-
1
-
-
0022904751
-
Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila
-
Bopp D, Burri M, Baumgartner S, Frigerio G, Noll M. Conservation of a large protein domain in the segmentation gene paired and in functionally related genes of Drosophila. Cell. 47:1986;1033-1040.
-
(1986)
Cell
, vol.47
, pp. 1033-1040
-
-
Bopp, D.1
Burri, M.2
Baumgartner, S.3
Frigerio, G.4
Noll, M.5
-
2
-
-
0024292631
-
Pax1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development
-
Deutsch U, Dressler GR, Gruss P. Pax1, a member of a paired box homologous murine gene family, is expressed in segmented structures during development. Cell. 53:1988;617-625.
-
(1988)
Cell
, vol.53
, pp. 617-625
-
-
Deutsch, U.1
Dressler, G.R.2
Gruss, P.3
-
4
-
-
0026734111
-
Pax in development
-
Gruss P, Walther C. Pax in development. Cell. 69:1992;719-722.
-
(1992)
Cell
, vol.69
, pp. 719-722
-
-
Gruss, P.1
Walther, C.2
-
5
-
-
0025942692
-
The molecular basis of the undulated/Pax-1 mutation
-
Chalepakis G, Fritsch R, Fickenscher H, Deutsch U, Goulding M, Gruss P. The molecular basis of the undulated/Pax-1 mutation. Cell. 66:1991;873-884.
-
(1991)
Cell
, vol.66
, pp. 873-884
-
-
Chalepakis, G.1
Fritsch, R.2
Fickenscher, H.3
Deutsch, U.4
Goulding, M.5
Gruss, P.6
-
6
-
-
0027426925
-
DNA sequence recognition by Pax proteins: Bipartite structure of the paired domain and its binding site
-
Czerny T, Schaffner G, Busslinger M. DNA sequence recognition by Pax proteins: bipartite structure of the paired domain and its binding site. Genes Dev. 7:1993;2048-2061.
-
(1993)
Genes Dev
, vol.7
, pp. 2048-2061
-
-
Czerny, T.1
Schaffner, G.2
Busslinger, M.3
-
7
-
-
0024277960
-
Undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax-1
-
Balling R, Deutsch U, Gruss P. Undulated, a mutation affecting the development of the mouse skeleton, has a point mutation in the paired box of Pax-1. Cell. 55:1988;531-535.
-
(1988)
Cell
, vol.55
, pp. 531-535
-
-
Balling, R.1
Deutsch, U.2
Gruss, P.3
-
8
-
-
0025925068
-
2H), a mutation affecting development of the mouse neural tube, shows a deletion with the paired homeodomain of Pax-3
-
2H), a mutation affecting development of the mouse neural tube, shows a deletion with the paired homeodomain of Pax-3. Cell. 67:1991;767-774.
-
(1991)
Cell
, vol.67
, pp. 767-774
-
-
Epstein, D.J.1
Vekemans, M.2
Gros, P.3
-
9
-
-
0027518348
-
Mutations in the PAX3 gene causing Weardenburg syndrome type 1 and type 2
-
Tassabehji M, Read AP, Newton VE, Patton M, Gruss P, Harris R, Strachan T. Mutations in the PAX3 gene causing Weardenburg syndrome type 1 and type 2. Nat Genet. 3:1993;26-30.
-
(1993)
Nat Genet
, vol.3
, pp. 26-30
-
-
Tassabehji, M.1
Read, A.P.2
Newton, V.E.3
Patton, M.4
Gruss, P.5
Harris, R.6
Strachan, T.7
-
10
-
-
0026340588
-
Pax-6, a murine paired box gene, is expressed in the developing CNS
-
Walther C, Gruss P. Pax-6, a murine paired box gene, is expressed in the developing CNS. Development. 113:1991;1435-1449.
-
(1991)
Development
, vol.113
, pp. 1435-1449
-
-
Walther, C.1
Gruss, P.2
-
11
-
-
0026345992
-
Mouse small eye results from mutations in a paired-like homeobox-containing gene
-
Hill RE, Favor J, Hogan BLM, Ton CCT, Saunders GF, Hanson IM, Prosser J, Jordan T, Hastie ND, Van Heyningen V. Mouse small eye results from mutations in a paired-like homeobox-containing gene. Nature. 354:1991;522-525.
-
(1991)
Nature
, vol.354
, pp. 522-525
-
-
Hill, R.E.1
Favor, J.2
Hogan, B.L.M.3
Ton, C.C.T.4
Saunders, G.F.5
Hanson, I.M.6
Prosser, J.7
Jordan, T.8
Hastie, N.D.9
Van Heyningen, V.10
-
12
-
-
0028175561
-
Uchida rat (rSey): A new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant
-
Fujiwara M, Uchida T, Osumi-Yamashita N, Eto K. Uchida rat (rSey): a new mutant rat with craniofacial abnormalities resembling those of the mouse Sey mutant. Differentiation. 57:1994;31-38.
