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Volumn 6, Issue 9, 1999, Pages 873-882

The activity of the murine Bax promoter is regulated by Sp1/3 and E-box binding proteins but not by p53

Author keywords

Apoptosis; Bax; In vivo footprinting; p53

Indexed keywords

DNA BINDING PROTEIN; MESSENGER RNA; PROTEIN BAX; PROTEIN P53; TRANSCRIPTION FACTOR SP1;

EID: 0344980250     PISSN: 13509047     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cdd.4400562     Document Type: Article
Times cited : (45)

References (38)
  • 1
    • 0030916669 scopus 로고    scopus 로고
    • The proto-oncogene Bcl-2 and its role in regulating apoptosis
    • Kroemer G (1997) The proto-oncogene Bcl-2 and its role in regulating apoptosis. Nature Med. 3: 614-620
    • (1997) Nature Med. , vol.3 , pp. 614-620
    • Kroemer, G.1
  • 2
    • 0030459311 scopus 로고    scopus 로고
    • Regulators of life and death: The bcl-2 gene family
    • Möröy T and Zörnig M (1997) Regulators of life and death: the bcl-2 gene family. J. Cell Phys. Biochem. 6: 312-336
    • (1997) J. Cell Phys. Biochem. , vol.6 , pp. 312-336
    • Möröy, T.1    Zörnig, M.2
  • 3
    • 0030979773 scopus 로고    scopus 로고
    • Double identity for proteins of the Bcl-2 family
    • Reed JC (1997) Double identity for proteins of the Bcl-2 family. Nature 387: 773-776
    • (1997) Nature , vol.387 , pp. 773-776
    • Reed, J.C.1
  • 4
    • 0030665659 scopus 로고    scopus 로고
    • The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumorigenesis and resistance to chemotherapy
    • Strasser A, Huang D and Vaux DL (1997) The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumorigenesis and resistance to chemotherapy. Biochim. Biophys. Acta 1333: F151-F178
    • (1997) Biochim. Biophys. Acta , vol.1333
    • Strasser, A.1    Huang, D.2    Vaux, D.L.3
  • 5
    • 0029671112 scopus 로고    scopus 로고
    • Gamma radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo
    • Kitada S, Krajewski S, Myashita T, Krajewska M and Reed JC (1996) Gamma radiation induces upregulation of Bax protein and apoptosis in radiosensitive cells in vivo. Oncogene 12: 187-192
    • (1996) Oncogene , vol.12 , pp. 187-192
    • Kitada, S.1    Krajewski, S.2    Myashita, T.3    Krajewska, M.4    Reed, J.C.5
  • 6
    • 0028883179 scopus 로고
    • Tumor suppressor p53 is a direct transcriptional activator of the human bax gene
    • Miyashita T and Reed JC (1995) Tumor suppressor p53 is a direct transcriptional activator of the human bax gene. Cell 80: 293-299
    • (1995) Cell , vol.80 , pp. 293-299
    • Miyashita, T.1    Reed, J.C.2
  • 8
    • 0030449990 scopus 로고    scopus 로고
    • Bax alpha perturbs T cell development and affects cell cycle entry of T cells
    • Brady HJ, Gil-Gomez G, Kirberg J and Berns AJ (1996) Bax alpha perturbs T cell development and affects cell cycle entry of T cells. EMBO J. 15: 6991-7001
    • (1996) EMBO J. , vol.15 , pp. 6991-7001
    • Brady, H.J.1    Gil-Gomez, G.2    Kirberg, J.3    Berns, A.J.4
  • 9
    • 0029669929 scopus 로고    scopus 로고
    • T cells from bax alpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53
    • Brady HJ, Salomons GS, Bobeldijk RC and Berns AJ (1996) T cells from bax alpha transgenic mice show accelerated apoptosis in response to stimuli but do not show restored DNA damage-induced cell death in the absence of p53. EMBO J. 15: 1221-1230
    • (1996) EMBO J. , vol.15 , pp. 1221-1230
    • Brady, H.J.1    Salomons, G.S.2    Bobeldijk, R.C.3    Berns, A.J.4
  • 10
    • 0029802591 scopus 로고    scopus 로고
    • p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells
