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1
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0035377458
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Post-translational modifications of proteins: Acetylcholinesterase as a model system
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Nalivaeva NN, Turner AJ: Post-translational modifications of proteins: acetylcholinesterase as a model system. Proteomics 2001, 1:735-747.
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(2001)
Proteomics
, vol.1
, pp. 735-747
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Nalivaeva, N.N.1
Turner, A.J.2
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3
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0035955697
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The biology and enzymology of protein N-myristoylation
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Farazi TA, Waksman G, Gordon JI: The biology and enzymology of protein N-myristoylation. J Biol Chem 2001, 276:39501-39504.
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(2001)
J Biol Chem
, vol.276
, pp. 39501-39504
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Farazi, T.A.1
Waksman, G.2
Gordon, J.I.3
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4
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0036547672
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Glycosylphosphatidylinositol (GPI)-anchored proteins
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Ikezawa H: Glycosylphosphatidylinositol (GPI)-anchored proteins. Biol Pharm Bull 2002, 25:409-417.
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(2002)
Biol Pharm Bull
, vol.25
, pp. 409-417
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Ikezawa, H.1
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5
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0034630098
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Recent advances in the study of prenylated proteins
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Sinensky M: Recent advances in the study of prenylated proteins. Biochim Biophys Acta 2000, 1484:93-106.
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(2000)
Biochim Biophys Acta
, vol.1484
, pp. 93-106
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Sinensky, M.1
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7
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0037470819
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Protein prenylation: A pivotal posttranslational process
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Roskoski R Jr: Protein prenylation: a pivotal posttranslational process. Biochem Biophys Res Commun 2003, 303:1-7.
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(2003)
Biochem Biophys Res Commun
, vol.303
, pp. 1-7
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Roskoski Jr., R.1
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8
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0035751462
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Farnesylated proteins and cell cycle progression
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Tamanoi F, Kato-Stankiewicz J, Jiang C, Machado I, Thapar N: Farnesylated proteins and cell cycle progression. J Cell Biochem Suppl 2001, 37:64-70.
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(2001)
J Cell Biochem Suppl
, vol.37
, pp. 64-70
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Tamanoi, F.1
Kato-Stankiewicz, J.2
Jiang, C.3
Machado, I.4
Thapar, N.5
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10
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0036785539
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A prenylation inhibitor prevents production of infectious hepatitis delta virus particles
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Bordier BB, Marion PL, Ohashi K, Kay MA, Greenberg HB, Casey JL, Glenn JS: A prenylation inhibitor prevents production of infectious hepatitis delta virus particles. J Virol 2002, 76:10465-10472.
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(2002)
J Virol
, vol.76
, pp. 10465-10472
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Bordier, B.B.1
Marion, P.L.2
Ohashi, K.3
Kay, M.A.4
Greenberg, H.B.5
Casey, J.L.6
Glenn, J.S.7
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11
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0037146884
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Secretion of apolipoprotein e by brain glia requires protein prenylation and is suppressed by statins
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Naidu A, Xu Q, Catalano R, Cordell B: Secretion of apolipoprotein E by brain glia requires protein prenylation and is suppressed by statins. Brain Res 2002, 958:100-111.
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(2002)
Brain Res
, vol.958
, pp. 100-111
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Naidu, A.1
Xu, Q.2
Catalano, R.3
Cordell, B.4
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12
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0034672686
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Functional aspects of polyisoprenoid protein substituents: Roles in protein-protein interaction and trafficking
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Sinensky M: Functional aspects of polyisoprenoid protein substituents: roles in protein-protein interaction and trafficking. Biochim Biophys Acta 2000, 1529:203-209.
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(2000)
Biochim Biophys Acta
, vol.1529
, pp. 203-209
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Sinensky, M.1
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13
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0035861547
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2-terminal processing of the yeast a-factor precursor
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2-terminal processing of the yeast a-factor precursor. J Biol Chem 2001, 276:46798-46806.
