Rescue of mutants of the tumor suppressor p53 in cancer cells by a designed peptide

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 23, 2003, Pages 13303-13307

  Issaeva, Natalia ^a   Friedler, Assaf ^b   Bozko, Przemyslaw ^a   Wiman, Klas G ^a   Fersht, Alan R ^b   Selivanova, Galina ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ALANYLGLUTAMYLASPARTYLGLUTAMYLASPARTYLGLUTAMYLISOLEUCYLGLUTAMYLTRYPTOPHAN; ARGINYLALANYLASPARTYLALANYLASPARTYLALANYLISOLEUCYLALANYLTRYPTOPHAN; ARGINYLGLUTAMYLASPARTYLGLUTAMYLASPARTYLGLUTAMYLISOLEUCYLGLUTAMYLTRYPTOPHAN; ARGINYLLYSYLSERYLLYSYLLYSYLLYSYLISOLEUCYLTHREONYLTRYPTOPHAN; BIOTIN; CHAPERONE; FLUORESCEIN; HISTIDINE; MUTANT PROTEIN; PEPTIDE DERIVATIVE; PROTEIN P53; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CANCER INHIBITION; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; DENATURATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN EXPRESSION; PROTEIN INDUCTION; PROTEIN TARGETING; PROTEIN TRANSPORT; UPREGULATION; WILD TYPE;

APOPTOSIS; CELL LINE, TUMOR; CELL NUCLEUS; CELL SEPARATION; CYTOPLASM; EPITOPES; FLOW CYTOMETRY; FLUORESCEINS; FLUORESCENT DYES; GAMMA RAYS; HUMANS; KINETICS; MUTATION; OLIGOPEPTIDES; PEPTIDES; PROTEIN CONFORMATION; TIME FACTORS; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION, GENETIC; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 0345255605     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.1835733100     Document Type: Article

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