    • Chen X, Ko LJ, Jayaraman L and Prives C (1996) p53 levels, functional domains, and DNA damage determine the extent of the apoptotic response of tumor cells. Genes Dev. 10: 2438-2451
    • (1996) Genes Dev. , vol.10 , pp. 2438-2451
    • Chen, X.1    Ko, L.J.2    Jayaraman, L.3    Prives, C.4
  • 11
    • 0030265337 scopus 로고    scopus 로고
    • The p53-deficient mouse: A model for basic and applied cancer
    • Donehower LA (1996) The p53-deficient mouse: a model for basic and applied cancer. Semin. Cancer Biol. 7: 269-278
    • (1996) Semin. Cancer Biol. , vol.7 , pp. 269-278
    • Donehower, L.A.1
  • 12
    • 0029980043 scopus 로고    scopus 로고
    • p53 in growth control and neoplasia
    • Gottlieb E and Oren M (1996) p53 in growth control and neoplasia. Biochem. Biophys. Acta 1287: 77-102
    • (1996) Biochem. Biophys. Acta , vol.1287 , pp. 77-102
    • Gottlieb, E.1    Oren, M.2
  • 13
    • 0029972806 scopus 로고    scopus 로고
    • p53: Puzzle and paradigm
    • Ko LJ and Prives C (1996) p53: puzzle and paradigm. Genes & Dev. 10: 1054-1072
    • (1996) Genes & Dev. , vol.10 , pp. 1054-1072
    • Ko, L.J.1    Prives, C.2
  • 14
    • 0027326586 scopus 로고
    • The tumor suppressor genes
    • Levine A (1993) The tumor suppressor genes. Ann. Rev. Biochem. 62: 623-651
    • (1993) Ann. Rev. Biochem. , vol.62 , pp. 623-651
    • Levine, A.1
  • 16
    • 0027496935 scopus 로고
    • The p21 CDK-interacting protein Cip1 is a potent inhibitor of G1 cyclin dependent kinases
    • Harper JW, Adami GR, Wie N, Keyomarsi K and Elledge SJ (1993)The p21 CDK-interacting protein Cip1 is a potent inhibitor of G1 cyclin dependent kinases. Cell 75: 805-816
    • (1993) Cell , vol.75 , pp. 805-816
    • Harper, J.W.1    Adami, G.R.2    Wie, N.3    Keyomarsi, K.4    Elledge, S.J.5
  • 18
    • 0030013337 scopus 로고    scopus 로고
    • Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis
    • Attardi LD, Lowe SW, Brugarolas J and Jacks T (1996) Transcriptional activation by p53, but not induction of the p21 gene, is essential for oncogene-mediated apoptosis. EMBO J. 15: 3693-3701
    • (1996) EMBO J. , vol.15 , pp. 3693-3701
    • Attardi, L.D.1    Lowe, S.W.2    Brugarolas, J.3    Jacks, T.4
  • 22
    • 0029018215 scopus 로고
    • Members of the Sp transcription factor family control transcription from the uteroglobin promoter
    • Dennig J, Hagen G, Beato M and Suske G (1995)Members of the Sp transcription factor family control transcription from the uteroglobin promoter. J. Biol. Chem. 270: 12737-12744
    • (1995) J. Biol. Chem. , vol.270 , pp. 12737-12744
    • Dennig, J.1    Hagen, G.2    Beato, M.3    Suske, G.4
  • 23
    • 0029864934 scopus 로고    scopus 로고
    • Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc
    • Desbarats L, Gaubatz S and Eilers M (1996) Discrimination between different E-box-binding proteins at an endogenous target gene of c-myc. Genes Dev. 10: 447-460
    • (1996) Genes Dev. , vol.10 , pp. 447-460
    • Desbarats, L.1    Gaubatz, S.2    Eilers, M.3
  • 24
    • 0031038137 scopus 로고    scopus 로고
    • Bax suppresses tumorigenesis and stimulates apoptosis in vivo
    • Yin C, Knudson CM, Korsmeyer SJ and Van Dyke T (1997) Bax suppresses tumorigenesis and stimulates apoptosis in vivo. Nature 385: 637-640
    • (1997) Nature , vol.385 , pp. 637-640
    • Yin, C.1    Knudson, C.M.2    Korsmeyer, S.J.3    Van Dyke, T.4
  • 25
    • 0030938089 scopus 로고    scopus 로고
    • Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis
    • McCurrach ME, Connor TMF, Knudson CM, Korsmeyer SJ and Lowe SW (1997) Bax-deficiency promotes drug resistance and oncogenic transformation by attenuating p53-dependent apoptosis. Proc. Natl. Acad. Sci. USA 94: 2345-2349