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(2001)
J Biol Chem
, vol.276
, pp. 46798-46806
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Tam, A.1
Schmidt, W.K.2
Michaelis, S.3
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14
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0035800833
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Biochemical studies of Zmpste24-deficient mice
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Leung GK, Schmidt WK, Bergo MO, Gavino B, Wong DH, Tam A, Ashby MN, Michaelis S, Young SG: Biochemical studies of Zmpste24-deficient mice. J Biol Chem 2001, 276:29051-29058.
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(2001)
J Biol Chem
, vol.276
, pp. 29051-29058
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Leung, G.K.1
Schmidt, W.K.2
Bergo, M.O.3
Gavino, B.4
Wong, D.H.5
Tam, A.6
Ashby, M.N.7
Michaelis, S.8
Young, S.G.9
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15
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0036791026
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Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect
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Bergo MO, Gavino B, Ross J, Schmidt WK, Hong C, Kendall LV, Mohr A, Meta M, Genant H, Jiang Y et al.: Zmpste24 deficiency in mice causes spontaneous bone fractures, muscle weakness, and a prelamin A processing defect. Proc Natl Acad Sci USA 2002, 99:13049-13054. This article provides new information on the role of the CaaX-protease STE24 in mammalian development. Zmpste24-deficient mice present muscle weakness that is caused by a defect in prelamin A processing. The absence of STE24 also results in multiple bone fractures, suggesting the involvement of the CaaX-protease in the processing of other protein substrates that are involved in bone development or structural integrity.
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(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 13049-13054
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Bergo, M.O.1
Gavino, B.2
Ross, J.3
Schmidt, W.K.4
Hong, C.5
Kendall, L.V.6
Mohr, A.7
Meta, M.8
Genant, H.9
Jiang, Y.10
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16
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0037444824
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Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans
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Cadinanos J, Schmidt WK, Fueyo A, Varela I, Lopez-Otin C, Freije JM: Identification, functional expression and enzymic analysis of two distinct CaaX proteases from Caenorhabditis elegans. Biochem J 2003, 370:1047-1054.
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(2003)
Biochem J
, vol.370
, pp. 1047-1054
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Cadinanos, J.1
Schmidt, W.K.2
Fueyo, A.3
Varela, I.4
Lopez-Otin, C.5
Freije, J.M.6
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17
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0034119314
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The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities
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Trueblood CE, Boyartchuk VL, Picologlou EA, Rozema D, Poulter CD, Rine J: The CaaX proteases, Afc1p and Rce1p, have overlapping but distinct substrate specificities. Mol Cell Biol 2000, 20:4381-4392.
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(2000)
Mol Cell Biol
, vol.20
, pp. 4381-4392
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Trueblood, C.E.1
Boyartchuk, V.L.2
Picologlou, E.A.3
Rozema, D.4
Poulter, C.D.5
Rine, J.6
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18
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0036132907
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Absence of the CAAX endoprotease Rce1: Effects on cell growth and transformation
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Bergo MO, Ambroziak P, Gregory C, George A, Otto JC, Kim E, Nagase H, Casey PJ, Balmain A, Young SG: Absence of the CAAX endoprotease Rce1: effects on cell growth and transformation. Mol Cell Biol 2002, 22:171-181.
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(2002)
Mol Cell Biol
, vol.22
, pp. 171-181
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Bergo, M.O.1
Ambroziak, P.2
Gregory, C.3
George, A.4
Otto, J.C.5
Kim, E.6
Nagase, H.7
Casey, P.J.8
Balmain, A.9
Young, S.G.10
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19
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0037119482
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The Arabidopsis AtSTE24 is a CAAX protease with broad substrate specificity
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Bracha K, Lavy M, Yalovsky S: The Arabidopsis AtSTE24 is a CAAX protease with broad substrate specificity. J Biol Chem 2002, 277:29856-29864. The specific removal of the three carboxy-terminal residues of the CaaX-box-containing proteins in mammals and yeast is catalyzed by two different endoproteases, STE24 and RCE1. In this work, the authors demonstrated the presence of a STE24 homolog in plants. The substrate specificity of the enzyme and the absence of RCE1 from plants suggest that plants possess a single functional CaaX-protease.