-
(1994)
Differentiation
, vol.57
, pp. 31-38
-
-
Fujiwara, M.1
Uchida, T.2
Osumi-Yamashita, N.3
Eto, K.4
-
13
-
-
0026907123
-
The human PAX6 gene is mutated in two patients with aniridia
-
Jordan T, Hanson I, Zaletayev D, Hodgson S, Prosser J, Seawright A, Hastie N, Van Heyningen V. The human PAX6 gene is mutated in two patients with aniridia. Nat Genet. 1:1992;328-332.
-
(1992)
Nat Genet
, vol.1
, pp. 328-332
-
-
Jordan, T.1
Hanson, I.2
Zaletayev, D.3
Hodgson, S.4
Prosser, J.5
Seawright, A.6
Hastie, N.7
Van Heyningen, V.8
-
14
-
-
0025118546
-
Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system
-
Dressler GR, Deutsch U, Chowdhury K, Nornes HO, Gruss P. Pax2, a new murine paired-box-containing gene and its expression in the developing excretory system. Development. 109:1990;787-795.
-
(1990)
Development
, vol.109
, pp. 787-795
-
-
Dressler, G.R.1
Deutsch, U.2
Chowdhury, K.3
Nornes, H.O.4
Gruss, P.5
-
15
-
-
0028966947
-
Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux
-
Sanyanusin P, Schimmenti LA, McNoe LA, Ward TA, Pierpoint MEM, Sullivan MJ, Dobyns WB, Eccles MR. Mutation of the PAX2 gene in a family with optic nerve colobomas, renal anomalies and vesicoureteral reflux. Nat Genet. 9:1995;358-363.
-
(1995)
Nat Genet
, vol.9
, pp. 358-363
-
-
Sanyanusin, P.1
Schimmenti, L.A.2
McNoe, L.A.3
Ward, T.A.4
Pierpoint, M.E.M.5
Sullivan, M.J.6
Dobyns, W.B.7
Eccles, M.R.8
-
16
-
-
0029980113
-
Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma
-
Bennicelli JL, Edwards RH, Barr FG. Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma. Proc Natl Acad Sci USA. 93:1996;5455-5459.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5455-5459
-
-
Bennicelli, J.L.1
Edwards, R.H.2
Barr, F.G.3
-
17
-
-
0028364374
-
Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma
-
Davis RJ, DCruz CM, Lovell MA, Biegel JA, Barr FG. Fusion of PAX7 to FKHR by the variant t(1;13)(p36;q14) translocation in alveolar rhabdomyosarcoma. Cancer Res. 54:1994;2869-2872.
-
(1994)
Cancer Res
, vol.54
, pp. 2869-2872
-
-
Davis, R.J.1
DCruz, C.M.2
Lovell, M.A.3
Biegel, J.A.4
Barr, F.G.5
-
18
-
-
0027252649
-
The oncogenic potential of Pax genes
-
Maulbecker CC, Gruss P. The oncogenic potential of Pax genes. EMBO J. 12:1993;2361-2367.
-
(1993)
EMBO J
, vol.12
, pp. 2361-2367
-
-
Maulbecker, C.C.1
Gruss, P.2
-
19
-
-
0028207924
-
Roles of Pax-genes in developing and adult brain as suggested by expression patterns
-
Stoykova A, Gruss P. Roles of Pax-genes in developing and adult brain as suggested by expression patterns. J Neurosci. 14:1994;1395-1412.
-
(1994)
J Neurosci
, vol.14
, pp. 1395-1412
-
-
Stoykova, A.1
Gruss, P.2
-
20
-
-
0025875226
-
Pax-3, a novel murine DNA binding protein expressed during early neurogenesis
-
Goulding MD, Chalepkis G, Deutsch U, Erselius JR, Gruss P. Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J. 10:1991;1135-1147.
-
(1991)
EMBO J
, vol.10
, pp. 1135-1147
-
-
Goulding, M.D.1
Chalepkis, G.2
Deutsch, U.3
Erselius, J.R.4
Gruss, P.5
-
21
-
-
0025605289
-
The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system
-
Jostes B, Walther C, Gruss P. The murine paired box gene, Pax7, is expressed specifically during the development of the nervous and muscular system. Mech Dev. 33:1991;27-38.
-
(1991)
Mech Dev
, vol.33
, pp. 27-38
-
-
Jostes, B.1
Walther, C.2
Gruss, P.3
-
22
-
-
0002860934
-
Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development
-
Asano M, Gruss P. Pax-5 is expressed at the midbrain-hindbrain boundary during mouse development. Mech Dev. 33:1992;27-38.
-
(1992)
Mech Dev
, vol.33
, pp. 27-38
-
-
Asano, M.1
Gruss, P.2
-
23
-
-
0025125431
-
Spatially and temporally restricted expression of Pax2 during murine neurogenesis
-
Nornes HO, Dressler GR, Knapik EW, Deutsch U, Gruss P. Spatially and temporally restricted expression of Pax2 during murine neurogenesis. Development. 109:1990;797-809.
