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Volumn 78, Issue 2, 2004, Pages 692-699

Effects of Altering the Transcription Termination Signals of Respiratory Syncytial Virus on Viral Gene Expression and Growth in Vitro and in Vivo

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; UNCLASSIFIED DRUG; VIRUS ENZYME; VIRUS POLYMERASE; VIRUS PROTEIN;

EID: 0346688649     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.78.2.692-699.2004     Document Type: Article
Times cited : (12)

References (28)
  • 1
    • 0031907721 scopus 로고    scopus 로고
    • The NS1 protein of human respiratory syncytial virus is a potent inhibitor of minigenome transcription and RNA replication
    • Atreya, P. L., M. E. Peeples, and P. L. Collins. 1998. The NS1 protein of human respiratory syncytial virus is a potent inhibitor of minigenome transcription and RNA replication. J. Virol. 72:1452-1461.
    • (1998) J. Virol. , vol.72 , pp. 1452-1461
    • Atreya, P.L.1    Peeples, M.E.2    Collins, P.L.3
  • 2
    • 0031041583 scopus 로고    scopus 로고
    • Role of the intergenic dinucleotide in vesicular stomatitis virus RNA transcription
    • Barr, J. N., S. P. Whelan, and G. W. Wertz. 1997. Role of the intergenic dinucleotide in vesicular stomatitis virus RNA transcription. J. Virol. 71:1794-1801.
    • (1997) J. Virol. , vol.71 , pp. 1794-1801
    • Barr, J.N.1    Whelan, S.P.2    Wertz, G.W.3
  • 3
    • 0036312053 scopus 로고    scopus 로고
    • The long noncoding region of the human parainfluenza virus type 1 F gene contributes to the read-through transcription at the M-F gene junction
    • Bousse, T., T. Matrosovich, A. Portner, A. Kato, Y. Nagai, and T. Takimoto. 2002. The long noncoding region of the human parainfluenza virus type 1 F gene contributes to the read-through transcription at the M-F gene junction. J. Virol. 76:8244-8251.
    • (2002) J. Virol. , vol.76 , pp. 8244-8251
    • Bousse, T.1    Matrosovich, T.2    Portner, A.3    Kato, A.4    Nagai, Y.5    Takimoto, T.6
  • 4
    • 0032888955 scopus 로고    scopus 로고
    • Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter
    • Buchholz, U. J., S. Finke, and K. K. Conzelmann. 1999. Generation of bovine respiratory syncytial virus (BRSV) from cDNA: BRSV NS2 is not essential for virus replication in tissue culture, and the human RSV leader region acts as a functional BRSV genome promoter. J. Virol. 73:251-259.
    • (1999) J. Virol. , vol.73 , pp. 251-259
    • Buchholz, U.J.1    Finke, S.2    Conzelmann, K.K.3
  • 5
    • 0030782367 scopus 로고    scopus 로고
    • Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse
    • Bukreyev, A., S. S. Whitehead, B. R. Murphy, and P. L. Collins. 1997. Recombinant respiratory syncytial virus from which the entire SH gene has been deleted grows efficiently in cell culture and exhibits site-specific attenuation in the respiratory tract of the mouse. J. Virol. 71:8973-8982.
    • (1997) J. Virol. , vol.71 , pp. 8973-8982
    • Bukreyev, A.1    Whitehead, S.S.2    Murphy, B.R.3    Collins, P.L.4
  • 6
    • 0000768105 scopus 로고    scopus 로고
    • Respiratory syncytial virus
    • D. M. Knipe and P. M. Howley (ed.). Lippincott, Williams and Wilkins, Philadelphia, Pa
    • Collins, P. L., R. M. Chanock, and B. R. Murphy. 2001. Respiratory syncytial virus, p. 1443-1485. In D. M. Knipe and P. M. Howley (ed.), Fields virology, 4th ed. Lippincott, Williams and Wilkins, Philadelphia, Pa.
