메뉴 건너뛰기




Volumn 2, Issue 12, 2003, Pages 1321-1335

MEC1-dependent phosphorylation of yeast RPA1 in vitro

Author keywords

Checkpoint kinase; Phosphorylation; Replication protein A; RPA1; Single stranded DNA

Indexed keywords

KINASE MEC1; MUTANT PROTEIN; PHOSPHOTRANSFERASE; PROTEIN RFA1 S178A; PROTEIN SUBUNIT; REPLICATION PROTEIN A; REPLICATION PROTEIN A1; REPLICATION PROTEIN A2; UNCLASSIFIED DRUG;

EID: 0345293222     PISSN: 15687864     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.dnarep.2003.07.004     Document Type: Article
Times cited : (33)

References (53)
  • 1
    • 0030908093 scopus 로고    scopus 로고
    • RPA: A heterotrimeric, single-stranded DNA binding protein required for eukaryotic DNA metabolism
    • Wold M.S. RPA: A heterotrimeric, single-stranded DNA binding protein required for eukaryotic DNA metabolism. Annu. Rev. Biochem. 66:1997;61-91.
    • (1997) Annu. Rev. Biochem. , vol.66 , pp. 61-91
    • Wold, M.S.1
  • 2
    • 0026772415 scopus 로고
    • Binding properties of replication protein a from human and yeast cells
    • Kim C., Snyder R.O., Wold M.S. Binding properties of replication protein A from human and yeast cells. Mol. Cell. Biol. 12:1992;3050-3059.
    • (1992) Mol. Cell. Biol. , vol.12 , pp. 3050-3059
    • Kim, C.1    Snyder, R.O.2    Wold, M.S.3
  • 3
    • 0028957756 scopus 로고
    • Recombinant human replication protein a binds to polynucleotides with low cooperativity
    • Kim C., Wold M.S. Recombinant human replication protein A binds to polynucleotides with low cooperativity. Biochemistry. 34:1995;2058-2064.
    • (1995) Biochemistry , vol.34 , pp. 2058-2064
    • Kim, C.1    Wold, M.S.2
  • 5
    • 0031030449 scopus 로고    scopus 로고
    • Structure of the single-stranded-DNA-binding domain of replication protein a bound to DNA
    • Bochkarev A., Pfuetzner R.A., Edwards A.M., Frappier L. Structure of the single-stranded-DNA-binding domain of replication protein A bound to DNA. Nature. 385:1997;176-181.
    • (1997) Nature , vol.385 , pp. 176-181
    • Bochkarev, A.1    Pfuetzner, R.A.2    Edwards, A.M.3    Frappier, L.4
  • 6
    • 0031753251 scopus 로고    scopus 로고
    • Identification and characterization of the fourth single-stranded-DNA binding domain of replication protein a
    • Brill S.J., Bastin-Shanower S. Identification and characterization of the fourth single-stranded-DNA binding domain of replication protein A. Mol. Cell. Biol. 18:1998;7225-7234.
    • (1998) Mol. Cell. Biol. , vol.18 , pp. 7225-7234
    • Brill, S.J.1    Bastin-Shanower, S.2
  • 7
    • 0035965188 scopus 로고    scopus 로고
    • Functional analysis of the four DNA binding domains of Replication protein A: The role of RPA2 in ssDNA binding
    • Bastin-Shanower S.A., Brill S.J. Functional analysis of the four DNA binding domains of Replication protein A: the role of RPA2 in ssDNA binding. J. Biol. Chem. 276:2001;36446-36453.
    • (2001) J. Biol. Chem. , vol.276 , pp. 36446-36453
    • Bastin-Shanower, S.A.1    Brill, S.J.2
  • 8
    • 0033575671 scopus 로고    scopus 로고
    • The crystal structure of the complex of replication protein a subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding
    • Bochkarev A., Bochkareva E., Frappier L., Edwards A.M. The crystal structure of the complex of replication protein A subunits RPA32 and RPA14 reveals a mechanism for single-stranded DNA binding. EMBO J. 18:1999;4498-4504.
