Crystal structure of the human Pax6 paired domain-DNA complex reveals specific roles for the linker region and carboxy-terminal subdomain in DNA binding

Genes and Development

Volumn 13, Issue 10, 1999, Pages 1263-1275

  Eric Xu, H ^a   Rould, Mark A ^a   Xu, Wenqing ^a   Epstein, Jonathan A ^b   Maas, Richard L ^b   Pabo, Carl O ^a  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Helix turn helix; Paired domain; Pax6; Protein DNA

Indexed keywords

TRANSCRIPTION FACTOR;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DNA BINDING; DNA CONFORMATION; DNA HELIX; GENE FUNCTION; GENE MAPPING; GENE MUTATION; HUMAN; MISSENSE MUTATION; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

EID: 0344731080     PISSN: 08909369     EISSN: None     Source Type: Journal    
DOI: 10.1101/gad.13.10.1263     Document Type: Article

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