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(2002)
J Biol Chem
, vol.277
, pp. 29856-29864
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Bracha, K.1
Lavy, M.2
Yalovsky, S.3
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20
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0034490131
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Carboxyl-methylation of prenylated calmodulin CaM53 is required for efficient plasma membrane targeting of the protein
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Rodriguez-Concepcion M, Toledo-Ortiz G, Yalovsky S, Caldelari D, Gruissem W: Carboxyl-methylation of prenylated calmodulin CaM53 is required for efficient plasma membrane targeting of the protein. Plant J 2000, 24:775-784.
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(2000)
Plant J
, vol.24
, pp. 775-784
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Rodriguez-Concepcion, M.1
Toledo-Ortiz, G.2
Yalovsky, S.3
Caldelari, D.4
Gruissem, W.5
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21
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0037064133
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Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver
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Beigneux A, Withycombe SK, Digits JA, Tschantz WR, Weinbaum CA, Griffey SM, Bergo M, Casey PJ, Young SG: Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver. J Biol Chem 2002, 277:38358-38363.
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(2002)
J Biol Chem
, vol.277
, pp. 38358-38363
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Beigneux, A.1
Withycombe, S.K.2
Digits, J.A.3
Tschantz, W.R.4
Weinbaum, C.A.5
Griffey, S.M.6
Bergo, M.7
Casey, P.J.8
Young, S.G.9
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22
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0033735850
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Functional implications of protein isoprenylation in plants
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Crowell DN: Functional implications of protein isoprenylation in plants. Prog Lipid Res 2000, 39:393-408.
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(2000)
Prog Lipid Res
, vol.39
, pp. 393-408
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Crowell, D.N.1
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23
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0033834826
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Prenylation of the floral transcription factor APETALA1 modulates its function
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Yalovsky S, Rodriguez-Concepcion M, Bracha K, Toledo-Ortiz G, Gruissem W: Prenylation of the floral transcription factor APETALA1 modulates its function. Plant Cell 2000, 12:1257-1266.
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(2000)
Plant Cell
, vol.12
, pp. 1257-1266
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Yalovsky, S.1
Rodriguez-Concepcion, M.2
Bracha, K.3
Toledo-Ortiz, G.4
Gruissem, W.5
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24
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0036802456
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A cell-specific, prenylation-independent mechanism regulates targeting of type II RACs
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Lavy M, Bracha-Drori K, Sternberg H, Yalovsky S: A cell-specific, prenylation-independent mechanism regulates targeting of type II RACs. Plant Cell 2002, 14:2431-2450. The authors show that the targeting of three Arabidopsis Type-II RAC proteins to the plasma membrane requires palmytoylation, but is independent of the farnesylation status of the protein. They also demonstrate that AtRAC8 and AtRAC10 are not prenylated, despite the presence of a CaaX-box in these proteins.
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(2002)
Plant Cell
, vol.14
, pp. 2431-2450
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Lavy, M.1
Bracha-Drori, K.2
Sternberg, H.3
Yalovsky, S.4
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25
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0036776292
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Functional characterization of a heavy metal binding protein Cdl19 from Arabidopsis
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Suzuki N, Yamaguchi Y, Koizumi N, Sano H: Functional characterization of a heavy metal binding protein Cdl19 from Arabidopsis. Plant J 2002, 32:165-173.
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(2002)
Plant J
, vol.32
, pp. 165-173
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Suzuki, N.1
Yamaguchi, Y.2
Koizumi, N.3
Sano, H.4
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26
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0035080304
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Analysis of PEAM4, the pea AP1 functional homologue, supports a model for API-like genes controlling both floral meristem and floral organ identity in different plant species
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Berbel A, Navarro C, Ferrandiz C, Canas LA, Madueno F, Beltran JP: Analysis of PEAM4, the pea AP1 functional homologue, supports a model for API-like genes controlling both floral meristem and floral organ identity in different plant species. Plant J 2001, 25:441-451.