    • (1999) EMBO J. , vol.18 , pp. 4498-4504
    • Bochkarev, A.1    Bochkareva, E.2    Frappier, L.3    Edwards, A.M.4
  • 9
    • 0032836911 scopus 로고    scopus 로고
    • Human replication protein A: Global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker
    • Jacobs D.M., Lipton A.S., Isern N.G., Daughdrill G.W., Lowry D.F., Gomes X., Wold M.S. Human replication protein A: global fold of the N-terminal RPA-70 domain reveals a basic cleft and flexible C-terminal linker. J. Biomol. NMR. 14:1999;321-331.
    • (1999) J. Biomol. NMR , vol.14 , pp. 321-331
    • Jacobs, D.M.1    Lipton, A.S.2    Isern, N.G.3    Daughdrill, G.W.4    Lowry, D.F.5    Gomes, X.6    Wold, M.S.7
  • 10
    • 0031960691 scopus 로고    scopus 로고
    • Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism
    • Umezu K., Sugawara N., Chen C., Haber J.E., Kolodner R.D. Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism. Genetics. 148:1998;989-1005.
    • (1998) Genetics , vol.148 , pp. 989-1005
    • Umezu, K.1    Sugawara, N.2    Chen, C.3    Haber, J.E.4    Kolodner, R.D.5
  • 11
    • 0029868656 scopus 로고    scopus 로고
    • Proteolytic mapping of human replication protein A: Evidence for multiple structural domains and a conformational change upon interaction with single-stranded DNA
    • Gomes X.V., Henricksen L.A., Wold M.S. Proteolytic mapping of human replication protein A: evidence for multiple structural domains and a conformational change upon interaction with single-stranded DNA. Biochemistry. 35:1996;5586-5595.
    • (1996) Biochemistry , vol.35 , pp. 5586-5595
    • Gomes, X.V.1    Henricksen, L.A.2    Wold, M.S.3
  • 12
    • 0030848209 scopus 로고    scopus 로고
    • Role of protein-protein interactions in the function of replication protein a (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms
    • Braun K.A., Lao Y., He Z., Ingles C.J., Wold M.S. Role of protein-protein interactions in the function of replication protein A (RPA): RPA modulates the activity of DNA polymerase alpha by multiple mechanisms. Biochemistry. 36:1997;8443-8454.
    • (1997) Biochemistry , vol.36 , pp. 8443-8454
    • Braun, K.A.1    Lao, Y.2    He, Z.3    Ingles, C.J.4    Wold, M.S.5
  • 13
    • 0027299244 scopus 로고
    • The transactivator proteins VP16 and GAL4 bind replication factor a
    • He Z., Brinton B.T., Greenblatt J., Hassell J.A., Ingles C.J. The transactivator proteins VP16 and GAL4 bind replication factor A. Cell. 73:1993;1223-1232.
    • (1993) Cell , vol.73 , pp. 1223-1232
    • He, Z.1    Brinton, B.T.2    Greenblatt, J.3    Hassell, J.A.4    Ingles, C.J.5
  • 14
    • 0030054869 scopus 로고    scopus 로고
    • Dissection of functional domains of the human DNA replication protein complex replication protein a
    • Lin Y.L., Chen C., Keshav K.F., Winchester E., Dutta A. Dissection of functional domains of the human DNA replication protein complex replication protein A. J. Biol. Chem. 271:1996;17190-17198.
