Degradation of β-Amyloid by Proteolytic Antibody Light Chains

Biochemistry

Volumn 42, Issue 48, 2003, Pages 14328-14334

  Rangan, Srinath Kasturi ^a   Liu, Ruitian ^a   Brune, Daniel ^b   Planque, Stephanie ^c   Paul, Sudhir ^c   Sierks, Michael R ^a,d  

^a Arizona State University   (United States)

^b ARIZONA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^d Chemical and Materials Engineering   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; ANTIBODIES; DEGRADATION; DISEASES; ENZYMES; HYDROLYSIS; MASS SPECTROMETRY;

ANTIBODY LIGHT CHAINS; PATHOGENESIS;

BIOCHEMISTRY;

ALPHA SECRETASE; AMINO ACID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 28); AMYLOID BETA-PROTEIN (1-28); AMYLOID PRECURSOR PROTEIN; BENZYLOXYCARBONYLLYSINE 2 NITROPHENYL ESTER; CARBOXYPEPTIDASE; CHROMOGENIC SUBSTRATE; DRUG DERIVATIVE; ESTER DERIVATIVE; IMMUNOGLOBULIN FRAGMENT; IMMUNOGLOBULIN FV; IMMUNOGLOBULIN LIGHT CHAIN; IMMUNOGLOBULIN LIGHT CHAIN ANTIBODY; LEUCINE; LYSINE; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY C23.5; MONOCLONAL ANTIBODY HK14; N BENZYLOXYCARBONYLLYSINE 4 NITROPHENYL ESTER; N-BENZYLOXYCARBONYLLYSINE 4-NITROPHENYL ESTER; PEPTIDE FRAGMENT; PROTEIN ANTIBODY; PROTEINASE; RECOMBINANT ANTIBODY; SECRETASE; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL; ARTICLE; BIOACCUMULATION; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CHEMICAL BOND; CONTROLLED STUDY; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME SPECIFICITY; ENZYME SUBSTRATE; HUMAN; HYDROLYSIS; IMMUNOLOGY; KINETICS; MASS SPECTROMETRY; METABOLISM; MOUSE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEIN ENGINEERING; PROTEIN FUNCTION; PROTEIN HYDROLYSIS; PROTEIN METABOLISM; PROTEIN STRUCTURE; VACCINATION;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ANTIBODIES, MONOCLONAL; ASPARTIC ENDOPEPTIDASES; CARBOXYPEPTIDASES; CATALYSIS; CHROMOGENIC COMPOUNDS; ENDOPEPTIDASES; HUMANS; HYDROLYSIS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULIN LIGHT CHAINS; KINETICS; LYSINE; MASS SPECTROMETRY; MICE; PEPTIDE FRAGMENTS; SUBSTRATE SPECIFICITY;

ANIMALIA;

EID: 0345060484     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi035038d     Document Type: Article

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