-
(1990)
Development
, vol.109
, pp. 797-809
-
-
Nornes, H.O.1
Dressler, G.R.2
Knapik, E.W.3
Deutsch, U.4
Gruss, P.5
-
24
-
-
0025084237
-
Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland
-
Plachov D, Chowdhury K, Walther C, Simon D, Guénet J-L, Gruss P. Pax8, a murine paired box gene expressed in the developing excretory system and thyroid gland. Development. 110:1990;643-651.
-
(1990)
Development
, vol.110
, pp. 643-651
-
-
Plachov, D.1
Chowdhury, K.2
Walther, C.3
Simon, D.4
Guénet, J.-L.5
Gruss, P.6
-
25
-
-
0027362452
-
Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggests a neuromeric organization
-
Puelles L, Rubenstein JLR. Expression patterns of homeobox and other putative regulatory genes in the embryonic mouse forebrain suggests a neuromeric organization. Trends Neurosci. 16:1993;472-479.
-
(1993)
Trends Neurosci
, vol.16
, pp. 472-479
-
-
Puelles, L.1
Rubenstein, J.L.R.2
-
26
-
-
0027967432
-
Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain
-
Macdonald R, Xu Q, Barth KA, Mikkola I, Holder N, Fjose A, Krauss S, Wilson SW. Regulatory gene expression boundaries demarcate sites of neuronal differentiation in the embryonic zebrafish forebrain. Neuron. 13:1994;1039-1053.
-
(1994)
Neuron
, vol.13
, pp. 1039-1053
-
-
Macdonald, R.1
Xu, Q.2
Barth, K.A.3
Mikkola, I.4
Holder, N.5
Fjose, A.6
Krauss, S.7
Wilson, S.W.8
-
28
-
-
0029855582
-
Forebrain patterning defects in Small eye mutant mice
-
of outstanding interest
-
Stoykova A, Walther C, Fritsch R, Gruss P. Forebrain patterning defects in Small eye mutant mice. of outstanding interest Development. 1996; This careful and exhaustive analysis of the small eye mutant mouse with various molecular markers brings new insights into mechanisms of brain patterning in relation to the prosomeric model and the role of Pax6 in this context.
-
(1996)
Development
-
-
Stoykova, A.1
Walther, C.2
Fritsch, R.3
Gruss, P.4
-
29
-
-
0029865062
-
Differential expression between Pax6 and En proteins in medulloblastoma
-
Vincent S, Turque N, Plaza S, Dhellemmes P, Hladky JP, Assaker R, Ruchoux MM, Saule S. Differential expression between Pax6 and En proteins in medulloblastoma. Int J Oncol. 8:1996;901-910.
-
(1996)
Int J Oncol
, vol.8
, pp. 901-910
-
-
Vincent, S.1
Turque, N.2
Plaza, S.3
Dhellemmes, P.4
Hladky, J.P.5
Assaker, R.6
Ruchoux, M.M.7
Saule, S.8
-
30
-
-
0027525512
-
Fate and potentialities of the avian mesencephalic/metencephalic neuroepithelium
-
Alvarado-Mallart R-M. Fate and potentialities of the avian mesencephalic/metencephalic neuroepithelium. J Neurobiol. 24:1993;1341-1355.
-
(1993)
J Neurobiol
, vol.24
, pp. 1341-1355
-
-
Alvarado-Mallart, R.-M.1
-
31
-
-
0029960330
-
Midbrain development induced by FGF8 in the chick embryo
-
of outstanding interest. Implantation of FGF8-coated beads into the forebrain mimics the effect of midbrain - hindbrain tissue grafts in inducing the expression of En2 and Wnt1 and the differentiation of mesencephalic-like structures. Accordingly, FGF8 is a major regulator of the formation of this brain territory, which is where it is normally expressed.
-
Crossley PH, Martinez S, Martin GR. Midbrain development induced by FGF8 in the chick embryo. of outstanding interest Nature. 380:1996;66-68 Implantation of FGF8-coated beads into the forebrain mimics the effect of midbrain - hindbrain tissue grafts in inducing the expression of En2 and Wnt1 and the differentiation of mesencephalic-like structures. Accordingly, FGF8 is a major regulator of the formation of this brain territory, which is where it is normally expressed.
-
(1996)
Nature
, vol.380
, pp. 66-68
-
-
Crossley, P.H.1
Martinez, S.2
Martin, G.R.3
-
32
-
-
0028959288
-
The mouse FGF8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
-
Crossley PH, Martin GR. The mouse FGF8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development. 121:1995;439-451.
-
(1995)
Development
, vol.121
, pp. 439-451
-
-
Crossley, P.H.1
Martin, G.R.2
-
33
-
-
0030069671
-
Engrailed, Wnt and Pax genes regulate midbrain - Hindbrain development
-
of outstanding interest. This review compares the phenotypes produced by mutations in Wnt1 and En1 with those produced by mutations in En2 and Pax5. The review also looks at the FGF8 expression pattern. The author proposes that a cascade of molecular interactions patterns the central nervous system at the midbrain - hindbrain boundary level.
