Neuronal endosomal/lysosomal membrane destabilization activates caspases and induces abnormal accumulation of the lipid secondary messenger ceramide

Brain Research Bulletin

Volumn 59, Issue 6, 2003, Pages 523-531

  Ditaranto Desimone, Kristen ^b   Saito, Mitsuo ^b   Tekirian, T L ^c   Saito, Mariko ^b   Berg, Martin ^b   Dubowchik, Gene ^d   Soreghan, Brian ^a   Thomas, Stefani ^a   Marks, Neville ^b   Yang, Austin J ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^b NATHAN S KLINE INSTITUTE FOR PSYCHIATRIC RESEARCH   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 3; CERAMIDE; LIPOFUSCIN; SPHINGOMYELIN;

AGING; ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; ENDOSOME; ENZYME ACTIVATION; HYDROLYSIS; LIPID STORAGE; LYSOSOME; MOUSE; NERVE CELL; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SENSITIZATION;

ANIMALS; CASPASES; CELL DEATH; CELLS, CULTURED; CERAMIDES; DETERGENTS; ENDOSOMES; ENZYME INHIBITORS; FEMALE; INTRACELLULAR MEMBRANES; LYSOSOMES; MICE; NEURONS; PREGNANCY; SECOND MESSENGER SYSTEMS;

EID: 0037441739     PISSN: 03619230     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0361-9230(02)00948-6     Document Type: Article

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