Generation of dendritic cells from bone marrow progenitors using GM-CSF, TNF-α, and additional cytokines: Antagonistic effects of IL-4 and IFN-γ and selective involvement of TNF-α receptor-1.

Immunology

Volumn 91, Issue 4, 1997, Pages 553-559

  Lardon, F ^a   Snoeck, H W ^a   Berneman, Z N ^a   Van Tendeloo, V F I ^a   Nijs, G ^a   Lenjou, M ^a   Henckaerts, E ^a   Boeckxtaens, C J ^b   Vandenabeele, P ^c   Kestens, L L ^d   Van Bockstaele, D R ^a   Vanham, G L E E ^d  

^a UNIVERSITY OF ANTWERP   (Belgium)

^b ANTWERP UNIVERSITY HOSPITAL   (Belgium)

^c DEPARTMENT OF PLANT SYSTEMS BIOLOGY   (Belgium)

^d INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; GAMMA INTERFERON; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR RECEPTOR;

ANTIGEN PRESENTATION; ARTICLE; BONE MARROW CULTURE; DENDRITIC CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; NORMAL HUMAN; PHENOTYPE; PRIORITY JOURNAL;

EID: 8544247898     PISSN: 00192805     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2567.1997.00295.x     Document Type: Article

References (28)

1. STEINMAN R.M. (1991) The dendritic cell system and its role in immunogenicity. Annu Rev Immunol 9, 271.
2. WILLIAMS L.A., EGNER W. & HART D.N.J. (1994) Isolation and function of human dendritic cells. InI Rev Cytol 153, 41.
3. PETERS J.H., GIESELER R., THIELE B. & STEINBACH H. (1996) Dendritic cells: from ontogenetic orphans to myelomonocytic descendants. Immunol Today 17, 273.
4. LU L., HSIEH M., ORISS T.B., MOREL P.A., STARZL T.E., RAO A.S. & THOMSON A.W. (1995) Generation of DC from mouse spleen cultures in response to GM-CSF: immunophenotypic and functional analyses. Immunology 84, 127.
5. CAUX C., DEZUTTER-DAMBUYANT C., SCHMITT D. & BANCHEREAU J. (1992) GM-CSF and TNF-α cooperate in the generation of dendritic Langerhans cells. Nature 360, 258.
6. SANTIAGO-SCHWARZ F., DIVARIS N., KAY C. & CARSONS S.E. (1993) Mechanisms of tumor necrosis factor-granulocyte-macrophage colony-stimulating factor-induced dendritic cell development. Blood 82, 3019.
7. + hematopoietic precursor cells. Blood 87, 535.
8. SANTIAGO-SCHWARZ F., RAPPA D.A., LAKY K. & CARSONS S.E. (1995) Stem cell factor augments tumor necrosis factor-granulocyte-macrophage colony-stimulating factor-mediated dendritic cell hematopoiesis. Stem Cells 13, 186.
9. FREEDMAN A.S., FREEMAN G.J., RHYNHART K. & NADLER L.M. (1991) Selective induction of B7/BB1 on interferon-gamma stimulated monocytes: a potential mechanism for amplification of T cell activation through the CD28 pathway. Cell Immunol 137, 429.
10. SNOECK H.W., LENJOU M., NYS G. et al. (1996) Interleukin 4 and interferon γ costimulate the expansion of early human myeloid colony-forming cells. Proposal of a model for the regulation of myelopoiesis by interleukin 4 and interferon γ and its integration with the regulation of the immune response. Leukemia 10, 117.
11. SCHALL T.J., LEWIS M., KOLLER K.J. et al. (1990) Molecular cloning and expression of a receptor for human tumor necrosis factor. Cell 61, 361.
12. TARTAGLIA L.A. & GOEDDEL D.V. (1992) Two TNF receptors. Immunol Today 13, 151.
13. VAN OSTADE X., VANDENABEELE P., EVERAERDT B. et al. (1993) Human TNF mutants with selective activity on the p55 receptor. Nature 361, 266.
14. LOETSCHER H., STUEBER D., BANNER D., MACKAY F. & LESSLAUER W. (1993) Human tumor necrosis factor α (TNF α) mutants with exclusive specificity for the 55-kDa or 75-kDa TNF receptors. J Biol Chem 268, 26 350.
15. VAN OSTADE X., VANDENABEELE P., TAVERNIER J. & FIERS W. (1994) Human tumor necrosis factor mutants with preferential binding and activity on either the R55 or R75 receptor. Eur J Biochem 220, 771.
16. VANDENABEELE P., DECLERCQ W., BEYAERT R. & FIERS W. (1995) Two tumour necrosis factor receptors: structure and function. Trends Cell Biol 5, 392.
17. BÜHRING H.-J., ULLRICH A., SCHAUDT K., MUdie;LLER C.A. & BUSCH W. (1991) The product of the proto-oncogene c-kit (P145ckit) is a human bone marrow surface antigen of hematopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic leukemic cells. Leukemia 5, 854.
18. + bone marrow progenitors that are expanded by c-kit-ligand and yield pure dendritic cell colonies in the presence of granulocyte macrophage colony-stimulating factor and tumor necrosis factor α. J Exp Med 182, 1111.
19. + bone marrow precursors cultured with c-kit ligand, GM-CSF and TNF-α. J Immunol 154, 5851.
20. SZABOLCS P., AVIGAN D., GEZELTER S. et al (1996) Dendritic cells and macrophages can mature independently from a human bone marrow-derived, post-colony-forming unit intermediate. Blood 87, 4520.
21. TRINCHIERI G. & PERUSSIA B. (1985) Immune interferon: a pleiotropic lymphokine with multiple effects. Immunol Today 6, 131.
22. DE MAEYER E. & DE MAEYER-GUIGNARD J. (1992) Interferon-γ. Curr Opin Immunol 4, 321.
23. OZAWA H., AIBA S., NAKAGAWA S. & TAGAMI H. (1996) Interferon-γ and interleukin-10 inhibit antigen presentation by Langerhans cells for T helper type 1 cells by suppressing their CD80 (B7-1) expression. Eur J Immunol 26, 648.
24. + human marrow cells is induced by interferon γ and tumor necrosis factor α and potentiates cytokine-mediated hematopoietic suppression in vitro. Blood 85, 3183.
25. CELLA M., SCHEIDEGGER D., PALMER-LEHMANN K., LANE P., LANZAVECCHIA A. & ALBER G. (1996) Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J Exp Med 184, 747.
26. SNOECK H.-W., LARDON F., LENJOU M., NYS G., VAN BOCKSTAELE D.R. & PEETERMANS M.E. (1993) Interferon-γ and interleukin-4 reciprocally regulate the production of monocytes macrophages and neutrophils through a direct effect on committed monopotential bone marrow progenitor cells. Eur J Immunol 23, 1072.
27. ABBAS A.K., MURPHY K.M. & SHER A. (1996) Functional diversity of helper T lymphocytes. Nature 383, 787.
28. RUSTEN L.S., JACOBSEN F.W., LESSLAUER W., LOETSCHER H., SMELAND E.B. & JACOBSEN S.E.W. (1994) Bifunctional effects of tumor necrosis factor α (TNF α) on the growth of mature and primitive human hematopoietic progenitor cells: involvement of p55 and p75 TNF receptors. Blood 83, 3152.