    • (1996) J. Biol. Chem. , vol.271 , pp. 17190-17198
    • Lin, Y.L.1    Chen, C.2    Keshav, K.F.3    Winchester, E.4    Dutta, A.5
  • 15
    • 0035008609 scopus 로고    scopus 로고
    • Rfc4 interacts with Rpa1 and is required for both DNA replication and DNA damage checkpoints in Saccharomyces cerevisiae
    • Kim H.S., Brill S.J. Rfc4 interacts with Rpa1 and is required for both DNA replication and DNA damage checkpoints in Saccharomyces cerevisiae. Mol. Cell. Biol. 21:2001;3725-3737.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3725-3737
    • Kim, H.S.1    Brill, S.J.2
  • 16
    • 0033230401 scopus 로고    scopus 로고
    • Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme
    • Yuzhakov A., Kelman Z., Hurwitz J., O'Donnell M. Multiple competition reactions for RPA order the assembly of the DNA polymerase delta holoenzyme. EMBO J. 18:1999;6189-6199.
    • (1999) EMBO J. , vol.18 , pp. 6189-6199
    • Yuzhakov, A.1    Kelman, Z.2    Hurwitz, J.3    O'Donnell, M.4
  • 17
    • 0035449355 scopus 로고    scopus 로고
    • Cell cycle checkpoint signaling through the ATM and ATR kinases
    • Abraham R.T. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes Dev. 15:2001;2177-2196.
    • (2001) Genes Dev. , vol.15 , pp. 2177-2196
    • Abraham, R.T.1
  • 18
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim S.T., Lim D.S., Canman C.E., Kastan M.B. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274:1999;37538-37543.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37538-37543
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 19
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez Y., Desany B.A., Jones W.J., Liu Q., Wang B., Elledge S.J. Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science. 271:1996;357-360.
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desany, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 20
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert T.A., Kiser G.L., Hartwell L.H. Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes Dev. 8:1994;652-665.
    • (1994) Genes Dev. , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 21
    • 0034881760 scopus 로고    scopus 로고
    • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
    • Gilbert C.S., Green C.M., Lowndes N.F. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol. Cell. 8:2001;129-136.
    • (2001) Mol. Cell , vol.8 , pp. 129-136
    • Gilbert, C.S.1    Green, C.M.2    Lowndes, N.F.3
  • 22
    • 0033570894 scopus 로고    scopus 로고
    • Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase
    • Pellicioli A., Lucca C., Liberi G., Marini F., Lopes M., Plevani P., Romano A., Di Fiore P.P., Foiani M. Activation of Rad53 kinase in response to DNA damage and its effect in modulating phosphorylation of the lagging strand DNA polymerase. EMBO J. 18:1999;6561-6572.
    • (1999) EMBO J. , vol.18 , pp. 6561-6572
    • Pellicioli, A.1    Lucca, C.2    Liberi, G.3    Marini, F.4    Lopes, M.5    Plevani, P.6    Romano, A.7    Di Fiore, P.P.8    Foiani, M.9
  • 23
    • 0027968012 scopus 로고
    • The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast
    • Allen J.B., Zhou Z., Siede W., Friedberg E.C., Elledge S.J. The SAD1/RAD53 protein kinase controls multiple checkpoints and DNA damage-induced transcription in yeast. Genes Dev. 8:1994;2401-2415.
    • (1994) Genes Dev. , vol.8 , pp. 2401-2415
    • Allen, J.B.1    Zhou, Z.2    Siede, W.3    Friedberg, E.C.4    Elledge, S.J.5
  • 24
    • 0025365192 scopus 로고
    • Cell-cycle-regulated phosphorylation of DNA replication factor a from human and yeast cells
    • Din S., Brill S., Fairman M.P., Stillman B. Cell-cycle-regulated phosphorylation of DNA replication factor A from human and yeast cells. Genes Dev. 4:1990;968-977.