-
Joyner AL. Engrailed, Wnt and Pax genes regulate midbrain - hindbrain development. of outstanding interest Trends Genet. 12:1996;15-20 This review compares the phenotypes produced by mutations in Wnt1 and En1 with those produced by mutations in En2 and Pax5. The review also looks at the FGF8 expression pattern. The author proposes that a cascade of molecular interactions patterns the central nervous system at the midbrain - hindbrain boundary level.
-
(1996)
Trends Genet
, vol.12
, pp. 15-20
-
-
Joyner, A.L.1
-
34
-
-
0026438292
-
Zebrafish pax[b] is involved in the formation of the midbrain - Hindbrain boundary
-
Krauss S, Maden M, Holder N, Wilson SW. Zebrafish pax[b] is involved in the formation of the midbrain - hindbrain boundary. Nature. 360:1992;87-89.
-
(1992)
Nature
, vol.360
, pp. 87-89
-
-
Krauss, S.1
Maden, M.2
Holder, N.3
Wilson, S.W.4
-
35
-
-
0027997502
-
Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP
-
Urbanek P, Wang ZQ, Fetka I, Wagner EF, Busslinger M. Complete block of early B cell differentiation and altered patterning of the posterior midbrain in mice lacking Pax5/BSAP. Cell. 79:1994;901-912.
-
(1994)
Cell
, vol.79
, pp. 901-912
-
-
Urbanek, P.1
Wang, Z.Q.2
Fetka, I.3
Wagner, E.F.4
Busslinger, M.5
-
37
-
-
0028864430
-
Midline signalling is required for Pax gene regulation and patterning of the eyes
-
of outstanding interest. Pax2 and Pax6 gene expressions were analyzed in zebrafish cyclop mutants in which the ventral axial mesoderm is affected, and when Shh was overexpressed in the developing wild-type central nervous system. A midline signalling molecule, possibly Shh, induces Pax2 expression and inhibits the expression of the Pax6 gene (see [38]).
-
MacDonald R, Barth KA, Xu Q, Holder N, Mikkola I, Wilson SW. Midline signalling is required for Pax gene regulation and patterning of the eyes. of outstanding interest Development. 121:1995;3267-3278 Pax2 and Pax6 gene expressions were analyzed in zebrafish cyclop mutants in which the ventral axial mesoderm is affected, and when Shh was overexpressed in the developing wild-type central nervous system. A midline signalling molecule, possibly Shh, induces Pax2 expression and inhibits the expression of the Pax6 gene (see [38]).
-
(1995)
Development
, vol.121
, pp. 3267-3278
-
-
MacDonald, R.1
Barth, K.A.2
Xu, Q.3
Holder, N.4
Mikkola, I.5
Wilson, S.W.6
-
38
-
-
0029347087
-
Patterning activities of vertebrate hedgehog proteins in the developing eye and brain
-
Ekker SC, Ungar AR, Greenstein P, Von Kessler DP, Porter JA, Moon RT, Beachy PA. Patterning activities of vertebrate hedgehog proteins in the developing eye and brain. Curr Biol. 5:1995;944-955.
-
(1995)
Curr Biol
, vol.5
, pp. 944-955
-
-
Ekker, S.C.1
Ungar, A.R.2
Greenstein, P.3
Von Kessler, D.P.4
Porter, J.A.5
Moon, R.T.6
Beachy, P.A.7
-
39
-
-
0027497981
-
Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord
-
Goulding MD, Lumsden A, Gruss P. Signals from the notochord and floor plate regulate the region-specific expression of two Pax genes in the developing spinal cord. Development. 117:1993;1001-1016.
-
(1993)
Development
, vol.117
, pp. 1001-1016
-
-
Goulding, M.D.1
Lumsden, A.2
Gruss, P.3
-
40
-
-
0029162584
-
Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm
-
Liem KF, Remml G, Roelink H, Jessel TM. Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm. Cell. 82:1995;969-979.
-
(1995)
Cell
, vol.82
, pp. 969-979
-
-
Liem, K.F.1
Remml, G.2
Roelink, H.3
Jessel, T.M.4
-
41
-
-
0029813240
-
Inhibition of floor plate differentiation by Pax3: Evidence from ectopic expression in transgenic mice
-
Tremblay P, Pituello F, Gruss P. Inhibition of floor plate differentiation by Pax3: evidence from ectopic expression in transgenic mice. Development. 122:1996;2555-2567.
-
(1996)
Development
, vol.122
, pp. 2555-2567
-
-
Tremblay, P.1
Pituello, F.2
Gruss, P.3
-
42
-
-
0027452611
-
The Splotch mutation interferes with muscle development in the limbs
-
Franz T, Kothary R, Surani MAH, Grim M. The Splotch mutation interferes with muscle development in the limbs. Anat Embryol. 187:1993;153-160.
-
(1993)
Anat Embryol
, vol.187
, pp. 153-160
-
-
Franz, T.1
Kothary, R.2
Surani, M.A.H.3
Grim, M.4
-
43
-
-
0030009337
-
Patterns of neuronal differentiation in neural tube mutant mice: Curly tail and Pax3 splotch-delayed
-
Keller-Peck CR, Mullen RJ. Patterns of neuronal differentiation in neural tube mutant mice: curly tail and Pax3 splotch-delayed. J Comp Neur. 368:1996;516-526.