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(2001)
Plant J
, vol.25
, pp. 441-451
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Berbel, A.1
Navarro, C.2
Ferrandiz, C.3
Canas, L.A.4
Madueno, F.5
Beltran, J.P.6
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27
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0033823696
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Functional requirement of plant farnesyltransferase during development in Arabidopsis
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Yalovsky S, Kulukian A, Rodriguez-Concepcion M, Young CA, Gruissem W: Functional requirement of plant farnesyltransferase during development in Arabidopsis. Plant Cell 2000, 12:1267-1278.
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(2000)
Plant Cell
, vol.12
, pp. 1267-1278
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Yalovsky, S.1
Kulukian, A.2
Rodriguez-Concepcion, M.3
Young, C.A.4
Gruissem, W.5
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28
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0034870820
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Efficient prenylation by a plant geranylgeranyltransferase-I requires a functional CaaL box motif and a proximal polybasic domain
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Caldelari D, Sternberg H, Rodriguez-Concepcion M, Gruissem W, Yalovsky S: Efficient prenylation by a plant geranylgeranyltransferase-I requires a functional CaaL box motif and a proximal polybasic domain. Plant Physiol 2001, 126:1416-1429.
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(2001)
Plant Physiol
, vol.126
, pp. 1416-1429
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Caldelari, D.1
Sternberg, H.2
Rodriguez-Concepcion, M.3
Gruissem, W.4
Yalovsky, S.5
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29
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0035984062
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Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltransferase mutant era1-2
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Allen GJ, Murata Y, Chu SP, Nafisi M, Schroeder JI: Hypersensitivity of abscisic acid-induced cytosolic calcium increases in the Arabidopsis farnesyltransferase mutant era1-2. Plant Cell 2002, 14:1649-1662. The authors of this article provide further insights into the role of protein farnesylation in ABA signaling. Treatment of the era1-2 mutant with ABA increases stomatal closure and cytosolic calcium concentration in guard cells, demonstrating that protein farnesylation is a negative regulator of ABA signaling and placing the regulatory protein between ABA perception and the activation of calcium channels.
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(2002)
Plant Cell
, vol.14
, pp. 1649-1662
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Allen, G.J.1
Murata, Y.2
Chu, S.P.3
Nafisi, M.4
Schroeder, J.I.5
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30
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0037147207
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Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway
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Stamatakis K, Cernuda-Morollon E, Hernandez-Perera O, Perez-Sala D: Isoprenylation of RhoB is necessary for its degradation. A novel determinant in the complex regulation of RhoB expression by the mevalonate pathway. J Biol Chem 2002, 277:49389-49396.
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(2002)
J Biol Chem
, vol.277
, pp. 49389-49396
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Stamatakis, K.1
Cernuda-Morollon, E.2
Hernandez-Perera, O.3
Perez-Sala, D.4
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31
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0038243185
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Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana
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Laule O, Furholz A, Chang HS, Zhu T, Wang X, Heifetz PB, Gruissem W, Lange M: Crosstalk between cytosolic and plastidial pathways of isoprenoid biosynthesis in Arabidopsis thaliana. Proc Natl Acad Sci USA 2003, 100:6866-6871. This work provides evidence of flux between the two isoprenoid biosynthetic pathways in Arabidopsis. Furthermore, flux from the chloroplast to the cytoplasm appears to be more effective in compensating for metabolic imbalances.
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(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 6866-6871
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Laule, O.1
Furholz, A.2
Chang, H.S.3
Zhu, T.4
Wang, X.5
Heifetz, P.B.6
Gruissem, W.7
Lange, M.8
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32
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0037276552
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Protein prenyltransferases
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Maurer-Stroh S, Washietl S, Eisenhaber F: Protein prenyltransferases. Genome Biol 2003, 4:212. The authors review the evolutionary history, structural characteristics and functions of protein prenyltransferases. In particular, this article raises the possibility of regulating prenyltransferases by alternative splicing.
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(2003)
Genome Biol
, vol.4
, pp. 212
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Maurer-Stroh, S.1
Washietl, S.2
Eisenhaber, F.3
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