Prenylcysteine lyase deficiency in mice results in the accumulation of farnesylcysteine and geranylgeranylcysteine in brain and liver

Journal of Biological Chemistry

Volumn 277, Issue 41, 2002, Pages 38358-38363

  Beigneux, Anne ^a,e   Withycombe, Shannon K ^a   Digits, Jennifer A ^b   Tschantz, William R ^c   Weinbaum, Carolyn A ^a   Griffey, Stephen M ^d   Bergo, Martin ^a   Casey, Patrick J ^a,b   Young, Stephen G ^a,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b DUKE UNIVERSITY MEDICAL CENTER   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e GLADSTONE INSTITUTE OF CARDIOVASCULAR DISEASE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDES; BIOLOGICAL ORGANS; BRAIN; ENZYMES; LIPIDS; MASS SPECTROMETRY; PATHOLOGY; PHYSIOLOGY; TISSUE;

CELL LINES;

BIOCHEMISTRY;

AMINO ACID; FARNESYLCYSTEINE; GERANYLGERANYLCYSTEINE; LYASE; PRENYLCYSTEINE LYASE; UNCLASSIFIED DRUG;

AMINO ACID METABOLISM; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN; CELL CULTURE; CELL GROWTH; CONTROLLED STUDY; CULTURE MEDIUM; ENZYME ACTIVITY; ENZYME DEFICIENCY; FIBROBLAST; GROWTH INHIBITION; HEART; IN VITRO STUDY; KIDNEY; LIVER; MASS SPECTROMETRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

AMINO ACID SEQUENCE; ANIMALS; BRAIN; CARBON-SULFUR LYASES; CYSTEINE; FIBROBLASTS; HUMANS; LIVER; MICE; MICE, KNOCKOUT; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; SEQUENCE ALIGNMENT; STEM CELLS; TISSUE DISTRIBUTION;

ANIMALIA; MAMMALIA;

EID: 0037064133     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M205183200     Document Type: Article

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