-
(1996)
J Comp Neur
, vol.368
, pp. 516-526
-
-
Keller-Peck, C.R.1
Mullen, R.J.2
-
44
-
-
0029867255
-
-/- mutant mice
-
of special interest. Pax7-knockout mice produced by homologous recombinant carry defects in facial neural crest derivatives. This study leads to the conclusion that Pax7 is essential or very crucial for the development of only a restricted population of cephalic neural crests in which the gene is expressed. Functional redundancy between Pax3 and Pax7 is discussed in the paper.
-
-/- mutant mice. of special interest Development. 122:1996;831-838 Pax7-knockout mice produced by homologous recombinant carry defects in facial neural crest derivatives. This study leads to the conclusion that Pax7 is essential or very crucial for the development of only a restricted population of cephalic neural crests in which the gene is expressed. Functional redundancy between Pax3 and Pax7 is discussed in the paper.
-
(1996)
Development
, vol.122
, pp. 831-838
-
-
Mansouri, A.1
Stoykova, A.2
Torres, M.3
Gruss, P.4
-
45
-
-
0027170576
-
Evolution and role of Pax genes
-
Noll M. Evolution and role of Pax genes. Curr Opin Genet Dev. 3:1993;595-605.
-
(1993)
Curr Opin Genet Dev
, vol.3
, pp. 595-605
-
-
Noll, M.1
-
46
-
-
0029113766
-
Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal
-
of special interest. This study demonstrates that lack of gooseberry-distal transforms row five neuroblasts, where it is normally expressed, into row three neuroblasts, one of the other four rows that are normally present in each Drosophila segment. Inversely, ubiquitous expression of the same gene generates the reciprocal transformation, thus demonstrating that gooseberry-distal is one of the prime candidates for controlling specific neuroblast identity.
-
Skeath JB, Zhang Y, Holmgren R, Caroll SB, Doe CQ. Specification of neuroblast identity in the Drosophila embryonic central nervous system by gooseberry-distal. of special interest Nature. 376:1995;427-430 This study demonstrates that lack of gooseberry-distal transforms row five neuroblasts, where it is normally expressed, into row three neuroblasts, one of the other four rows that are normally present in each Drosophila segment. Inversely, ubiquitous expression of the same gene generates the reciprocal transformation, thus demonstrating that gooseberry-distal is one of the prime candidates for controlling specific neuroblast identity.
-
(1995)
Nature
, vol.376
, pp. 427-430
-
-
Skeath, J.B.1
Zhang, Y.2
Holmgren, R.3
Caroll, S.B.4
Doe, C.Q.5
-
47
-
-
0028216368
-
Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations in the epidermis and central nervous system
-
Zhang Y, Ungar A, Fresquez C, Holmgren R. Ectopic expression of either the Drosophila gooseberry-distal or proximal gene causes alterations in the epidermis and central nervous system. Development. 120:1994;1151-1161.
-
(1994)
Development
, vol.120
, pp. 1151-1161
-
-
Zhang, Y.1
Ungar, A.2
Fresquez, C.3
Holmgren, R.4
-
48
-
-
84995839584
-
Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells
-
Turque N, Plaza S, Radvanyi F, Carriere C, Saule S. Pax-QNR/Pax-6, a paired box- and homeobox-containing gene expressed in neurons, is also expressed in pancreatic endocrine cells. Mol Endocrinol. 8:1994;929-938.
-
(1994)
Mol Endocrinol
, vol.8
, pp. 929-938
-
-
Turque, N.1
Plaza, S.2
Radvanyi, F.3
Carriere, C.4
Saule, S.5
-
49
-
-
0030069119
-
Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation
-
Wallin J, Eibel H, Neubüser A, Wilting J, Koseki H, Balling R. Pax1 is expressed during development of the thymus epithelium and is required for normal T-cell maturation. Development. 122:1996;23-30.
-
(1996)
Development
, vol.122
, pp. 23-30
-
-
Wallin, J.1
Eibel, H.2
Neubüser, A.3
Wilting, J.4
Koseki, H.5
Balling, R.6
-
50
-
-
0028101943
-
Kidney and retinal defects (Krd), a transgene induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus
-
Keller SA, Jones JM, Boyle A, Barrow LL, Killen PD, Green DG, Kapousta NV, Hitchcock PF, Swank RT, Meisler MH. Kidney and retinal defects (Krd), a transgene induced mutation with a deletion of mouse chromosome 19 that includes the Pax2 locus. Genomics. 23:1994;309-320.
-
(1994)
Genomics
, vol.23
, pp. 309-320
-
-
Keller, S.A.1
Jones, J.M.2
Boyle, A.3
Barrow, L.L.4
Killen, P.D.5
Green, D.G.6
Kapousta, N.V.7
Hitchcock, P.F.8
Swank, R.T.9
Meisler, M.H.10
-
51
-
-
0027429223
-
Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development
-
Rothenpieler UW, Dressler GR. Pax-2 is required for mesenchyme-to-epithelium conversion during kidney development. Development. 119:1993;711-720.