    • (1990) Genes Dev. , vol.4 , pp. 968-977
    • Din, S.1    Brill, S.2    Fairman, M.P.3    Stillman, B.4
  • 25
    • 0028607553 scopus 로고
    • The DNA-activated protein kinase is required for the phosphorylation of replication protein a during simian virus 40 DNA replication
    • Brush G.S., Anderson C.W., Kelly T.J. The DNA-activated protein kinase is required for the phosphorylation of replication protein A during simian virus 40 DNA replication. Proc. Natl. Acad. Sci. U.S.A. 91:1994;12520-12524.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 12520-12524
    • Brush, G.S.1    Anderson, C.W.2    Kelly, T.J.3
  • 26
    • 0028016304 scopus 로고
    • Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin a complex and DNA-dependent protein kinase
    • Pan Z.Q., Amin A.A., Gibbs E., Niu H., Hurwitz J. Phosphorylation of the p34 subunit of human single-stranded-DNA-binding protein in cyclin A-activated G1 extracts is catalyzed by cdk-cyclin A complex and DNA-dependent protein kinase. Proc. Natl. Acad. Sci. U.S.A. 91:1994;8343-8347.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 8343-8347
    • Pan, Z.Q.1    Amin, A.A.2    Gibbs, E.3    Niu, H.4    Hurwitz, J.5
  • 27
    • 0027428513 scopus 로고
    • The ionizing radiation-induced replication protein a phosphorylation response differs between ataxia telangiectasia and normal human cells
    • Liu V.F., Weaver D.T. The ionizing radiation-induced replication protein A phosphorylation response differs between ataxia telangiectasia and normal human cells. Mol. Cell. Biol. 13:1993;7222-7231.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 7222-7231
    • Liu, V.F.1    Weaver, D.T.2
  • 28
    • 0028355488 scopus 로고
    • UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein
    • Carty M.P., Zernik-Kobak M., McGrath S., Dixon K. UV light-induced DNA synthesis arrest in HeLa cells is associated with changes in phosphorylation of human single-stranded DNA-binding protein. EMBO J. 13:1994;2114-2123.
    • (1994) EMBO J. , vol.13 , pp. 2114-2123
    • Carty, M.P.1    Zernik-Kobak, M.2    McGrath, S.3    Dixon, K.4
  • 29
    • 0037106186 scopus 로고    scopus 로고
    • A requirement for replication in activation of the ATR-dependent DNA damage checkpoint
    • Lupardus P.J., Byun T., Yee M.C., Hekmat-Nejad M., Cimprich K.A. A requirement for replication in activation of the ATR-dependent DNA damage checkpoint. Genes Dev. 16:2002;2327-2332.
    • (2002) Genes Dev. , vol.16 , pp. 2327-2332
    • Lupardus, P.J.1    Byun, T.2    Yee, M.C.3    Hekmat-Nejad, M.4    Cimprich, K.A.5
  • 30
    • 0035577796 scopus 로고    scopus 로고
    • Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase
    • Wang H., Guan J., Perrault A.R., Wang Y., Iliakis G. Replication protein A2 phosphorylation after DNA damage by the coordinated action of ataxia telangiectasia-mutated and DNA-dependent protein kinase. Cancer Res. 61:2001;8554-8563.
    • (2001) Cancer Res. , vol.61 , pp. 8554-8563
    • Wang, H.1    Guan, J.2    Perrault, A.R.3    Wang, Y.4    Iliakis, G.5
  • 32
    • 0242417571 scopus 로고    scopus 로고
    • RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions
    • Oakley G.G., Patrick S.M., Yao J., Carty M.P., Turchi J.J., Dixon K. RPA phosphorylation in mitosis alters DNA binding and protein-protein interactions. Biochemistry. 42:2003;3255-3264.
    • (2003) Biochemistry , vol.42 , pp. 3255-3264
    • Oakley, G.G.1    Patrick, S.M.2    Yao, J.3    Carty, M.P.4    Turchi, J.J.5    Dixon, K.6
  • 33
    • 0030479885 scopus 로고    scopus 로고
    • The ATM homologue MEC1 is required for phosphorylation of replication protein a in yeast
    • Brush G.S., Morrow D.M., Hieter P., Kelly T.J. The ATM homologue MEC1 is required for phosphorylation of replication protein A in yeast. Proc. Natl. Acad. Sci. U.S.A. 93:1996;15075-15080.
