Design and pharmacology of peptoids and peptide-peptoid hybrids based on the melanocortin agonists core tetrapeptide sequence

Bioorganic and Medicinal Chemistry Letters

Volumn 13, Issue 24, 2003, Pages 4505-4509

  Holder, Jerry Ryan ^a   Bauzo, Rayna M ^a   Xiang, Zhimin ^a   Scott, Joseph ^a   Haskell Luevano, Carrie ^a  

^a UNIVERSITY OF FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLHISTIDYLPHENYLALANYLARGINYLTRYPTOPHANAMIDE; MELANOCORTIN 1 RECEPTOR; MELANOCORTIN 3 RECEPTOR; MELANOCORTIN 5 RECEPTOR; OLIGOMER; PEPTIDE DERIVATIVE; TETRAPEPTIDE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG DESIGN; DRUG SYNTHESIS; EMBRYO; FIBROBLAST; HUMAN; HUMAN CELL; MOUSE; NONHUMAN;

EID: 0344495976     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.08.078     Document Type: Article

References (28)

1. Cone R.D., Lu D., Koppula S., Vage D.I., Klungland H., Boston B., Chen W., Orth D.N., Pouton C., Kesterson R.A. Recent Prog. Horm. Res. 51:1996;287. (discussion 318).
2. The Melanocortin Receptors; Cone, R. D., Ed.; The Humana Press Inc.: New Jersey, 2000.
3. Chen A.S., Marsh D.J., Trumbauer M.E., Frazier E.G., Guan X.M., Yu H., Rosenblum C.I., Vongs A., Feng Y., Cao L.H., Metzger J.M., Strack A.M., Camacho R.E., Mellin T.N., Nunes C.N., Min W., Fisher J., Gopal-Truter S., MacIntyre D.E., Chen H.Y., Van der Ploeg L.H.T. Nat. Genet. 26:2000;97.
4. Butler A.A., Kesterson R.A., Khong K., Cullen M.J., Pelleymounter M.A., Dekoning J., Baetscher M., Cone R.D. Endocrinology. 141:2000;3518.
5. Huszar D., Lynch C.A., FairchildHuntress V., Dunmore J.H., Fang Q., Berkemeier L.R., Gu W., Kesterson R.A., Boston B.A., Cone R.D., Smith F.J., Campfield L.A., Burn P., Lee F. Cell. 88:1997;131.
6. Adessi C., Soto C. Curr. Med. Chem. 9:2002;963.
7. Hruby V.J., Balse P.M. Curr. Med. Chem. 7:2000;945.
8. Miller S.M., Simon R.J., Ng S., Zuckermann R.N., Kerr J.M., Moos W.H. Bioorg. Med. Chem. Lett. 4:1994;2657.
9. Miller S.M., Simon R.J., Ng S., Zuckermann R.N., Kerr J.M., Moos W.H. Drug Develop. Res. 35:1995;20.
10. Zuckermann R.N.K., Janice M., Kent S.B.H., Moos W.H. J. Am. Chem. Soc. 114:1992;10646.
11. Zuckermann R.N., Martin E.J., Spellmeyer D.C., Stauber G.B., Shoemaker K.R., Kerr J.M., Figliozzi G.M., Goff D.A., Siani M.A., Simon R.J., Banville S.C., Brown E.G., Wang L., Richter L.S., Moos W.H. J. Med. Chem. 37:1994;2678.
12. Heizmann G., Hildebrand P., Tanner H., Ketterer S., Pansky A., Froidevaux S., Beglinger C., Eberle A.N. J. Receptor Signal Transduct. Res. 19:1999;449.
13. Carpino L.A., Han G.Y. J. Am. Chem. Soc. 92:1970;5748.
14. Carpino L.A., Han G.Y. J. Org. Chem. 37:1972;3404.
15. Chen W., Shields T.S., Stork P.J., Cone R.D.A. Anal. Biochem. 226:1995;349.
16. Haskell-Luevano C., Cone R.D., Monck E.K., Wan Y.P. Biochemistry. 40:2001;6164.
17. Kruijtzer J.A.W., Hofmeyer L.J.F., Heerma W., Versluis C., Liskamp R.M.J. Chem. Euro. J. 4:1998;1570.
18. Simon R.J., Kania R.S., Zuckermann R.N., Huebner V.D., Jewell D.A., Banville S., Ng S., Wang L., Rosenberg S., Marlowe C.K., Spellmeyer D.C., Tan R.Y., Frankel A.D., Santi D.V., Cohen F.E., Bartlett P.A. Proc. Natl. Acad. Sci. U.S.A. 89:1992;9367.
19. Holder J.R., Xiang Z., Bauzo R.M., Haskell-Luevano C. J. Med. Chem. 45:2002;5736.
20. Holder J.R., Marques F.F., Bauzo R.M., Xiang Z., Haskell-Luevano C. Euro. J. Pharmacol. 462:2003;41.
21. Holder J.R., Bauzo R.M., Xiang Z., Haskell-Luevano C. Peptides. 24:2003;73.
22. Holder J.R., Bauzo R.M., Xiang Z., Haskell-Luevano C. J. Med. Chem. 45:2002;3073.
23. Holder J.R., Bauzo R.M., Xiang Z., Haskell-Luevano C. J. Med. Chem. 45:2002;2801.
24. Ruijtenbeek R., Kruijtzer J.A.W., van de Wiel W., Fischer M.J.E., Fluck M., Redegeld F.A.M., Liskamp R.M.J., Nijkamp F.P. Chembiochem. 2:2001;171.
25. Horwell D.C. Trends Biotechnol. 13:1995;132.
26. Al-Obeidi F., O'Connor S.D., Job C., Hruby V.J., Pettitt B.M. J. Pept. Res. 51:1998;420.
27. Richardson J.S. Adv. Protein Chem. 34:1981;167.
28. de Haan E.C., Wauben M.H.M., Grosfeld-Stulemeyer M.C., Kruijtzer J.A.W., Liskamp R.M.J., Moret E.E. Bioorg. Med. Chem. 10:2002;1939.