-
(1993)
Development
, vol.119
, pp. 711-720
-
-
Rothenpieler, U.W.1
Dressler, G.R.2
-
52
-
-
0029590072
-
Pax-2 controls multiple steps of urogenital development
-
of special interest. Pax2-knockout mice lack kidneys, ureters and genital tracts. This study demonstrates that Pax2 is essential for the formation of kidney epithelium from the mesenchyme of the intermediate mesoderm (see also [51]).
-
Torres M, Gomez-Pardo E, Dressler GR, Gruss P. Pax-2 controls multiple steps of urogenital development. of special interest Development. 121:1995;4057-4065 Pax2-knockout mice lack kidneys, ureters and genital tracts. This study demonstrates that Pax2 is essential for the formation of kidney epithelium from the mesenchyme of the intermediate mesoderm (see also [51]).
-
(1995)
Development
, vol.121
, pp. 4057-4065
-
-
Torres, M.1
Gomez-Pardo, E.2
Dressler, G.R.3
Gruss, P.4
-
53
-
-
0028944665
-
Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila
-
of special interest. Targeted ectopic expression of the Drosophila eyeless gene or of the mouse Pax6 gene in various imaginal disc primordia of the Drosophila embryo leads to induction of ectopic eye structures in the wings, legs and antennae. These results support the conclusion that eyeless and the related Pax6 are master control genes for eye morphogenesis.
-
Halder G, Callaerts P, Gehring WJ. Induction of ectopic eyes by targeted expression of the eyeless gene in Drosophila. of special interest Science. 267:1995;1788-1792 Targeted ectopic expression of the Drosophila eyeless gene or of the mouse Pax6 gene in various imaginal disc primordia of the Drosophila embryo leads to induction of ectopic eye structures in the wings, legs and antennae. These results support the conclusion that eyeless and the related Pax6 are master control genes for eye morphogenesis.
-
(1995)
Science
, vol.267
, pp. 1788-1792
-
-
Halder, G.1
Callaerts, P.2
Gehring, W.J.3
-
54
-
-
0027965633
-
Homology of the eyeless gene of Drosophila to the small eye gene in mice and Aniridia in humans
-
Quiring R, Walldorf U, Kloter U, Gehring WJ. Homology of the eyeless gene of Drosophila to the small eye gene in mice and Aniridia in humans. Science. 265:1994;785-789.
-
(1994)
Science
, vol.265
, pp. 785-789
-
-
Quiring, R.1
Walldorf, U.2
Kloter, U.3
Gehring, W.J.4
-
55
-
-
0029002548
-
The role of Pax-6 in eye and nasal development
-
Grindley JC, Davidson DR, Hill RE. The role of Pax-6 in eye and nasal development. Development. 121:1995;1433-1442.
-
(1995)
Development
, vol.121
, pp. 1433-1442
-
-
Grindley, J.C.1
Davidson, D.R.2
Hill, R.E.3
-
56
-
-
0029979219
-
Multiple function for Pax6 in mouse eye and nasal development
-
of special interest. Using chimeras of sey mutant and wild-type cells, the authors observed that sey cells were excluded from lens and nasal epithelium in these chimeric animals, thus indicating that Pax6 is required in a cell-autonomous manner for the formation of these structures. The authors also confirm that Pax6 is also necessary for the proper formation of the optic cup (see also [55]).
-
Quinn JC, West JD, Hill RE. Multiple function for Pax6 in mouse eye and nasal development. of special interest Genes Dev. 10:1996;435-446 Using chimeras of sey mutant and wild-type cells, the authors observed that sey cells were excluded from lens and nasal epithelium in these chimeric animals, thus indicating that Pax6 is required in a cell-autonomous manner for the formation of these structures. The authors also confirm that Pax6 is also necessary for the proper formation of the optic cup (see also [55]).
-
(1996)
Genes Dev
, vol.10
, pp. 435-446
-
-
Quinn, J.C.1
West, J.D.2
Hill, R.E.3
-
57
-
-
0028301884
-
The role of Pax-1 in axial skeleton development
-
Wallin J, Wilting J, Koseki H, Fritsch R, Christ B, Balling R. The role of Pax-1 in axial skeleton development. Development. 120:1994;1109-1121.
-
(1994)
Development
, vol.120
, pp. 1109-1121
-
-
Wallin, J.1
Wilting, J.2
Koseki, H.3
Fritsch, R.4
Christ, B.5
Balling, R.6
-
58
-
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0028946524
-
Pax-1, a regulator of sclerotome development is induced by notochord and floor plate signals in avian embryos
-
Ebensperger C, Wilting J, Brand-Saberi B, Mizutani Y, Christ B, Balling R, Koseki H. Pax-1, a regulator of sclerotome development is induced by notochord and floor plate signals in avian embryos. Anat Embryol. 191:1995;297-310.