    • (2001) Fields Virology, 4th Ed. , pp. 1443-1485
    • Collins, P.L.1    Chanock, R.M.2    Murphy, B.R.3
  • 7
    • 0022504445 scopus 로고
    • Nucleotide sequences for the gene junctions of human respiratory syncytial virus reveal distinctive features of intergenic structure and gene order
    • Collins, P. L., L. E. Dickens, A. Buckler-White, R. A. Olmsted, M. K. Spriggs, E. Camargo, and K. V. Coelingh. 1986. Nucleotide sequences for the gene junctions of human respiratory syncytial virus reveal distinctive features of intergenic structure and gene order. Proc. Natl. Acad. Sci. USA 83:4594-4598.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 4594-4598
    • Collins, P.L.1    Dickens, L.E.2    Buckler-White, A.3    Olmsted, R.A.4    Spriggs, M.K.5    Camargo, E.6    Coelingh, K.V.7
  • 8
    • 0029584042 scopus 로고
    • Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5′ proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development
    • Collins, P. L., M. G. Hill, E. Camargo, H. Grosfeld, R. M. Chanock, and B. R. Murphy. 1995. Production of infectious human respiratory syncytial virus from cloned cDNA confirms an essential role for the transcription elongation factor from the 5′ proximal open reading frame of the M2 mRNA in gene expression and provides a capability for vaccine development. Proc. Natl. Acad. Sci. USA 92:11563-11567.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 11563-11567
    • Collins, P.L.1    Hill, M.G.2    Camargo, E.3    Grosfeld, H.4    Chanock, R.M.5    Murphy, B.R.6
  • 9
    • 0020563343 scopus 로고
    • cDNA cloning and transcriptional mapping of nine polyadenylylated RNAs encoded by the genome of human respiratory syncytial virus
    • Collins, P. L., and G. W. Wertz. 1983. cDNA cloning and transcriptional mapping of nine polyadenylylated RNAs encoded by the genome of human respiratory syncytial virus. Proc. Natl. Acad. Sci. USA 80:3208-3212.
    • (1983) Proc. Natl. Acad. Sci. USA , vol.80 , pp. 3208-3212
    • Collins, P.L.1    Wertz, G.W.2
  • 11
    • 0032889282 scopus 로고    scopus 로고
    • Diverse gene junctions of respiratory syncytial virus modulate the efficiency of transcription termination and respond differently to M2-mediated antitermination
    • Hardy, R. W., S. B. Harmon, and G. W. Wertz. 1999. Diverse gene junctions of respiratory syncytial virus modulate the efficiency of transcription termination and respond differently to M2-mediated antitermination. J. Virol. 73:170-176.
    • (1999) J. Virol. , vol.73 , pp. 170-176
    • Hardy, R.W.1    Harmon, S.B.2    Wertz, G.W.3
  • 12
    • 0036390013 scopus 로고    scopus 로고
    • Transcriptional termination modulated by nucleotides outside the characterized gene end sequence of respiratory syncytial virus
    • Harmon, S., and G. Wertz. 2002. Transcriptional termination modulated by nucleotides outside the characterized gene end sequence of respiratory syncytial virus. Virology 300:304-315.
    • (2002) Virology , vol.300 , pp. 304-315
    • Harmon, S.1    Wertz, G.2
  • 13
    • 0034749389 scopus 로고    scopus 로고
    • RNA sequences involved in transcriptional termination of respiratory syncytial virus
    • Harmon, S. B., A. G. Megaw, and G. W. Wertz. 2001. RNA sequences involved in transcriptional termination of respiratory syncytial virus. J. Virol. 75:36-44.
    • (2001) J. Virol. , vol.75 , pp. 36-44
    • Harmon, S.B.1    Megaw, A.G.2    Wertz, G.W.3
  • 14
    • 0032775471 scopus 로고    scopus 로고
    • Effect of inserting paramyxovirus simian virus 5 gene junctions at the HN/L gene junction: Analysis of accumulation of mRNAs transcribed from rescued viable viruses
    • He, B., and R. A. Lamb. 1999. Effect of inserting paramyxovirus simian virus 5 gene junctions at the HN/L gene junction: analysis of accumulation of mRNAs transcribed from rescued viable viruses. J. Virol. 73:6228-6234.