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , pp. 15075-15080
    • Brush, G.S.1    Morrow, D.M.2    Hieter, P.3    Kelly, T.J.4
  • 34
    • 0034307720 scopus 로고    scopus 로고
    • Phosphorylation of the replication protein a large subunit in the Saccharomyces cerevisiae checkpoint response
    • Brush G.S., Kelly T.J. Phosphorylation of the replication protein A large subunit in the Saccharomyces cerevisiae checkpoint response. Nucleic Acids Res. 28:2000;3725-3732.
    • (2000) Nucleic Acids Res. , vol.28 , pp. 3725-3732
    • Brush, G.S.1    Kelly, T.J.2
  • 35
    • 0029791693 scopus 로고    scopus 로고
    • The 70 kDa subunit of replication protein a is required for the G1/S and intra-S DNA damage checkpoints in budding yeast
    • Longhese M.P., Neecke H., Paciotti V., Lucchini G., Plevani P. The 70 kDa subunit of replication protein A is required for the G1/S and intra-S DNA damage checkpoints in budding yeast. Nucleic Acids Res. 24:1996;3533-3537.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 3533-3537
    • Longhese, M.P.1    Neecke, H.2    Paciotti, V.3    Lucchini, G.4    Plevani, P.5
  • 36
    • 0032167423 scopus 로고    scopus 로고
    • Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases
    • Tanaka T., Nasmyth K. Association of RPA with chromosomal replication origins requires an Mcm protein, and is regulated by Rad53, and cyclin- and Dbf4-dependent kinases. EMBO J. 17:1998;5182-5191.
    • (1998) EMBO J. , vol.17 , pp. 5182-5191
    • Tanaka, T.1    Nasmyth, K.2
  • 37
    • 0024977417 scopus 로고
    • Elevated recombination rates in transcriptionally active DNA
    • Thomas B.J., Rothstein R. Elevated recombination rates in transcriptionally active DNA. Cell. 56:1989;619-630.
    • (1989) Cell , vol.56 , pp. 619-630
    • Thomas, B.J.1    Rothstein, R.2
  • 38
    • 0034610290 scopus 로고    scopus 로고
    • Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase
    • Mallory J.C., Petes T.D. Protein kinase activity of Tel1p and Mec1p, two Saccharomyces cerevisiae proteins related to the human ATM protein kinase. Proc. Natl. Acad. Sci. U.S.A. 97:2000;13749-13754.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 13749-13754
    • Mallory, J.C.1    Petes, T.D.2
  • 40
    • 0032512745 scopus 로고    scopus 로고
    • The RPA32 subunit of human replication protein a contains a single-stranded DNA-binding domain
    • Bochkareva E., Frappier L., Edwards A.M., Bochkarev A. The RPA32 subunit of human replication protein A contains a single-stranded DNA-binding domain. J. Biol. Chem. 273:1998;3932-3936.
    • (1998) J. Biol. Chem. , vol.273 , pp. 3932-3936
    • Bochkareva, E.1    Frappier, L.2    Edwards, A.M.3    Bochkarev, A.4
  • 42
    • 0036241880 scopus 로고    scopus 로고
    • Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo
    • Rouse J., Jackson S.P. Lcd1p recruits Mec1p to DNA lesions in vitro and in vivo. Mol. Cell. 9:2002;857-869.
    • (2002) Mol. Cell , vol.9 , pp. 857-869
    • Rouse, J.1    Jackson, S.P.2
  • 43
    • 0035019655 scopus 로고    scopus 로고
    • Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway
    • Paciotti V., Clerici M., Scotti M., Lucchini G., Longhese M.P. Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway. Mol. Cell. Biol. 21:2001;3913-3925.
    • (2001) Mol. Cell. Biol. , vol.21 , pp. 3913-3925
    • Paciotti, V.1    Clerici, M.2    Scotti, M.3    Lucchini, G.4    Longhese, M.P.5
  • 44
    • 0026651978 scopus 로고
    • Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations
    • Lai J.S., Herr W. Ethidium bromide provides a simple tool for identifying genuine DNA-independent protein associations. Proc. Natl. Acad. Sci. U.S.A. 89:1992;6958-6962.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 6958-6962
    • Lai, J.S.1    Herr, W.2
  • 45
    • 0028882869 scopus 로고
    • Yeast checkpoint genes in DNA damage processing: Implications for repair and arrest
    • Lydall D., Weinert T. Yeast checkpoint genes in DNA damage processing: implications for repair and arrest. Science. 270:1995;1488-1491.