-
(1995)
Anat Embryol
, vol.191
, pp. 297-310
-
-
Ebensperger, C.1
Wilting, J.2
Brand-Saberi, B.3
Mizutani, Y.4
Christ, B.5
Balling, R.6
Koseki, H.7
-
59
-
-
0029041177
-
Long-range sclerotome induction by sonic hedgehog: Direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway
-
of special interest. Culture systems of presomitic mesoderm explants were used to demonstrate that Shh induces the expression of Pax1. In addition, different levels of Pax1 expression were induced by different concentrations of Shh. Inversely, the authors also report a repression of the expression of Pax3 in the Shh-treated explants.
-
Fan CM, Porter JA, Chiang C, Chang DT, Beachy PA, Tessier-Lavigne M. Long-range sclerotome induction by sonic hedgehog: direct role of the amino-terminal cleavage product and modulation by the cyclic AMP signaling pathway. of special interest Cell. 81:1995;457-465 Culture systems of presomitic mesoderm explants were used to demonstrate that Shh induces the expression of Pax1. In addition, different levels of Pax1 expression were induced by different concentrations of Shh. Inversely, the authors also report a repression of the expression of Pax3 in the Shh-treated explants.
-
(1995)
Cell
, vol.81
, pp. 457-465
-
-
Fan, C.M.1
Porter, J.A.2
Chiang, C.3
Chang, D.T.4
Beachy, P.A.5
Tessier-Lavigne, M.6
-
61
-
-
0027479540
-
1H) mutant mice using a lacZ transgene
-
1H) mutant mice using a lacZ transgene. Dev Brain Res. 72:1993;99-105.
-
(1993)
Dev Brain Res
, vol.72
, pp. 99-105
-
-
Franz, T.1
Kothary, R.2
-
62
-
-
84981841769
-
Analysis of the developmental effects of a lethal mutation in the house mouse
-
Auerbach R. Analysis of the developmental effects of a lethal mutation in the house mouse. J Exp Zool. 127:1954;305-329.
-
(1954)
J Exp Zool
, vol.127
, pp. 305-329
-
-
Auerbach, R.1
-
64
-
-
0026497586
-
PAX8, a human paired box gene: Isolation and expression in developing thyroid, kidney and Wilms' tumor
-
Poleev A, Fickenscher H, Mundlos S, Winterpacht A, Zabel B, Fidler A, Gruss P, Plachov D. PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumor. Development. 116:1992;611-623.
-
(1992)
Development
, vol.116
, pp. 611-623
-
-
Poleev, A.1
Fickenscher, H.2
Mundlos, S.3
Winterpacht, A.4
Zabel, B.5
Fidler, A.6
Gruss, P.7
Plachov, D.8
-
65
-
-
0026601176
-
Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor
-
Dressler GR, Douglass EC. Pax-2 is a DNA-binding protein expressed in embryonic kidney and Wilms tumor. Proc Natl Acad Sci USA. 89:1992;1179-1183.
-
(1992)
Proc Natl Acad Sci USA
, vol.89
, pp. 1179-1183
-
-
Dressler, G.R.1
Douglass, E.C.2
-
66
-
-
0027366917
-
Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma
-
Shapiro DN, Sublett JE, Li B, Downing JR, Naeve CW. Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. Cancer Res. 53:1993;5108-5112.
-
(1993)
Cancer Res
, vol.53
, pp. 5108-5112
-
-
Shapiro, D.N.1
Sublett, J.E.2
Li, B.3
Downing, J.R.4
Naeve, C.W.5
-
67
-
-
0029980113
-
Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma
-
Bonnicelli JL, Edwards RH, Barr FG. Mechanism for transcriptional gain of function resulting from chromosomal translocation in alveolar rhabdomyosarcoma. Proc Natl Acad Sci USA. 93:1996;5455-5459.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5455-5459
-
-
Bonnicelli, J.L.1
Edwards, R.H.2
Barr, F.G.3
-
68
-
-
0028969176
-
Pax-5 expression correlates with the increasing malignancy in human astrocytomas
-
Stuart ET, Kioussi C, Aguzzi A, Gruss P. Pax-5 expression correlates with the increasing malignancy in human astrocytomas. Clin Cancer Res. 1:1994;207-214.
-
(1994)
Clin Cancer Res
, vol.1
, pp. 207-214
-
-
Stuart, E.T.1
Kioussi, C.2
Aguzzi, A.3
Gruss, P.4
-
69
-
-
0029078066
-
Deregulated expression of PAX-5 in medulloblastoma
-
Kozmik Z, Sure U, Rüedi D, Busslinger M, Aguzzi A. Deregulated expression of PAX-5 in medulloblastoma. Proc Natl Acad Sci USA. 92:1995;5709-5713.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5709-5713
-
-
Kozmik, Z.1
Sure, U.2
Rüedi, D.3
Busslinger, M.4
Aguzzi, A.5
-
70
-
-
0029998350
-
Deregulation of PAX-5 by the Eμ enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphomas
-
Busslinger M, Klix N, Pfeffer P, Graninger PG, Kozmik Z. Deregulation of PAX-5 by the Eμ enhancer of the IgH locus adjacent to two alternative PAX-5 promoters in a diffuse large-cell lymphomas. Proc Natl Acad Sci USA. 93:1996;6129-6134.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 6129-6134
-
-
Busslinger, M.1
Klix, N.2
Pfeffer, P.3
Graninger, P.G.4
Kozmik, Z.5
-
71
-
-
0028196601
-
The B cell-specific transcription factor BSAP regulates B cell proliferation
-
Wakatsuki YW, Neurath MF, Max EE, Strober W. The B cell-specific transcription factor BSAP regulates B cell proliferation. J Exp Med. 179:1994;1099-1108.