    • (1999) J. Virol. , vol.73 , pp. 6228-6234
    • He, B.1    Lamb, R.A.2
  • 15
    • 0019524183 scopus 로고
    • Localized attenuation and discontinuous synthesis during vesicular stomatitis virus transcription
    • Iverson, L. E., and J. K. Rose. 1981. Localized attenuation and discontinuous synthesis during vesicular stomatitis virus transcription. Cell 23:477-484.
    • (1981) Cell , vol.23 , pp. 477-484
    • Iverson, L.E.1    Rose, J.K.2
  • 16
    • 0033988235 scopus 로고    scopus 로고
    • Respiratory syncytial virus that lacks open reading frame 2 of the M2 gene (M2-2) has altered growth characteristics and is attenuated in rodents
    • Jin, H., X. Cheng, H. Z. Zhou, S. Li, and A. Seddiqui. 2000. Respiratory syncytial virus that lacks open reading frame 2 of the M2 gene (M2-2) has altered growth characteristics and is attenuated in rodents. J. Virol. 74:74-82.
    • (2000) J. Virol. , vol.74 , pp. 74-82
    • Jin, H.1    Cheng, X.2    Zhou, H.Z.3    Li, S.4    Seddiqui, A.5
  • 17
    • 0023613953 scopus 로고
    • Rapid and efficient site-specific mutagenesis without phenotypic selection
    • Kunkel, T. A., J. D. Roberts, and R. A. Zakour. 1987. Rapid and efficient site-specific mutagenesis without phenotypic selection. Methods Enzymol. 154:367-382.
    • (1987) Methods Enzymol. , vol.154 , pp. 367-382
    • Kunkel, T.A.1    Roberts, J.D.2    Zakour, R.A.3
  • 18
    • 0030953647 scopus 로고    scopus 로고
    • Analysis of the gene start and gene end signals of human respiratory syncytial virus: Quasi-templated initiation at position 1 of the encoded mRNA
    • Kuo, L., R. Fearns, and P. L. Collins. 1997. Analysis of the gene start and gene end signals of human respiratory syncytial virus: quasi-templated initiation at position 1 of the encoded mRNA. J. Virol. 71:4944-4953.
    • (1997) J. Virol. , vol.71 , pp. 4944-4953
    • Kuo, L.1    Fearns, R.2    Collins, P.L.3
  • 19
    • 0029817031 scopus 로고    scopus 로고
    • The structurally diverse intergenic regions of respiratory syncytial virus do not modulate sequential transcription by a dicistronic minigenome
    • Kuo, L., R. Fearns, and P. L. Collins. 1996. The structurally diverse intergenic regions of respiratory syncytial virus do not modulate sequential transcription by a dicistronic minigenome. J. Virol. 70:6143-6150.
    • (1996) J. Virol. , vol.70 , pp. 6143-6150
    • Kuo, L.1    Fearns, R.2    Collins, P.L.3
  • 20
    • 0001178028 scopus 로고    scopus 로고
    • Paramyxoviridae: The viruses and their replication
    • D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Strauss (ed.). Lippincott Williams & Wilkins, Philadelphia, Pa
    • Lamb, R. A., and D. Kolakofsky. 2001. Paramyxoviridae: the viruses and their replication, p. 1305-1340. In D. M. Knipe, P. M. Howley, D. E. Griffin, R. A. Lamb, M. A. Martin, B. Roizman, and S. E. Strauss (ed.), Fields virology, vol. 1. Lippincott Williams & Wilkins, Philadelphia, Pa.
    • (2001) Fields Virology , vol.1 , pp. 1305-1340
    • Lamb, R.A.1    Kolakofsky, D.2
  • 21
    • 0025052448 scopus 로고
    • Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization
    • Murphy, B. R., A. V. Sotnikov, L. A. Lawrence, S. M. Banks, and G. A. Prince. 1990. Enhanced pulmonary histopathology is observed in cotton rats immunized with formalin-inactivated respiratory syncytial virus (RSV) or purified F glycoprotein and challenged with RSV 3-6 months after immunization. Vaccine 8:497-502.
