A comparison of the effects of medium- and long-chain triglycerides on neutrophil stimulation in experimental ileitis

Journal of Gastroenterology

Volumn 38, Issue 2, 2003, Pages 127-133

  Ohta, Noriyasu ^a   Tsujikawa, Tomoyuki ^b   Nakamura, Tsuyoshi ^a   Andoh, Akira ^b   Sasaki, Masaya ^b   Bamba, Tadao ^b  

^a SNOW BRAND MILK PRODUCTS CO LTD   (Japan)

^b SHIGA UNIVERSITY OF MEDICAL SCIENCE   (Japan)

Author keywords

Ileitis; Neutrophils; Triglycerides; Trinitrobenzene sulfonic acid

Indexed keywords

ANESTHETIC AGENT; CD11B ANTIGEN; CORN OIL; DEXTRIN; INTERLEUKIN 8; LONG CHAIN TRIACYLGLYCEROL; MEDIUM CHAIN TRIACYLGLYCEROL; MYELOPEROXIDASE; PENTOBARBITAL; TRINITROBENZENESULFONIC ACID; TRIOCTANOIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVITY; FAT INTAKE; FEEDING; ILEITIS; ILEUM; IMMUNE RESPONSE; INTESTINE INJURY; LEUKOCYTE ACTIVATION; MALE; MORPHOLOGY; NEUTROPHIL; NONHUMAN; PRIORITY JOURNAL; RAT; RAT STRAIN; STATISTICAL SIGNIFICANCE; STRUCTURE ACTIVITY RELATION; TIME;

ANIMALS; ANTIGENS, CD11B; DIETARY FATS; ILEITIS; MALE; NEUTROPHILS; RATS; RATS, SPRAGUE-DAWLEY; TRIGLYCERIDES;

EID: 0345268649     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350300021     Document Type: Article

References (28)