-
(1994)
J Exp Med
, vol.179
, pp. 1099-1108
-
-
Wakatsuki, Y.W.1
Neurath, M.F.2
Max, E.E.3
Strober, W.4
-
72
-
-
0030039249
-
Two Pax binding sites are required for early embryonic brain expression of an Engrailed-2 transgene
-
of special interest. The En2 enhancer, which can direct β-galactosidase expression in the midbrain - hindbrain boundary of transgenic mice, has two binding sites for the Pax2, Pax5 and Pax8 proteins. Mutation or deletion of the two Pax5-binding sites abolishes the expression of lacz in this brain area of transgenic animals.
-
Song DL, Chelapakis G, Gruss P, Joyner AL. Two Pax binding sites are required for early embryonic brain expression of an Engrailed-2 transgene. of special interest Development. 122:1996;627-635 The En2 enhancer, which can direct β-galactosidase expression in the midbrain - hindbrain boundary of transgenic mice, has two binding sites for the Pax2, Pax5 and Pax8 proteins. Mutation or deletion of the two Pax5-binding sites abolishes the expression of lacz in this brain area of transgenic animals.
-
(1996)
Development
, vol.122
, pp. 627-635
-
-
Song, D.L.1
Chelapakis, G.2
Gruss, P.3
Joyner, A.L.4
-
73
-
-
0026601317
-
Two myogenic lineages in the developing somite
-
Ordahl CP, Le Douarin NM. Two myogenic lineages in the developing somite. Development. 114:1992;339-353.
-
(1992)
Development
, vol.114
, pp. 339-353
-
-
Ordahl, C.P.1
Le Douarin, N.M.2
-
74
-
-
0029914928
-
Pax3 modulates expression of the c-met receptor during limb muscle development
-
of special interest. Binding assay experiments identified the Pax3-binding site on the human c-met promoter. Furthermore, culture experiments demonstrated that Pax3 can stimulate c-met expression. These results are consistent with the observation that c-met is downregulated in splotch mice (see also [75]).
-
Epstein JA, Shapiro DN, Cheng J, Lam PY, Maas RL. Pax3 modulates expression of the c-met receptor during limb muscle development. of special interest Proc Natl Acad Sci USA. 93:1996;4213-4218 Binding assay experiments identified the Pax3-binding site on the human c-met promoter. Furthermore, culture experiments demonstrated that Pax3 can stimulate c-met expression. These results are consistent with the observation that c-met is downregulated in splotch mice (see also [75]).
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4213-4218
-
-
Epstein, J.A.1
Shapiro, D.N.2
Cheng, J.3
Lam, P.Y.4
Maas, R.L.5
-
75
-
-
0029134104
-
Essential role for the c-met receptor in the migration of myogenic precursor cells in the limb bud
-
Bladt F, Riethmacher D, Isenmann S, Aguzzi A, Birchmeier C. Essential role for the c-met receptor in the migration of myogenic precursor cells in the limb bud. Nature. 376:1995;768-771.
-
(1995)
Nature
, vol.376
, pp. 768-771
-
-
Bladt, F.1
Riethmacher, D.2
Isenmann, S.3
Aguzzi, A.4
Birchmeier, C.5
-
76
-
-
0026698147
-
Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis
-
Adams B, Dörfler P, Aguzzi A, Kozmik Z, Urbánek P, Maurer-Fogy I, Busslinger M. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6:1992;1589-1607.
-
(1992)
Genes Dev
, vol.6
, pp. 1589-1607
-
-
Adams, B.1
Dörfler, P.2
Aguzzi, A.3
Kozmik, Z.4
Urbánek, P.5
Maurer-Fogy, I.6
Busslinger, M.7
-
77
-
-
0026738482
-
Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters
-
Zannini M, Francis-Lang H, Plachov D, Di Lauro R. Pax-8, a paired domain-containing protein, binds to a sequence overlapping the recognition site of a homeodomain and activates transcription from two thyroid-specific promoters. Mol Cell Biol. 12:1992;4230-4241.
-
(1992)
Mol Cell Biol
, vol.12
, pp. 4230-4241
-
-
Zannini, M.1
Francis-Lang, H.2
Plachov, D.3
Di Lauro, R.4
-
78
-
-
0028809870
-
Loss of p53 function through PAX-mediated transcriptional repression
-
Stuart ET, Haffner R, Oren M, Gruss P. Loss of p53 function through PAX-mediated transcriptional repression. EMBO J. 14:1995;5638-5645.
-
(1995)
EMBO J
, vol.14
, pp. 5638-5645
-
-
Stuart, E.T.1
Haffner, R.2
Oren, M.3
Gruss, P.4
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