Structure-based substitutions for increased solubility of a designed protein

Protein Engineering

Volumn 16, Issue 10, 2003, Pages 739-745

  Mosavi, Leila K ^a   Peng, Zheng Yu ^a  

^a UNIVERSITY OF CONNECTICUT HEALTH CENTER   (United States)

Author keywords

Ankyrin repeat; Arginine substitution; pH dependence of stability; Protein design; Protein solubility

Indexed keywords

ANKYRIN; ARGININE; LEUCINE;

ACIDITY; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; HYDROPHOBICITY; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN PROTEIN INTERACTION; PROTEIN SOLUBILITY; PROTEIN STABILITY; PROTEIN STRUCTURE; SOLUBILITY;

EID: 0344874146     PISSN: 02692139     EISSN: None     Source Type: Journal    
DOI: 10.1093/protein/gzg098     Document Type: Article

References (46)

1. Anderson, D.E., Becktel, W.J. and Dahlquist, F.W. (1990) Biochemistry, 29, 2403-2408.
2. Arakawa, T. and Timasheff, S.N. (1985) Methods Enzymol., 114, 49-77.
3. Baldwin, R.L. (1996) Biophys. J., 71, 2056-2063.
4. Becktel, W.J. and Baase, W.A. (1987) Biopolymers, 26, 619-623.
5. Becktel, W.J. and Schellman, J.A. (1987) Biopolymers, 26, 1859-1877.
6. Bogan, A.A. and Thorn, K.S. (1998) J. Mol. Biol., 280, 1-9.
7. Cacace, M.G., Landau, E.M. and Ramsden, J.J. (1997) Q. Rev. Biophys., 30, 241-277.
8. Chen, G.-q., Choi, I., Ramachandran, B. and Gouaux, J.E. (1994) J. Am. Chem. Soc., 116, 8799-8800.
9. Cunningham, B.C. and Wells, J.A. (1987) Protein Eng., 1, 319-325.
10. Dillon, P.J. and Rosen, C.A. (1990) Biotechniques, 9, 298-300.
11. Doering, D.S. (1992) PhD Thesis, Massachusetts Institute of Technology, Cambridge, MA.
12. Edelhoch, H. (1967) Biochemistry, 6, 1948-1954.
13. Folta-Stogniew, E. and Williams, K.R. (1999) J. Biomol. Technol., 10, 51-63.
14. Kapust, R.B. and Waugh, D.S. (1999) Protein Sci., 8, 1668-1674.
15. Kirk, O., Borchert, T.V. and Fuglsang, C.C. (2002) Curr. Opin. Biotechnol., 13, 345-351.
16. Kochendoerfer, G.G. et al. (2003) Science, 299, 884-887.
17. Kohl, A., Binz, H.K., Forrer, P., Stumpp, M.T., Pluckthun, A. and Grutter, M.G. (2003) Proc. Natl Acad. Sci. USA, 100, 1700-1705.
18. Koradi, R., Billeter, M. and Wuthrich, K. (1996) J. Mol. Graph., 14, 51-55.
19. LaVallie, E.R. and McCoy, J.M. (1995) Curr. Opin. Biotechnol., 6, 501-506.
20. Linderstrom-Lang, K. (1924) C. R. Trav. Lab. Carlsberg, Ser. Chim., 15, 29.
21. Masui, A., Fujiwara, N. and Imanaka, T. (1994) Appl. Environ. Microbiol., 60, 3579-3584.
22. Maxwell, K.L., Mittermaier, A.K., Forman-Kay J.D. and Davidson, A.R. (1999) Protein Sci., 8, 1908-1911.
23. Mosavi, L.K., Minor, D.L., Jr and Peng, Z.Y. (2002a) Proc. Natl Acad. Sci. USA, 99, 16029-16034.
24. Mosavi, L.K., Williams, S. and Peng, Z.Y. (2002b) J. Mol. Biol., 320, 165-170.
25. Pace, C.N. (1986) Methods Enzymol., 131, 266-280.
26. Pace, C.N., Laurents, D.V. and Thomson, J.A. (1990) Biochemistry, 29, 2564-2572.
27. Pace, C.N., Laurents, D.V. and Erickson, R.E. (1992) Biochemistry, 31, 2728-2734.
28. Privalov, P.L. (1989) Annu. Rev. Biophys. Biophys. Chem., 18, 47-69.
29. Prodromou, C. and Pearl, L.H. (1992) Protein Eng., 5, 827-829.
30. Record, M.T., Jr, Zhang, W. and Anderson, C.F. (1998) Adv. Protein Chem., 51, 281-353.
31. Sedgwick, S.G. and Smerdon, S.J. (1999) Trends Biochem. Sci., 24, 311-316.
32. Shaw, K.L., Grimsley, G.R., Yakovlev, G.I., Makarov, A.A. and Pace, C.N. (2001) Protein Sci., 10, 1206-1215.
33. Shirai, T., Suzuki, A., Yamane, T., Ashida, T., Kobayashi, T., Hitomi, J. and Ito, S. (1997) Protein Eng., 10, 627-634.
34. Shiraki, K., Kudou, M., Fujiwara, S., Imanaka, T. and Takagi, M. (2002) J. Biochem. (Tokyo), 132, 591-595.
35. Shirley, B.A. (1995) Methods Mol. Biol., 40, 177-190.
36. Staley, J.P. and Kim, P.S. (1994) Protein Sci., 3, 1822-1832.
37. Studier, F.W., Rosenberg, A.H., Dunn, J.J. and Dubendorff, J.W. (1990) Methods Enzymol., 185, 60-89.
38. Turunen, O., Vuorio, M., Fenel, F. and Leisola, M. (2002) Protein Eng., 15, 141-145.
39. Waldo, G.S., Standish, B.M., Berendzen, J. and Terwilliger, T.C. (1999) Nat. Biotechnol., 17, 691-695.
40. Walker, R.G., Willingham, A.T. and Zuker, C.S. (2000) Science, 287, 2229-2234.
41. Wilkinson, D.L. and Harrison, R.G. (1991) Biotechnology (NY), 9, 443-448.
42. Wright, D.B., Banks, D.D., Lohman, J.R., Hilsenbeck, J.L. and Gloss, L.M. (2002) J. Mol. Biol., 323, 327-344.
43. Yang, A.S. and Honig, B. (1993) J. Mol. Biol., 231, 459-474.
44. Zhang, B. and Peng, Z. (2000) J. Mol. Biol., 299, 1121-1132.
45. Zhou, P., Lugovskoy, A.A. and Wagner, G. (2001) J. Biomol. NMR, 20, 11-14.
46. Zweifel, M.E. and Barrick, D. (2001) Biochemistry, 40, 14357-14367.