structure - Activity Relationship of Mannose-Based Peptidomimetics Selectively Blocking Integrin α4β7 Binding to Mucosal Addressin Cell Adhesion Molecule-1

Journal of Medicinal Chemistry

Volumn 46, Issue 26, 2003, Pages 5752-5762

  Locardi, Elsa ^a   Boer, Jürgen ^a   Modlinger, Armin ^a   Schuster, Anja ^a   Holzmann, Bernhard ^a   Kessler, Horst ^a  

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTEGRIN; INTEGRIN ALPHA4BETA7; INTEGRIN ALPHA4BETA7 BLOCKER; INTEGRIN BLOCKER; MANNOSE; MUCOSAL ADDRESSIN CELL ADHESION MOLECULE 1; PROTEIN INHIBITOR; PYRANOSIDE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BINDING AFFINITY; CHEMICAL BOND; CONFORMATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG SYNTHESIS; PHARMACOPHORE; STRUCTURE ACTIVITY RELATION;

CELL LINE, TUMOR; COMBINATORIAL CHEMISTRY TECHNIQUES; HUMANS; IMMUNOGLOBULINS; INTEGRINS; MANNOSE; MODELS, MOLECULAR; MOLECULAR MIMICRY; MUCOPROTEINS; PEPTIDES; PROTEIN BINDING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0346996359     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020487h     Document Type: Article

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