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 2345-2349
    • McCurrach, M.E.1    Connor, T.M.F.2    Knudson, C.M.3    Korsmeyer, S.J.4    Lowe, S.W.5
  • 26
    • 0029131447 scopus 로고
    • A functional p53-responsive intronic promoter is contained within the human mdm2 gene
    • Zauberman A, Flusberg D, Haupt Y, Barak Y and Oren M (1995) A functional p53-responsive intronic promoter is contained within the human mdm2 gene. Nuc. Acids Res. 23: 2584-2592
    • (1995) Nuc. Acids Res. , vol.23 , pp. 2584-2592
    • Zauberman, A.1    Flusberg, D.2    Haupt, Y.3    Barak, Y.4    Oren, M.5
  • 27
    • 0032585637 scopus 로고    scopus 로고
    • Mutant p53 can provoke apoptosis in p53-deficient Hep3B cells with delayed kinetics relative to wild-type p53
    • Stähler F and Römer K (1998) Mutant p53 can provoke apoptosis in p53-deficient Hep3B cells with delayed kinetics relative to wild-type p53. Oncogene 17: 3507-3512
    • (1998) Oncogene , vol.17 , pp. 3507-3512
    • Stähler, F.1    Römer, K.2
  • 28
    • 0027166048 scopus 로고
    • Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death
    • Oltvai ZN, Milliman CL and Korsmeyer SJ (1993) Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death. Cell 74: 609-619
    • (1993) Cell , vol.74 , pp. 609-619
    • Oltvai, Z.N.1    Milliman, C.L.2    Korsmeyer, S.J.3
  • 30
    • 0027497115 scopus 로고
    • Expression of a pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice
    • Möröy T, Grzeschiczek A, Petzold S and Hartmann KU (1993) Expression of a pim-1 transgene accelerates lymphoproliferation and inhibits apoptosis in lpr/lpr mice. Proc. Natl. Acad. Sci. USA 90: 10734-10738
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 10734-10738
    • Möröy, T.1    Grzeschiczek, A.2    Petzold, S.3    Hartmann, K.U.4
  • 31
    • 0028842083 scopus 로고
    • Periodic cdc25C transcription is mediated by a novel cell cycle-regulated repressor element (CDE)
    • Lucibello FC, Truss M, Zwicker J, Ehlert F, Beato M and Müller R (1995) Periodic cdc25C transcription is mediated by a novel cell cycle-regulated repressor element (CDE). EMBO J. 14: 132-142
    • (1995) EMBO J. , vol.14 , pp. 132-142
    • Lucibello, F.C.1    Truss, M.2    Zwicker, J.3    Ehlert, F.4    Beato, M.5    Müller, R.6
  • 33
    • 0028784235 scopus 로고
    • Multiple proteins interact with the nuclear inhibitory repressor element in the human interleukin-3 promoter
    • Engeland K, Andrews NC and Mathey-Prevot B (1995) Multiple proteins interact with the nuclear inhibitory repressor element in the human interleukin-3 promoter. J. Biol. Chem. 270: 24572-24579
    • (1995) J. Biol. Chem. , vol.270 , pp. 24572-24579
    • Engeland, K.1    Andrews, N.C.2    Mathey-Prevot, B.3
  • 34
    • 0024212067 scopus 로고
    • Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer
    • Frohmann MA, Dush MK and Martin GR (1988) Rapid production of full-length cDNAs from rare transcripts: Amplification using a single gene-specific oligonucleotide primer. Proc. Natl. Acad. Sci. USA 85: 8992-9002
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8992-9002
    • Frohmann, M.A.1    Dush, M.K.2    Martin, G.R.3
  • 36
    • 0027944251 scopus 로고
    • Cyclin G is a transcriptional target of the p53 tumor suppressor protein
    • Okamoto K and Beach D (1994) Cyclin G is a transcriptional target of the p53 tumor suppressor protein. EMBO J. 13: 4816-4822
    • (1994) EMBO J. , vol.13 , pp. 4816-4822
    • Okamoto, K.1    Beach, D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.