Heterogeneous T cell receptor Vβ gene repertoire in murine interstitial nephritis

Kidney International

Volumn 49, Issue 5, 1996, Pages 1222-1230

  Heeger, Peter S ^a   Smoyer, William E ^b   Jones, Monica ^b   Hopper, Suellen ^b   Neilson, Eric G ^b  

^a LOUIS STOKES CLEVELAND VA MEDICAL CENTER   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ANIMAL TISSUE; ANTITUBULAR BASEMENT MEMBRANE DISEASE; ARTICLE; CONTROLLED STUDY; INTERSTITIAL NEPHRITIS; KIDNEY FAILURE; KIDNEY FIBROSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE; T LYMPHOCYTE RECEPTOR GENE;

EID: 0029889464     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.176     Document Type: Article

References (12)

1. ACHA-ORBEA H, STEINMAN L, MCDEVITT HO: T cell receptors in murine autoimmune diseases. Ann Rev Immunol 7:371-405, 1989
2. KUMAR V, KONO D, URBAN J, HOOD L: The T-cell receptor repertoire and autoimmune diseases. Ann Rev Immunol 7:657-682, 1989
3. URBAN JL, KUMAR V, KONO DH, GOMEZ C, HORVATH SJ, CLAYTON J, ANDO DG, SERCARZ EE, HOOD L: Restricted use of T cell receptor V genes in murine autoimmune encephalomyelitis raises possibilities for antibody therapy. Cell 54:577-592, 1988
4. CAPRA J, NATVIG J: Is there V region restriction in autoimmune diseases? The Immunologist 1:1, 1993
5. BELL R, LINDSEY J, SOBEL R, HODGKINSON S, STEINMAN L: Diverse T cell receptor V beta gene usage in the central nervous system in experimental allergic encephalomyelitis. J Immunol 150:4085-4092, 1993
6. OKSENBERG J, PANZARA M, BEGOVICH A, MITCHELL D, ERLICH H, MURRAY R, SHIMONKEVITZ R, SHERRITT M, ROTHBARD J, BERNARD C, STEINMAN L: Selection for T-cell receptor Vβ-Dβ-Jβ gene rearrangements with specificity for a myelin basic protein peptide in brain lesions of multiple sclerosis. Nature (London) 362:68-70, 1993
7. SU X, SRIRAM S: Analysis of TCR V beta gene usage and encephalitogenicity of myelin basic protein peptide p91-103 reactive T cell clones in SJL mice: lack of evidence for V gene hypothesis. Cell Immunol 141:485-495, 1992
8. SUN D, LE J, COLECLOOUGH C: Diverse T cell receptor beta chain usage by rat encephalitogenic T cells reactive to residue 68-88 of myelin basic protein. Eur J Immunol 23:494-498, 1993
9. MATSUOKA M, BERNARD N, CONCEPCION E, GRAVES P, BEN-NUN A, DAVIES T: T-cell receptor V region β-chain gene expression in the autoimmune thyroiditis of non-obese diabetic mice. J Immunol 151: 1691-1701, 1993
10. NAKANO N, KIKUTANI H, NISHIMOTO H, KISHIMOTO T: T cell receptor V gene usage of islet β cell-reactive T cells is not restricted in non-obese diabetic mice. J Exp Med 173:1091-1097, 1991
11. ADAMS S, LEBLANC P, DATTA S: Junctional region sequences of T-cell receptor β-chain genes expressed by pathogenic anti-DNA autoantibody-inducing helper T cells from lupus mice: Possible selection by cationic autoantigens. Proc Natl Acad Sci (USA) 88:11271-11275, 1991
12. HEEGER P, SMOYER W, SAAD T, ALBERT S, KELLY C, NEILSON E: Molecular analysis of the helper T cell response in murine interstitial nephritis: T cells recognizing an immunodominant epitope use multiple TcR Vβ genes with similarities across CDR3. J Clin Invest 94:2084-2092, 1994