    • (1990) Vaccine , vol.8 , pp. 497-502
    • Murphy, B.R.1    Sotnikov, A.V.2    Lawrence, L.A.3    Banks, S.M.4    Prince, G.A.5
  • 22
    • 0035975620 scopus 로고    scopus 로고
    • Synergistic effects of gene-end signal mutations and the m2-1 protein on transcription termination by respiratory syncytial virus
    • Sutherland, K. A., P. L. Collins, and M. E. Peeples. 2001. Synergistic effects of gene-end signal mutations and the m2-1 protein on transcription termination by respiratory syncytial virus. Virology 288:295-307.
    • (2001) Virology , vol.288 , pp. 295-307
    • Sutherland, K.A.1    Collins, P.L.2    Peeples, M.E.3
  • 23
    • 0032889254 scopus 로고    scopus 로고
    • Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein
    • Teng, M. N., and P. L. Collins. 1999. Altered growth characteristics of recombinant respiratory syncytial viruses which do not produce NS2 protein. J. Virol. 73:466-473.
    • (1999) J. Virol. , vol.73 , pp. 466-473
    • Teng, M.N.1    Collins, P.L.2
  • 24
    • 0033803734 scopus 로고    scopus 로고
    • Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees
    • Teng, M. N., S. S. Whitehead, A. Bermingham, M. St. Claire, W. R. Elkins, B. R. Murphy, and P. L. Collins. 2000. Recombinant respiratory syncytial virus that does not express the NS1 or M2-2 protein is highly attenuated and immunogenic in chimpanzees. J. Virol. 74:9317-9321.
    • (2000) J. Virol. , vol.74 , pp. 9317-9321
    • Teng, M.N.1    Whitehead, S.S.2    Bermingham, A.3    St. Claire, M.4    Elkins, W.R.5    Murphy, B.R.6    Collins, P.L.7
  • 25
    • 0036079140 scopus 로고    scopus 로고
    • Recombinant Sendai viruses expressing different levels of a foreign reporter gene
    • Tokusumi, T., A. Iida, T. Hirata, A. Kato, Y. Nagai, and M. Hasegawa. 2002. Recombinant Sendai viruses expressing different levels of a foreign reporter gene. Virus Res. 86:33-38.
    • (2002) Virus Res. , vol.86 , pp. 33-38
    • Tokusumi, T.1    Iida, A.2    Hirata, T.3    Kato, A.4    Nagai, Y.5    Hasegawa, M.6
  • 26
    • 0036315015 scopus 로고    scopus 로고
    • Adding genes to the RNA genome of vesicular stomatitis virus: Positional effects on stability of expression
    • Wertz, G. W., R. Moody, and L. A. Ball. 2002. Adding genes to the RNA genome of vesicular stomatitis virus: positional effects on stability of expression. J. Virol. 76:7642-7650.
    • (2002) J. Virol. , vol.76 , pp. 7642-7650
    • Wertz, G.W.1    Moody, R.2    Ball, L.A.3
  • 28
    • 0032145583 scopus 로고    scopus 로고
    • A single nucleotide substitution in the transcription start signal of the M2 gene of respiratory syncytial virus vaccine candidate cpts248/404 is the major determinant of the temperature-sensitive and attenuation phenotypes
    • Whitehead, S. S., C. Y. Firestone, P. L. Collins, and B. R. Murphy. 1998. A single nucleotide substitution in the transcription start signal of the M2 gene of respiratory syncytial virus vaccine candidate cpts248/404 is the major determinant of the temperature-sensitive and attenuation phenotypes. Virology 247:232-239.
    • (1998) Virology , vol.247 , pp. 232-239
    • Whitehead, S.S.1    Firestone, C.Y.2    Collins, P.L.3    Murphy, B.R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.