Morphological assessment of the development of multinucleated giant cells in glioma by using mitosis-specific phosphorylated antibodies

Journal of Neurosurgery

Volumn 98, Issue 4, 2003, Pages 854-859

  Maeda, Kenkou ^b   Mizuno, Masaaki ^b   Wakabayashi, Toshihiko ^a   Takasu, Syuntarou ^b   Nagasaka, Tetsurou ^b   Inagaki, Masaki ^b   Yoshida, Jun ^b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NONE

Author keywords

Glial fibrillary acidic protein; Multinucleated giant cell; Phosphorylation; Vimentin

Indexed keywords

GLIAL FIBRILLARY ACIDIC PROTEIN; MONOCLONAL ANTIBODY; VIMENTIN;

ARTICLE; BRAIN TUMOR; CASE REPORT; CELL STRUCTURE; CONFOCAL LASER MICROSCOPY; GIANT CELL; GLIOMA; GLIOMA CELL; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MITOSIS; MORPHOLOGY; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION;

EID: 0345701927     PISSN: 00223085     EISSN: None     Source Type: Journal    
DOI: 10.3171/jns.2003.98.4.0854     Document Type: Article

References (41)

1. Biernat W, Kleihues P, Yonekawa Y, et al: Amplification and overexpression of MDM2 in primary (de novo) glioblastomas. J Neuropathol Exp Neurol 56:180-185, 1997
2. Biernat W, Tohma Y, Yonekawa Y, et al: Alterations of cell cycle regulatory genes in primary (de novo) and secondary glioblastomas. Acta Neuropathol 94:303-309, 1997
3. Bostrom J, Cobbers JM, Wolter M, et al: Mutation of the PTEN (MMAC1) tumor suppressor gene in a subset of glioblastomas but not in meningiomas with loss of chromosome arm 10q. Cancer Res 58:29-33, 1998
4. Chou YH, Ngai KL, Goldman R: The regulation of intermediate filament reorganization in mitosis. P34cdc2 phosphorylates vimentin at a unique N-terminal site. J Biol Chem 266:7325-7328, 1991
5. Czernik AJ, Girault JA, Naim AC, et al: Production of phosphorylation state-specific antibodies. Methods Enzymol 201:264-283, 1991
6. Duerr EM, Rollbrocker B, Hayashi Y, et al: PTEN mutations in gliomas and glioneuronal tumors. Oncogene 16:2259-2264, 1998
7. Giangaspero F, Burger PC: Correlation between cytologic composition and biologic behavior in the glioblastoma multiforme. A postmortem study of 50 cases. Cancer 52:2320-2333, 1983
8. Giangaspero F, Doglioni C, Rivano MT, et al: Growth fraction in human brain tumors defined by the monoclonal antibody Ki-67. Acta Neuropathol 74:179-182, 1987
9. Goto H, Kosako H, Inagaki M: Regulation of intermediate filament organization during cytokinesis: possible roles of Rho-associated kinase. Microsc Res Tech 49:173-182, 2000
10. Goto H, Kosako H, Tanabe K, et al: Phosphorylation of vimentin by Rho-associated kinase at a unique amino-terminal site that is specifically phophorylated during cytokinesis. J Biol Chem 273:11728-11736, 1998
11. Huang MC, Kubo O, Tajika Y, et al: A clinico-immunohistochemical study of giant cell glioblastoma. Noshuyo Byori 13:11-16, 1996
12. Inagaki M, Inagaki N, Takahashi T, et al: Phosphorylation-dependent control of structures of intermediate filaments: a novel approach using site- and phosphorylation state-specific antibodies. J Biochem 121:407-414, 1997
13. Inagaki M, Matsuoka Y, Tsujimura K, et al: Dynamic property of intermediate filaments: regulation by phophorylation. Bioessays 18:481-487, 1996
14. Inagaki M, Nakamura Y, Takeda M, et al: Glial fibrillary acidic protein: dynamic property and regulation by phosphorylation. Brain Pathol 4:239-243, 1994
15. Inagaki N, Goto H, Ogawara M, et al: Spatial patterns of Ca2+ signals define intracellular distribution of a singaling by Ca2+/Calmodulin-dependent protein kinase II. J Biol Chem 272:25195-25199, 1997
16. Kamei Y, Inagaki N, Nishizawa M, et al: Visualization of mitotic radial glial lineage cells in the developing rat brain by Cdc2 kinase-phosphorylated vimentin. Glia 23:191-199, 1998
17. Katoh M, Aida T, Sugimoto S, et al: Immunohistochemical analysis of giant cell glioblastoma. Pathol Int 45:275-282, 1995