    • (1995) Science , vol.270 , pp. 1488-1491
    • Lydall, D.1    Weinert, T.2
  • 46
    • 0032493889 scopus 로고    scopus 로고
    • Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage
    • Lee S.E., Moore J.K., Holmes A., Umezu K., Kolodner R.D., Haber J.E. Saccharomyces Ku70, mre11/rad50 and RPA proteins regulate adaptation to G2/M arrest after DNA damage. Cell. 94:1998;399-409.
    • (1998) Cell , vol.94 , pp. 399-409
    • Lee, S.E.1    Moore, J.K.2    Holmes, A.3    Umezu, K.4    Kolodner, R.D.5    Haber, J.E.6
  • 47
    • 0035498938 scopus 로고    scopus 로고
    • Two checkpoint complexes are independently recruited to sites of DNA damage in vivo
    • Melo J.A., Cohen J., Toczyski D.P. Two checkpoint complexes are independently recruited to sites of DNA damage in vivo. Genes Dev. 15:2001;2809-2821.
    • (2001) Genes Dev. , vol.15 , pp. 2809-2821
    • Melo, J.A.1    Cohen, J.2    Toczyski, D.P.3
  • 48
    • 0037567268 scopus 로고    scopus 로고
    • Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes
    • Zou L., Elledge S.J. Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes. Science. 300:2003;1542-1548.
    • (2003) Science , vol.300 , pp. 1542-1548
    • Zou, L.1    Elledge, S.J.2
  • 49
    • 0035697323 scopus 로고    scopus 로고
    • Spontaneous chromosome loss in Saccharomyces cerevisiae is suppressed by DNA damage checkpoint functions
    • Klein H.L. Spontaneous chromosome loss in Saccharomyces cerevisiae is suppressed by DNA damage checkpoint functions. Genetics. 159:2001;1501-1509.
    • (2001) Genetics , vol.159 , pp. 1501-1509
    • Klein, H.L.1
  • 50
    • 0035830498 scopus 로고    scopus 로고
    • Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae
    • Myung K., Datta A., Kolodner R.D. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell. 104:2001;397-408.
    • (2001) Cell , vol.104 , pp. 397-408
    • Myung, K.1    Datta, A.2    Kolodner, R.D.3
  • 51
    • 0037178723 scopus 로고    scopus 로고
    • ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones
    • Cha R.S., Kleckner N. ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones. Science. 297:2002;602-606.
    • (2002) Science , vol.297 , pp. 602-606
    • Cha, R.S.1    Kleckner, N.2
  • 52
    • 0032527776 scopus 로고    scopus 로고
    • Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p
    • Paciotti V., Lucchini G., Plevani P., Longhese M.P. Mec1p is essential for phosphorylation of the yeast DNA damage checkpoint protein Ddc1p, which physically interacts with Mec3p. EMBO J. 17:1998;4199-4209.
    • (1998) EMBO J. , vol.17 , pp. 4199-4209
    • Paciotti, V.1    Lucchini, G.2    Plevani, P.3    Longhese, M.P.4
  • 53
    • 0028859923 scopus 로고
    • Cell cycle-dependent phosphorylation and dephosphorylation of the yeast DNA polymerase alpha-primase B subunit
    • Foiani M., Liberi G., Lucchini G., Plevani P. Cell cycle-dependent phosphorylation and dephosphorylation of the yeast DNA polymerase alpha-primase B subunit. Mol. Cell. Biol. 15:1995;883-891.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 883-891
    • Foiani, M.1    Liberi, G.2    Lucchini, G.3    Plevani, P.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.