1. Reif S, Klein I, Lubin F, Farbstein M, Hallak A, Gilat T. Pre-illness dietary factors in inflammatory bowel disease. Gut 1997;40:754-60.
2. Teahon K, Bjarnason I, Pearson M, Levi AJ. Ten years' experience with an elemental diet in the management of Crohn's disease. Gut 1990;31:1133-7.
3. O'Morain C, Segal AW, Levi AJ. Elemental diet as primary treatment of acute Crohn's disease. BMJ 1984;288:1859-62.
4. Fernandez-Banares F, Cabre E, Gonzalez-Huix F, Gassull MA. Enteral nutrition as primary therapy in Crohn's disease. Gut 1994;1 (Suppl):55-9.
5. Middleton SJ, Rucker JT, Kirby GA, Riordan AM, Hunter JO. Long-chain triglycerides reduce the efficacy of enteral feeds in patients with active Crohn's disease. Clin Nutr 1995;14:229-36.
6. Khoshoo V, Reifen R, Neuman MG, Griffiths A, Pencharz PB. Effect of low- and high-fat, peptide-based diets on body composition and disease activity in adolescents with active Crohn's disease. JPEN J Parenter Enteral Nutr 1996;20:401-5.
7. Polk DB, Hattner AT, Kerner JA. Improved growth and disease activity after intermittent administration of a defined formula diet in children with Crohn's disease. JPEN J Parenter Enteral Nutr 1992;16:499-504.
8. Shoda R, Matueda K, Yamato S, Umeda N. Therapeutic efficacy of n-3 polyunsaturated fatty acid in experimental Crohn's disease. J Gastroenterol 1995;30 (Suppl):98-101.
9. Vilaseca J, Salas A, Guarner F, Rodriguez R, Martinez M, Malagelada JR. Dietary fish oil reduces progression of chronic inflammatory lesions in a rat model of granulomatous colitis. Gut 1990;31:539-44.
10. Tsujikawa T, Ohta N, Nakamura T, Satoh J, Uda K, Ihara T, et al. Medium-chain triglycerides modulate ileitis induced by trinitro-benzene sulfonic acid. J Gastroenterol Hepatol 1999;14:1166-72.
11. Neil MB, Granger D. Mechanisms of neutrophil-mediated tissue injury. In: MacDermott RP, Stenson WF, editors. Inflammatory bowel disease. New York: Elsevier Science; 1992. p.225-39.
12. Mukaida N, Harada A, Matsushima K. Interleukin-8 (IL-8) and monocyte chemotactic and activating factor (MCAF/MCP-1), chemokines essentially involved in inflammatory and immune reactions. Cytokine Growth Factor Rev 1998;9:9-23.
13. Parkos CA, Colgan SP, Diamond MS, Nusrat A, Liang TW, Springer TA, et al. Expression and polarization of intercellular adhesion molecule-1 on human intestinal epithelia: consequences for CD11/CD18-mediated interactions with neutrophils. Mol Med 1996;2:489-505.
14. Henderson RB, Lim LHK, Tessier PA, Gavins FNE, Mathies M, Perretti M, et al. The use of lymphocyte function-associated antigen (LFA)-1-deficient mice to determine the role of LFA-1, Mac-1, and α4 integrin in the inflammatory response of neutrophils. J Exp Med 2001;194:219-26.
15. Miller MJ, Sadawska-Krowcka H, Chotinaruemol S, Kakkis JL, Clark DA. Amelioration of chronic ileitis by nitric oxide synthase inhibition. J Pharmacol Exp Ther 1993;264:11-6.
16. Krawisz JE, Sharon P, Stenson WF. Quantitative assay for acute intestinal inflammation based on myeloperoxidase activity. Gastroenterology 1984;87:1344-50.
17. Bozic CR, Kolakowski LF, Gerard NP, Garcia-Rodriguez C, Uexkull-Guldenband C, Conklyn MJ, et al. Expression and biologic characterization of the murine chemokine KC. J Immunol 1995;154:6048-57.
18. Shoda R, Matsueda K, Yamamoto S, Umeda N. Epidemiologic analysis of Crohn disease in Japan: increased dietary intake of n-6 polyunsaturated fatty acids and animal protein relates to the increased incidence of Crohn disease in Japan. Am J Clin Nutr 1996;63:741-5.
19. Belluzzi A, Brignola C, Campieri M, Pera A, Boschi S, Miglioli M. Effect of an enteric-coated fish-oil preparation on relapses in Crohn's disease. N Engl J Med 1996;334:1557-60.
20. Mitsuyama K, Toyonaga A, Sasaki E, Watanabe K, Tateishi H, Nishiyama T, et al. IL-8 as an important chemoattractant for neutrophils in ulcerative colitis and Crohn's disease. Clin Exp Immunol 1994;96:432-6.
21. MacDermott RP, Sanderson IR, Reinecker HC. The central role of chemokines (chemotactic cytokines) in the immunopathogenesis of ulcerative colitis and Crohn's disease. Inflamm Bowel Dis 1998;4:54-67.
22. Sanderson IR, Udeen S, Davies PSW, Savage MO, Walker-Smith JA. Remission induced by an elemental diet in small bowel Crohn's disease. Arch Dis Child 1987;62:123-7.
23. Andoh A, Takaya H, Araki Y, Tsujikawa T, Fujiyama Y, Bamba T. Medium- and long-chain fatty acids differentially modulate interleukine-8 secretion in human fetal intestinal epithelial cells. J Nutr 2000;130:2636-40.
24. Kono H, Enomoto N, Connor HD, Wheeler MD, Bradford BU, Rivera CA, et al. Medium-chain triglycerides inhibit free radical formation and TNF-α production in rats given enteral ethanol. Am J Physiol Gastrointest Liver Physiol 2000;278:G467-76.
25. Springer TA. Traffic signals for lymphocyte recirculation and leukocyte emigration: the multistep paradigm. Cell 1994;76:301-14.
26. Li Y, Ferrante A, Poulos A, Harvey DP. Neutrophil oxygen radical generation. J Clin Invest 1996;97:1605-9.
27. Burch RM, Noronha-Blob L, Bator JM, Lowe VC, Sullivan JP. Mice treated with a leumedin or antibody to Mac-1 to inhibit leukocyte sequestration survive endotoxin challenge. J Immunol 1993;150:3397-403.
28. Morris GP, Beck PL, Herridge MS, Depew WT, Szewczuk R, Wallace JL. Hapten-induced model of chronic inflammation and ulceration in the rat colon. Gastroenterology 1989;96:795-803.