18. Kosako H, Amano M, Yanagida M, et al: Phosphorylation of glial fibrillary acidic protein at the same sites by cleavage furrow kinase and Rho-associated kinase. J Biol Chem 272:10333-10336, 1997
19. Kosako H, Goto H, Yanagida M, et al: Specific accumulation of Rho-associated kinase at the cleavage furrow: cleavage furrow-specific phophorylation of intermediate filaments. Oncogene 18:2783-2788, 1999
20. cdc2 kinase for intermediate filament proteins, in vitro. J Biol Chem 267:20937-20942, 1992
21. Lazarides E: Intermediate filaments as mechanical integrators of cellular space. Nature 283:249-256, 1980
22. Madaule P, Eda M, Watanabe N, et al: Role of citron kinase as a target of the small GTPase Rho in cytokinesis. Nature 394:491-494, 1998
23. Matsuoka Y, Nishizawa K, Yano T, et al: Two different protein kinases act on a different time schedule as glial filament kinases during mitosis. EMBO J 11:2895-2902, 1992
24. Meyer-Puttlitz B, Hayashi Y, Waha A, et al: Molecular genetic analysis of giant cell glioblastomas. Am J Pathol 151:853-857, 1997
25. Muller W, Slowik F, Firsching R, et al: Contribution to the problem of giant cell astrocytomas. Neurosurg Rev 10:213-219, 1987
26. Nishizawa K, Yano T, Shibata M, et al: Specific localization of phosphointermediate filament protein in the constricted area of dividing cells. J Biol Chem 266:3074-3079, 1991
27. Ogawara M, Inagaki N, Tsujimura K, et al: Differential targeting of protein kinase C and CaM kinase II signalings to vimentin. J Cell Biol 131:1055-1066, 1995
28. Palma L, Celli P, Maleci A, et al: Malignant monstrocellular brain tumours. A study of 42 surgically treated cases. Acta Neurochir 97:17-25, 1989
29. Peraud A, Watanabe K, Plate KH, et al: p53 mutations versus EGF receptor expression in giant cell glioblastomas. J Neuropathol Exp Neurol 56:1236-1241, 1997
30. Peraud A, Watanabe K, Schwechheimer K, et al: Genetic profile of the giant cell glioblastoma. Lab Invest 79:123-129, 1999
31. Rasheed BKA, Stenzel TT, McLendon RE, et al: PTEN gene mutations are seen in high-grade but not in low-grade gliomas. Cancer Res 57:4187-4190, 1997
32. Sekimata, M, Tsujimura K, Tanaka J, et al: Detection of protein kinase activity specifically activated at metaphase-anaphase transition. J Cell Biol 132:635-641, 1996
33. Steinert PM, Roop DR: Molecular and cellular biology of intermediate filaments. Annu Rev Biochem 57:593-625, 1988
34. Takai Y, Inagaki M: [Intracelluar distribution of active form of intermediate filament kinases.] Cell Technol 15:296-303, 1996 (Jpn)
35. Takai Y, Ogawara M, Tomono Y, et al: Mitosis-specific phosphorylation of vimentin by protein kinase C coupled with reorganization of intracellular membranes. J Cell Biol 133:141-149, 1996
36. Tohma Y, Gratas C, Biernat W, et al: PTEN (MMAC1) mutations are frequent in primary glioblastomas (de novo) but not in secondary glioblastomas. J Neuropathol Exp Neurol 57:684-689, 1998
37. Tsujimura K, Ogawara M, Takeuchi Y, et al: Visualization and function of vimentin phosphorylation by cdc2 kinase during mitosis. J Biol Chem 269:31097-31106, 1994
38. Wang SI, Puc J, Li J, et al: Somatic mutations of PTEN in glioblastoma multiforme. Cancer Res 57:4183-4186, 1997
39. Watanabe K, Tachibana O, Sata K, et al: Overexpression of the EGF receptor and p53 mutations are mutually exclusive in the evolution of primary and secondary glioblastomas. Brain Pathol 6:217-224, 1996
40. Yano T, Taura C, Shibata M, et al: A monoclonal antibody to the phophorylated form of glial fibrillary acidic protein: application to a non-radioactive method for measuring protein kinase activities. Biochem Biophys Res Commun 175:1144-1151, 1991
41. Yoshida M, Usui T, Tsujimura K, et al: Biochemical differences between staurosporine-induced apoptosis and premature mitosis. Exp Cell Res 232:225-239, 1997